LOCUS       NM_011033               2586 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus poly(A) binding protein, cytoplasmic 2 (Pabpc2), mRNA.
ACCESSION   NM_011033 XM_988736
VERSION     NM_011033.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2586)
  AUTHORS   Kashiwabara S, Tsuruta S, Okada K, Saegusa A, Miyagaki Y and Baba
            T.
  TITLE     Functional compensation for the loss of testis-specific
            poly(A)-binding protein, PABPC2, during mouse spermatogenesis
  JOURNAL   J Reprod Dev 62 (3), 305-310 (2016)
   PUBMED   26971890
  REMARK    GeneRIF: analysis of functional compensation for the loss of mouse
            PABPC2 in spermatogenic cells
REFERENCE   2  (bases 1 to 2586)
  AUTHORS   Kimura M, Ishida K, Kashiwabara S and Baba T.
  TITLE     Characterization of two cytoplasmic poly(A)-binding proteins,
            PABPC1 and PABPC2, in mouse spermatogenic cells
  JOURNAL   Biol Reprod 80 (3), 545-554 (2009)
   PUBMED   19020299
  REMARK    GeneRIF: PABPC2 was present in pachytene spermatocytes and round
            spermatids, whereas elongating spermatids still included PABPC1.
REFERENCE   3  (bases 1 to 2586)
  AUTHORS   Kawahara H, Imai T, Imataka H, Tsujimoto M, Matsumoto K and Okano
            H.
  TITLE     Neural RNA-binding protein Musashi1 inhibits translation initiation
            by competing with eIF4G for PABP
  JOURNAL   J Cell Biol 181 (4), 639-653 (2008)
   PUBMED   18490513
  REMARK    GeneRIF: Poly(A) binding protein (PABP) is identified as an
            Msi1-binding protein, and Msi1 competes with eIF4G for PABP
            binding.
REFERENCE   4  (bases 1 to 2586)
  AUTHORS   de Melo Neto OP, Walker JA, Martins de Sa CM and Standart N.
  TITLE     Levels of free PABP are limited by newly polyadenylated mRNA in
            early Spisula embryogenesis
  JOURNAL   Nucleic Acids Res 28 (17), 3346-3353 (2000)
   PUBMED   10954604
REFERENCE   5  (bases 1 to 2586)
  AUTHORS   Kleene KC and Mastrangelo MA.
  TITLE     The promoter of the Poly(A) binding protein 2 (Pabp2) retroposon is
            derived from the 5'-untranslated region of the Pabp1 progenitor
            gene
  JOURNAL   Genomics 61 (2), 194-200 (1999)
   PUBMED   10534404
REFERENCE   6  (bases 1 to 2586)
  AUTHORS   Kleene KC, Mulligan E, Steiger D, Donohue K and Mastrangelo MA.
  TITLE     The mouse gene encoding the testis-specific isoform of Poly(A)
            binding protein (Pabp2) is an expressed retroposon: intimations
            that gene expression in spermatogenic cells facilitates the
            creation of new genes
  JOURNAL   J Mol Evol 47 (3), 275-281 (1998)
   PUBMED   9732454
REFERENCE   7  (bases 1 to 2586)
  AUTHORS   Paynton BV.
  TITLE     RNA-binding proteins in mouse oocytes and embryos: expression of
            genes encoding Y box, DEAD box RNA helicase, and polyA binding
            proteins
  JOURNAL   Dev Genet 23 (4), 285-298 (1998)
   PUBMED   9883581
REFERENCE   8  (bases 1 to 2586)
  AUTHORS   Kleene KC, Wang MY, Cutler M, Hall C and Shih D.
  TITLE     Developmental expression of poly(A) binding protein mRNAs during
            spermatogenesis in the mouse
  JOURNAL   Mol Reprod Dev 39 (4), 355-364 (1994)
   PUBMED   7893484
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK077154.1, BC051134.1, CN837699.1 and AV259277.1.
            
            On or before May 4, 2006 this sequence version replaced
            XM_988736.1, NM_011033.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-572               AK077154.1         2-573
            573-2113            BC051134.1         553-2093
            2114-2369           CN837699.1         275-530
            2370-2586           AV259277.1         109-325
FEATURES             Location/Qualifiers
     source          1..2586
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 21.14 cM"
     gene            1..2586
                     /gene="Pabpc2"
                     /gene_synonym="Pabp; Pabp+; Pabp2"
                     /note="poly(A) binding protein, cytoplasmic 2"
                     /db_xref="GeneID:18459"
                     /db_xref="MGI:MGI:1349723"
     exon            1..2586
                     /gene="Pabpc2"
                     /gene_synonym="Pabp; Pabp+; Pabp2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2567..2572
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pabpc2"
                     /gene_synonym="Pabp; Pabp+; Pabp2"
     polyA_site      2586
                     /gene="Pabpc2"
                     /gene_synonym="Pabp; Pabp+; Pabp2"
ORIGIN      
        1 gcacgcgccc agcgcaggct ctgtggtcct ggggctctgt ggccagccgt tggggaggtt
       61 ctcatcccct tggttttgat cctctgcgct tgtccgttct gcccctgtct ccgccccagc
      121 ccagcgctgg ccctgctctt ctcgaaggaa ggtgggggcc tgaggcccca cgggctgcag
      181 tgcccagatg aactccagcg acccaggctg tcccatggcc tcgctctatg tgggggacct
      241 gcaccctgat gtgactgagg cgatgctcta tgagaagttc agctctgccg ggcccatcct
      301 ttccatccgg gtatacaggg acgtgatcac acgccgttcc ctgggctatg cttccgtgaa
      361 ctttgagcag cctgctgatg cagagcgagc tttggacacc atgaattttg atgtcatcaa
      421 gggcaagccg gtccgcatca tgtggtctca gcgtgatcca tcacttcgca ggagtggagt
      481 aggcaatgtg ttcattaaaa atttgaacaa gaccattgat aataaagcac tgtatgatac
      541 attctctgct tttggcaata tcctttcctg caaggtggtt agcgatgaga atggctccaa
      601 gggccacgga tttgtacatt ttgagacaga ggaggcagca gaaagagcca tcgagaaaat
      661 gaacgggatg cttctgaatg accgcaaagt gtttgttgga cggtttaagt ctcagaaaga
      721 acgagaagcc gagcttggaa cggggaccaa ggagtttacc aacgtttaca tcaagaactt
      781 tggggaccgc atggatgacg agaccctgaa tggcctcttt ggcaggtttg gacagatctt
      841 aagtgtgaaa gtcatgaccg atgaaggtgg gaaatcgaaa ggattcgggt tcgtcagctt
      901 tgaaaggcat gaagatgcgc agaaagcggt ggacgagatg aatggtaaag aactcaatgg
      961 aaaacacatt tatgttggtc gagcgcagaa aaaagatgac cgtcacacag aacttaaaca
     1021 caaatttgaa caggtgacac aagataagag catcagatat cagggcatta acctttatgt
     1081 gaaaaatctt gatgatggca ttgatgatga acggctccag aaagaatttt ctccatttgg
     1141 aacaatcacc agtacaaagg ttatgacaga gggtggtcgc agtaaaggat tcggttttgt
     1201 gtgtttctcc tccccggaag aagccacaaa agctgtttca gaaatgaatg ggagaattgt
     1261 ggccacgaaa ccactttatg tagctttagc ccagcgcaaa gaagaacgtc aggctcacct
     1321 cactaaccaa tatattcaaa gaatggcaag tgtacgatct gggccgaacc ctgttaaccc
     1381 ctaccaacca gcatcttcca gttactctgt ggccgctgtc ccacagactc agaactgcgt
     1441 tccatgctgc cctagccaaa ttgctcaacc aaggccaagt gctcgctgga ttgctcaggg
     1501 ttcccggcct catccattcc ccaatgtgcc tggtgctatc cacccagctg ctcctagatc
     1561 gtcgttgact actgtaagac caagctcttc acacgttcaa gtcacgacag cacatcgcat
     1621 tactaacaca tcagcacaga taacaggtca gcgtcctgcc ccagcctctt cagctacagc
     1681 gactcctgtt cactcgattc cacagtacaa gtatgctgca ggagtccaga actcccagca
     1741 acatcttaat gcccagctgg cgcaacagcc cgctgtttgc atacagggtc aggaaccttg
     1801 gactgcttcc atgttagtaa ccgctcctca agagccgaag caaatgctgg gtgaaaggct
     1861 attccctctc atccaagcca tgcacccgac tctggctggt aagatcacgg gcatgttgct
     1921 ggacattgat aactcggaac cacttcgtat gcttgaatct ccagtgtctc ggtgttctag
     1981 ggctgaggaa gccgtggcca cactccaagc ccaccaagtt aaagaggctg cccagaaagc
     2041 tgttggcagt acctctggtg tcccaactgt ttaaactgac cagagacctc aaaaaagaaa
     2101 ctcacacttt gcagaagaaa aaaaaaatct aaacattgaa aaaaaacaac attatttaaa
     2161 aaaatagtaa aatataaaat aaataaaaaa ggaaaggaaa ctttgaactt tatgtactga
     2221 gccaatgtca ggtctggtat cttaagccta gcctgattta aaaacagcaa cctcccaaaa
     2281 gaaataggag gatctacaaa ccaatgtttt gtagacccca ggaaaagcat tttcagcaag
     2341 tagaagcatt tagagcatcc ttttaatttt gtaattcttt attgttgaat agctcaaaat
     2401 gttagttcta atagcagaat tgataactga gcaaggaaac atttgaatta taaaattctt
     2461 gctttaataa gaactcacac agtggaaaaa tatcagatat tatttaggta gggataatgt
     2521 gctctatcat tttctttgta ttactctata ttaaattata tattagaata aagaacaact
     2581 agatga
//
