LOCUS       NM_172555               3776 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus poly(A) polymerase gamma (Papolg), mRNA.
ACCESSION   NM_172555
VERSION     NM_172555.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3776)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3776)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ075859.1, AK035810.1, DQ103505.1 and BC023030.1.
            
            On Apr 10, 2009 this sequence version replaced NM_172555.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC059271.1, AK035810.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                CJ075859.1         2-18
            18-1321             AK035810.1         1-1304
            1322-2454           DQ103505.1         1128-2260
            2455-3776           BC023030.1         792-2113
FEATURES             Location/Qualifiers
     source          1..3776
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 14.37 cM"
     gene            1..3776
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /note="poly(A) polymerase gamma"
                     /db_xref="GeneID:216578"
                     /db_xref="MGI:MGI:2442119"
     exon            1..249
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             233..2452
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /EC_number="2.7.7.19"
                     /note="SRP 3'-adenylating protein; PAP-gamma; SRP RNA
                     3'-adenylating enzyme; polynucleotide adenylyltransferase
                     gamma; SRP RNA-adenylating enzyme; signal recognition
                     particle RNA-adenylating enzyme"
                     /codon_start=1
                     /product="poly(A) polymerase gamma"
                     /protein_id="NP_766143.2"
                     /db_xref="CCDS:CCDS24481.1"
                     /db_xref="GeneID:216578"
                     /db_xref="MGI:MGI:2442119"
                     /translation="MKEMSANTMLDSQRQQKHYGITSPISLACPKEIDHIYTQKLIDA
                     MKPFGVFEDEEELNHRLVVLGKLNNLVKEWISDISESKNLPPSVVATVGGKIFTFGSY
                     RLGVHTKGADIDALCVAPRHVERSDFFQSFFEKLKHQDGIRNLRAVEDAFVPVIKFEF
                     DGIEIDLVFARLAIQTISDNLDLRDDSRLRSLDIRCIRSLNGCRVTDEILHLVPNKET
                     FRLTLRAVKLWAKRRGIYSNMLGFLGGVSWAMLVARTCQLYPNAAASTLVHKFFLVFS
                     KWEWPNPVLLKQPEESNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSTSTRT
                     VMVEEFKQGLAVTDEILQGKSDWSKLLEPPNFFQKYRHYIVLTASASTEENHLEWVGL
                     VESKIRVLVGNLERNEFITLAHVNPQSFPGNKEHHKANNYVSMWFLGIIFRRVENAES
                     VNIDLTYDIQSFTDTVYRQANNINMLKDGMKIEATHVKKKQLHHYLPAEILQKKKKSL
                     SDVSRSSGGLQSKRSSLDSTCLDSSRDTDSGTPFNSPVSANKPSNPDSPTGEIERSSA
                     EPVAVVVEKLPSVPPAQGLSIPVIGAKVDPTAKAVSSPAVCTIPTVVGRNVIPRITTP
                     HNPVQGQPHLNGISNITKNVTPKRSHSPPTDGTSKRLKDIEKFIRLESAFKESRAAED
                     RKRKPMDSIGGESMPIPTIDTARKKRLPSKELPDSSSPVPANNIRVIKNSIRLTLNR"
     exon            250..411
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            412..478
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            479..560
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            561..670
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            671..724
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            725..836
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            837..926
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1065
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1138
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1259
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1260..1344
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1398
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1399..1518
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1628
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1629..1750
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1751..1920
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1921..2009
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2010..2230
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2231..2296
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2297..2353
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2354..3764
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      3764
                     /gene="Papolg"
                     /gene_synonym="9630006B20Rik"
                     /note="major polyA site"
ORIGIN      
        1 aggcgagagg cagcctggga agtagcgcca tattggcggt ggccgcgctg tattgtcata
       61 aatagagccg gttttgtggt gttttcacta ctcggttgaa tgcctcggct gtagagagtg
      121 gggaagtgag cgagctacaa gcgagcgaag ggaattggac agaggaagga agagagggca
      181 agaacaggac cccaaagcga aagacactcg ctggagagag acgcaggaag cgatgaaaga
      241 gatgtctgca aacactatgc tggacagcca gcgtcaacag aagcattatg gaattacctc
      301 tccaattagt ttggcatgtc ctaaagaaat tgatcatatt tatacacaga agttaattga
      361 tgccatgaag ccatttggag tatttgaaga tgaggaagaa ttgaaccaca ggctggttgt
      421 tcttggtaaa ttgaacaatt tagtaaaaga atggatttct gacatcagtg aaagtaagaa
      481 tctcccacct tctgttgtgg ctactgttgg tggtaaaatt ttcacatttg gatcttacag
      541 gcttggagta cacaccaaag gagctgatat tgatgcactt tgtgttgccc caagacatgt
      601 agagagatca gatttttttc agtccttttt tgaaaaattg aaacatcaag atggcattag
      661 aaacttaaga gctgtagaag atgcttttgt acctgttata aaatttgaat ttgatggtat
      721 tgaaattgat ctagtctttg caagactggc aatacaaacc atatcagata atttagacct
      781 aagagatgac tctcgcctga gaagccttga tatacggtgc attagaagtt taaatggatg
      841 tagagttact gatgaaattt tgcacttagt gccaaataaa gaaactttta gactcaccct
      901 aagagcagtc aaattatggg caaagcgccg tggtatttat tccaatatgc tgggattcct
      961 tggtggtgtc tcctgggcaa tgctagttgc cagaacttgc caactgtacc caaatgcagc
     1021 agcttcaact ttagttcaca agtttttttt agttttttcc aaatgggaat ggccaaatcc
     1081 tgtgctgttg aagcaaccag aagaaagcaa cttgaacttg cctgtctggg atcctcgggt
     1141 aaatccgtca gacaggtatc atcttatgcc aataattacc cctgcctacc cacaacagaa
     1201 ttctacatat aatgtgtcta catcaactcg aacagtaatg gtagaagaat ttaaacaagg
     1261 tcttgcagtt acagatgaaa ttcttcaagg gaaatcagat tggtccaaac tattagagcc
     1321 accaaatttc tttcaaaaat acagacatta tatagtactg actgccagtg catcaacaga
     1381 agagaaccat ctagaatggg ttggattagt agaatctaaa atccgtgtac ttgttggaaa
     1441 cttggaacgg aatgaattta ttactcttgc ccatgtgaat ccccagtcat tcccaggaaa
     1501 taaagaacat cataaagcca acaattacgt atcaatgtgg ttccttggga taatttttcg
     1561 gagagtagaa aatgcagaaa gtgttaacat agacttgaca tatgatatcc agtcatttac
     1621 tgatacagtg tacaggcagg caaacaatat aaatatgctg aaggatggga tgaaaattga
     1681 agcaactcat gtaaagaaaa agcagcttca tcattaccta ccagcagaga ttcttcaaaa
     1741 gaagaaaaag agtctttctg atgtaagtcg gagttcaggg ggccttcagt ccaaaagatc
     1801 atctctggat agcacttgtc tggatagctc cagagacact gacagtggaa caccttttaa
     1861 ctctccggtg tctgcaaata agccttccaa cccagacagc cccacaggag aaatagaaag
     1921 gagtagtgct gagcctgtgg ctgtggttgt ggagaagctg ccaagtgtcc ccccagctca
     1981 ggggctgtcc attccagtca ttggtgcaaa ggttgaccct acagcaaaag ctgtatcctc
     2041 cccagctgtg tgcaccattc ctactgtagt aggacggaat gttattccta gaatcacaac
     2101 accccacaac cctgtccagg gacaaccaca tctaaatggg atatcaaata ttactaagaa
     2161 tgttacaccc aaaagatccc attcgccacc tacagatggg acttctaaga ggctgaaaga
     2221 catagaaaag ttcattcgac ttgagtcagc atttaaggag tcccgggctg ccgaggatcg
     2281 gaaaagaaaa ccaatggatt cgattggtgg agaatctatg cctattccaa ctattgatac
     2341 ggcacgcaaa aagagactac ccagtaaaga actcccagat tcatcatctc cagttccagc
     2401 aaacaacatc cgtgtcatca aaaactcgat ccgcctgacc cttaatcggt aatagcagtg
     2461 cctcttcact taggtgagca tgcgtcatgc agtgcatcga tggcagccag tcttcaaagt
     2521 agaaccagct gccatacaga taggtgacag ggacagtcgt cagcctaatg acctaggagt
     2581 ggtttttgaa ctctcacact ggaaccctga gatgacgtag cagtctctca ctggttgccg
     2641 agtccactct gaggatacct gccagtaaat gtcacctaca gtgttatggc tttgcatttt
     2701 gaggttttac tgccttaact ttggatgttt gttgtttctc tgttatggga accagttctt
     2761 ggtcacttgg actctgataa aaacaagtcc tgaactgttt tgtttggttt tttttttttt
     2821 tgttttttgt ttttagtgtt atgttgtaat cattgtatag agctgaaaaa gttaaaaaac
     2881 aaacaaaaaa aagcccttct cttgtaattt tccaaatgtt tatgtgttta ctttagcatt
     2941 gaagccactt tgtgaaacct gagattaatg aatgtgagat atcttttctg cttccttcat
     3001 ttgtgtagat atctattttg tttatttaaa ttattttttc caaactggca catgaatatt
     3061 taaactattt tttgtgcttt tgtccaaatg ttgcgtagtt accaaggagg attagtccag
     3121 tgactgacta cacaagagtt gggcaccata aatgttttgc ctcccatgga ggccttcaaa
     3181 atgcatcttt attaaaaatc aaactataac caggatactg aaagtcagta tatgaatggt
     3241 gaaattgtta catatcttac tatctcatgg cattcttgtt agctgattgg tattttttac
     3301 agaggaagaa ttcattctgc catcaatgat aagatccctt taagtatagc agacttgtat
     3361 ttttgaagta taaaagtaac tcagcatggt aattgctcac cataactccc cacagtcgcc
     3421 aacagtttct tcatggatta ggcatgcaga aataagcagt ggattttatt gaaacctcaa
     3481 ggcatttctg aatgacattg ttaccaacca ttaattggct caggaccttt gtagttttta
     3541 tttaactata tgagttgtct ttttttacac tgcttttttc agtgcatttc ttaatatttt
     3601 ttaagtttca tgaatgcatg ctcagtttat gaaaaatcca caaccatgta attcttgtaa
     3661 tctgttgact ccgtgttttg taaatgaagc cgtatgtatt ttcagagtat ttttgtatgt
     3721 actgtaagat atcatctttt caaagagaaa ctttaaaacc tttaaaaaaa aaaaaa
//
