LOCUS       NM_001166365            4331 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus PABIR family member 2 (Pabir2), transcript variant 1,
            mRNA.
ACCESSION   NM_001166365
VERSION     NM_001166365.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4331)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4331)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4331)
  AUTHORS   Sato,T., Fujii,R., Konomi,K., Yagishita,N., Aratani,S., Araya,N.,
            Aono,H., Yudoh,K., Suzuki,N., Beppu,M., Yamano,Y., Nishioka,K. and
            Nakajima,T.
  TITLE     Overexpression of SPACIA1/SAAL1, a newly identified gene that is
            involved in synoviocyte proliferation, accelerates the progression
            of synovitis in mice and humans
  JOURNAL   Arthritis Rheum 63 (12), 3833-3842 (2011)
   PUBMED   22127701
REFERENCE   4  (bases 1 to 4331)
  AUTHORS   Cox,B.J., Vollmer,M., Tamplin,O., Lu,M., Biechele,S.,
            Gertsenstein,M., van Campenhout,C., Floss,T., Kuhn,R., Wurst,W.,
            Lickert,H. and Rossant,J.
  TITLE     Phenotypic annotation of the mouse X chromosome
  JOURNAL   Genome Res 20 (8), 1154-1164 (2010)
   PUBMED   20548051
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK044896.1, AK019480.1 and BB068834.1.
            
            On Oct 29, 2009 this sequence version replaced NM_001166365.1.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript and encodes the shorter protein (isoform 1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC066167.1, SRR17784648.691406.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-774               AK044896.1         2-775
            775-1296            AK019480.1         2-523
            1297-3609           AK019480.1         527-2839
            3610-4312           AK019480.1         2841-3543
            4313-4331           BB068834.1         174-192
FEATURES             Location/Qualifiers
     source          1..4331
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 29.43 cM"
     gene            1..4331
                     /gene="Pabir2"
                     /gene_synonym="4632404H22Rik; Fam122b; SPACIA2"
                     /note="PABIR family member 2"
                     /db_xref="GeneID:78755"
                     /db_xref="MGI:MGI:1926005"
     exon            1..930
                     /gene="Pabir2"
                     /gene_synonym="4632404H22Rik; Fam122b; SPACIA2"
                     /inference="alignment:Splign:2.1.0"
     CDS             833..1600
                     /gene="Pabir2"
                     /gene_synonym="4632404H22Rik; Fam122b; SPACIA2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     synoviocyte proliferation associated in collagen-induced
                     arthritis 2; protein FAM122B; family with sequence
                     similarity 122, member B"
                     /codon_start=1
                     /product="PABIR family member 2 isoform 1"
                     /protein_id="NP_001159837.2"
                     /db_xref="CCDS:CCDS53070.1"
                     /db_xref="GeneID:78755"
                     /db_xref="MGI:MGI:1926005"
                     /translation="MAQEKMDLDFEADTSEGATLRRSNSAPLIHVLSDLSQVFEPYPL
                     RTGRTSTAIMSHHSLEEGLDMMNRETTNEREAQAGMQISQSWDESLSLSDSDFDKPEK
                     LYSPKRIDFTPVSPAPSPTRGFGKQCLSPSLQMFVSSSGMPPSPVLNPRHFSRRSQSP
                     VKCIRPSVLGPLKRKGEMEMESQPKRPFQGTTSMLSTNPAQLSDFSSCSDILDGSSIS
                     SGLSSDSLATGSAPAESPVACSNSCSPFILMDDLSPK"
     exon            931..1009
                     /gene="Pabir2"
                     /gene_synonym="4632404H22Rik; Fam122b; SPACIA2"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1053
                     /gene="Pabir2"
                     /gene_synonym="4632404H22Rik; Fam122b; SPACIA2"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1108
                     /gene="Pabir2"
                     /gene_synonym="4632404H22Rik; Fam122b; SPACIA2"
                     /inference="alignment:Splign:2.1.0"
     exon            1109..1210
                     /gene="Pabir2"
                     /gene_synonym="4632404H22Rik; Fam122b; SPACIA2"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1296
                     /gene="Pabir2"
                     /gene_synonym="4632404H22Rik; Fam122b; SPACIA2"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..1358
                     /gene="Pabir2"
                     /gene_synonym="4632404H22Rik; Fam122b; SPACIA2"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1455
                     /gene="Pabir2"
                     /gene_synonym="4632404H22Rik; Fam122b; SPACIA2"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..4331
                     /gene="Pabir2"
                     /gene_synonym="4632404H22Rik; Fam122b; SPACIA2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4293..4298
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pabir2"
                     /gene_synonym="4632404H22Rik; Fam122b; SPACIA2"
                     /note="hexamer: AATAAA"
     polyA_site      4319
                     /gene="Pabir2"
                     /gene_synonym="4632404H22Rik; Fam122b; SPACIA2"
                     /note="major polyA site"
ORIGIN      
        1 ggctcccatt tctgaagcgt gggaggcaaa agaggcggca ggttatagaa atcaatttga
       61 gctccagagg gtcccgcggg tcattagagc caataagaga tagaagcagc gccgcggtgg
      121 tgcagagggc cgatcccttt tctgagtcgt gcaggcgggc agggaccagg gagtgaaaag
      181 cgccatccct gcgctgaggg gccccgggga ccggggccca gagcatggcg gactggacag
      241 agaccctgag catgtggagg tggggcagcc gaggccgcct ggccagctgt caagtcctca
      301 ttgctagcgc tgcaaaggca gcctctgtaa atgtagccga gccgcgcttg cggtcctagg
      361 cgggaaaaat gacagcttga gttctgccac tgcctagttt cctccccttt cttctcctgt
      421 gcttccacat tctccctcct cctcttttcc catccctgtg ccccttcacc ctgacctttt
      481 tcctcctttc ccacttctat gctctttcat tagtgctatg ccctgcattt ccatctatcc
      541 tttatcaacc cctgtgcctc tttttctttc tcccaccttt gtctttcctc catccccttt
      601 ttcatcctgt caccctccca acaccagctc tatatcctcc tccgcccgcc ctccacatcc
      661 ttcctcatct gcatcctcct ctcctacttt tctccgccct cgctcccaag cctccgccca
      721 ttagcccccg cccccagctg ccagtcccca gcagctcagt cctgcagtga gtccatagca
      781 aagcaccagg agccgagagc actgccggct gtgttgccta gcaagtatcc gaatggctca
      841 ggagaaaatg gatctggatt ttgaggctga cacatctgag ggggccaccc tgagacggtc
      901 caacagtgct cccctgatcc atgtgctcag tgacctttca caggtttttg agccatatcc
      961 acttagaact gggaggacca gtacggcaat tatgagccat catagcttgg aagaaggcct
     1021 ggatatgatg aacagagaaa ctacaaatga aagggaagca caagcaggga tgcagataag
     1081 ccagtcatgg gacgaaagcc tgagcctgag tgatagtgat tttgacaagc cagagaaatt
     1141 atattctccc aaaagaattg acttcactcc agtttctcca gctccttccc caaccagagg
     1201 atttggaaag caatgcttgt cgccatcctt gcaaatgttt gtgagcagca gcgggatgcc
     1261 accgagtcct gttctcaatc caagacattt ttcaaggagg agccagagcc cggtcaagtg
     1321 cattaggccc agtgttcttg gtcctcttaa gagaaaaggg gaaatggaga tggaaagcca
     1381 gcctaagaga cccttccaag gcaccaccag catgctgtct accaatcctg cacaattgtc
     1441 tgatttcagt tcatgttcag atattttgga tggcagtagt atcagcagtg gcttgtcctc
     1501 agactcactg gctacaggca gcgctcccgc agagtctcca gtagcatgct ccaattcatg
     1561 ctctccgttc atcttgatgg atgatctctc acccaagtga cttaaccatt tctgattgag
     1621 tgttttaact gtttcccaca taaaacattc agtgaggaat gcggagaact ttgatccaca
     1681 atggggatta aagtttggca gattgcaacc attccgatga tgctcctatt tctgggcatc
     1741 tctctctaaa gttcaatttt gcaagcagag tcaccttact aacatctgtt tgggctgatc
     1801 tcattttgcg tttgatgact aaatctcaaa tacacatttc tgattgcttg gaggactttt
     1861 tccctagtgc ctcaaagagc acctactttc aaacatttaa ggggagcatt catgcatatt
     1921 ctctataatt gttcttttcc ctagcagtgg caaaacagag ttaatcagaa attctcttgc
     1981 ttgagagatt tataaaaatt ctctgttgac tacatacttt cccatctctt tatttcatgg
     2041 taatattcaa attgtttttg attatatcaa attttcattt tgtctgcatc agctttaaag
     2101 aacattgttt tgtttccctt gcctgtttga cctgctcctt gccatttctc accaagggga
     2161 agaaacccat agttgcttcc atcaccacca ttcttgcttc tttgctattg gaatgtatgc
     2221 agtaacgtct gattttacaa tgtagaatga actagactta caggatgcct gcattagtca
     2281 cctcagggtc ttaggacttt gctatcacag ttgctatttt tctccccaaa cctggtgcct
     2341 taagggatat ataaaatatt gttgatattt ctaggtggtg ttatcaagga gaagaaattc
     2401 ctgccttgac cagatgtgtg gagcatctac aaatgaacga atagttattt acacaaacca
     2461 ctgtacaaaa gcaagcaagc gtccatgaag ctgtcagtgt cttgggtagt attatgaggc
     2521 cttaggtgcc ttggggtaca ttgccgtcct gtagggaata tgtgtcgtag ggtcttgtgg
     2581 aaatggaagc tttctgtatg tgcgtgctat tctgtttgat ttttttttcc tgattccctg
     2641 ttgtccttga gtttgttctg tcatgtggtg accgggtgtt gttggttttt gtgctgtgct
     2701 agagtcagaa ccctcttctt gtccttgttg ccctatagag gtcagtttaa tatcttaata
     2761 tcagttaagg aagctttgag gagctaaaaa ggtcagtact gctgtgccct ctgcttccag
     2821 aagtgttttg agctctaagc agtgtatatg cagtgtgacg taacatatac tctgtaattt
     2881 ttacaaaaga aaactcctga ctaaaatatt taagaaatcc acgtgtgatc tattgtggca
     2941 gtatttatta tgtattacac tagaaatggt gtaatagtgc gatgtctgtg cggttaggtt
     3001 tcttttaatg ttcaacctgg tggatggact atttgtttaa tattcccact agaatcgtgt
     3061 tattaagtga atgtaaaaaa aaaaacaaac agaaaatgat taagcataag tcttttgaaa
     3121 tctaaagtcc ttggaggtgg tttgaaggta tttacagact agaaattagt gagcttgaag
     3181 caaaacctct cttctaatta tcagagacca tcacttagct tgctgcagtt ccattataga
     3241 atcaggtctt aagtttacat tgtaatcact gtcataaaag ctattactgg cctgagttcc
     3301 catgtttctt tagcctgtga aaagctccta atcctccaaa cctaacataa atgtgctgtt
     3361 agaagactcg cccactcctg tgctatttta aagaaacaat tctttgatag cactcggtgt
     3421 atccactctg ttaatgaacc gtattcaaag gctcttgcct tcgtaatgat aagagatgag
     3481 tttttctttc aggagatttg tctgccttca ctcttctgtc ttatttgcct taaagggaca
     3541 ctttgcagtt caaatttaga gtccagattt aggattctta aaaaataatc tttgaaatgt
     3601 gatgatacct aaatttgtgt ttaaaactca atggtaaggt aaaaccagag cagaaaactg
     3661 aaactgtccc aatggtatga tgagatcaaa gaggcaggat tccctttact gtttgagacc
     3721 aactctttta ctaatgtttc taattgagtg ttttcaattt gttctttctc aattccatac
     3781 tcatttaaaa ttcattctga ttactcttgc cccctaccct cctgcatctc tgtcccaacc
     3841 atcagtcacc acttcttctt acagattccc ttatcacatt cttgtctttt tcgttgtaaa
     3901 gtaacctttt attattgttg tcttctatat tgtttaaatg gactagaaag ctaagtttgt
     3961 gcagggattg ttttgaaata aataaaactg gtaatatgct aatccacaga gcagctttgt
     4021 tgacagtacc cctttatttt tatataaagt ctaatatttg aaatgtagtt cttgttataa
     4081 agtaaaattc tttcttccta ttctcatatt atatcatata ttttcagctt ctctttgaaa
     4141 actactacaa aaaaatgaaa ccataataaa atcctataga tactggtttt gcttgactga
     4201 cttataaatc actgttttat gataactgct tttggaataa tagaaagttt tgtgaaatgt
     4261 tgacctagtg tataccctaa aattgtgaat ttaataaagt atatatacgt gtataaaaag
     4321 atggatcgta a
//
