LOCUS       NM_146169               3330 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus poly(A) binding protein interacting protein 2B
            (Paip2b), mRNA.
ACCESSION   NM_146169 XM_978166
VERSION     NM_146169.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3330)
  AUTHORS   Khoutorsky,A., Yanagiya,A., Gkogkas,C.G., Fabian,M.R.,
            Prager-Khoutorsky,M., Cao,R., Gamache,K., Bouthiette,F.,
            Parsyan,A., Sorge,R.E., Mogil,J.S., Nader,K., Lacaille,J.C. and
            Sonenberg,N.
  TITLE     Control of synaptic plasticity and memory via suppression of
            poly(A)-binding protein
  JOURNAL   Neuron 78 (2), 298-311 (2013)
   PUBMED   23622065
REFERENCE   2  (bases 1 to 3330)
  AUTHORS   Delbes,G., Yanagiya,A., Sonenberg,N. and Robaire,B.
  TITLE     PABP interacting protein 2A (PAIP2A) regulates specific key
            proteins during spermiogenesis in the mouse
  JOURNAL   Biol Reprod 86 (3), 95 (2012)
   PUBMED   22190698
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3330)
  AUTHORS   Yanagiya,A., Delbes,G., Svitkin,Y.V., Robaire,B. and Sonenberg,N.
  TITLE     The poly(A)-binding protein partner Paip2a controls translation
            during late spermiogenesis in mice
  JOURNAL   J Clin Invest 120 (9), 3389-3400 (2010)
   PUBMED   20739757
REFERENCE   4  (bases 1 to 3330)
  AUTHORS   Berlanga,J.J., Baass,A. and Sonenberg,N.
  TITLE     Regulation of poly(A) binding protein function in translation:
            Characterization of the Paip2 homolog, Paip2B
  JOURNAL   RNA 12 (8), 1556-1568 (2006)
   PUBMED   16804161
REFERENCE   5  (bases 1 to 3330)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY262990.1, AK173114.1 and CK381272.1.
            
            On Jun 18, 2008 this sequence version replaced NM_146169.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC034096.1, AK159287.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-450               BY262990.1         2-451
            451-3319            AK173114.1         393-3261
            3320-3330           CK381272.1         375-385
FEATURES             Location/Qualifiers
     source          1..3330
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 35.97 cM"
     gene            1..3330
                     /gene="Paip2b"
                     /note="poly(A) binding protein interacting protein 2B"
                     /db_xref="GeneID:232164"
                     /db_xref="MGI:MGI:2386865"
     exon            1..107
                     /gene="Paip2b"
                     /inference="alignment:Splign:2.1.0"
     exon            108..165
                     /gene="Paip2b"
                     /inference="alignment:Splign:2.1.0"
     CDS             137..547
                     /gene="Paip2b"
                     /note="PAIP-2B; PABP-interacting protein 2B"
                     /codon_start=1
                     /product="polyadenylate-binding protein-interacting
                     protein 2B"
                     /protein_id="NP_666281.2"
                     /db_xref="CCDS:CCDS20287.1"
                     /db_xref="GeneID:232164"
                     /db_xref="MGI:MGI:2386865"
                     /translation="MTTLNTGSARISIMNGSSVASTSPSVKCKEDQGLNGHEEKENPF
                     AEYMWMENEEDFNRQVEEELQEQDFLDRCFQEMLDEEDQDWFIPARDLPQAVGHLQQQ
                     LNGLSVGDSHESEDILSKSNLNPDAKEFVPGVKY"
     exon            166..313
                     /gene="Paip2b"
                     /inference="alignment:Splign:2.1.0"
     exon            314..490
                     /gene="Paip2b"
                     /inference="alignment:Splign:2.1.0"
     exon            491..3325
                     /gene="Paip2b"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      733
                     /gene="Paip2b"
                     /note="major polyA site"
     regulatory      863..868
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Paip2b"
                     /note="hexamer: AATAAG"
     polyA_site      882
                     /gene="Paip2b"
                     /note="major polyA site"
ORIGIN      
        1 gtgtgaggcc gaggtacctc gagcgtttgt gcgccgaggc tcgcgctctt aggaggcggc
       61 gctgtgctgt ggtgcggacc tcggggcggc gttgtccgcg cggccaggca cctggaaggg
      121 tgaaggcgag aggcagatga cgacgctgaa cacaggctcc gcaagaatct ccataatgaa
      181 tggatccagt gtggcaagta catcacccag tgtgaaatgc aaagaagacc aaggattaaa
      241 tggacatgag gaaaaggaaa acccatttgc agaatacatg tggatggaaa atgaagagga
      301 tttcaacaga caggtggagg aagagctaca ggagcaagac ttcttggacc gctgcttcca
      361 ggagatgctg gatgaagagg accaggactg gttcatccca gcacgagacc tgcctcaggc
      421 tgtggggcac ttacaacagc agttaaatgg actatcagtt ggtgacagtc atgaatctga
      481 agacattttg agcaaaagta acctgaatcc agatgccaag gagtttgttc caggagtgaa
      541 gtactgagct gttggaagct tccagaagga cttgtcttgt ccccgtacct ggggccagca
      601 atgcacaaaa agggcggagc tgaagggggg tggcaagggt gtgcagccag ggcgggttgg
      661 gttgggaagg tggtttaact ggatattgtg actctgagta actaatgtgc gaggtacaac
      721 tctccaagcc tgagcatggc tcttctgttg tgcagacttg ctcagagcag tttccaattt
      781 attttatttt tgatgagctc tttggagtta aggaactgcg attgtttttc ccttgtaagg
      841 aatgttgtct gcattttagc aaaataagct gaccaaggaa aacagtattt aagaataatt
      901 ttccctgctg tgtacctacc agcagcaggg ttcctggaga acttaaggag tttgcagctg
      961 ggtgataagg gggaaaacat gagatacaaa ccagatataa catgcagctc ccatcccctg
     1021 atatttccat gatgaactgg gataccagtg gcccataaag ctcttgtctc ctgtcctgaa
     1081 ctcagctcaa gagaacacag atttgaaagt tcttggatga ctgtaacttt ggatggatgt
     1141 gagttgtata tcagaaaagc agggcttgat ggtgattgtc attagtgact gctatcctat
     1201 cattagtatg tagctattgt cactcatcag ggttgctttg ccttcatgat cttcatgggg
     1261 gctgcttctg gcttctttcc cccctcagct ctaaaagaca ctattagtca aagtctgaga
     1321 tgggccttca gttgtgttag ttacaccttg aaccttttct ggacagtttt gttttcctaa
     1381 gtcccttcaa tatctgattc ttaggatgtc ttaattccct tatattttct gtgtttccag
     1441 acactaacaa gctgcttagt ttgggttttt ctcatgcctt acagagtgat ttccagaaac
     1501 taaggtgctg aggggtcctg cccgagagca caacaatcag gcttgctatg tacttgaagc
     1561 tgttagtagg tgttactgtt cccacagacc agctttagtg tcctcatggt cctgcctagg
     1621 tgcactctta gttctagctc taactcacta gggtttttgt tggtgttctg tggaactgaa
     1681 ctgcaccaga agctgccgct gtgagtcgag gtgaaggtgg tagtgtctga gggtgagaga
     1741 acaagtgtcc tgtcctgatc gtactccgag gacaagggtc ttgggaggac tgatagtgct
     1801 gtggcttctg tgtggctatc actgtggtga atgacaggtc tggaaagatc atgctgcttc
     1861 cagcagtcca tcagatcagt gtatagatat gggcagagac tggaaggaga ggactgaggt
     1921 ctggaaagtt gaaagtttcc ctttttcata tgaactggtt tgctgagttt ccattttttc
     1981 ttggtgccat ggatagaacc cagagtctca cttgtgccag gttagtccta cccttgagct
     2041 gttctcaacc ctcccttgat ttgaacacag ccccagcagt taaagacaga tgtccctctt
     2101 tttcctgttt gagtcatcac aaggatggca tcttgtggaa gtggcctccc tctcaggtca
     2161 catcctagtg agtagctcag ggaacttgta tggccagaca cacacatcaa ttcaaagcct
     2221 ctccatcaag agagaatgaa actaggaact ccttctggaa tgactttatt cctgtttaag
     2281 cttttagctt ggcttgtcac ctctaataag gagaggagga gggtatgtgt aggacattta
     2341 aaaagattct ttctcttgta gtctccatga ggtcaggctg tatcaggatt gcaggaagat
     2401 ccttcagaat ctctgtttgc gtagtgcacc ttcctctgag cacctatgga aagcttatgc
     2461 aagcctgagg cagctttgtt ccatccttca gttttgctct ttggaagcca agctgctagg
     2521 aatggtccaa gaggcctgcc tccctcccgc tgtgctggct cattttattt ggatgtcatt
     2581 ctttatcctg ctttcagggg tgtatgctgt tgggtatacc tggaatccaa gagctagtgt
     2641 gttgagtcaa cctcagaggc agggtgctga ctgtaggctt gggatgcagc cagtgaactg
     2701 gcccttagta atgtatggaa tgacttattc ctgtgaccca actcttttac tatccagtgt
     2761 tgtgaggaag cacaattgta cccgagacta cagacttagc cccaattaca aaaaagtttt
     2821 gggttgtttt ttttccttgg aattcttaga ttgctgtgta aattcttata cagcaataga
     2881 aagcattcta aatagctgct agtctgcctg gtctcagtat tcatttatta gagactgagt
     2941 tctgtgatta tttgacccta ttaactttgg ggggtgggga ggaaggaatt attcatgaat
     3001 tttggactac atcagaaatc tgagatatcc aaagccttgg tactgtagct cagggtcagg
     3061 ggccagtttc tatctgtagt gtacctgact tatggttatc atataaacaa gccaggagat
     3121 attctaagga gaagattggg tcctttttat tgaacccagg acctcacatg tgttatgcaa
     3181 gcactacacc aagctgtact ccaggcccgt gaaaggttga gactgggtta gcactatttc
     3241 caaagtcaca agacctatga ttgcttcatt aagattgtaa ggttaaccat ggcttaaaaa
     3301 taaatggttt tggtgaacta ctaaaaaaaa
//
