LOCUS       NM_177326               5741 bp    mRNA    linear   ROD 13-MAY-2024
DEFINITION  Mus musculus p21 (RAC1) activated kinase 2 (Pak2), mRNA.
ACCESSION   NM_177326 XM_148586 XM_358817
VERSION     NM_177326.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5741)
  AUTHORS   Hu,B., Moiseev,D., Schena,I., Faezov,B., Dunbrack,R., Chernoff,J.
            and Li,J.
  TITLE     PAK2 is necessary for myelination in the peripheral nervous system
  JOURNAL   Brain 147 (5), 1809-1821 (2024)
   PUBMED   38079473
  REMARK    GeneRIF: PAK2 is necessary for myelination in the peripheral
            nervous system.
REFERENCE   2  (bases 1 to 5741)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 5741)
  AUTHORS   Zeng,J., Wang,S., Gao,M., Lu,D., Song,S., Chen,D., Fan,W., Xu,Z.,
            Zhang,Z. and Sun,X.
  TITLE     PAK2 is essential for chromosome alignment in metaphase I oocytes
  JOURNAL   Cell Death Dis 14 (2), 150 (2023)
   PUBMED   36813765
  REMARK    GeneRIF: PAK2 is essential for chromosome alignment in metaphase I
            oocytes.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5741)
  AUTHORS   Wang,Y., Zhang,K., Guo,J., Yang,S., Shi,X., Pan,J., Sun,Z., Zou,J.,
            Li,Y., Li,Y., Fan,T., Song,W., Cheng,F., Zeng,C., Li,J., Zhang,T.
            and Sun,Z.S.
  TITLE     Loss-of-Function of p21-Activated Kinase 2 Links BMP Signaling to
            Neural Tube Patterning Defects
  JOURNAL   Adv Sci (Weinh) 10 (4), e2204018 (2023)
   PUBMED   36504449
  REMARK    GeneRIF: Loss-of-Function of p21-Activated Kinase 2 Links BMP
            Signaling to Neural Tube Patterning Defects.
REFERENCE   5  (bases 1 to 5741)
  AUTHORS   Kathania,M., Kumar,R., Lenou,E.T., Basrur,V., Theiss,A.L.,
            Chernoff,J. and Venuprasad,K.
  TITLE     Pak2-mediated phosphorylation promotes RORgammat ubiquitination and
            inhibits colonic inflammation
  JOURNAL   Cell Rep 40 (11), 111345 (2022)
   PUBMED   36103814
  REMARK    GeneRIF: Pak2-mediated phosphorylation promotes RORgammat
            ubiquitination and inhibits colonic inflammation.
REFERENCE   6  (bases 1 to 5741)
  AUTHORS   Hayashi,K., Ohshima,T. and Mikoshiba,K.
  TITLE     Pak1 is involved in dendrite initiation as a downstream effector of
            Rac1 in cortical neurons
  JOURNAL   Mol Cell Neurosci 20 (4), 579-594 (2002)
   PUBMED   12213441
REFERENCE   7  (bases 1 to 5741)
  AUTHORS   Lee,K.K. and Yonehara,S.
  TITLE     Phosphorylation and dimerization regulate nucleocytoplasmic
            shuttling of mammalian STE20-like kinase (MST)
  JOURNAL   J Biol Chem 277 (14), 12351-12358 (2002)
   PUBMED   11805089
REFERENCE   8  (bases 1 to 5741)
  AUTHORS   Kissil,J.L., Johnson,K.C., Eckman,M.S. and Jacks,T.
  TITLE     Merlin phosphorylation by p21-activated kinase 2 and effects of
            phosphorylation on merlin localization
  JOURNAL   J Biol Chem 277 (12), 10394-10399 (2002)
   PUBMED   11782491
  REMARK    GeneRIF: phosphorylation of merlin at serine 518 is induced by the
            p21-activated kinase PAK2
REFERENCE   9  (bases 1 to 5741)
  AUTHORS   Burbelo,P.D., Kozak,C.A., Finegold,A.A., Hall,A. and Pirone,D.M.
  TITLE     Cloning, central nervous system expression and chromosomal mapping
            of the mouse PAK-1 and PAK-3 genes
  JOURNAL   Gene 232 (2), 209-215 (1999)
   PUBMED   10352232
REFERENCE   10 (bases 1 to 5741)
  AUTHORS   Zambrowicz,B.P., Friedrich,G.A., Buxton,E.C., Lilleberg,S.L.,
            Person,C. and Sands,A.T.
  TITLE     Disruption and sequence identification of 2,000 genes in mouse
            embryonic stem cells
  JOURNAL   Nature 392 (6676), 608-611 (1998)
   PUBMED   9560157
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK037275.1 and AK220528.1.
            
            On Nov 27, 2013 this sequence version replaced NM_177326.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK037275.1, BC086650.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1020              AK037275.1         2-1021
            1021-2568           AK037275.1         1023-2570
            2569-5741           AK220528.1         1398-4570
FEATURES             Location/Qualifiers
     source          1..5741
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 22.4 cM"
     gene            1..5741
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /note="p21 (RAC1) activated kinase 2"
                     /db_xref="GeneID:224105"
                     /db_xref="MGI:MGI:1339984"
     exon            1..255
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     exon            256..463
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             277..1851
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /EC_number="2.7.11.1"
                     /note="gamma-PAK; p21-activated kinase 2; p21 protein
                     (Cdc42/Rac)-activated kinase 2"
                     /codon_start=1
                     /product="serine/threonine-protein kinase PAK 2"
                     /protein_id="NP_796300.1"
                     /db_xref="CCDS:CCDS28112.1"
                     /db_xref="GeneID:224105"
                     /db_xref="MGI:MGI:1339984"
                     /translation="MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVP
                     EEKKPRNKIISIFSGTEKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQW
                     ARLLQTSNITKLEQKKNPQAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNTK
                     GSETSAVVTEEDDDDEDAAPPVIAPRPDHTKSIYTRSVIDPIPAPVGDSNVDSGAKSS
                     DKQKKKAKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVA
                     IKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDV
                     VTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQ
                     ITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR
                     ALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSS
                     LTPLILAAKEAMKSNR"
     exon            464..564
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     exon            565..712
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     exon            713..744
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     exon            745..852
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     exon            853..985
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1049
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1098
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1099..1211
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1212..1329
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1330..1429
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..1626
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1627..1764
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..5741
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3657..3662
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /note="hexamer: AATAAA"
     polyA_site      3683
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /note="major polyA site"
     regulatory      4138..4143
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /note="hexamer: ATTAAA"
     polyA_site      4168
                     /gene="Pak2"
                     /gene_synonym="5330420P17Rik; A130002K10Rik; D16Ertd269e;
                     mKIAA4182; PAK-2"
                     /note="major polyA site"
ORIGIN      
        1 cccagggttg tggccacgcg cagcggcagc ggttgttccg cttcccctcc ggcccgggcc
       61 gtcgccattg ccgaaggctc ctgccctccc ctccctggcc caaggggttc tgcgcctcac
      121 ggcctcggta gcgacggccg cgccccgcgc cgctcccctc cgccctgccc tcctccctct
      181 cagcgcccca gcgcagtgct cgcccgcgtc ggccaagcag cccgccctgg gtcgggcgga
      241 gacctttcct ctctggctgt ttcataattc tgaatcatgt ctgataacgg agagctagaa
      301 gacaagcccc cagcacctcc agttcggatg agcagtacca tttttagcac cggaggaaaa
      361 gatcctttat cagccaatca cagtttgaaa cctttgcctt ctgttccaga ggaaaaaaaa
      421 cccaggaaca aaatcatctc catattctct ggcacagaaa aaggaagtaa aaagaaagaa
      481 aaagaacggc cagagatttc tcccccatct gattttgagc acaccatcca tgttggcttt
      541 gatgctgtta cgggagagtt cactggcatg ccagaacagt gggcgcggct gttgcagacc
      601 tccaacatta ccaaactcga gcagaagaag aaccctcagg cagtgctgga tgtcttgaag
      661 ttctacgact ccaacactgt gaaacagaag tacctgagtt tcactcctcc tgagaaagat
      721 ggcttccctt ctggaacacc agcactgaac accaaggggt cagagacatc agctgtagtg
      781 acagaggaag atgatgatga tgaagacgct gctcctcccg tcattgcccc tcggccagat
      841 catacaaaat caatttacac acggtctgtc atcgacccca ttcctgctcc agttggtgat
      901 tctaatgttg acagtggtgc caagtcttca gacaaacaga aaaagaaagc caagatgacc
      961 gatgaagaga ttatggagaa attaagaact attgtgagca taggggaccc aaagaaaaaa
     1021 tacacaagat atgaaaaaat tgggcaaggg gcttctggaa cagtttttac tgccactgat
     1081 gtggccctgg ggcaagaggt tgctatcaag cagattaatt tacagaaaca accaaagaag
     1141 gaattgatca ttaatgaaat tctggtgatg aaagagttaa agaatcccaa catagttaac
     1201 ttcttggaca gttacctggt aggagatgag ttgtttgtgg taatggagta cctcgctggt
     1261 gggtccctca ctgatgttgt aacagaaacc tgcatggacg aagcgcagat tgccgccgtg
     1321 tgcagagagt gtttacaggc gttggagttt ttacatgcta atcaagtgat ccacagagac
     1381 atcaaaagtg acaatgtgct tttgggaatg gaaggctcag ttaaacttac tgacttcggc
     1441 ttctgtgccc agatcactcc tgaacagagc aaacgcagta ctatggttgg aacaccgtac
     1501 tggatggcac cagaggtggt gacacggaaa gcctatggtc ccaaagttga catatggtct
     1561 ctgggcatca tggctatcga gatggttgaa ggagagcctc catacctcaa cgaaaatcct
     1621 ctgcgggcat tatacctgat agctacaaat ggaactcctg aacttcagaa tccagaaaaa
     1681 ctttccccaa tatttcggga tttcttaaat cggtgtttgg aaatggatgt ggagaaaagg
     1741 ggttcggcca aggaactgtt acagcatcct ttcctgaaac tggccaaacc attgtctagc
     1801 ttgacgccac tgatcctggc agctaaagaa gcaatgaaga gtaaccgcta acatcgtcac
     1861 cgaggcctcc tattccctta tccatttttt aaaagaagtc ttttaataca tgaaattgtt
     1921 actctgaggg gtgtaaagag acagtctgca tcacatggag gaaaaaaaaa actattattt
     1981 tctaaagatg accaagagaa aattgcagta agagagctat gactttgaaa tgagcccctg
     2041 ctttagggtc caagaggaac ggtggactgc atcactagcc ttacatgtcc cgcagaccgc
     2101 gcttgacgtt cgcatactgt gtgatgactt ttagtatggc agatcctgtt cctgtctccc
     2161 ctgggggatt tcccatactt gaatgtcaga ttcaagtttt tctgagtatt tcatctgctg
     2221 atcttctctc cttcgtgacc ttcccttcct ctaacccttt ccttttaagt tgtcgttcgg
     2281 agtttttctt atgcctaaat gcaaggcaga tgtgataaaa tgattgatgt agctctttac
     2341 attgggaaag gagcttgaca tgcttagctt cctatagaag tcaggaccgg ctggtgtgcg
     2401 gagtgtttca gttcagagcc taaactgaaa gggggaaagt atgtgatttt tacctttttt
     2461 aacaaatgtg aaagagtcag ctttagaaat tttgtggtag taagtttgac atttgttaca
     2521 tgtatagaaa gaggactaat aatctatatt tataactaaa tcattgatac agagaagaaa
     2581 aatcccactg actgtatatt ctcaccattt tgtagtcttt ctctgcctgt ttctcctcat
     2641 atttggcttt aggaaccaaa gtgatctgcg cttgttgacg cgggctgtgt gactttggtg
     2701 ccactccctt cctgtgtttc cttggaaata agtgtctgta tatgttgtga ttttaggtgt
     2761 ccgttttgaa tcaaccctta tttcacatac accccctcca ccctctaggg caagtaataa
     2821 ccattgaatt ttcagaattt aaaagttaaa agatttttcc tatttaaaag gaaaaatatt
     2881 tgggactagc agaaaccaag tgagatttga accttggtga gttctaggct agttgtaata
     2941 atgaaatgtc aatattgtag aggtgaagtt tctgacagta aactgtaaag actcatctaa
     3001 tctacagtgt tcctgaccca ttatcaatgt tttactgttt atgacagatg aaatagtgca
     3061 gtacttgatg gatcatttga ggtgttgggt actttagtgt ttgtttttcc aaatgagtag
     3121 ggtattcatt gtaaaaaaac aaaaacaaaa aacaaactgg agaaaggaaa ctgcagtgtt
     3181 cgtattgtta gtaatacttt tattttaaag atttaataaa aggtctgtga cctgtagtag
     3241 tagctgttag ctgccctctc cccactcctg cctttcctct tctctgcttc tctgtattgc
     3301 tttgttgttt tgcctgtgag gaggtattgc tgtctatcct atggtcctgc aaccatagga
     3361 aagaaaatcc ctgtggttgg ttcaggtttg tccccaccat cccctttcaa agaacgtgac
     3421 acatactcgc cctgccattc tgcagagtac aaatcataaa tgagtaagtt tgctctttgg
     3481 gttgggggaa ggggcagggt ttcatttcct ggtgttccca ttagaataca ggataagaag
     3541 agatcactag gggctttcag caaaagtcaa catctagagc acttactggc ctgttttcca
     3601 tgcgagctcc ttttcctctg gactgtattt tcctacagct ttcactaaat tacaggaata
     3661 aagtggtttc tttgtggtgg gaagctaggc tgcctcttga gttctggctg tgagtgttgt
     3721 ttgtgagccg ctgtctggat agattgtgat gacagtgctg ccagcataga agaaagccag
     3781 ctacatggtg gcactgctta agaaggtgct ccatcctcaa tcctcgagag caccggggac
     3841 acaggctgct gcccctcctt aggctgtgac tccacaccgg cttgtccaca cagaagcagt
     3901 ctggggtttg tccttagaat ttcttggatg gttatttaca tgtccattgc tggcgacgga
     3961 ctctgtcatt caaacctgac tccaaggtta agggagctgc actgtgcttt attctctcct
     4021 gacctggaca aactaacctg gaatagttaa tcgtaatggt taattttgag atgtgtcatt
     4081 tttaaacaga ataatcttta aagcaatata gaattgtgat ttattagtta attttaaatt
     4141 aaaattttga gatcctgttg aaagacaatt gtatgaattg agattctttt tttttttttt
     4201 ttttaaagac ttgcctctgt attccctctt ttgccatctc ttagagtaag aatccccatt
     4261 ggagcctccc ttagtcctct tgtgtcctta ggaactgttt gccctaccac ttatttatta
     4321 ccttgcagtc tttgtggtgg ccgcaaaggc atcttctctc cttctgctgc actctgttta
     4381 cagagcacca tagccaccca cagcagttag aaggagcgtg agtgcagctt gctgcaccat
     4441 gaccagcata gctctgtctg cacgcattga gttcccttca acagacagct gtctgtccag
     4501 tgaccaccag tcctaaatgt gctatgccga aatatctctt catgggctca tgtgtatgca
     4561 ctgtgttctt gcctgcatgc tttatacctt atcagaccat ggttagaatt agaaggtagg
     4621 tgttgaaaca ggctgcatcc agttttgaat atgaaaatct tagaagcata ctgagatctg
     4681 caatcactaa actgtcagaa tgtatgggcc ccgtgagcat tgggcagggg cagtgtctgc
     4741 ttatcctagc cactagatca ggagaaggaa ttccttctcg ttggcatctg acctcagcag
     4801 acactccccc cgcctgctcc cacacggtta tcatagataa tacaatgttt tctttctttt
     4861 ctgagacagt cttgctgtat aggcctggtt agcttagatg agtctagcct ggaacccaca
     4921 gctatctacc tgcctctgct gcccagtagt ggaataatgg catgcaccac tgtgtcctgt
     4981 ttaaactttt ttctaatgtc gtttcaggct atatagttaa tgggtccagg agtgtagctc
     5041 agtggtgagt cacatgccta tcatgcacaa agccccaagc ttgaacccgt gctccactaa
     5101 aaacagtatc taggccacta cttgacagta ttgtataatt tcaaatttta aaaaaattgc
     5161 taaaatcttg ttaaatgttt ccttttggtt ttctaacaat cgcactgaca ggacagattg
     5221 ctctgtcagc gctgttctgt gatgcgtatg tgtgatgttc tgtgaagtgg cttttctgaa
     5281 gctgcgtgta ggaaacatcc ccacacattc cctctcttat cagtacatcc gctgaccact
     5341 ctggcagaga tgctgtgttt gatattagag ttacgaacag attcaagcat tggcctggtc
     5401 ttgaaagaac tcaagtcttt ctcattcact accctatgct aaaaacagat aaccttgtca
     5461 aacatgctat ttctgcgtca agaaaaacaa ttagttgaag ttcaaagaaa ggagtcactt
     5521 ttttatgtat ttattttttg gtttgctttc cttgttttgg taggtagaaa ttgagttggg
     5581 taaaaagcct atttctattt tgttttcaga ttttatattg ccttctattt ttaatttaat
     5641 ctaacataat caactgtact ttgctataac tgctgtattt gttgactgaa taattttgtt
     5701 ctttcagggc tagaaataaa ctttcatgtc cattttcttt t
//
