LOCUS       NM_001195031            8256 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus phosphoprotein associated with glycosphingolipid
            microdomains 1 (Pag1), transcript variant A, mRNA.
ACCESSION   NM_001195031
VERSION     NM_001195031.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8256)
  AUTHORS   Lucas,R.M., Liu,L., Curson,J.E.B., Koh,Y.W.H., Tuladhar,N.,
            Condon,N.D., Das Gupta,K., Burgener,S.S., Schroder,K., Ingley,E.,
            Sweet,M.J., Stow,J.L. and Luo,L.
  TITLE     SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to
            direct pro-inflammatory signaling in TLR-activated macrophages
  JOURNAL   Cell Rep 36 (10), 109662 (2021)
   PUBMED   34496234
REFERENCE   2  (bases 1 to 8256)
  AUTHORS   Tsuboi,Y., Oyama,M., Kozuka-Hata,H., Ito,A., Matsubara,D. and
            Murakami,Y.
  TITLE     CADM1 suppresses c-Src activation by binding with Cbp on membrane
            lipid rafts and intervenes colon carcinogenesis
  JOURNAL   Biochem Biophys Res Commun 529 (3), 854-860 (2020)
   PUBMED   32616310
  REMARK    GeneRIF: CADM1 suppresses c-Src activation by binding with Cbp on
            membrane lipid rafts and intervenes colon carcinogenesis.
REFERENCE   3  (bases 1 to 8256)
  AUTHORS   Ullah,M.A., Vicente,C.T., Collinson,N., Curren,B., Sikder,M.A.A.,
            Sebina,I., Simpson,J., Varelias,A., Lindquist,J.A., Ferreira,M.A.R.
            and Phipps,S.
  TITLE     PAG1 limits allergen-induced type 2 inflammation in the murine lung
  JOURNAL   Allergy 75 (2), 336-345 (2020)
   PUBMED   31321783
  REMARK    GeneRIF: PAG1 limits allergen-induced type 2 inflammation in the
            murine lung.
REFERENCE   4  (bases 1 to 8256)
  AUTHORS   Plani-Lam,J.H., Slavova-Azmanova,N.S., Kucera,N., Louw,A.,
            Satiaputra,J., Singer,P., Lam,K.P., Hibbs,M.L. and Ingley,E.
  TITLE     Csk-binding protein controls red blood cell development via
            regulation of Lyn tyrosine kinase activity
  JOURNAL   Exp Hematol 46, 70-82 (2017)
   PUBMED   27751872
  REMARK    GeneRIF: our findings illustrate that Cbp is an important regulator
            of Csk recruitment to the SFK Lyn in Eporesponsive erythroid cells.
REFERENCE   5  (bases 1 to 8256)
  AUTHORS   Davidson,D., Zhong,M.C., Pandolfi,P.P., Bolland,S., Xavier,R.J.,
            Seed,B., Li,X., Gu,H. and Veillette,A.
  TITLE     The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation
            in Cooperation with Phosphatase PTPN22 and Dok Adaptors
  JOURNAL   Cell Rep 17 (10), 2776-2788 (2016)
   PUBMED   27926878
REFERENCE   6  (bases 1 to 8256)
  AUTHORS   Van Laethem,F., Liang,X., Andris,F., Urbain,J., Vandenbranden,M.,
            Ruysschaert,J.M., Resh,M.D., Stulnig,T.M. and Leo,O.
  TITLE     Glucocorticoids alter the lipid and protein composition of membrane
            rafts of a murine T cell hybridoma
  JOURNAL   J Immunol 170 (6), 2932-2939 (2003)
   PUBMED   12626544
REFERENCE   7  (bases 1 to 8256)
  AUTHORS   Davidson,D., Bakinowski,M., Thomas,M.L., Horejsi,V. and
            Veillette,A.
  TITLE     Phosphorylation-dependent regulation of T-cell activation by
            PAG/Cbp, a lipid raft-associated transmembrane adaptor
  JOURNAL   Mol Cell Biol 23 (6), 2017-2028 (2003)
   PUBMED   12612075
  REMARK    GeneRIF: PAG is a bona fide negative regulator of T-cell activation
            as a result of its capacity to recruit Csk.
REFERENCE   8  (bases 1 to 8256)
  AUTHORS   Yasuda,K., Nagafuku,M., Shima,T., Okada,M., Yagi,T., Yamada,T.,
            Minaki,Y., Kato,A., Tani-Ichi,S., Hamaoka,T. and Kosugi,A.
  TITLE     Cutting edge: Fyn is essential for tyrosine phosphorylation of
            Csk-binding protein/phosphoprotein associated with
            glycolipid-enriched microdomains in lipid rafts in resting T cells
  JOURNAL   J Immunol 169 (6), 2813-2817 (2002)
   PUBMED   12218089
REFERENCE   9  (bases 1 to 8256)
  AUTHORS   Itoh,K., Sakakibara,M., Yamasaki,S., Takeuchi,A., Arase,H.,
            Miyazaki,M., Nakajima,N., Okada,M. and Saito,T.
  TITLE     Cutting edge: negative regulation of immune synapse formation by
            anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly
  JOURNAL   J Immunol 168 (2), 541-544 (2002)
   PUBMED   11777944
REFERENCE   10 (bases 1 to 8256)
  AUTHORS   Brdicka,T., Pavlistova,D., Leo,A., Bruyns,E., Korinek,V.,
            Angelisova,P., Scherer,J., Shevchenko,A., Hilgert,I., Cerny,J.,
            Drbal,K., Kuramitsu,Y., Kornacker,B., Horejsi,V. and Schraven,B.
  TITLE     Phosphoprotein associated with glycosphingolipid-enriched
            microdomains (PAG), a novel ubiquitously expressed transmembrane
            adaptor protein, binds the protein tyrosine kinase csk and is
            involved in regulation of T cell activation
  JOURNAL   J Exp Med 191 (9), 1591-1604 (2000)
   PUBMED   10790433
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC156996.7, AK040230.1 and AC129945.10.
            
            Transcript Variant: This variant (A) represents the longer
            transcript. Both variants A and B encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK156000.1, AK172106.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-52                AC156996.7         36271-36322         c
            53-450              AK040230.1         2-399
            451-2832            AK040230.1         401-2782
            2833-8256           AC129945.10        109948-115371
FEATURES             Location/Qualifiers
     source          1..8256
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 2.47 cM"
     gene            1..8256
                     /gene="Pag1"
                     /gene_synonym="Cbp; F730007C19Rik; Pag"
                     /note="phosphoprotein associated with glycosphingolipid
                     microdomains 1"
                     /db_xref="GeneID:94212"
                     /db_xref="MGI:MGI:2443160"
     exon            1..469
                     /gene="Pag1"
                     /gene_synonym="Cbp; F730007C19Rik; Pag"
                     /inference="alignment:Splign:2.1.0"
     exon            470..528
                     /gene="Pag1"
                     /gene_synonym="Cbp; F730007C19Rik; Pag"
                     /inference="alignment:Splign:2.1.0"
     exon            529..602
                     /gene="Pag1"
                     /gene_synonym="Cbp; F730007C19Rik; Pag"
                     /inference="alignment:Splign:2.1.0"
     exon            603..809
                     /gene="Pag1"
                     /gene_synonym="Cbp; F730007C19Rik; Pag"
                     /inference="alignment:Splign:2.1.0"
     CDS             679..1968
                     /gene="Pag1"
                     /gene_synonym="Cbp; F730007C19Rik; Pag"
                     /note="phosphoprotein transmembrane adaptor 1;
                     phosphoprotein-associated with GEMs; Csk-binding protein;
                     transmembrane phosphoprotein Cbp"
                     /codon_start=1
                     /product="phosphoprotein associated with
                     glycosphingolipid-enriched microdomains 1"
                     /protein_id="NP_001181960.1"
                     /db_xref="CCDS:CCDS17235.1"
                     /db_xref="GeneID:94212"
                     /db_xref="MGI:MGI:2443160"
                     /translation="MGPAGSVLSSGQMQMQMVLWGSLAAVAMFFLITFLVLLCSTCDR
                     EKKPRQHSGDHENLMNVPSDKDMFSHSATSLTTDALASSEQNGVLTNGDILSEDSTLT
                     CMQHYEEVQTSASDLLDSQDSTGKAKCHQSRELPRIPPENAVDEILTARAADTELGPG
                     VEGPYEVLKDSSSQENMVEDCLYETVKEIKEVADKGQGGKSKSTSALKELQGAPMEGK
                     ADFAEYASVDRNKKCRHSANAESILGTCSDLDEESPPPVPVKLLDENANLPQEGGGQA
                     EEQAAEGTGGHSKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQSAHKPGPCMKGP
                     ESACHSMKGLPQRSSSSCNDLYATVKDFEKTPNSISTLPPARRPSEEPEPDYEAIQTL
                     NREDEKVPLETNGHHVPKESDYESIGDLQQCRDVTRL"
     exon            810..861
                     /gene="Pag1"
                     /gene_synonym="Cbp; F730007C19Rik; Pag"
                     /inference="alignment:Splign:2.1.0"
     exon            862..958
                     /gene="Pag1"
                     /gene_synonym="Cbp; F730007C19Rik; Pag"
                     /inference="alignment:Splign:2.1.0"
     exon            959..1545
                     /gene="Pag1"
                     /gene_synonym="Cbp; F730007C19Rik; Pag"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1605
                     /gene="Pag1"
                     /gene_synonym="Cbp; F730007C19Rik; Pag"
                     /inference="alignment:Splign:2.1.0"
     exon            1606..8256
                     /gene="Pag1"
                     /gene_synonym="Cbp; F730007C19Rik; Pag"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8232..8237
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pag1"
                     /gene_synonym="Cbp; F730007C19Rik; Pag"
                     /note="hexamer: AATAAA"
     polyA_site      8256
                     /gene="Pag1"
                     /gene_synonym="Cbp; F730007C19Rik; Pag"
                     /note="major polyA site"
ORIGIN      
        1 agtcgcgaac atgcgcactg agtcccgcgc gctgctccgc ctcggcgctg tcattctccg
       61 cggcgcggcg gccagtgcgg actgcggttc ccgcccggcg cgcgggtgct gtgactgctc
      121 ctccggggcg gactggtgac tctgcagcgc tctggagcct ctcgtgcggg gactccgtgg
      181 tgtcgcattc cctcagagag ggagacacgc acccggagct ccgagcacag ctctcaaggg
      241 ctggcggcca cgacggcgtt tgctcgggtt cccggtgcag tccgagtctc tgcggccgcc
      301 cggtgcgccc gggagagcgc acctcccccg gcacggcaga accgaggcga cgaggatcag
      361 gagggtcctg cgcccgctac cactgcccac cgcgggccag cccggctgcg agcagcggag
      421 ttgcagcgct ttttagagct ctggagcccc agaagacctc tgcgaaccaa acacactggg
      481 ttcttctctg atttccacag tggagcacaa cttcaaagct gggagttggc caagaaggaa
      541 gagagaaccc cagcatactg acacgtgaac gaaaccctct tctggacaac cgtttctcca
      601 aggaggatga agccttctag acccatgtga tctcctatga agaactgacc ccacctgctg
      661 gtcaccccag ctcccaccat gggccctgca ggaagcgtac tgagcagtgg gcagatgcag
      721 atgcagatgg tcctgtgggg aagtctggct gccgtggcca tgttcttcct catcaccttc
      781 ctcgtcctcc tgtgttccac ttgcgacaga gagaagaagc cacggcagca tagcggggac
      841 catgagaacc tgatgaatgt gccttccgac aaggacatgt tcagccattc ggcaaccagc
      901 ctgacaacag atgcactggc tagcagcgaa cagaacgggg tgctcaccaa tggcgacatt
      961 ctttcagaag acagcacgct gacctgcatg cagcactatg aggaagtcca gacctcggct
     1021 tccgatctcc tggactccca ggacagcaca ggaaaggcca agtgccacca gagccgggag
     1081 ctgcccagga tcccgcctga gaacgccgtg gacgagattc tcacagccag ggctgcagac
     1141 acggaactgg ggcccggagt ggaggggccc tacgaggtgc tcaaggacag ctcctcccag
     1201 gagaacatgg tggaggactg tctgtatgaa acagtgaagg agatcaagga agtggcagac
     1261 aaaggccagg gtggcaagtc caagtccact tctgccttga aggagcttca gggggctccc
     1321 atggagggca aggccgactt tgctgaatat gcctctgtgg acagaaacaa aaagtgccgc
     1381 cacagcgcga acgcagagag cattctggga acttgcagtg acctggacga ggaaagccca
     1441 cctcctgtcc cggttaagct tctggatgag aatgccaacc ttccccagga gggaggagga
     1501 caggcagagg agcaagctgc agaagggacc ggtggacaca gcaagagatt tagttccttg
     1561 tcatacaagt ctcgggaaga agacccgact cttacagaag aggagatctc agcaatgtat
     1621 tcctcagtga ataagcctgg ccagtcggca cacaaacctg gaccatgtat gaaagggcca
     1681 gaatctgcct gccactccat gaagggcctc cctcagaggt cgtcatcttc ctgcaatgac
     1741 ctctatgcca ctgtgaaaga ctttgagaaa actcccaaca gcatcagcac actgcccccg
     1801 gcaaggagac ccagtgagga gccagagcct gactatgaag ccatacagac tctaaacaga
     1861 gaggatgaga aggtccctct ggagaccaat ggccaccatg tccccaagga gagtgactac
     1921 gagagcattg gggacttgca gcaatgcaga gatgtcacca ggctctagca actaaaagag
     1981 gctgtgatca gcagctctgc tgtggaaagg aggtggctgc agtttctcgc tgctttggtt
     2041 gactgaaatc ttcaagtgca gtctcccagt tgtctcccag tttccaaaac agtaaggtac
     2101 ggacctgcct gccagggcag ccaccctcca gtgctcccaa gaaacccctg ggacccctca
     2161 cctccacatt ccacagagga aggccagctg tgggtgctgg cggggaagcc ccacccacca
     2221 atgccaaaat cccactgcct gctgaagaag agccaggttt ccatccttgc tctctttccc
     2281 tctgctcctc atgctaaaac actggcactt cacccctgga gacctcccat gtgtgcttca
     2341 tcccaaggat ggtctcccac tggcctgcac tggccttcag taaatgttag catggagaga
     2401 aactggttgc cgttaaccca ccctcttccc agacctgcct cttagtccct gggaaggaac
     2461 ctggatgtgc aggctgtgag gtatggggtg ggccgtccct ggagtctctg gggttcttgc
     2521 tcctcgttgg acactgcatc tgcagtcttc agaggttcat gaggtcagtt gagatgtttt
     2581 ttaatgttct atgttgaaaa ccttcccaac agtgtttgga ttttcataac tactgtggta
     2641 cttctgtagc tgttcacacc cagtgctctt ccttccaaac agagccttaa tgtttctgtg
     2701 aggatggcag ccatggtgtc tatccccaaa gggctgcgga cataaatgtg ttcccggtgg
     2761 tctttgctgc ccacatgtga ctttcctata atctgatggt aatctgagta aaatgtaaac
     2821 atttatttta ttatataaat ttataagatg ttttatgttt aatgcctaat ttctagaaag
     2881 tgccagaaaa tatatattaa ctatttggat tttatgtaca acgatttata ctctcatttt
     2941 acaaacgata ccataaagca cataagctag ataattataa gcagttttta ttcttttctc
     3001 taatgagtaa tatagcattg aagacttgtt aaggctcaac tcctcagaca gtactgggag
     3061 ttctagatcc aaaacactga ggcactggtg gcaaaatgca atggacataa atgtgtcact
     3121 gctgagacac tcggtgttat aaatagaaca aaatctgact tgggaatcct gaaagtacca
     3181 gactttcact gatgtctagt gacccctcta aagacagcag tggcggtgcc cccgttcagt
     3241 ctctgccgac gcaaattgcc cggttgttca tcgcttcaca ggaatcagta gctgaagcag
     3301 ctcacattga aagttcagtc atcgctctag atcttcccag gccagcattg gaaactctgt
     3361 tcacttttca ttttaagagg agcctcgctg aagtgcagga cacagataaa gagacagcct
     3421 tttctttcct actgccatgt ggcatcttat tctaatgact taagaatcat gctattttcc
     3481 ttccctgtga taaagagtgt gcgtgggaag gtgacatgac cagctctgtg gcctgtcttt
     3541 ccatccttgt actcaccgac tggttgtgga tcatgcctgt ggagctgcaa actctcttgg
     3601 atgttgttgg cattagccta atcctccatg aagatggtgg gcacatggat aagcatcgcc
     3661 tctgctggcc ccgccacagc ggtgggatac cccagggaac tgggagcagt aatgggcaag
     3721 gctgtttgca accactgatt ttcgctgctg tgtattaatg agtttggccc aaccatctct
     3781 caggccacga gggtcccctc atcacatgcc actccccgtg ccacagggcg ctcctggaca
     3841 tgtgcttgcc accatgcaat tccttacagg catcgtatag ctcaggagtt tgattatgtt
     3901 ttataaaaag tcttagcagg aaagctggta tgatctctaa agtataaaac tctttttttc
     3961 tatgaatgca cgctttatta ttcatgtacc gtccagagac atcaaaccca tcagccccct
     4021 gccccaagaa ggaagttgaa aaacattaac agtaaagagc ctttgcccaa gagtcagaga
     4081 tcctatgacc tgccttctct gctttggtgc ccagaagaga gtgtgagact cttcaaggct
     4141 cccagagctt cggggaatcc agggtcattt tgagaggact ctggggttct gcccggtagt
     4201 ccctcttgat gcacagtggc agcagcacag tttccaattc gtgagggcct tagacaaccg
     4261 cttgagcttc atctcacgcc ccttcttgaa gaaatagtac ctgatgtctc cttttgtcag
     4321 tttgagtttg tcagccatgg ccgccagagt cccctcctta gtctttctca aagtgctttt
     4381 ttacttcctg gaactgctca taggtgaacc cagagtatcc atcccagtcg gacagacccc
     4441 gagttgtctc catctcagct acttctatct cttctgcagc tcacttgagt tctgttcttc
     4501 aagattccat aaaactcttt cttcagagat aagttcatta tagataatca tgtcatcttg
     4561 aattcctgtt gtccaaatgt cccagagttt ccaaacgtgg tatgtagcat ggtcatgaag
     4621 tgtgcactga catccctctc ctggtccgag aagctcgcag tggtaagaga acatgtgacg
     4681 ggcgatctca caggttctgt acaaggaacc tggagaccct ctccccaaca taaatccaaa
     4741 ggaatacgca ctagcttgtg aggatacaga ttttagccaa gtgaaagagc aaaagctcac
     4801 agcaaaacaa aagcctggac aatcaagcca aagatgccag cacagcagga aatgtgtggt
     4861 aaccatgtac ctgacgctcg gctgagcaaa gcgagcccct caccagtcag tttgagttac
     4921 ttacttggct aaaatccatg ttcctgtctt tgagctggac ggagcctgta gtttggttta
     4981 aagtctaaat gttacagagt ttaaatatgt gggaaaccat catcaaaagg aggctggact
     5041 gtacactaaa cacctctgag tctacagcag gctggactgt acactaaaca ccaccacaga
     5101 gtatacagcg gtgactatag actcaccaca gactatctta tgtgaaacat ttccaatatt
     5161 ctaaaagaaa gtcattttta taaatgtgtt ggctgcatat ttttgacttg tccttatcta
     5221 aatcacatca ctaagtctgc aaaacttcta aataatacca atactctttg tgggaaaagg
     5281 gttttttgcg tcttttatta tttttacatt gtacctctaa atatttatgt tttcttgttc
     5341 ttcaggttct tttatttaac taaaagatgt ttgttcggat ttttactctc agatggaaat
     5401 tggaagcata attgtgctta aaaggcagca ctaaagatca ttccatttac tattcagata
     5461 gcccagtaca ggctccccct tggattggca ctgctattct gtaggactgc tttggtttgg
     5521 gttgggttgg tttggtttgg tttggtttgg tttggtttgg tttggtttgg tttggtttgg
     5581 tttggtttaa gatctaggaa ctgggcactg cagcccatgc ctgttatcct ataatgaggg
     5641 agagtgggaa agaaggacgg ttttacattc aaggctaact tgggctacaa ggccagagcc
     5701 tattctaaac aaaatgttct ggttatctca aatcacctta tatgtgttgt aaaggttggt
     5761 gacagtccct cctcagactt ctatgttaac ctggcacctg ttcaatgttg ctgttgtatt
     5821 tacatgcctt gtgatttgtg ggggagtttg aaatacaagc agataaatac actgttacaa
     5881 gtagaggctg tagttctcat tccaacaagt tccctcataa ggatggttgg ttgtagcatg
     5941 tccctaaggt tcccagccag tttgaaggta ctcctcttat tcaagtaggg tacaaaatag
     6001 tccaagacac aaagcagtta ctaattatct ctgctgataa ttgtaactat ctgatcatct
     6061 agttcatgaa agagtaaaga ggttttgttc gatgtgaaaa tgcttgaacc ttggctttct
     6121 atgttcaaaa atattcgcat tagcctcgga atcttagggt tcttccctga ctctgatgcc
     6181 cttcaagagg cagaaggact agggtgtgaa gtcagtgttt ccttcccctc acttgcctgc
     6241 tcctgcacag atgacctact gccccttcat ccatttgccg ttgacctcgt ccccatcatg
     6301 agtgtctaca cagctgtcac ctctgtgcca tatctacagc atgtccagct tctcttcagt
     6361 accgctcacc agcctaggtg ggaccactga ctgtgagtct gcagtggcca ccgcccagtc
     6421 tctgtgtctc aagctccaag agacggtcac acactaacct gcaagccaag gctggtgact
     6481 ttgaccatcc ctaacgcatg agttttccat ggaaacctgg tcggtgaacc tgacacgaaa
     6541 ttcccaattc ccctttactc tgtactgtgt ggctggtgct cttgttttcg ttctctctct
     6601 ctctctctct ctctctctct ctctctctct ctctctctct ctctctctct ctctctcaag
     6661 ttgattcctc catgttgctt tacagagacc tgccaactac ccaggaatgt aaaagcattc
     6721 atagtatttg tctagtagag atgctgtatg aaaaatgcca aaaccaaaaa gagaaagaag
     6781 gaaagagaga tagatagatg acatagatga cggatggatg ggtgggtggg tggatggatg
     6841 gatggatgga tggatggatg gatggatggg tgcctagaga gttgagtctg gaactccaat
     6901 cattctatgt atttttagta cattttttaa agtatcaaat acacaattga ctctgaagga
     6961 agacaaaaat agcaaaattt gaactaagtg ttgtgagtag ctcctgcctg tccccacttc
     7021 ccacctgccc gtaaggtcat gtttctcaac cttcccaatg ctgtgacccc ccccccccaa
     7081 acaccaccat gttttattgc catttcataa ctgtaacttt gctactgtta tgaatcataa
     7141 tgtaaatgtc tggtctgcag gatagagaac ccaaaagggg tcttcaccca caggttgagt
     7201 gccagtctta acatgtaaac agtaaatgta aaggattcac ccacaggttg agtgctagtc
     7261 ttaacatgta aacaataaat gtaaaggaag actatgaact caaaggttaa actttttatt
     7321 tagatatttt ctttgtaact caagagtaag ccaagtttga ggaaaattta gtgaggtcat
     7381 taaagttgta aatctgtaag ccagaagaag tagccctccc agtatatttt ttctaaagac
     7441 tttaaactgt tttctctagg aagatcaact cctggaataa aagaacaaag ctcccatagc
     7501 ctttccagca gagcatatat ctgtctgcca ctacccaggt gtctgttctt gtcatagtgt
     7561 ttcaataatt tatactgggg ggagggggaa gtgcatttta aattttcttg gaaaagtgaa
     7621 ttaatgtgtt aaattgtcca gttttgtcta aagagaacga ttcgttttgg agacaagagc
     7681 acagggctgt ggtccctgtc ccaccatcaa gtttactgtg tgacctcaag caaatgattg
     7741 aacttctctg tgcctcagtt tctccatatt acaagatggg gataatgatt accaaccatt
     7801 gcctacctca tagggatatt ttgggaacaa gtcagataat gtaagacaaa ggttttgatc
     7861 tccttaaaag gtgctgtata aactgcggtt gcattgctaa tgatccagca ttgtgtttag
     7921 gattagatga tagcaatact ttttgtcacg ttttagtcga ggcattattt ctactcttct
     7981 gtggccagat cacaaatttt cattcaataa tggtacttaa ggaactgaca cgggtgtttg
     8041 ttttctgtct ctaatgctaa tatgtcaatt ctgaacagtc ataaaagggt ggagttgaac
     8101 ttgtgatggc ttctagttca catggaacaa atcttattca agctgtatat taaaagtata
     8161 attacttgta aatagcaggt acattgtaat taaagacact tattaacttg tctttgttct
     8221 ttttaaattg taataaaggc cagttttata taaaaa
//
