LOCUS       NM_028291               5052 bp    mRNA    linear   ROD 12-MAR-2023
DEFINITION  Mus musculus PAN3 poly(A) specific ribonuclease subunit (Pan3),
            transcript variant 1, mRNA.
ACCESSION   NM_028291 XM_485702
VERSION     NM_028291.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5052)
  AUTHORS   Zhang CL, Long TY, Bi SS, Sheikh SA and Li F.
  TITLE     CircPAN3 ameliorates myocardial ischaemia/reperfusion injury by
            targeting miR-421/Pink1 axis-mediated autophagy suppression
  JOURNAL   Lab Invest 101 (1), 89-103 (2021)
   PUBMED   32929177
  REMARK    GeneRIF: CircPAN3 ameliorates myocardial ischaemia/reperfusion
            injury by targeting miR-421/Pink1 axis-mediated autophagy
            suppression.
            Erratum:[Lab Invest. 2021 Jan 22;:. PMID: 33483599]
REFERENCE   2  (bases 1 to 5052)
  AUTHORS   Cai Y, Yoneda M, Tomita T, Kurotani R, Okamoto M, Kido T, Abe H,
            Mitzner W, Guha A and Kimura S.
  TITLE     Transgenically-expressed secretoglobin 3A2 accelerates resolution
            of bleomycin-induced pulmonary fibrosis in mice
  JOURNAL   BMC Pulm Med 15, 72 (2015)
   PUBMED   26178733
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5052)
  AUTHORS   Zheng D, Ezzeddine N, Chen CY, Zhu W, He X and Shyu AB.
  TITLE     Deadenylation is prerequisite for P-body formation and mRNA decay
            in mammalian cells
  JOURNAL   J Cell Biol 182 (1), 89-101 (2008)
   PUBMED   18625844
REFERENCE   4  (bases 1 to 5052)
  AUTHORS   Siddiqui N, Mangus DA, Chang TC, Palermino JM, Shyu AB and Gehring
            K.
  TITLE     Poly(A) nuclease interacts with the C-terminal domain of
            polyadenylate-binding protein domain from poly(A)-binding protein
  JOURNAL   J Biol Chem 282 (34), 25067-25075 (2007)
   PUBMED   17595167
  REMARK    GeneRIF: the poly(A) nuclease interacts with the C-terminal domain
            of polyadenylate-binding protein domain from poly(A)-binding
            protein
REFERENCE   5  (bases 1 to 5052)
  AUTHORS   Nishimura M, Yokoi N, Miki T, Horikawa Y, Yoshioka H, Takeda J,
            Ohara O and Seino S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   6  (bases 1 to 5052)
  AUTHORS   Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng
            EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC,
            Babbitt PC and Ferrin TE.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 5052)
  AUTHORS   Mu X, Zhao S, Pershad R, Hsieh TF, Scarpa A, Wang SW, White RA,
            Beremand PD, Thomas TL, Gan L and Klein WH.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
REFERENCE   8  (bases 1 to 5052)
  AUTHORS   Piao Y, Ko NT, Lim MK and Ko MS.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134441.4 and AC131730.2.
            
            [WARNING] On Apr 18, 2023 this sequence was replaced by
            NM_028291.6.
            
            On Jan 4, 2018 this sequence version replaced NM_028291.4.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            CCDS Note: The coding region has been updated to extend the
            N-terminus to one that is supported by available conservation data.
            The upstream in-frame AUG is conserved in all mammals with
            available genomic sequences in this region. and results in a
            146aa-longer protein, but the splice sites are unaffected.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-854               AC134441.4         81436-82289         c
            855-976             AC134441.4         61671-61792         c
            977-1043            AC134441.4         59127-59193         c
            1044-1114           AC134441.4         57257-57327         c
            1115-1262           AC134441.4         24187-24334         c
            1263-1510           AC131730.2         177078-177325       c
            1511-1615           AC131730.2         174896-175000       c
            1616-1673           AC131730.2         173597-173654       c
            1674-1835           AC131730.2         170150-170311       c
            1836-1952           AC131730.2         169789-169905       c
            1953-2054           AC131730.2         169600-169701       c
            2055-2220           AC131730.2         166710-166875       c
            2221-2311           AC131730.2         165523-165613       c
            2312-2451           AC131730.2         160290-160429       c
            2452-2581           AC131730.2         157458-157587       c
            2582-2646           AC131730.2         157024-157088       c
            2647-2785           AC131730.2         153622-153760       c
            2786-2915           AC131730.2         151095-151224       c
            2916-5052           AC131730.2         148329-150465       c
FEATURES             Location/Qualifiers
     source          1..5052
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5"
     gene            1..5052
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /note="PAN3 poly(A) specific ribonuclease subunit"
                     /db_xref="GeneID:72587"
                     /db_xref="MGI:MGI:1919837"
     exon            1..854
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            855..976
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1043
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1114
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1115..1262
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1510
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1511..1615
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..1673
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1674..1835
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1836..1952
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1953..2054
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2055..2220
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2221..2311
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2312..2451
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2452..2581
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2582..2646
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2647..2785
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2786..2915
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2916..5052
                     /gene="Pan3"
                     /gene_synonym="2700050F09Rik; A430027N15Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgccactcg cgcaggcgca gaggcggcga gcgtctcagg aagaggaaaa tggcataaac
       61 aagtcgggag gacccggagc gcgagccgac gagcgagcgg agggcaagag tttaaaaaca
      121 aaccggcggc tccctcccgc cgtgcctttg ccccacagct tccggtcgcc gccgcctcag
      181 ggtcgtttct ccccgcagcc ccggccgcgc gcccaccgcg gcgtcccgcg cggccccttt
      241 aaggacagcg gagagggaga gggagaatcc ctgctcgccg cccgcccgcc cttccccctc
      301 cccgggcggc tccggctccc tcagcggggc ccaacccgcc cgcccggctt ccatccggct
      361 ccggcggcgg ctccttcccg ccctcgtcta tggtggcggc gggggacgcg gctgcggcgt
      421 ggccatgaac agtggcggcg gcggtggcct cccgccgccc tcggccgctg cctcgccgtc
      481 gtcgtcctcg ctggcggcgg ccgtggcggt ggcggtggcg gcctcgtcgg gcgtcggggg
      541 cgtccccggc gggccggcgg cggcggcggg cgtgaagctc aagtactgcc gctactacgc
      601 caaggacaag acgtgcttct acggcgagga gtgtcagttc ctgcacgagg acccagccgc
      661 cggcgcggcc ccggggcttg gcctccatag caacagcgtc ccgctggcgc tagcggccgc
      721 ggccggggcc gcctttcctc cgggagcgct cccgggcggg ggagcggggc cgcccgcggg
      781 gcccaagaag ccggagctgg gcgtcccggg ggcggcgacc gcgggcggcg gactcgatgg
      841 cccgcgggtg gcgattccgg gaatggatgg aggtgcttta actgatgcga gtctcacaga
      901 gtcctatttc agcaccagct ttattggagt caatggattt ggaagccctg tagaaacaaa
      961 gtatcccttg atgcagagaa tgactagtag tagcagctcc ccaagccttc taaatgacag
     1021 tgccaagcca tacacaggcc acgatcttct gacttcatct gcttcatcct tgtttaatga
     1081 cttcggtgcc ctcaacatct cccagagaag gaagacacca aatcctactg caagcgaatt
     1141 tatacctaaa ggaggatcaa cctccaggct gagtaacgtg tcccagtcaa atatgtctgc
     1201 cttctctcaa gttttctctc acccatccat gggaagtcct gctactgctg gattagcacc
     1261 aggaatgtca ctgtctgctg gatcttcccc tctccattcc cccaaaatta ctccacacac
     1321 ctctcctgct cctagaagaa gaagccacac tccaaaccca gcaagtttca tggtgccgcc
     1381 tagtgcctcc actcctgcca ataaccctgc tcctcagcct ccgtcctctg gtcaggtgat
     1441 ccagaaggag actgtcgggg ggacgactta cttctataca gatacaaccc cagcaccttt
     1501 gactggaatg gtatttccaa actatcatat ttatcctcca accgcacctc atgttgctta
     1561 tatgcaacca aaagcaaatg caccttcctt cttcatggcc gacgagctcc gacaggagct
     1621 gatcaacaga catttaataa cgatggctca aattgaccaa gcagatatgc cagcagtccc
     1681 cacagaagtt gacagctacc atagcctgtt ccctctagaa ccactgccac ctcccaaccg
     1741 gatacagaaa tcaagtaatt ttggatatat cacgtcttgc tacaaagctg taaatagcaa
     1801 agatgatctg ccatattgcc ttcggaggat acatggtttt cgtcttgtta acacaaagtg
     1861 catggtgttg gttgatatgt ggaaaaaaat tcagcactca aatattgtaa ctctgcgtga
     1921 agtgtttacc actaaagcat ttgccgagcc ttctctggtg ttcgcctatg atttccatgc
     1981 tggaggagaa actatgatga gcagacactt taacgacccg aattctgatg cctacttcac
     2041 aaagaggaag tggggccagc acgatggacc actgcccagg cagcatgctg gattgttacc
     2101 agagtctctc atctgggcat acattgtaca gctgagttct gctctgcgga ccattcatac
     2161 agcaggtttg gcctgtagag taatggaccc aacgaagatt ctgataacca gcaaaacaag
     2221 gttacgagta aattgtgtag gagtctttga tgttttaaca tttgataaca gtcaaaataa
     2281 taatcctttg gcattaatgg ctcagtacca gcaagcagat ctgatatcat taggaaaagt
     2341 tgtgttggct ttggcttgca actctttggc aggaattcag cgagaaaatt tacagaaagc
     2401 catggaattg gtgacaatca actactcctc tgacctgaag aacctcatct tgtacttgtt
     2461 gactgaccaa aacaggatgc ggagtgtgaa tgacatcatg cccatgattg gtgctcggtt
     2521 ttacactcaa ttggatgctg ctcaaatgag aaatgatgtt atcgaggaag accttgctaa
     2581 ggaggttcaa aatggaagac tgtttaggct tctagcaaaa ttgggaacaa tcaacgagag
     2641 gccggagttt cagaaggatc caacctggtc agagactgga gacagatacc tgttgaaact
     2701 ctttagagat catctttttc atcaggtgac agaagcaggt gctccctgga tcgacctcag
     2761 tcacatcatt tcttgtctta acaagctaga tgctggtgtg ccagaaaaaa tcagcctgat
     2821 ttccagagac gagaagagcg tgctggtggt gacatacagt gacctaaaac gctgctttga
     2881 aaataccttt caagaactga ttgcggctgc aaatggtaac gatcggaaca gtaactgaag
     2941 gagcaggcgc tgctcttctc caggttcatc tagaggcttc ttcaaagagg cgtctgtctg
     3001 ccagtcacat acacttatct tgacgtaatt tttaatagca aaatgaaatt gtgctgaagg
     3061 cctaaaagtg gaggagttat attaccttag ggtctttcca gtttatttgt tttttgtttt
     3121 tttttttgtt tttgtttttt gttttttgtc tttgaactac agctttataa tggtacttta
     3181 cactggatag actcagacac tgtcgaggag gtgagctgag cacagcagtg gcctgatgct
     3241 ttgcggcctg actctggagg gacacttttc tgctgtgcct ttgcactcac tgcttaaccc
     3301 aaaggaacag gacttttgat aaaactcacc ctgtagggtc ggtcatctga gaaggccatt
     3361 tcaaaagttg gagttttcct ccatggaact tactatttgg acatgcagtt gtcgccaaac
     3421 tcaagtattg tgggatttgt ggtcacttcg atactgaaga ctgccaaata cattgggatt
     3481 ttctcttaaa cagccgccat gaagacttca tctccttccc ggtgctgtgt gttgagcgcg
     3541 cactgggtgt gcaccccata cctgggaaga aatgtgggga tttggaggtc aggacagact
     3601 ccaagcactt gcaactgatg ttactgtctt catttttaac aagtatgcgt atttgtatat
     3661 ttcagagaag tttttaacat ttctctgtcc actttttata agctttaaaa tgatttttct
     3721 ctgccttgaa atttgcatca agaaaaagca cctctcttca ctgaaagctt tgaggactag
     3781 agacacactt cccatgtcta acaagcacgt ctgtatctga gagcgctagc atcagttgtt
     3841 aatgagaaaa tcaattactg catttgatct ggatggattt tagaagaaca taatgttcaa
     3901 tattccaagg ataatgaaca tttgccacca tgatgttcct tgtgtttaaa gggaacgaga
     3961 actttcggtg taccacgcag aagtctttat cattagctca tgtatttgag gaagagcagc
     4021 tgtcttttta tatgtttttt gacaaatcat attgtaattc ttttgtacaa aaaagaacta
     4081 cttgtattct agaagaaata tgaaatgctt aatttataag cgggctggag atttttttcc
     4141 aatattgttt tctttgaaaa tgaaagggga tcatctattt tagttttggg ggcctgggaa
     4201 ctttttgaaa attttcattt gtggaccaat gttatgtgaa tgctaaggaa gggcaggggt
     4261 aacatagggc ttggacctct agtcctgcat agaccagcaa actcccctct gcaaggcagg
     4321 ttcacatcac aaccccgagt gtctgcatca gaaatgctag tctgcttccg ccccagcaac
     4381 ctcaggactt gggttgggta taaaaggtag tcagctgaaa gtacctaagt aaatagtgtc
     4441 agccagaaaa cagtcggtgt caggtgatac gtatttttta gctttgtttt atatttattt
     4501 ttcatttcat tttcattggg aatggttttc aaaagaactc ttgagttctg ctttgatggg
     4561 tttctttttt ttttttttct gttttgtttt gctttgcttt tttttttttt tttttttttt
     4621 tctgggagcc ctcttttcca cagtgtaaac ccatatagaa ggttgtctga aagttactat
     4681 ttagtgcata ggaagagttt aatatctgag agtatcgaat gaaggatgtg aactcatcat
     4741 aacttcctgt tatgacagac acaacacgga aaggacaacc cttgaaatca tgtcgcgtcg
     4801 ctcacttcag cagtgtaccc atctccagtc ctgttagtgt attcacttca ctgcagatac
     4861 ctttgagggt gcccttgtgt tctgctttga ccttggttct gtcattggat agcaacattg
     4921 tctctagaaa gcaccagtac gtttaagttc taatgtcaca atcccagtac ctgttgctca
     4981 tctttaaccc tgttttcagt ctctacgtgt atagcagtat tttttaataa agaattgcag
     5041 aaataaactt gt
//
