LOCUS       NM_025755               1551 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus PARK2 co-regulated-like (Pacrgl), mRNA.
ACCESSION   NM_025755
VERSION     NM_025755.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1551)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1551)
  AUTHORS   Fratta,P., Sivakumar,P., Humphrey,J., Lo,K., Ricketts,T.,
            Oliveira,H., Brito-Armas,J.M., Kalmar,B., Ule,A., Yu,Y., Birsa,N.,
            Bodo,C., Collins,T., Conicella,A.E., Mejia Maza,A.,
            Marrero-Gagliardi,A., Stewart,M., Mianne,J., Corrochano,S.,
            Emmett,W., Codner,G., Groves,M., Fukumura,R., Gondo,Y., Lythgoe,M.,
            Pauws,E., Peskett,E., Stanier,P., Teboul,L., Hallegger,M.,
            Calvo,A., Chio,A., Isaacs,A.M., Fawzi,N.L., Wang,E., Housman,D.E.,
            Baralle,F., Greensmith,L., Buratti,E., Plagnol,V., Fisher,E.M. and
            Acevedo-Arozena,A.
  TITLE     Mice with endogenous TDP-43 mutations exhibit gain of splicing
            function and characteristics of amyotrophic lateral sclerosis
  JOURNAL   EMBO J 37 (11) (2018)
   PUBMED   29764981
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC101004.6.
            
            On Dec 28, 2021 this sequence version replaced NM_025755.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC018481.1, AK014276.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-102               AC101004.6         76070-76171         c
            103-170             AC101004.6         74318-74385         c
            171-325             AC101004.6         74027-74181         c
            326-393             AC101004.6         72955-73022         c
            394-484             AC101004.6         71400-71490         c
            485-619             AC101004.6         69101-69235         c
            620-727             AC101004.6         68334-68441         c
            728-808             AC101004.6         66698-66778         c
            809-1551            AC101004.6         59720-60462         c
FEATURES             Location/Qualifiers
     source          1..1551
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 26.25 cM"
     gene            1..1551
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /note="PARK2 co-regulated-like"
                     /db_xref="GeneID:66768"
                     /db_xref="MGI:MGI:1914018"
     exon            1..102
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            103..170
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..865
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /codon_start=1
                     /product="PACRG-like protein"
                     /protein_id="NP_080031.1"
                     /db_xref="CCDS:CCDS19281.1"
                     /db_xref="GeneID:66768"
                     /db_xref="MGI:MGI:1914018"
                     /translation="MQRSECSGGVQLRNRATGSNDQRTSSSTQMKHRTTVQRSKSSSL
                     TSSPEAARRARPRPSDKLNPKTINPFGEQPRAPTAFAAIYSQGGIPCRLVHGSVKHRL
                     QWECPPEILPFDPLLITLAEGLRETKHPYTFVSKEGFRELLLVKGAPEKAIPLLPRLI
                     PVLKAALVHSDDEVFERGLSALVQLSVVVGPSLNGHLKLLLTSLSKRLMDKKFKEPIT
                     SALQKLEQHGGNASLIIIKSKIPTYCSICC"
     exon            171..325
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            326..393
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            394..484
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            485..619
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            620..727
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            728..808
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            809..1551
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1038..1043
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1059
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /note="major polyA site"
     regulatory      1526..1531
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1551
                     /gene="Pacrgl"
                     /gene_synonym="4933428G09Rik"
                     /note="major polyA site"
ORIGIN      
        1 gaatcaccgc tgcctgcagc tgtagcagag ggctttggtg cggagagccg gaggggagcc
       61 ccacgagggc ggcggcgagc gccggtggcg gcgggagagg cggggtgaag gagaagctat
      121 gcagagatca gagtgctctg gaggtgtgca gttgagaaac agagcgacag gtagtaatga
      181 tcaacgtaca tcctcaagca cacaaatgaa acacaggact acggttcagc ggagcaaatc
      241 ctcctcatta accagttctc cagaggctgc aagaagggct cgtcctcggc caagtgataa
      301 gctcaaccct aaaaccatta acccttttgg tgaacaacca cgggccccta ctgcattcgc
      361 agctatttac tctcagggag gcattccttg cagattggta catggctcag taaaacacag
      421 attacagtgg gaatgcccgc ctgaaattct tccatttgac ccgcttctaa ttacgttagc
      481 tgagggtctg agggagacca agcatcctta tacttttgtg tcaaaggaag gctttaggga
      541 gttgcttctg gtcaagggtg ctcctgaaaa agctatccct ttgctacctc gactgatccc
      601 tgtgctgaag gcagctctag ttcattctga tgatgaagtg tttgaaagag gactgagcgc
      661 actcgtgcag ctgagtgtgg tggttggccc gtctctgaat ggccatctga aacttctgct
      721 tacaagtctt tcgaagaggc taatggacaa aaaattcaaa gagcccatca ccagtgctct
      781 gcaaaagctg gagcagcacg gcggaaatgc aagtcttatc atcatcaaat ccaaaatccc
      841 aacgtattgc tccatctgct gttgaataag ggaggccaca aaagccacgc cttcctcagg
      901 cactgaggtg gctgcctgga ccttttgtca gttcagttca ttccgactca cggcatcatt
      961 cattcattaa ctcggctacg gggaccgtgc caagttcgga agaatcatca tacaggatgc
     1021 ttgtcaacaa aaagttaatt aaagtaatgt gcgtaaaaac gttgagtgct gtaggggttt
     1081 ctcatccatc atacctatgc attttccaat gcatttctcc tcccaggcca tctgcaggtg
     1141 actctgtagc agtgccttat tttctaggtt ggctttggcc atttcttggt ttttatattt
     1201 atcaagactg aaaaagtttt acgatagcaa gtaaacattt gtgactgaac tattagccgg
     1261 aatgtggaaa tgtgtatttt ataatgtggg aaactttggg aatatcattt ttgtcctgaa
     1321 tattctagtt taaaaacttg ttttaaatgt caaaattcta ttactatttg tttgttgttt
     1381 attacaactt tttaaactac ctaaacttta ggtgttaatt gtaattaagt aaatgctatt
     1441 tttgcatttt gtagccccac aatactgatg atgatgagtg tgtttgtgtg tgtgtgtgtg
     1501 cgcgcgtata tacagatatt cggaaattaa aatcttactt gtattcagtg a
//
