LOCUS       NM_172435               2833 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus purinergic receptor P2Y, G-protein coupled 10
            (P2ry10), transcript variant 1, mRNA.
ACCESSION   NM_172435
VERSION     NM_172435.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2833)
  AUTHORS   Yan,J., Zhang,C., Xu,Y., Huang,Z., Ye,Q., Qian,X., Zhu,L.,
            Huang,G., Wang,X., Jiang,W. and Zhou,R.
  TITLE     GPR34 is a metabolic immune checkpoint for ILC1-mediated antitumor
            immunity
  JOURNAL   Nat Immunol 25 (11), 2057-2067 (2024)
   PUBMED   39358444
  REMARK    Erratum:[Nat Immunol. 2024 Nov;25(11):2167. doi:
            10.1038/s41590-024-02001-w.. PMID: 39375551]
REFERENCE   2  (bases 1 to 2833)
  AUTHORS   Gurusamy,M., Tischner,D., Shao,J., Klatt,S., Zukunft,S.,
            Bonnavion,R., Gunther,S., Siebenbrodt,K., Kestner,R.I.,
            Kuhlmann,T., Fleming,I., Offermanns,S. and Wettschureck,N.
  TITLE     G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4
            T cell migration through autocrine/paracrine mediators
  JOURNAL   Nat Commun 12 (1), 6798 (2021)
   PUBMED   34815397
  REMARK    GeneRIF: G-protein-coupled receptor P2Y10 facilitates
            chemokine-induced CD4 T cell migration through autocrine/paracrine
            mediators.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2833)
  AUTHORS   Wang,X., Cai,J., Lin,B., Ma,M., Tao,Y., Zhou,Y., Bai,L., Jiang,W.
            and Zhou,R.
  TITLE     GPR34-mediated sensing of lysophosphatidylserine released by
            apoptotic neutrophils activates type 3 innate lymphoid cells to
            mediate tissue repair
  JOURNAL   Immunity 54 (6), 1123-1136 (2021)
   PUBMED   34107271
REFERENCE   4  (bases 1 to 2833)
  AUTHORS   Kihara,Y., Maceyka,M., Spiegel,S. and Chun,J.
  TITLE     Lysophospholipid receptor nomenclature review: IUPHAR Review 8
  JOURNAL   Br J Pharmacol 171 (15), 3575-3594 (2014)
   PUBMED   24602016
  REMARK    Review article
REFERENCE   5  (bases 1 to 2833)
  AUTHORS   Rao,S., Garrett-Sinha,L.A., Yoon,J. and Simon,M.C.
  TITLE     The Ets factors PU.1 and Spi-B regulate the transcription in vivo
            of P2Y10, a lymphoid restricted heptahelical receptor
  JOURNAL   J Biol Chem 274 (48), 34245-34252 (1999)
   PUBMED   10567398
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928594.11.
            
            [WARNING] On Feb 25, 2025 this sequence was replaced by
            NM_172435.5.
            
            On Mar 19, 2018 this sequence version replaced NM_172435.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK088234.1, AK041351.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-95                AL928594.11        83700-83794
            96-270              AL928594.11        83925-84099
            271-2833            AL928594.11        96779-99341
FEATURES             Location/Qualifiers
     source          1..2833
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 47.43 cM"
     gene            1..2833
                     /gene="P2ry10"
                     /gene_synonym="5830408N17Rik; Lypsr2; P2Y10"
                     /note="purinergic receptor P2Y, G-protein coupled 10"
                     /db_xref="GeneID:78826"
                     /db_xref="MGI:MGI:1926076"
     exon            1..95
                     /gene="P2ry10"
                     /gene_synonym="5830408N17Rik; Lypsr2; P2Y10"
                     /inference="alignment:Splign:2.1.0"
     exon            96..270
                     /gene="P2ry10"
                     /gene_synonym="5830408N17Rik; Lypsr2; P2Y10"
                     /inference="alignment:Splign:2.1.0"
     exon            271..2833
                     /gene="P2ry10"
                     /gene_synonym="5830408N17Rik; Lypsr2; P2Y10"
                     /inference="alignment:Splign:2.1.0"
     CDS             320..1306
                     /gene="P2ry10"
                     /gene_synonym="5830408N17Rik; Lypsr2; P2Y10"
                     /codon_start=1
                     /product="putative P2Y purinoceptor 10"
                     /protein_id="NP_766023.1"
                     /db_xref="CCDS:CCDS30346.1"
                     /db_xref="GeneID:78826"
                     /db_xref="MGI:MGI:1926076"
                     /translation="MGSNSTSSAESNCNATYLPFQYSLYATTYIFIFIPGLLANSAAL
                     WVLCRFISKKNKAIIFMINLSVADLAHILSLPLRIYYYINRHWPFQRALCLLCFYLKY
                     LNMYASIFFLTCISLQRCLFLLKPFRARNWKRRYDVGISAVIWIVVGTACLPFPILRN
                     AGLANSTDSCFADLGYKQMDAVVLVTMVVIAELAGFVIPVITIACCTWKTTVSLKHPP
                     IAFQGISERKKALRMVFMCAAVFVICFTPYHINFIFYTMVKESIITSCPTVKSTLYFH
                     PFSLCLASLCCLLDPILYYFMASEFRDQLSRHGSSVTRSRLMSRESGSSMVN"
     regulatory      2807..2812
                     /regulatory_class="polyA_signal_sequence"
                     /gene="P2ry10"
                     /gene_synonym="5830408N17Rik; Lypsr2; P2Y10"
                     /note="hexamer: AATAAA"
     polyA_site      2833
                     /gene="P2ry10"
                     /gene_synonym="5830408N17Rik; Lypsr2; P2Y10"
                     /note="major polyA site"
ORIGIN      
        1 ttatcagcag gatatgtgct tgctgcccag agttgtacct ttttactctc atctctttgc
       61 aaatatacaa gactctatcc cagctcagca tcagggattg ttacagaggg aagaaatgtg
      121 attgtctttc agtctagcca gagttcaaag tgaagtataa tgtgatcagc ttccactgtt
      181 acaatagcag tatgaaggat gtgatgcaac tcactgcttg ctaaaggggc tttctataca
      241 gttgacaagg agtagtggat gccacaaaag gagccataat tccacagttt tccttgccaa
      301 acatactgaa atattcaaga tgggcagcaa cagtaccagc agtgctgaga gcaattgcaa
      361 tgccacttat ttgccatttc agtactctct gtatgcaact acctatatct tcatattcat
      421 cccgggtctc ctggctaaca gtgcagccct gtgggttctg tgccgcttca tcagcaagaa
      481 gaacaaggcc atcattttca tgatcaacct ctcagtggca gaccttgctc atatcctgtc
      541 cttacctctt cggatttact attatatcaa tcgtcactgg ccattccaga gggccctttg
      601 cctgctgtgt ttctatctga aatatctcaa catgtatgcc agcatttttt tcttgacatg
      661 cattagcctt cagaggtgcc tctttctcct caaaccattc agagccagaa actggaagcg
      721 taggtacgat gtgggcatca gtgctgtcat ctggattgtt gtagggactg cctgtttgcc
      781 atttcccatc ctgagaaatg ctggcttagc caatagcaca gattcttgct ttgctgatct
      841 tgggtacaaa cagatggatg cagtggttct ggtcaccatg gttgtaattg ctgaacttgc
      901 tggatttgtg attccagtga tcaccattgc atgttgtacc tggaaaacaa ctgtatcctt
      961 gaaacaccca ccaattgctt ttcaagggat tagtgagagg aaaaaagcat tgcggatggt
     1021 tttcatgtgt gctgcagtct tcgttatctg cttcactcct tatcacatta acttcatttt
     1081 ttacaccatg gtaaaggaaa gcatcattac cagttgtccc actgtaaaaa gtaccctgta
     1141 tttccatcct ttttccctat gccttgcaag tctctgttgt cttttggacc caattctgta
     1201 ctatttcatg gcttcagagt ttcgtgacca actatctcgt catggaagct ctgttactcg
     1261 ttctcgtctc atgagcaggg agagtggatc atcaatggtt aactaaaatg agaaaattct
     1321 tcagttagga ttctctttac ctgacattct gtggcattgc ccaaaggcag gaatttccag
     1381 gcaaataatt tctttaactg aaccttggaa atagcagaaa taagttttat tgtgtgatgg
     1441 ttgtggtctc cacagatgat ggaggcataa tgtgaaaaaa tgtgggagta gaaagaaaaa
     1501 tgggatccat gtgcttccaa tttaaaattt atggcattat attagttaca agtcccaatt
     1561 taagttcaag tttttagcag atgtttccat ccaaatataa attgaatgca tatatttaaa
     1621 tttgtcttca gtaaagagaa tagtactgag atgcaaggta tatattaaga tgtacagaag
     1681 aataaatttc ccccatggaa taattttatt tctgaatgga gtaaagattt caagtcttta
     1741 taaaacatta cacacagaca aaatgacaca aaagtttcaa tatgtgaatg aattttagca
     1801 ctgcactctt gctactgaat ggtgtacatg aaaatccacc tcatggatgt tcgtagatgt
     1861 ccatcatttt ctaggttggc agtttgctat gtatttttac aaataatatt tcatcttact
     1921 tttccaatac aagcaacagt aaatgaggag attacaaata caaatgaatg taaatgtaat
     1981 ggcagagagg ttaagcaaca tgtctcacaa ttaacagtta catggcatat acttatgcta
     2041 tttcctctgc ttatattttt atatgtatta ggtcaatact aagtttgagt tgaatgtgga
     2101 ggacacaaac agaagataag cataggaaat agagatagtt ttaacacaat tttcctgtgc
     2161 tcatcgaaaa atctataatt tggggattag catgattctg ggtagagtct tctgtgataa
     2221 atatatcgtc atattagtgt aatcatctat atagtcttga tgagaaaaag ctcaataatt
     2281 cattatttca aaatcaatat tatggctaat ataagccatg caaataacat gaataaaaag
     2341 ctatgaaact gagccgcatt ttagaaaatg taggcttcct tttaaaaatt ctctttttaa
     2401 aaaaattctt acacattact atgtcactaa ataaaatctc aatggttttc agatatcata
     2461 actcacataa ttgcattaga aacagagtat taatcacatt gtgaacaaat atgagagaaa
     2521 tatgtgacct tgtttttttc tgagtgttat ggatactatt ttaagtgttc atatagatga
     2581 tacaaataga acagaacccc catcttctca agttgacaat tcactggtat tttaggtctg
     2641 aaatgaacag agcatagaca tttggtatgc aggcaagaaa aggaagtggt agtacttaga
     2701 acatgcattt gtgtagacta aggaagagga agggaccacc aaaaggagga attaaaagaa
     2761 aatttcttgg ttttggggga atgagatagt tctgtaatta taatgtaata aagtgttttt
     2821 taaaatttgg aaa
//
