LOCUS       NM_198410               1689 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus progestin and adipoQ receptor family member VI
            (Paqr6), transcript variant 1, mRNA.
ACCESSION   NM_198410 XM_355445
VERSION     NM_198410.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1689)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1689)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 1689)
  AUTHORS   Tang,Y.T., Hu,T., Arterburn,M., Boyle,B., Bright,J.M., Emtage,P.C.
            and Funk,W.D.
  TITLE     PAQR proteins: a novel membrane receptor family defined by an
            ancient 7-transmembrane pass motif
  JOURNAL   J Mol Evol 61 (3), 372-380 (2005)
   PUBMED   16044242
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK139144.1 and AI607833.1.
            
            On Oct 25, 2007 this sequence version replaced NM_198410.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK139144.1, AY424295.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1669              AK139144.1         2-1670
            1670-1689           AI607833.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..1689
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 38.81 cM"
     gene            1..1689
                     /gene="Paqr6"
                     /gene_synonym="1500001B10Rik"
                     /note="progestin and adipoQ receptor family member VI"
                     /db_xref="GeneID:68957"
                     /db_xref="MGI:MGI:1916207"
     exon            1..35
                     /gene="Paqr6"
                     /gene_synonym="1500001B10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            36..111
                     /gene="Paqr6"
                     /gene_synonym="1500001B10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             61..1092
                     /gene="Paqr6"
                     /gene_synonym="1500001B10Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     progestin and adipoQ receptor family member 6; mPR delta;
                     membrane progesterone receptor delta; membrane
                     progesterone P4 receptor delta; progesterone and adipoQ
                     receptor family member 6; membrane progestin receptor
                     delta"
                     /codon_start=1
                     /product="membrane progestin receptor delta isoform 1"
                     /protein_id="NP_940802.1"
                     /db_xref="CCDS:CCDS17471.1"
                     /db_xref="GeneID:68957"
                     /db_xref="MGI:MGI:1916207"
                     /translation="MLSLKMPQLLRVHQVPRVFWEEGIMSGYRCPTSSALDCVLSSFQ
                     MTNETVNIWTHFLPTWYFLWRLLALGSPGFRADPYHLPLLVFLLPACLYPFASCCAHT
                     FSSMSPRARHICYFLDYGALSLYSLGCAFPYAAYSMPASWLHSRLHQLFVPAAALNSF
                     LCTGLSCYSRFPELEYPGFSKALRTAAFAYPFLFDNLPLFYRLRLCWGGAHSCGRDAL
                     SSNHGYHLLCALLSGFLFAARLPERLAPGRFDYIGHSHQLFHICAVLGTHFQLEAVLA
                     DMGSRRAWLAVQEPTLGLGATVATLSLAVIGNLFIIAAFTASLLRMPGPCPLLQGSPL
                     EEGLQAKQQ"
     exon            112..239
                     /gene="Paqr6"
                     /gene_synonym="1500001B10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            240..442
                     /gene="Paqr6"
                     /gene_synonym="1500001B10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            443..569
                     /gene="Paqr6"
                     /gene_synonym="1500001B10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            570..666
                     /gene="Paqr6"
                     /gene_synonym="1500001B10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            667..817
                     /gene="Paqr6"
                     /gene_synonym="1500001B10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            818..1670
                     /gene="Paqr6"
                     /gene_synonym="1500001B10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1648..1653
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Paqr6"
                     /gene_synonym="1500001B10Rik"
                     /note="putative"
     polyA_site      1669
                     /gene="Paqr6"
                     /gene_synonym="1500001B10Rik"
                     /note="putative"
ORIGIN      
        1 aggcggagcc gaggccaccc ggacgcggca aacaggtcaa cgtggaggta tccggccacc
       61 atgctcagtc tcaagatgcc tcaactcctt cgagtccatc aggtcccccg ggtgttttgg
      121 gaagaaggca tcatgtctgg ctaccgatgc cccacaagct ctgccttaga ctgtgttctc
      181 agctccttcc agatgactaa tgagacggtc aacatctgga ctcacttcct gcccacctgg
      241 tacttcctgt ggcgcctcct ggcgttaggc agcccgggct ttcgcgcgga cccataccac
      301 ctaccgctgc tggtcttcct actgcccgcc tgcctctatc ccttcgcatc ctgctgtgcg
      361 cacaccttta gctccatgtc gcctcgtgct cgtcacatct gctacttcct ggactacggg
      421 gcgctcagcc tctacagcct gggctgcgcc ttcccctatg ccgcctactc catgccggcc
      481 tcctggctgc acagccgcct acaccagctc ttcgtgcccg ctgctgcgct caactctttc
      541 ctgtgcaccg gcctctcctg ctactcgcgg ttcccagagc tagaataccc cgggttcagc
      601 aaggctctcc gcacggctgc ctttgcctac cccttcttgt ttgacaacct cccactgttc
      661 tacaggctgc ggctgtgttg gggcggggcc cacagctgtg ggcgggacgc gctgagctcc
      721 aaccatggtt accacctcct ctgcgctctg ctctcaggct tcctttttgc agcccgtcta
      781 ccagagcgcc tggcacctgg gcgcttcgac tatattggcc acagccacca gctgttccat
      841 atctgtgccg tgctgggcac ccacttccag ctggaagcgg tgctggctga tatgggatcc
      901 cgcagagcct ggctggccgt gcaggagccc accctgggtc tgggggccac tgtagccacc
      961 ttgagcctgg cagtgattgg gaacctgttt atcattgctg ctttcacggc ctccttgctg
     1021 cggatgcctg gaccctgccc cctgctgcag ggtagcccac tggaagaggg actccaagct
     1081 aaacaacagt aaggcccatt ggcatggagg gagggagagg ccaggtctca ctgcctcgga
     1141 agagccctgc ctgacatggg cctgagaagg tggcgactat tctgaccctg aaaggggtag
     1201 ctgaagagaa gaggctctct agggacaggt ggaaggacgg aagacccaag aggcaggtgg
     1261 tgaaggtcta aattaacaca ggtaccaggc ggggagcaga gtggggatgt gaggcctctc
     1321 ctggggcttc tgcccagctg ccccaggacc ttgctcacct caggtcaccc tgagatcttg
     1381 ttccatcggg gccacatacc caccctgccc cagggccaga ctgtgcctct tgtcagcagc
     1441 tctgtatcta ctcactgctg cctgtcttgc tcaccactgt gaccaagcct ttgccaattt
     1501 gtgtgtttgg atgtgtcccc ggtgagataa tggttgtggt ggggattgct gtggggaggt
     1561 aggctatggg actttaggaa ggaaagtttt cttgtttgtt tgtttttgtt gttgtttttg
     1621 tttttgctat ccatcacaaa gcagtataat aaagaagcaa atgaactgga aaaaaaaaaa
     1681 aaaaaaaaa
//
