LOCUS       NM_023245               2414 bp    mRNA    linear   ROD 07-MAY-2024
DEFINITION  Mus musculus palmdelphin (Palmd), mRNA.
ACCESSION   NM_023245 XM_911261
VERSION     NM_023245.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2414)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2414)
  AUTHORS   Ahuja,N., Hiltabidle,M.S., Rajasekhar,H., Voss,S., Lu,S.Z.,
            Barlow,H.R., Cowdin,M.A., Daniel,E., Vaddaraju,V., Anandakumar,T.,
            Black,E., Cleaver,O. and Maynard,C.
  TITLE     Endothelial Cyp26b1 restrains murine heart valve growth during
            development
  JOURNAL   Dev Biol 486, 81-95 (2022)
   PUBMED   35364055
REFERENCE   3  (bases 1 to 2414)
  AUTHORS   Sainz-Jaspeado,M., Smith,R.O., Plunde,O., Pawelzik,S.C., Jin,Y.,
            Nordling,S., Ding,Y., Aspenstrom,P., Hedlund,M., Bastianello,G.,
            Ascione,F., Li,Q., Demir,C.S., Fernando,D., Daniel,G.,
            Franco-Cereceda,A., Kroon,J., Foiani,M., Petrova,T.V.,
            Kilimann,M.W., Back,M. and Claesson-Welsh,L.
  TITLE     Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in
            the Endothelium
  JOURNAL   Circulation 144 (20), 1629-1645 (2021)
   PUBMED   34636652
  REMARK    GeneRIF: Palmdelphin Regulates Nuclear Resilience to Mechanical
            Stress in the Endothelium.
REFERENCE   4  (bases 1 to 2414)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2414)
  AUTHORS   Nie,Y., Chen,H., Guo,C., Yuan,Z., Zhou,X., Zhang,Y., Zhang,X.,
            Mo,D. and Chen,Y.
  TITLE     Palmdelphin promotes myoblast differentiation and muscle
            regeneration
  JOURNAL   Sci Rep 7, 41608 (2017)
   PUBMED   28148961
  REMARK    GeneRIF: the results presented here demonstrate that cytosolic
            protein Palmd can promote myoblast differentiation, and is required
            for optimal muscle regeneration after CTX injection.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2414)
  AUTHORS   Lord-Grignon,J., Abdouh,M. and Bernier,G.
  TITLE     Identification of genes expressed in retinal progenitor/stem cell
            colonies isolated from the ocular ciliary body of adult mice
  JOURNAL   Gene Expr Patterns 6 (8), 992-999 (2006)
   PUBMED   16765103
REFERENCE   7  (bases 1 to 2414)
  AUTHORS   Hu,B., Petrasch-Parwez,E., Laue,M.M. and Kilimann,M.W.
  TITLE     Molecular characterization and immunohistochemical localization of
            palmdelphin, a cytosolic isoform of the paralemmin protein family
            implicated in membrane dynamics
  JOURNAL   Eur J Cell Biol 84 (11), 853-866 (2005)
   PUBMED   16323283
REFERENCE   8  (bases 1 to 2414)
  AUTHORS   Castellini,M., Wolf,L.V., Chauhan,B.K., Galileo,D.S.,
            Kilimann,M.W., Cvekl,A. and Duncan,M.K.
  TITLE     Palm is expressed in both developing and adult mouse lens and
            retina
  JOURNAL   BMC Ophthalmol 5, 14 (2005)
   PUBMED   15969763
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 2414)
  AUTHORS   Andreu,N., Escarceller,M., Feather,S., Devriendt,K., Wolf,A.S.,
            Estivill,X. and Sumoy,L.
  TITLE     PALML, a novel paralemmin-related gene mapping on human chromosome
            1p21
  JOURNAL   Gene 278 (1-2), 33-40 (2001)
   PUBMED   11707320
REFERENCE   10 (bases 1 to 2414)
  AUTHORS   Hu,B., Copeland,N.G., Gilbert,D.J., Jenkins,N.A. and Kilimann,M.W.
  TITLE     The paralemmin protein family: identification of paralemmin-2, an
            isoform differentially spliced to AKAP2/AKAP-KL, and of
            palmdelphin, a more distant cytosolic relative
  JOURNAL   Biochem Biophys Res Commun 285 (5), 1369-1376 (2001)
   PUBMED   11478809
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY123980.1, AK014531.1, AK136939.1 and AF263246.1.
            
            On Mar 10, 2006 this sequence version replaced NM_023245.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014531.1, BC010193.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-203               BY123980.1         27-229
            204-840             AK014531.1         2-638
            841-2022            AK136939.1         748-1929
            2023-2388           AK014531.1         1821-2186
            2389-2394           AF263246.1         2093-2098
            2395-2414           AF263246.1         2105-2124
FEATURES             Location/Qualifiers
     source          1..2414
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 50.49 cM"
     gene            1..2414
                     /gene="Palmd"
                     /gene_synonym="4631423C22Rik; PALML"
                     /note="palmdelphin"
                     /db_xref="GeneID:114301"
                     /db_xref="MGI:MGI:2148896"
     exon            1..455
                     /gene="Palmd"
                     /gene_synonym="4631423C22Rik; PALML"
                     /inference="alignment:Splign:2.1.0"
     CDS             411..2066
                     /gene="Palmd"
                     /gene_synonym="4631423C22Rik; PALML"
                     /note="paralemmin-related"
                     /codon_start=1
                     /product="palmdelphin"
                     /protein_id="NP_075734.3"
                     /db_xref="CCDS:CCDS17793.1"
                     /db_xref="GeneID:114301"
                     /db_xref="MGI:MGI:2148896"
                     /translation="MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEEKLKHQHLKKK
                     ALREKWLLDGIGSGKEHEEMKKQNQQDQHQTQVLEQSILRLEKEIQDLEKAELQISAN
                     EEAILKKLKSIEKTTEDIIRSVKVEKEENPEESIEDIYANIPDLPSSYIPSRLRKERN
                     EGPDDEQNRKALYAMEIKVEKDLKTGESVVLSSIPLPSDDFKSTGIKVYEDRQKSVYA
                     VSSNQNTTYNGTDGLAPVEVEDLLRQASERNSKSPTEYHEPVYANPFCRPVTPQRERV
                     ISPGPNFQERIMMKTNGLGNHANESAHNMTDGLSERRSNGPTHTSPTRPTPQPRSMVQ
                     QVEEMVHTQQKRMASPWEESSNRQNEHEVSPRMELSPSRASPGKSGPQCSSPTCQEET
                     EDVRYNIVHSLPSDVDDTEPVTMIFMGYQQADDNEEEKKLLTGYDGVIHAELVVIDDE
                     AEDNEGQTERPSYHPVAPYSQVYQPPKPTPLPRKRAEVRPYENTNHKSPHKNSISLKE
                     QEERLGSPARHSPLDVPVAGDGTEDPSLTALRIRMAKLGKKVI"
     exon            456..536
                     /gene="Palmd"
                     /gene_synonym="4631423C22Rik; PALML"
                     /inference="alignment:Splign:2.1.0"
     exon            537..661
                     /gene="Palmd"
                     /gene_synonym="4631423C22Rik; PALML"
                     /inference="alignment:Splign:2.1.0"
     exon            662..776
                     /gene="Palmd"
                     /gene_synonym="4631423C22Rik; PALML"
                     /inference="alignment:Splign:2.1.0"
     exon            777..810
                     /gene="Palmd"
                     /gene_synonym="4631423C22Rik; PALML"
                     /inference="alignment:Splign:2.1.0"
     exon            811..921
                     /gene="Palmd"
                     /gene_synonym="4631423C22Rik; PALML"
                     /inference="alignment:Splign:2.1.0"
     exon            922..2022
                     /gene="Palmd"
                     /gene_synonym="4631423C22Rik; PALML"
                     /inference="alignment:Splign:2.1.0"
     exon            2023..2394
                     /gene="Palmd"
                     /gene_synonym="4631423C22Rik; PALML"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2367..2372
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Palmd"
                     /gene_synonym="4631423C22Rik; PALML"
                     /note="hexamer: AATAAA"
     polyA_site      2391
                     /gene="Palmd"
                     /gene_synonym="4631423C22Rik; PALML"
                     /note="major polyA site"
ORIGIN      
        1 cacggcagct ccctgcgcca ctcctggaaa ataatgactt gggtaaggaa cagttaataa
       61 gaaaatgtgt ctcgctaacc gtgcacagca caacaaagag ctggcagccc ctgaaggaaa
      121 agggcttgtg cggctgccgt tcaaacttgt cagtcaactc gtgccagcag cctcagcgtc
      181 tgcctcccca gtgcaccctc attacatgtg tctgtctggc ctcatctgtg catgggctct
      241 gagccgctcc gctcctgaca gttcggaatt ctcttcctct ctccctgctg caaagagcgg
      301 atttctctcc gtgtctcttc tgtcatctcc agctcccctc tccaaggacg caccttgatt
      361 tatggtagct ttggacttcc ttcagcgtct gcctgtcctt gacttctaga atggaagaag
      421 ctgagctggt gaagggaaga ctccaggcca tcactgacaa aagaaagata caggaagaaa
      481 tctcacagaa gcgtctgaaa atagaggaag aaaaattgaa acaccaacat ctgaagaaaa
      541 aagccctgag ggagaaatgg ctcctggatg gaatcggcag tggaaaagaa cacgaagaga
      601 tgaagaagca aaatcagcaa gaccagcacc agacccaggt tctagagcaa agcatcctca
      661 ggcttgagaa agagatccaa gatcttgaaa aggctgaact gcaaatctca gccaacgaag
      721 aggcaattct gaagaagcta aagtcgatcg agaagaccac agaagacata ataagatccg
      781 tgaaggtgga aaaggaagaa aacccagaag agtcaatcga ggacatctat gctaatatcc
      841 ctgaccttcc aagttcctac ataccttccc gattaagaaa ggaaagaaac gaaggaccag
      901 atgacgaaca aaacagaaaa gctttgtatg ccatggaaat taaagttgaa aaagatttga
      961 agactggaga gagcgtagtt ctgtcttcaa taccgctgcc atctgatgac tttaaaagca
     1021 cagggataaa agtgtatgag gaccggcaga aatcagtcta tgctgttagc tccaatcaga
     1081 acacaaccta caatggcacc gacggcctcg cacctgtcga agtggaggat ctcctaagac
     1141 aagcctcaga gaggaactct aaatcgccca cagagtacca tgagccagtg tacgccaatc
     1201 cgttttgcag gcctgtgacc ccacagagag aaagagtcat aagccctgga ccaaattttc
     1261 aagaaaggat aatgatgaaa acgaacggac tgggcaacca tgcaaatgaa tctgcgcaca
     1321 atatgaccga cgggctctca gagaggagaa gcaacggtcc cactcacacc agtcccactc
     1381 ggccaacacc tcagccccga tcaatggttc agcaagtgga agagatggtc cacacccaac
     1441 aaaagaggat ggcaagccct tgggaagaat ccagcaacag gcaaaacgaa cacgaagttt
     1501 ctccaaggat ggaactgagc cccagcagag caagccctgg gaaatcggga ccccagtgtt
     1561 cttcacccac ttgccaggag gagacagaag atgtcagata taacatcgtt cattccctgc
     1621 cttctgatgt ggatgacaca gaacctgtaa caatgatttt catggggtat cagcaggcag
     1681 atgataatga ggaagaaaag aagcttttga caggctacga cggggtcatc cacgctgagc
     1741 tcgttgtgat tgatgacgag gcggaggata atgaaggaca aaccgagagg ccatcctacc
     1801 atcccgtagc tccctacagt caggtttacc agccacccaa accaacccca cttcctagaa
     1861 agagagcgga agttaggccg tatgaaaaca caaaccataa atctcctcac aaaaattcca
     1921 tctctctgaa agagcaagag gaacgcttag gcagccctgc ccggcactct cccctggatg
     1981 tcccagtagc tggagacggg actgaggatc cttccttaac agctttaaga ataagaatgg
     2041 ccaagctggg gaaaaaggtg atctgagagc cgtggtgccc acctgaataa cctctgaagg
     2101 agaagccacg aaatgcctga aaacttctct tctgaattct tttatttctt gtccctaaag
     2161 tccaaaacta tataattata cccatagtaa gtcacataaa taaatattag tcattattta
     2221 ggggggaatc ccccctcaaa aaaaactggg acaacaaatg ctaacttttc cagttacttg
     2281 atatgactca gtggggccgg gggaaccagt atatttttat tgtattgata ccaaagcatt
     2341 tctaataaga gcttgttgaa tttaagaata aagttattta aaataccttg actaaaaaaa
     2401 aaaaaaaaaa aaaa
//
