LOCUS       XM_030251248            9065 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus p21 (RAC1) activated kinase 3 (Pak3),
            transcript variant X2, mRNA.
ACCESSION   XM_030251248
VERSION     XM_030251248.2
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000086.8) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_030251248.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9065
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="X"
     gene            1..9065
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /note="p21 (RAC1) activated kinase 3; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 18 ESTs, 1879 long SRA reads, 7 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 11 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:18481"
                     /db_xref="MGI:MGI:1339656"
     CDS             918..2597
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /codon_start=1
                     /product="serine/threonine-protein kinase PAK 3 isoform
                     X1"
                     /protein_id="XP_030107108.1"
                     /db_xref="GeneID:18481"
                     /db_xref="MGI:MGI:1339656"
                     /translation="MSDSLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNK
                     KARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCP
                     GKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDK
                     SAHGYIAAHQSNTKTASEPPLAPPVSEEEDEEEEEEEDDNEPPPVIAPRPEHTKSIYT
                     RSVVESIASPAAPNKEDIPPSAENANSTTLYRNTDRQRKKSKMTDEEILEKLRSIVSV
                     GDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRE
                     NKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDF
                     LHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT
                     RKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFR
                     DFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR"
ORIGIN      
        1 tttgcataat gccacctgtt ttgaaatgta tatttcatgt acagaagact gttttttatc
       61 ctgcttaaat tgctaccttt cttaatttca ccgccacata ctccccacca cacacaccct
      121 cgtacttgtc tatgtaacct gctaggctga caggtggtgt cccaaatcca aatttcctca
      181 agaaagcctg ctccagtaga tgggttccct agcctgaaac gcatctcaaa gcctagtgtt
      241 tgtaacccag aaagatgcat gaaatgttcc ctctccactc ctgtctggtg tctttctcaa
      301 tggctccacc ttcctcttta gacaatcctg acagtgtaga agtttccatc tcccttccct
      361 ctcctctctc cacccccttc actttctccc ccctcctagg gcgcttcctg cctggaaaca
      421 aaagattggt ccccagtagc ccactcaggg cgattttact tttatgctca ccatctgatt
      481 ggcctaggta cggtgcagag cccaggtgac gtcatagcat agctagggag cggttgctga
      541 gcagaggggc tctacagtag gcaggcagct gtggccgcaa actgtctggg gtcttacgct
      601 gggggctgta gctttttctc ctctgggagt aagtgcattg ggtgaaagaa gagccgtggg
      661 gggagcgagc cgggcccggg gctgcggctg cggccgctgg gctgcagctc cccagcccaa
      721 ctgccagcgt gctccgaggt actggaaagg tcttggcagg gtggctggac ccttggcaga
      781 ctcaaatcca ggccaactgt atggctgtct gaggtgttgg aacagaagga ggtccattcc
      841 tgttggtgac agcactgtgg ccctgttcta ggatgagcca ggtataaaag gagctgtgaa
      901 atcagctgca actgaaaatg tctgacagct tggataacga agaaaaaccc ccagctcccc
      961 cactgaggat gaacagtaac aaccgagact cttcagcact caaccacagc tccaaaccac
     1021 tgcccatggc cccggaagag aagaataaga aagccaggct tcgctctatc ttcccaggag
     1081 gaggggataa aaccaataag aagaaagaga aagagcgccc agagatctct cttccttcag
     1141 actttgagca tacgattcat gtgggttttg atgcagtcac cggggaattc actccagatc
     1201 tctatggctc acagatgtgc ccagggaagc tcccagaggg aattcctgag caatgggcac
     1261 gactactcca aacctccaac ataacaaagc tggaacagaa gaagaaccca caagctgttc
     1321 ttgatgttct caagttctac gactccaaag aaacggtcaa caaccagaaa tatatgagct
     1381 ttacgtcagg agataaaagt gcccatggat acatagcagc acatcagtcg aataccaaaa
     1441 cagcttcgga acctcctttg gctcctcctg tatctgaaga agaggatgaa gaagaggaag
     1501 aggaagaaga tgacaatgaa cctccgcctg tcattgcacc aagaccagag catacaaaat
     1561 caatctatac tcgctccgtg gttgagtcaa ttgcttcacc agctgcacca aataaagaag
     1621 atatcccacc ttctgctgag aatgccaatt ccaccacttt gtacaggaat acagatcggc
     1681 aaagaaaaaa gtccaagatg acggatgagg agatcctaga gaagctgaga agcattgtga
     1741 gtgttgggga cccaaagaag aaatatacga gatttgaaaa aattggccaa ggggcatcag
     1801 gaactgttta cacagcacta gacattgcga ctggacaaga ggtggccata aagcaaatga
     1861 accttcaaca gcagcccaaa aaggaattaa ttattaatga aattcttgtc atgagggaaa
     1921 ataagaaccc caatattgtc aattatttag atagctactt agtgggtgat gaactgtggg
     1981 tagtcatgga atacttggct ggtggctctt tgactgatgt ggtcacagaa acctgtatgg
     2041 atgaaggaca gatagcagct gtctgtagag agtgcctcca agctttggat ttcttgcact
     2101 caaaccaagt gatccacaga gacataaaga gcgacaacat tctcctcggg atggatggtt
     2161 ctgttaaact gactgatttt gggttctgtg ctcaaatcac tcctgagcaa agtaaacgaa
     2221 gcactatggt gggaactccc tattggatgg cacctgaagt ggtaactcga aaagcttatg
     2281 gtccaaaagt tgatatctgg tctctgggaa tcatggccat tgaaatggtg gaaggtgaac
     2341 ccccttacct taatgaaaat ccactcaggg ccttatatct gatagccact aatgggaccc
     2401 cagagctcca gaatcctgag agactgtcag ctgtattccg tgacttctta aatcgctgtc
     2461 ttgagatgga tgtggataga agaggatctg ctaaggagct tttgcagcat ccgtttttaa
     2521 aattagccaa gcctctgtct agtctcactc ctctgattat cgccgcaaag gaagcaatta
     2581 agaacagtag ccgttagaac tgcaagcctt acccctcacg gtctccagga tgagtaagac
     2641 tgaaataaaa ctctgctgca ggatccacag aagaagagac agtcaaatgg agtgggggct
     2701 ctttaacttt taagtgaata gaaacttctt ataaaccttt ttcctactcc ctcagattat
     2761 gtaatttatt tgtaagcctg aactgcagcc cacacagggc agcaatgtcg aagtagccat
     2821 taagtggcca cttccaccgt gaagcgaaag agccagtagt gaatcccctc attttgtgca
     2881 tttactttga agaaaaaaag atttctcaaa gatgcacact ccctcttcat agtgctgtgt
     2941 ttgtttttaa gttagagagt agtccctctt tcattcgaac ctctttcaaa atcccttacc
     3001 caacgtgatg ttttttcact tgcattgtca ttagatgttc agaaaaataa aagatgtcaa
     3061 aatgtttttt taaaaaagaa aaccaaaaaa gaaaaaaaga aaaaacaaaa caaaaaccaa
     3121 caaaaatgaa aaaaaaaaaa atagaacaag tgccgtgtga agccgtggac gtccatgccc
     3181 taatagagtc gcaagctttt cttcttcttc tgtagtggtg gcttgatttg tctacccatt
     3241 ttctgcattt gtattggaaa aggtttcctt taagacattt tccaaaacca gagaggacta
     3301 tgagtgttca ggatggtctt ttaaacgttg tgtcataaca aagctcgaat tgtgagatcc
     3361 tttcacattt cgcatggatg ctaatgtagt agttgaattg tcatgtaaag cagcttgttg
     3421 gcctctgtga taacagaaaa aggacacact gaaaatgtgg cagtgctgct gggtgagtcc
     3481 aggtgatcct aaacctagga tatcctgatg agagaaacct tacttacaca aagatgggac
     3541 tttgtctgag agccaaaagg aaaatgcatc actcctcatt gggcagtaaa taagcaaaga
     3601 taatagtgaa tttattcctc tcttgtgcgc ctgtaacata agcattgtac aataggcaca
     3661 ttctgaggaa atagatccat tagccaatgc ttttcatgat aaaaatattc atttttgggc
     3721 aatttgtaac acataagaat tttttaaaga gctagagatc agagatatag taaagtattc
     3781 aactctttaa gaaatggaaa gtcaatgaaa gttacatccc agttaacaca tggctctaaa
     3841 tacttgaaaa tgatttttct atgtatctcc aatctctttt tcggcacttg atcttggtat
     3901 gttcttattt agtttcttgg gcttttgtcc tttaaaagca tgttcataaa ggtgttggaa
     3961 gttcaccaaa aaatttaatt ttgatctgta ttcatatttc ctaagaaata gcccaatgga
     4021 attccttttg tggcttgagg aaaattccaa aatttgacta ttatttcact atttatagtt
     4081 attaaaaatt tattaatctt ctgtgagtag aaaaacatct ggaaggtgtc tgcatagaaa
     4141 aggatatgtc tcttttgagt gtatagtcag ttgtatgaat tctagaaagt tgtttctcta
     4201 agcctttgac aagccaacaa tctatgttat atggcatttc ttaatttgta gagttagaga
     4261 aactgaatag acattaccta cattcagtgg ggggagcaag atgaggagca gatgcccctc
     4321 tgccctgtga ggtccatctg tccatttaag catccatcct ttccttgaag tgaaagcact
     4381 ttctctagag tttctgctga tcatctagta catatgttta tgttgagaga tggtaccact
     4441 ggtggatttc ctattttcct atattagaag atttgggagg ggtttactca ttccctgaaa
     4501 atatccacca tggaataaaa gacaaatgtg aaaagaaaat caaatgatta tattaatttc
     4561 aagtttattt tgcaaagaga tatctgggcc taaaatttaa atgtcacacc tctttagtga
     4621 gagaggagga accttaattt tttattctac tttattttaa attgaggatt ttcccacttg
     4681 ttgtgccagg gaattccaca aaatacctgg gatgtaaata gaatccaatt gattgatggt
     4741 tatgctcagc taatagagag aacccaaacc ctggttggga agtccaagac atcagttaac
     4801 accttttgca tgttgtaaag gcctttatta ttgttgctgt tgttcttgtt cttgttgttc
     4861 ctgttgttgt tatccttatt tagaagaccc tggagctgtg gtccttcagg tcactgttgg
     4921 cagagaaatg gctgttcttg atgccctcca ctctgcctat taacagtgaa gggccaggta
     4981 cttatttacc atcactttgt atcaagattt aatagtctgt tccagtaggc attacttgta
     5041 caaaattata cctgtgtaca ttttcaaatg agaacagctt ctaaagtctt ttacttgtgt
     5101 tgaagagtta catatatttc taataagtat tagagagaaa ctatttctca tgccaaaatg
     5161 atgctgaagg gtccatactt gctatacttg aacaacttag cctccagatg gttagtagtt
     5221 tattcccttt ccttgatttc attttgagct catcttaatc caggtgaggc tgttcagatc
     5281 tttaacatta ctagtgtgcc ctgagacatt tgtgggcaca tttttgaatg tcaattcaaa
     5341 aatgtcccga ggtaagaata gggcagtggc aaagtcaggg aggggtgaga agcacagtaa
     5401 agtttattta tttaagaaag aatagaacat taatattgta gcaaggatcc agtttgttgt
     5461 caaaatccca tgtggttttg gggatgacgt aatcccccta aatcaatcaa catgttggat
     5521 aatgacttcg ttcttgctga tcttgtctgt gtgttattgt aaatatttgt gagtccatgc
     5581 tccattttgg ctactggatg gccaagtcac atgaaaagat ttaactcaag tatttattct
     5641 ttaattgtgt tcttcagatt tctttcaggc atatgaattg cacctccaat gtttagttga
     5701 accacctatt cctcacatct atccctcccc tatgaagcac attccattgc taaaagaaaa
     5761 aaaaaagaaa tataaattgc ttcctgtttt ctgtataact gttttgatag tttaagatgt
     5821 ttgtctataa tggatatctc tcacctcaaa gatcgtgtaa ataattatat ccatttcctc
     5881 aatgggtcgt ttctttctaa tgaggctgcc agttctcaga gagagtctat gaagtcactt
     5941 ttaaataata cacacaggga ttacatctat gtaaaaagaa gtgtgaatat ggataaagac
     6001 tgggaacaca gaaaactgaa atcagttgtg atagggtggt ggggttctgt gatttttttt
     6061 ctttccgaaa ttttctttct ttgatattga tatattaata atttaagtaa ataaacaaca
     6121 gaaggggaac tatagaaaca tagaagagat gccagaagca ggtgccttct ggccagagcc
     6181 cagagcatgc agggcacaga tatttcctag ttacaattat tctgtaggct ttatacttgc
     6241 ctgggtactg aggttggcac acgctcaggt atggcacatg ctttcttatg agactattat
     6301 ctaagtcaag ctaaggagac atcactgcta gaactttaaa tgcattcttc tgctacaaaa
     6361 caggctgccc tcagctttaa tatggcatcc aggtatgtat tttgtttgcc ttagattgga
     6421 gggctgacaa cctaattagc cccattaata atacttgttt tagatgccac ctttctagct
     6481 tgttttaaaa gattttcaag gtcaattttg gaaggataga agggaaaaat agctagtttc
     6541 caccagcttc ttgcataaca gggcctatca ttctgatagg agtctttttt caataactat
     6601 agacaaatcc cattggtttc catggaaatt accatataca attaagccta actctaaaat
     6661 tattaagaga aatatttaag attgctaata ttcagttcca ggccagtact aagcctatta
     6721 gttttggctt gggatggtct ctttatgccc ttgtgctgca tgattgtagc atgtaggcag
     6781 caattgtggt tttttttttc tttagaaagg gagaccaggc atgaaagggc aattttcttc
     6841 taactcacca aagaaatttt aggtgaggac ttcactaatg tatgtttcac agtgtcatca
     6901 aaagcagacc atatccctag aaaactcaca ggcatttact tagctattca taatacatat
     6961 ggaagtctta accctgccat cctggttgaa tctagtcctt ttctgagctc tttgaagtta
     7021 atattcactc aaacaaatga atggcgtgtg gtataaacat ctcccagtct tggaagaaga
     7081 agcctgaaat tcagcatttg taaactgaca gtctaatggg cctgggattt ggaataactt
     7141 taacatacaa tattgaacat atatttgcat gtggattgga aaggaagtaa atagggcctt
     7201 gggaataagg gaaatgtttc tcctatgaaa gagtttttca taaaagactt atttctacta
     7261 taatttctgg tttttgactt tcagttttat ctcttctttt ctgcttcaca ctccttcagt
     7321 gatcaaatat atctaaccaa cctctaatgc atggggatgt ctgtttatca tcaaacagta
     7381 tctcactgaa tctgcaaatg tgggacttga gatatcacca tgtgcacacc tctgactata
     7441 caaacactac caacttgtag cattgactgc cacttaagtc cattgaactt gcaaggtgaa
     7501 cttagaaaat ctaagtagtg ccaccagaca cagaagctgc catcaggtga atgctgtctc
     7561 attataccat tagtaaggca agtaccatgt tcatctgagt cagtgcctag gcaaaaactg
     7621 acactaatgg tagagaagaa gaactaacca tacccaggaa ggagacctag atgttagcat
     7681 ggctgtttta ccgaactctg tgaccgcgag caaatcactt aacccttcta ttttattcat
     7741 ctataaaata agggtattga agtaactgct cttcaaggtc tttccaaaag ttttgacatt
     7801 gtgtggggta acagtttccc ttgcaagttc aacctgacaa agtgatggca agtatcacaa
     7861 gcttaagcct ggatctctac tttgcagctc catagaacca tgtacaatag aaaaattcaa
     7921 gtaaataaag ttaacagcac cagggaataa tgttgatcaa actcatggaa accttccaac
     7981 ttcctcacaa atgttttgtt tttattttaa tgtctttttt ccactgaatg ttcccagttt
     8041 tccttttcta tacactgtac gtaaaatctg gtttccatta agctgtggct agcatttgct
     8101 actagaacag aaattcactg tcacatttca tagaataaaa ctgtactttg ggcctctcta
     8161 ttcctatgag gcagttatgg gtcttagagc attaaagtaa aaatggcgca ggatggcaga
     8221 acccaagcat tttaatggct aagataacag agtggaccta tgtacggaca agttgcaaaa
     8281 tgagcaaccg aaaaatagca attgcatgct tttaactggc aaattaaatg ttgggatcaa
     8341 agaaaacatt tctcgtggaa attcccacag caattggcta gttatttgag tatggtgctg
     8401 aaaaagaaga gaggctagaa gttagtttaa tggatggtcc ctattgcctg cctacagcag
     8461 agtgtcaacc agcccggagt gtgaaattca agttcaatgt gtgtgcttgt gtgtggtgtg
     8521 ctttctggac ccacatatac tatattcatt agtgatggta agatctttca ccattaatgg
     8581 gttgagctta aaaatctcag tagatctgac agtagctgcc agattacatg gatgccgatg
     8641 tctactgggg ttgaactcat aacatccaga taaactagat tgaggaggat ctccattttc
     8701 accgtttatc ggagttgtat ctcatttggc tgtgcattac ttttgtcaaa atgtgttgtt
     8761 atttgttaac ccatgtgtag tgaacttctt ctgtaatttt ggattaatgg tatttatggt
     8821 cttatgtttg tttggttttt aagtaagtta tttcttttgt agatttgctg atggtatgac
     8881 tccatccctc tgccctcagc agctgatctt tttaaggatt ttcatttctg atattgttat
     8941 tttaaattgt ggttgaagca atagaaattt gaaatatgga ttgtgcatga ctgtgtcttg
     9001 agtgtaaaaa tattacagtt tgaaacttgg acctaaagta ttgcaaataa aacgacaaac
     9061 atcaa
//
