LOCUS       NM_001195048            8352 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus p21 (RAC1) activated kinase 3 (Pak3), transcript
            variant 3, mRNA.
ACCESSION   NM_001195048
VERSION     NM_001195048.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8352)
  AUTHORS   Pang,Y., Ruan,X., Liu,W., Hou,L., Yin,B., Shu,P. and Peng,X.
  TITLE     MicroRNA-495 Modulates Neuronal Layer Fate Determination by
            Targeting Tcf4
  JOURNAL   Int J Biol Sci 20 (15), 6207-6221 (2024)
   PUBMED   39664574
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8352)
  AUTHORS   Viou,L., Atkins,M., Rousseau,V., Launay,P., Masson,J., Pace,C.,
            Murakami,F., Barnier,J.V. and Metin,C.
  TITLE     PAK3 activation promotes the tangential to radial migration switch
            of cortical interneurons by increasing leading process dynamics and
            disrupting cell polarity
  JOURNAL   Mol Psychiatry 29 (8), 2296-2307 (2024)
   PUBMED   38454080
  REMARK    GeneRIF: PAK3 activation promotes the tangential to radial
            migration switch of cortical interneurons by increasing leading
            process dynamics and disrupting cell polarity.
REFERENCE   3  (bases 1 to 8352)
  AUTHORS   Zhao,R., Moore,E.L., Gogol,M.M., Unruh,J.R., Yu,Z., Scott,A.R.,
            Wang,Y., Rajendran,N.K. and Trainor,P.A.
  TITLE     Identification and characterization of intermediate states in
            mammalian neural crest cell epithelial to mesenchymal transition
            and delamination
  JOURNAL   Elife 13, 92844 (2024)
   PUBMED   38873887
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8352)
  AUTHORS   Bolamperti,S., Saito,H., Heerdmann,S., Hesse,E. and
            Taipaleenmaki,H.
  TITLE     Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts
            by activating PAK3 signaling
  JOURNAL   Elife 13, 94265 (2024)
   PUBMED   38661167
  REMARK    GeneRIF: Tgif1-deficiency impairs cytoskeletal architecture in
            osteoblasts by activating PAK3 signaling.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8352)
  AUTHORS   Lee,H., Kang,H., Moon,C. and Youn,B.
  TITLE     PAK3 downregulation induces cognitive impairment following cranial
            irradiation
  JOURNAL   Elife 12, 89221 (2023)
   PUBMED   38131292
  REMARK    GeneRIF: PAK3 downregulation induces cognitive impairment following
            cranial irradiation.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 8352)
  AUTHORS   Murphy,G.A., Solski,P.A., Jillian,S.A., Perez de la Ossa,P.,
            D'Eustachio,P., Der,C.J. and Rush,M.G.
  TITLE     Cellular functions of TC10, a Rho family GTPase: regulation of
            morphology, signal transduction and cell growth
  JOURNAL   Oncogene 18 (26), 3831-3845 (1999)
   PUBMED   10445846
REFERENCE   7  (bases 1 to 8352)
  AUTHORS   Burbelo,P.D., Kozak,C.A., Finegold,A.A., Hall,A. and Pirone,D.M.
  TITLE     Cloning, central nervous system expression and chromosomal mapping
            of the mouse PAK-1 and PAK-3 genes
  JOURNAL   Gene 232 (2), 209-215 (1999)
   PUBMED   10352232
REFERENCE   8  (bases 1 to 8352)
  AUTHORS   Leeuw,T., Wu,C., Schrag,J.D., Whiteway,M., Thomas,D.Y. and
            Leberer,E.
  TITLE     Interaction of a G-protein beta-subunit with a conserved sequence
            in Ste20/PAK family protein kinases
  JOURNAL   Nature 391 (6663), 191-195 (1998)
   PUBMED   9428767
REFERENCE   9  (bases 1 to 8352)
  AUTHORS   Burbelo,P.D., Drechsel,D. and Hall,A.
  TITLE     A conserved binding motif defines numerous candidate target
            proteins for both Cdc42 and Rac GTPases
  JOURNAL   J Biol Chem 270 (49), 29071-29074 (1995)
   PUBMED   7493928
REFERENCE   10 (bases 1 to 8352)
  AUTHORS   Bagrodia,S., Taylor,S.J., Creasy,C.L., Chernoff,J. and Cerione,R.A.
  TITLE     Identification of a mouse p21Cdc42/Rac activated kinase
  JOURNAL   J Biol Chem 270 (39), 22731-22737 (1995)
   PUBMED   7559398
  REMARK    Erratum:[J Biol Chem 1996 Jan 12;271(2):1250]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK158893.1, AL691499.8, BX813331.2 and BX530055.9.
            
            Transcript Variant: This variant (3) differs in the 5' UTR and
            lacks an in-frame exon in the 5' coding region, compared to variant
            1. This results in a shorter protein (isoform C), compared to
            isoform A.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK158893.1, AK031853.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-670               AK158893.1         2-671
            671-671             AL691499.8         112404-112404
            672-2367            AK158893.1         672-2367
            2368-5301           BX813331.2         11561-14494
            5302-8352           BX530055.9         2001-5051
FEATURES             Location/Qualifiers
     source          1..8352
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 64.5 cM"
     gene            1..8352
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /note="p21 (RAC1) activated kinase 3"
                     /db_xref="GeneID:18481"
                     /db_xref="MGI:MGI:1339656"
     exon            1..173
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            174..375
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            376..476
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            477..521
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            522..675
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            676..713
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            714..845
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            846..1011
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1075
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            1076..1124
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            1125..1237
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1355
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            1356..1455
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..1652
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            1653..1790
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     exon            1791..8352
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8329..8334
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /note="hexamer: AATAAA"
     polyA_site      8348
                     /gene="Pak3"
                     /gene_synonym="PAK-3; Pak65alpha; Pak65beta; Stk4"
                     /note="major polyA site"
ORIGIN      
        1 gtcgtcgtcc tcctcctacc actgctgctg ctgtgatcgc ctatcccctc atccttcttc
       61 cttgccaatt cctgttcctc ctccccgcat cccggctcct cctgcccagc agctaaaggc
      121 agaatcgtcg gcagcagctt tccttctctc ctgcctcaaa gaggttgaaa caggagctgt
      181 gaaatcagct gcaactgaaa atgtctgaca gcttggataa cgaagaaaaa cccccagctc
      241 ccccactgag gatgaacagt aacaaccgag actcttcagc actcaaccac agctccaaac
      301 cactgcccat ggccccggaa gagaagaata agaaagccag gcttcgctct atcttcccag
      361 gaggagggga taaaaccaat aagaagaaag agaaagagcg cccagagatc tctcttcctt
      421 cagactttga gcatacgatt catgtgggtt ttgatgcagt caccggggaa ttcactccag
      481 atctctatgg ctcacagatg tgcccaggga agctcccaga gggaattcct gagcaatggg
      541 cacgactact ccaaacctcc aacataacaa agctggaaca gaagaagaac ccacaagctg
      601 ttcttgatgt tctcaagttc tacgactcca aagaaacggt caacaaccag aaatatatga
      661 gctttacgtc aggagataaa agtgcccatg gatacatagc agcacatcag tcgaatacca
      721 aaacagcttc ggaacctcct ttggctcctc ctgtatctga agaagaggat gaagaagagg
      781 aagaggaaga agatgacaat gaacctccgc ctgtcattgc accaagacca gagcatacaa
      841 aatcaatcta tactcgctcc gtggttgagt caattgcttc accagctgca ccaaataaag
      901 aagatatccc accttctgct gagaatgcca attccaccac tttgtacagg aatacagatc
      961 ggcaaagaaa aaagtccaag atgacggatg aggagatcct agagaagctg agaagcattg
     1021 tgagtgttgg ggacccaaag aagaaatata cgagatttga aaaaattggc caaggggcat
     1081 caggaactgt ttacacagca ctagacattg cgactggaca agaggtggcc ataaagcaaa
     1141 tgaaccttca acagcagccc aaaaaggaat taattattaa tgaaattctt gtcatgaggg
     1201 aaaataagaa ccccaatatt gtcaattatt tagatagcta cttagtgggt gatgaactgt
     1261 gggtagtcat ggaatacttg gctggtggct ctttgactga tgtggtcaca gaaacctgta
     1321 tggatgaagg acagatagca gctgtctgta gagagtgcct ccaagctttg gatttcttgc
     1381 actcaaacca agtgatccac agagacataa agagcgacaa cattctcctc gggatggatg
     1441 gttctgttaa actgactgat tttgggttct gtgctcaaat cactcctgag caaagtaaac
     1501 gaagcactat ggtgggaact ccctattgga tggcacctga agtggtaact cgaaaagctt
     1561 atggtccaaa agttgatatc tggtctctgg gaatcatggc cattgaaatg gtggaaggtg
     1621 aaccccctta ccttaatgaa aatccactca gggccttata tctgatagcc actaatggga
     1681 ccccagagct ccagaatcct gagagactgt cagctgtatt ccgtgacttc ttaaatcgct
     1741 gtcttgagat ggatgtggat agaagaggat ctgctaagga gcttttgcag catccgtttt
     1801 taaaattagc caagcctctg tctagtctca ctcctctgat tatcgccgca aaggaagcaa
     1861 ttaagaacag tagccgttag aactgcaagc cttacccctc acggtctcca ggatgagtaa
     1921 gactgaaata aaactctgct gcaggatcca cagaagaaga gacagtcaaa tggagtgggg
     1981 gctctttaac ttttaagtga atagaaactt cttataaacc tttttcctac tccctcagat
     2041 tatgtaattt atttgtaagc ctgaactgca gcccacacag ggcagcaatg tcgaagtagc
     2101 cattaagtgg ccacttccac cgtgaagcga aagagccagt agtgaatccc ctcattttgt
     2161 gcatttactt tgaagaaaaa aagatttctc aaagatgcac actccctctt catagtgctg
     2221 tgtttgtttt taagttagag agtagtccct ctttcattcg aacctctttc aaaatccctt
     2281 acccaacgtg atgttttttc acttgcattg tcattagatg ttcagaaaaa taaaagatgt
     2341 caaaatgttt ttttaaaaaa gaaaaccaaa aaagaaaaaa agaaaaaaca aaacaaaaac
     2401 caacaaaaat gaaaaaaaaa aaaatagaac aagtgccgtg tgaagccgtg gacgtccatg
     2461 ccctaataga gtcgcaagct tttcttcttc ttctgtagtg gtggcttgat ttgtctaccc
     2521 attttctgca tttgtattgg aaaaggtttc ctttaagaca ttttccaaaa ccagagagga
     2581 ctatgagtgt tcaggatggt cttttaaacg ttgtgtcata acaaagctcg aattgtgaga
     2641 tcctttcaca tttcgcatgg atgctaatgt agtagttgaa ttgtcatgta aagcagcttg
     2701 ttggcctctg tgataacaga aaaaggacac actgaaaatg tggcagtgct gctgggtgag
     2761 tccaggtgat cctaaaccta ggatatcctg atgagagaaa ccttacttac acaaagatgg
     2821 gactttgtct gagagccaaa aggaaaatgc atcactcctc attgggcagt aaataagcaa
     2881 agataatagt gaatttattc ctctcttgtg cgcctgtaac ataagcattg tacaataggc
     2941 acattctgag gaaatagatc cattagccaa tgcttttcat gataaaaata ttcatttttg
     3001 ggcaatttgt aacacataag aattttttaa agagctagag atcagagata tagtaaagta
     3061 ttcaactctt taagaaatgg aaagtcaatg aaagttacat cccagttaac acatggctct
     3121 aaatacttga aaatgatttt tctatgtatc tccaatctct ttttcggcac ttgatcttgg
     3181 tatgttctta tttagtttct tgggcttttg tcctttaaaa gcatgttcat aaaggtgttg
     3241 gaagttcacc aaaaaattta attttgatct gtattcatat ttcctaagaa atagcccaat
     3301 ggaattcctt ttgtggcttg aggaaaattc caaaatttga ctattatttc actatttata
     3361 gttattaaaa atttattaat cttctgtgag tagaaaaaca tctggaaggt gtctgcatag
     3421 aaaaggatat gtctcttttg agtgtatagt cagttgtatg aattctagaa agttgtttct
     3481 ctaagccttt gacaagccaa caatctatgt tatatggcat ttcttaattt gtagagttag
     3541 agaaactgaa tagacattac ctacattcag tggggggagc aagatgagga gcagatgccc
     3601 ctctgccctg tgaggtccat ctgtccattt aagcatccat cctttccttg aagtgaaagc
     3661 actttctcta gagtttctgc tgatcatcta gtacatatgt ttatgttgag agatggtacc
     3721 actggtggat ttcctatttt cctatattag aagatttggg aggggtttac tcattccctg
     3781 aaaatatcca ccatggaata aaagacaaat gtgaaaagaa aatcaaatga ttatattaat
     3841 ttcaagttta ttttgcaaag agatatctgg gcctaaaatt taaatgtcac acctctttag
     3901 tgagagagga ggaaccttaa ttttttattc tactttattt taaattgagg attttcccac
     3961 ttgttgtgcc agggaattcc acaaaatacc tgggatgtaa atagaatcca attgattgat
     4021 ggttatgctc agctaataga gagaacccaa accctggttg ggaagtccaa gacatcagtt
     4081 aacacctttt gcatgttgta aaggccttta ttattgttgc tgttgttctt gttcttgttg
     4141 ttcctgttgt tgttatcctt atttagaaga ccctggagct gtggtccttc aggtcactgt
     4201 tggcagagaa atggctgttc ttgatgccct ccactctgcc tattaacagt gaagggccag
     4261 gtacttattt accatcactt tgtatcaaga tttaatagtc tgttccagta ggcattactt
     4321 gtacaaaatt atacctgtgt acattttcaa atgagaacag cttctaaagt cttttacttg
     4381 tgttgaagag ttacatatat ttctaataag tattagagag aaactatttc tcatgccaaa
     4441 atgatgctga agggtccata cttgctatac ttgaacaact tagcctccag atggttagta
     4501 gtttattccc tttccttgat ttcattttga gctcatctta atccaggtga ggctgttcag
     4561 atctttaaca ttactagtgt gccctgagac atttgtgggc acatttttga atgtcaattc
     4621 aaaaatgtcc cgaggtaaga atagggcagt ggcaaagtca gggaggggtg agaagcacag
     4681 taaagtttat ttatttaaga aagaatagaa cattaatatt gtagcaagga tccagtttgt
     4741 tgtcaaaatc ccatgtggtt ttggggatga cgtaatcccc ctaaatcaat caacatgttg
     4801 gataatgact tcgttcttgc tgatcttgtc tgtgtgttat tgtaaatatt tgtgagtcca
     4861 tgctccattt tggctactgg atggccaagt cacatgaaaa gatttaactc aagtatttat
     4921 tctttaattg tgttcttcag atttctttca ggcatatgaa ttgcacctcc aatgtttagt
     4981 tgaaccacct attcctcaca tctatccctc ccctatgaag cacattccat tgctaaaaga
     5041 aaaaaaaaag aaatataaat tgcttcctgt tttctgtata actgttttga tagtttaaga
     5101 tgtttgtcta taatggatat ctctcacctc aaagatcgtg taaataatta tatccatttc
     5161 ctcaatgggt cgtttctttc taatgaggct gccagttctc agagagagtc tatgaagtca
     5221 cttttaaata atacacacag ggattacatc tatgtaaaaa gaagtgtgaa tatggataaa
     5281 gactgggaac acagaaaact gaaatcagtt gtgatagggt ggtggggttc tgtgattttt
     5341 tttctttccg aaattttctt tctttgatat tgatatatta ataatttaag taaataaaca
     5401 acagaagggg aactatagaa acatagaaga gatgccagaa gcaggtgcct tctggccaga
     5461 gcccagagca tgcagggcac agatatttcc tagttacaat tattctgtag gctttatact
     5521 tgcctgggta ctgaggttgg cacacgctca ggtatggcac atgctttctt atgagactat
     5581 tatctaagtc aagctaagga gacatcactg ctagaacttt aaatgcattc ttctgctaca
     5641 aaacaggctg ccctcagctt taatatggca tccaggtatg tattttgttt gccttagatt
     5701 ggagggctga caacctaatt agccccatta ataatacttg ttttagatgc cacctttcta
     5761 gcttgtttta aaagattttc aaggtcaatt ttggaaggat agaagggaaa aatagctagt
     5821 ttccaccagc ttcttgcata acagggccta tcattctgat aggagtcttt tttcaataac
     5881 tatagacaaa tcccattggt ttccatggaa attaccatat acaattaagc ctaactctaa
     5941 aattattaag agaaatattt aagattgcta atattcagtt ccaggccagt actaagccta
     6001 ttagttttgg cttgggatgg tctctttatg cccttgtgct gcatgattgt agcatgtagg
     6061 cagcaattgt ggtttttttt ttctttagaa agggagacca ggcatgaaag ggcaattttc
     6121 ttctaactca ccaaagaaat tttaggtgag gacttcacta atgtatgttt cacagtgtca
     6181 tcaaaagcag accatatccc tagaaaactc acaggcattt acttagctat tcataataca
     6241 tatggaagtc ttaaccctgc catcctggtt gaatctagtc cttttctgag ctctttgaag
     6301 ttaatattca ctcaaacaaa tgaatggcgt gtggtataaa catctcccag tcttggaaga
     6361 agaagcctga aattcagcat ttgtaaactg acagtctaat gggcctggga tttggaataa
     6421 ctttaacata caatattgaa catatatttg catgtggatt ggaaaggaag taaatagggc
     6481 cttgggaata agggaaatgt ttctcctatg aaagagtttt tcataaaaga cttatttcta
     6541 ctataatttc tggtttttga ctttcagttt tatctcttct tttctgcttc acactccttc
     6601 agtgatcaaa tatatctaac caacctctaa tgcatgggga tgtctgttta tcatcaaaca
     6661 gtatctcact gaatctgcaa atgtgggact tgagatatca ccatgtgcac acctctgact
     6721 atacaaacac taccaacttg tagcattgac tgccacttaa gtccattgaa cttgcaaggt
     6781 gaacttagaa aatctaagta gtgccaccag acacagaagc tgccatcagg tgaatgctgt
     6841 ctcattatac cattagtaag gcaagtacca tgttcatctg agtcagtgcc taggcaaaaa
     6901 ctgacactaa tggtagagaa gaagaactaa ccatacccag gaaggagacc tagatgttag
     6961 catggctgtt ttaccgaact ctgtgaccgc gagcaaatca cttaaccctt ctattttatt
     7021 catctataaa ataagggtat tgaagtaact gctcttcaag gtctttccaa aagttttgac
     7081 attgtgtggg gtaacagttt cccttgcaag ttcaacctga caaagtgatg gcaagtatca
     7141 caagcttaag cctggatctc tactttgcag ctccatagaa ccatgtacaa tagaaaaatt
     7201 caagtaaata aagttaacag caccagggaa taatgttgat caaactcatg gaaaccttcc
     7261 aacttcctca caaatgtttt gtttttattt taatgtcttt tttccactga atgttcccag
     7321 ttttcctttt ctatacactg tacgtaaaat ctggtttcca ttaagctgtg gctagcattt
     7381 gctactagaa cagaaattca ctgtcacatt tcatagaata aaactgtact ttgggcctct
     7441 ctattcctat gaggcagtta tgggtcttag agcattaaag taaaaatggc gcaggatggc
     7501 agaacccaag cattttaatg gctaagataa cagagtggac ctatgtacgg acaagttgca
     7561 aaatgagcaa ccgaaaaata gcaattgcat gcttttaact ggcaaattaa atgttgggat
     7621 caaagaaaac atttctcgtg gaaattccca cagcaattgg ctagttattt gagtatggtg
     7681 ctgaaaaaga agagaggcta gaagttagtt taatggatgg tccctattgc ctgcctacag
     7741 cagagtgtca accagcccgg agtgtgaaat tcaagttcaa tgtgtgtgct tgtgtgtggt
     7801 gtgctttctg gacccacata tactatattc attagtgatg gtaagatctt tcaccattaa
     7861 tgggttgagc ttaaaaatct cagtagatct gacagtagct gccagattac atggatgccg
     7921 atgtctactg gggttgaact cataacatcc agataaacta gattgaggag gatctccatt
     7981 ttcaccgttt atcggagttg tatctcattt ggctgtgcat tacttttgtc aaaatgtgtt
     8041 gttatttgtt aacccatgtg tagtgaactt cttctgtaat tttggattaa tggtatttat
     8101 ggtcttatgt ttgtttggtt tttaagtaag ttatttcttt tgtagatttg ctgatggtat
     8161 gactccatcc ctctgccctc agcagctgat ctttttaagg attttcattt ctgatattgt
     8221 tattttaaat tgtggttgaa gcaatagaaa tttgaaatat ggattgtgca tgactgtgtc
     8281 ttgagtgtaa aaatattaca gtttgaaact tggacctaaa gtattgcaaa taaaacgaca
     8341 aacatcaatg tt
//
