LOCUS       NP_663432                400 aa            linear   ROD 01-MAY-2025
DEFINITION  polyadenylate-binding protein-interacting protein 1 isoform 1 [Mus
            musculus].
ACCESSION   NP_663432 XP_983536 XP_989277
VERSION     NP_663432.1
DBSOURCE    REFSEQ: accession NM_145457.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 400)
  AUTHORS   Yin,G., Jia,S., Zhang,Y., Xian,Y., Guo,Y. and Liu,Q.
  TITLE     YAP1-activated ZNF131 promotes hepatocellular carcinoma cell
            proliferation through transcriptional regulation of PAIP1
  JOURNAL   Arch Biochem Biophys 754, 109921 (2024)
   PUBMED   38341068
  REMARK    GeneRIF: YAP1-activated ZNF131 promotes hepatocellular carcinoma
            cell proliferation through transcriptional regulation of PAIP1.
REFERENCE   2  (residues 1 to 400)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (residues 1 to 400)
  AUTHORS   Xie,H., Yang,L., Hu,Q., Song,Y., Wang,X., Zhou,L. and Li,L.
  TITLE     Effects of inducing apoptosis and inhibiting proliferation of siRNA
            on polyadenylate-binding protein-interacting protein 1 in tongue
            cell carcinoma
  JOURNAL   Head Neck 42 (12), 3623-3637 (2020)
   PUBMED   32827170
  REMARK    GeneRIF: Effects of inducing apoptosis and inhibiting proliferation
            of siRNA on polyadenylate-binding protein-interacting protein 1 in
            tongue cell carcinoma.
REFERENCE   4  (residues 1 to 400)
  AUTHORS   He,Y., Lin,Y., Zhu,Y., Ping,P., Wang,G. and Sun,F.
  TITLE     Murine PAIP1 stimulates translation of spermiogenic mRNAs stored by
            YBX2 via its interaction with YBX2dagger
  JOURNAL   Biol Reprod 100 (2), 561-572 (2019)
   PUBMED   30295753
  REMARK    GeneRIF: PAIP1 regulates the translation of YBX2-masked mRNAs
            during spermiogenesis.
REFERENCE   5  (residues 1 to 400)
  AUTHORS   Cajigas,I., Chakraborty,A., Swyter,K.R., Luo,H., Bastidas,M.,
            Nigro,M., Morris,E.R., Chen,S., VanGompel,M.J.W., Leib,D.,
            Kohtz,S.J., Martina,M., Koh,S., Ay,F. and Kohtz,J.D.
  TITLE     The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially
            Organizes Megabase Distant Genes in the Developing Forebrain
  JOURNAL   Mol Cell 71 (6), 956-972 (2018)
   PUBMED   30146317
REFERENCE   6  (residues 1 to 400)
  AUTHORS   Lo,J.C., Jamsai,D., O'Connor,A.E., Borg,C., Clark,B.J.,
            Whisstock,J.C., Field,M.C., Adams,V., Ishikawa,T., Aitken,R.J.,
            Whittle,B., Goodnow,C.C., Ormandy,C.J. and O'Bryan,M.K.
  TITLE     RAB-like 2 has an essential role in male fertility, sperm
            intra-flagellar transport, and tail assembly
  JOURNAL   PLoS Genet 8 (10), e1002969 (2012)
   PUBMED   23055941
REFERENCE   7  (residues 1 to 400)
  AUTHORS   Pereira,J.D., Sansom,S.N., Smith,J., Dobenecker,M.W.,
            Tarakhovsky,A. and Livesey,F.J.
  TITLE     Ezh2, the histone methyltransferase of PRC2, regulates the balance
            between self-renewal and differentiation in the cerebral cortex
  JOURNAL   Proc Natl Acad Sci U S A 107 (36), 15957-15962 (2010)
   PUBMED   20798045
REFERENCE   8  (residues 1 to 400)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (residues 1 to 400)
  AUTHORS   Yu,J., Farjo,R., MacNee,S.P., Baehr,W., Stambolian,D.E. and
            Swaroop,A.
  TITLE     Annotation and analysis of 10,000 expressed sequence tags from
            developing mouse eye and adult retina
  JOURNAL   Genome Biol 4 (10), R65 (2003)
   PUBMED   14519200
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC163689.3.
            
            On or before May 4, 2006 this sequence version replaced
            XP_983536.1, XP_989277.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC051042.1, SRR7345562.2281949.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 67.22 cM"
     Protein         1..400
                     /product="polyadenylate-binding protein-interacting
                     protein 1 isoform 1"
                     /note="PABP-interacting protein 1; poly(A)-binding
                     protein-interacting protein 1"
                     /calculated_mol_wt=45571
     Region          1..36
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8VE62.1)"
     Region          37..64
                     /region_name="PABPC1-interacting motif-2 (PAM2).
                     /evidence=ECO:0000250|UniProtKB:Q9H074"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8VE62.1)"
     Region          78..296
                     /region_name="PAIP1 middle domain (PAIP1M).
                     /evidence=ECO:0000250|UniProtKB:Q9H074"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8VE62.1)"
     Region          81..297
                     /region_name="MIF4G"
                     /note="MIF4G domain; pfam02854"
                     /db_xref="CDD:397130"
     Region          356..376
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8VE62.1)"
     Region          361..400
                     /region_name="PABPC1-interacting motif-1 (PAM1).
                     /evidence=ECO:0000250|UniProtKB:Q9H074"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8VE62.1)"
     CDS             1..400
                     /gene="Paip1"
                     /gene_synonym="PAIP-1"
                     /coded_by="NM_145457.5:226..1428"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS26796.1"
                     /db_xref="GeneID:218693"
                     /db_xref="MGI:MGI:2384993"
ORIGIN      
        1 msdsfdrape qtkpqrapps sqdkipqqns esamakpqvv vapvlmskls anapefypsg
       61 yssnytesye dgcedyptls eyvqdflnhl teqpgsfete ieqfaetlng wvttddalqe
      121 lveliyqqat sipnfsymga rlcnylshhl tispqsgnfr qlllqrcrte yeakdqaakg
      181 devtrkrfha fvlflgelyl nleikgtngq vtradilqvg lrellnalfs npmddnlica
      241 vkllkltgsv ledtwkekgk tdmeeiiqri envvldancs rdvkqmllkl velrssnwgr
      301 vhatstyrea tpendpnyfm neptfytsdg vpftaadpdy qekyqeller edffpdyeen
      361 gtdlsgagdp ylddiddemd peieeayekf cleserkrkq
//
