LOCUS       NM_145562               2100 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus prostate androgen-regulated mucin-like protein 1
            (Parm1), mRNA.
ACCESSION   NM_145562
VERSION     NM_145562.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2100)
  AUTHORS   He,Z., Chang,T., Chen,Y., Wang,H., Dai,L. and Zeng,H.
  TITLE     PARM1 Drives Smooth Muscle Cell Proliferation in Pulmonary Arterial
            Hypertension via AKT/FOXO3A Axis
  JOURNAL   Int J Mol Sci 24 (7), 6385 (2023)
   PUBMED   37047359
  REMARK    GeneRIF: PARM1 Drives Smooth Muscle Cell Proliferation in Pulmonary
            Arterial Hypertension via AKT/FOXO3A Axis.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2100)
  AUTHORS   Gao,C., Zhang,L., Chen,E. and Zhang,W.
  TITLE     Aqp2+ Progenitor Cells Maintain and Repair Distal Renal Segments
  JOURNAL   J Am Soc Nephrol 33 (7), 1357-1376 (2022)
   PUBMED   35318267
REFERENCE   3  (bases 1 to 2100)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2100)
  AUTHORS   Lodato,S., Molyneaux,B.J., Zuccaro,E., Goff,L.A., Chen,H.H.,
            Yuan,W., Meleski,A., Takahashi,E., Mahony,S., Rinn,J.L.,
            Gifford,D.K. and Arlotta,P.
  TITLE     Gene co-regulation by Fezf2 selects neurotransmitter identity and
            connectivity of corticospinal neurons
  JOURNAL   Nat Neurosci 17 (8), 1046-1054 (2014)
   PUBMED   24997765
REFERENCE   5  (bases 1 to 2100)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   6  (bases 1 to 2100)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   7  (bases 1 to 2100)
  AUTHORS   Shimogori,T., Lee,D.A., Miranda-Angulo,A., Yang,Y., Wang,H.,
            Jiang,L., Yoshida,A.C., Kataoka,A., Mashiko,H., Avetisyan,M.,
            Qi,L., Qian,J. and Blackshaw,S.
  TITLE     A genomic atlas of mouse hypothalamic development
  JOURNAL   Nat Neurosci 13 (6), 767-775 (2010)
   PUBMED   20436479
REFERENCE   8  (bases 1 to 2100)
  AUTHORS   Song,S.H., Hong,Y.H., Sasaki,S., Roh,S.G. and Katoh,K.
  TITLE     Prostatic androgen-repressed message-1 as a regulator of adipocyte
            differentiation in the mouse
  JOURNAL   Tohoku J Exp Med 219 (4), 311-317 (2009)
   PUBMED   19966531
  REMARK    GeneRIF: These results indicate that mPARM-1 might be involved in
            the regulation of fat accumulation and adipocyte differentiation.
REFERENCE   9  (bases 1 to 2100)
  AUTHORS   Rock,J.R., Lopez,M.C., Baker,H.V. and Harfe,B.D.
  TITLE     Identification of genes expressed in the mouse limb using a novel
            ZPA microarray approach
  JOURNAL   Gene Expr Patterns 8 (1), 19-26 (2007)
   PUBMED   17911046
REFERENCE   10 (bases 1 to 2100)
  AUTHORS   Kuninger,D., Kuzmickas,R., Peng,B., Pintar,J.E. and Rotwein,P.
  TITLE     Gene discovery by microarray: identification of novel genes induced
            during growth factor-mediated muscle cell survival and
            differentiation
  JOURNAL   Genomics 84 (5), 876-889 (2004)
   PUBMED   15475267
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC122216.4 and
            AC115723.13.
            
            On Nov 17, 2006 this sequence version replaced NM_145562.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC006604.1, AK161172.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-258               AC122216.4         101012-101269       c
            259-942             AC122216.4         24468-25151         c
            943-1021            AC122216.4         5893-5971           c
            1022-2100           AC115723.13        142008-143086       c
FEATURES             Location/Qualifiers
     source          1..2100
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 44.78 cM"
     gene            1..2100
                     /gene="Parm1"
                     /gene_synonym="2210012L08Rik; 9130213B05Rik"
                     /note="prostate androgen-regulated mucin-like protein 1"
                     /db_xref="GeneID:231440"
                     /db_xref="MGI:MGI:2443349"
     exon            1..258
                     /gene="Parm1"
                     /gene_synonym="2210012L08Rik; 9130213B05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             216..1106
                     /gene="Parm1"
                     /gene_synonym="2210012L08Rik; 9130213B05Rik"
                     /note="prostate androgen-regulated mucin-like protein 1
                     homolog; prostatic androgen-repressed message-1; PARM-1"
                     /codon_start=1
                     /product="prostate androgen-regulated mucin-like protein 1
                     homolog precursor"
                     /protein_id="NP_663537.1"
                     /db_xref="CCDS:CCDS39146.1"
                     /db_xref="GeneID:231440"
                     /db_xref="MGI:MGI:2443349"
                     /translation="MVCKVLIALCIFTAGLRVQGSPTVPLPVSLMTKSSAPVATWTTS
                     APHTARATTPVASATHNASVLRTTAASLTSQLPTDHREEAVTSPPLKRDVNSTDSSPA
                     GFPSTSSDGHLAPTPEEHSLGSPEATVPATGSQSPMLLSSQAPTSATTSPATSLSESL
                     SASVTSSHNSTVANIQPTEAPMAPASPTEEHSSSHTPTSHVTAEPVPKEKSPQDTEPG
                     KVICESETTTPFLIMQEVENALSSGSIAAITVTVIAVVLLVFGGAAYLKIRHSSYGRL
                     LDDHDYGSWGNYNNPLYDDS"
     exon            259..942
                     /gene="Parm1"
                     /gene_synonym="2210012L08Rik; 9130213B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1021
                     /gene="Parm1"
                     /gene_synonym="2210012L08Rik; 9130213B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..2100
                     /gene="Parm1"
                     /gene_synonym="2210012L08Rik; 9130213B05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1175..1180
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Parm1"
                     /gene_synonym="2210012L08Rik; 9130213B05Rik"
                     /note="hexamer: AACAAG"
     polyA_site      1204
                     /gene="Parm1"
                     /gene_synonym="2210012L08Rik; 9130213B05Rik"
                     /note="major polyA site"
     regulatory      1528..1533
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Parm1"
                     /gene_synonym="2210012L08Rik; 9130213B05Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1553
                     /gene="Parm1"
                     /gene_synonym="2210012L08Rik; 9130213B05Rik"
ORIGIN      
        1 gcgccgcagg gcacacagct gactctccgc gccacctcca cttcgccttg cgccgccaga
       61 caccgaagct gcctggactc gtcgcgcctg gcgtccccgc tcctcccgta gcccacccgg
      121 tccgaagagg agctgccggt gccccgaagc acttggtcag acccaggaaa ctcttctcta
      181 gtcgcatcca gctcggtacc gagcaccaga gtaatatggt ctgcaaggtg ctcatcgccc
      241 tctgcatctt caccgcagga ctgagggtac agggttcacc aacagtccca ttgcctgtct
      301 ctctcatgac aaaaagttca gcacctgtgg ccacctggac tacctctgct ccacacactg
      361 ctagggccac cacccctgta gccagtgcca ctcacaacgc ctcagttctc cgcaccactg
      421 ccgcatccct gacatctcag ctccccactg accacagaga agaagctgtc accagcccac
      481 ctttgaagag ggatgtcaac agcacagact cctcacctgc cgggttcccc tcaacaagca
      541 gtgatggcca cttggcaccc acacctgagg aacacagtct tggaagtcct gaagcaactg
      601 tgccagctac tgggtcacag tcacccatgc tcctgtcttc tcaggctcca acctcagcaa
      661 ccacatcccc cgcaacttcc ctatcggagt ctctctctgc ctccgttacc tctagccaca
      721 actctacggt ggccaacatc cagcccacag aagctccaat ggcacctgcg tcaccaacag
      781 aagagcacag ctctagtcac acacccactt cccatgtcac agcagagcca gtgcccaagg
      841 agaaatcacc ccaagacact gaacctggca aagtgatctg tgagtctgag accaccaccc
      901 ccttcctgat catgcaagaa gtggagaatg ccttaagttc aggcagcatc gccgccatca
      961 ccgtgacagt catcgccgta gtgttgctgg tgtttggagg tgcagcatac ctgaagatca
     1021 ggcactcctc ctatggaagg ctgctggacg accatgacta cgggtcctgg gggaactaca
     1081 acaaccctct ctacgatgac tcttaacgaa gaaaggtggc tgaggacaag aagtagcggt
     1141 cctttattta taagtgctta tccagtagaa taataacaag tacctgatgt acactgaacg
     1201 acaatcgcga gccctctttt gttggtatgg ttgtttttgt ttttttttcc cttccccttc
     1261 tctggctgct actacagaat gtctcccttc tgatacaaaa gaaccatctc ggaaaagccg
     1321 ttggtggagg ccggtttgca gctgacacgg gccatctttg cactgaccaa gccagatacc
     1381 atgaggtggg ggctgcagag tccccccgtc atggaagcca ctttggaaag gactgaagga
     1441 aggggctggg agttgcttgg tgggggattt aattttaggg gatcttttgg tttggattat
     1501 ttcttaacgt tcgctacagg aaatgacatt aaatatcagt gaggagaaag gaacgcatcc
     1561 cgggcgactg ccactctgtg tggaaggagc aggggcttct ggattccttt tcaatccttg
     1621 tttgcctggt tgtatctgac aggatgccta cttagtccta taagcagaaa gaccattctg
     1681 agctgcctaa ttgatgaaag ataaaagagg ccgtgcccag gaggagagca gcgggcaagg
     1741 gcaaggtggc acagcaggct gtcaatcagc aggctctcaa cctgctttcc ccatctaggc
     1801 cacccaaagg caacaggaat tcccaaccca caagcaaagc tgggaggtga gcttgaagag
     1861 cagacaggga gagacatgcg gagtctaagg gatgggattg aagagaaaga caaaagctta
     1921 catgcaccac ccactctcct gaagcaagca ggagccagct ctccatggta gtgggagata
     1981 tctaaagctt ggagggaccc atagaactct cgctccacac ctataaagca gcaactgctt
     2041 cactgccttg ctgtttgtat tgggtgatgg ctgtatgcta gtcaaaaaaa aaaaaaaaaa
//
