LOCUS       NM_001081147            5063 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus oxytocin receptor (Oxtr), transcript variant 1, mRNA.
ACCESSION   NM_001081147 XM_006505723 XM_144956
VERSION     NM_001081147.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5063)
  AUTHORS   Harima,Y., Tsurutani,M., Yamada,S., Uchida,S., Inada,K.,
            Hagihara,M., Irie,S., Shigeta,M., Abe,T., Inoue,Y.U., Inoue,T. and
            Miyamichi,K.
  TITLE     Parallel labeled-line organization of sympathetic outflow for
            selective organ regulation in mice
  JOURNAL   Nat Commun 15 (1), 10478 (2024)
   PUBMED   39658565
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5063)
  AUTHORS   Saito,Y., Mogi,K. and Kikusui,T.
  TITLE     Oxytocin receptor control social information about fear expression
            of others in mice
  JOURNAL   Psychoneuroendocrinology 169, 107150 (2024)
   PUBMED   39121686
  REMARK    GeneRIF: Oxytocin receptor control social information about fear
            expression of others in mice.
REFERENCE   3  (bases 1 to 5063)
  AUTHORS   Zhang,Y., Wang,M., Zhu,Q., Guo,Y., Liu,B., Li,J., Yao,X., Kong,C.,
            Zhang,Y., Huang,Y., Qi,H., Wu,J., Guo,Z.V. and Dai,Q.
  TITLE     Long-term mesoscale imaging of 3D intercellular dynamics across a
            mammalian organ
  JOURNAL   Cell 187 (21), 6104-6122 (2024)
   PUBMED   39276776
REFERENCE   4  (bases 1 to 5063)
  AUTHORS   Wolf,D., Hartig,R., Zhuo,Y., Scheller,M.F., Articus,M., Moor,M.,
            Grinevich,V., Linster,C., Russo,E., Weber-Fahr,W., Reinwald,J.R.
            and Kelsch,W.
  TITLE     Oxytocin induces the formation of distinctive cortical
            representations and cognitions biased toward familiar mice
  JOURNAL   Nat Commun 15 (1), 6274 (2024)
   PUBMED   39054324
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5063)
  AUTHORS   Hayashi,H., Shimizu,K., Nakamura,K., Nishimori,K. and Kondo,Y.
  TITLE     The bilevel chamber revealed differential involvement of
            vasopressin and oxytocin receptors in female mouse sexual behavior
  JOURNAL   PLoS One 19 (6), e0304703 (2024)
   PUBMED   38900750
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5063)
  AUTHORS   Wesley,V.J., Hawtin,S.R., Howard,H.C. and Wheatley,M.
  TITLE     Agonist-specific, high-affinity binding epitopes are contributed by
            an arginine in the N-terminus of the human oxytocin receptor
  JOURNAL   Biochemistry 41 (16), 5086-5092 (2002)
   PUBMED   11955056
REFERENCE   7  (bases 1 to 5063)
  AUTHORS   Arend,L.J., Smart,A. and Briggs,J.P.
  TITLE     Metanephric rat-mouse chimeras to study cell lineage of the nephron
  JOURNAL   Dev Genet 24 (3-4), 230-240 (1999)
   PUBMED   10322631
REFERENCE   8  (bases 1 to 5063)
  AUTHORS   Gross,G.A., Imamura,T., Luedke,C., Vogt,S.K., Olson,L.M.,
            Nelson,D.M., Sadovsky,Y. and Muglia,L.J.
  TITLE     Opposing actions of prostaglandins and oxytocin determine the onset
            of murine labor
  JOURNAL   Proc Natl Acad Sci U S A 95 (20), 11875-11879 (1998)
   PUBMED   9751758
REFERENCE   9  (bases 1 to 5063)
  AUTHORS   Kubota,Y., Kimura,T., Hashimoto,K., Tokugawa,Y., Nobunaga,K.,
            Azuma,C., Saji,F. and Murata,Y.
  TITLE     Structure and expression of the mouse oxytocin receptor gene
  JOURNAL   Mol Cell Endocrinol 124 (1-2), 25-32 (1996)
   PUBMED   9027321
REFERENCE   10 (bases 1 to 5063)
  AUTHORS   Kaluz,S., Kaluzova,M. and Flint,A.P.
  TITLE     Heterogeneity in the third intracytoplasmic region of the oxytocin
            receptor-encoding gene
  JOURNAL   Gene 172 (2), 313-314 (1996)
   PUBMED   8682324
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153594.15.
            
            On or before Aug 1, 2022 this sequence version replaced
            XM_006505723.3, NM_001081147.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR12282455.28207336.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-218               AC153594.15        165649-165866       c
            219-368             AC153594.15        165061-165210       c
            369-1426            AC153594.15        163906-164963       c
            1427-5063           AC153594.15        148712-152348       c
FEATURES             Location/Qualifiers
     source          1..5063
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 52.27 cM"
     gene            1..5063
                     /gene="Oxtr"
                     /gene_synonym="OTR"
                     /note="oxytocin receptor"
                     /db_xref="GeneID:18430"
                     /db_xref="MGI:MGI:109147"
     exon            1..218
                     /gene="Oxtr"
                     /gene_synonym="OTR"
                     /inference="alignment:Splign:2.1.0"
     exon            219..368
                     /gene="Oxtr"
                     /gene_synonym="OTR"
                     /inference="alignment:Splign:2.1.0"
     exon            369..1426
                     /gene="Oxtr"
                     /gene_synonym="OTR"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..5063
                     /gene="Oxtr"
                     /gene_synonym="OTR"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5043..5048
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Oxtr"
                     /gene_synonym="OTR"
                     /note="hexamer: AATAAA"
     polyA_site      5063
                     /gene="Oxtr"
                     /gene_synonym="OTR"
                     /note="major polyA site"
ORIGIN      
        1 actgtggtgc aacttccccg gtggcaaggc aactttgggc taacctgcag tctcgcttca
       61 agtggctggg tcctgcgcac tgtggcgaca ggatgcctag gacctacctg taggaccctc
      121 aggttcggag ggaaggatct ggcgcgtttc acgtctctgg ttccgggagg tgctcagggt
      181 gtaccgagag agactgaaaa gtgacagctt ggacgaaggc agagcggctg actctttcct
      241 gggacctaag cgcaggggca tctgcagaag ctcaaaggag gtacctcaaa ctaggattcc
      301 tacggtcacc accgagaagt caccaccact gcgcagctcc aaggctgggc tggtgcactg
      361 agactcaggg agaggacagg caggtcagtg ccagagtgct cccatagaca cctggactga
      421 gcgccgggcc ccgccccacg tgccacactt taaagagcct caaggccggg tgctccctca
      481 gggtcgcggt cgcggtcgcg gttggtcatg gagggcacgc ccgcagccaa ctggagtatc
      541 gagttggacc tcgggagtgg agtgccacca ggggcggagg gtaacctcac ggccgggccg
      601 ccacgacgca acgaggccct ggcgcgcgtg gaggtggcgg tcctgtgtct catactgttc
      661 ctggctctga gtggcaacgc gtgcgtgctg ctggcgctgc gtacgacgcg ccacaagcac
      721 tcgcgcctct tctttttcat gaagcacctg agcatcgccg acctggtggt ggccgtgttc
      781 caggttctcc cgcagctgct gtgggacatc accttccgct tctacgggcc cgacctgctg
      841 tgtcgtctgg tcaaatactt gcaggtggtg ggcatgttcg cctccaccta cctgctgttg
      901 ctgatgtcgc tcgaccgctg cctggccatc tgccagccgc tgcgctcact gcgccgccga
      961 accgaccgcc tggcggtgct ggcgacgtgg ctcggctgcc tggtggccag cgtgccgcag
     1021 gtgcacattt tctcgctgcg cgaagtggcg gacggcgtct tcgattgctg ggcggtcttc
     1081 atccagccct ggggacccaa ggcctacgtc acgtggatca cgctcgccgt ctacattgta
     1141 ccggtcatcg tgctggccgc ctgctatggt ctcatcagct tcaagatctg gcagaatctg
     1201 cgactcaaga cggcagccgc ggcggcagct gccgagggga gtgacgcagc cggtggagct
     1261 ggccgtgcgg cgttggcacg ggtcagtagt gtcaagctta tctccaaggc caaaatccgc
     1321 acagtgaaga tgaccttcat cattgttctg gccttcatcg tgtgctggac gcctttcttc
     1381 ttcgtgcaga tgtggagcgt ctgggacgtc aatgcgccca aagaagcttc tgccttcatc
     1441 attgccatgc tcttggccag cctcaacagc tgctgcaacc catggatcta catgctcttc
     1501 acgggccatc tcttccacga actcgtgcag cgcttcctct gctgctctgc tcggtacctg
     1561 aagggcagcc ggcctggaga gacgagcatt agcaagaaaa gcaactcctc caccttcgtc
     1621 ctgagtcgtc gcagctcgag tcagaggagc tgttctcaac catcctcggc atgagccata
     1681 ggcctggccc accaggccag ccgctgggtg gtgtagccgc cgatcttccc ctctggtggc
     1741 tgtgcatgga gctgtatatg gtgcctattg attggtttgc atccctcctg tccttgggct
     1801 ggttagattc tgtgtcatat tctgacttgg ggtagggaaa tgtctccatg ggagatgaca
     1861 gggtcactca gccatcagag gatcacctgg actcccacct atttctacta ccctgactca
     1921 agtgttcctg ggcagtgggt agattctcct gcacctcact tctgtcccct ccaccccttg
     1981 tttatcctgg tatcttgtga aagacggcac acctaggatt ggtgaccagt tacctgagga
     2041 agtccagtgg gatgagacaa ggagtgggaa atgaggctgc agacgcagag tggtgctaat
     2101 ttccttctga cctgagttgt gtggacagat cttagcatcc ttaggacatc ccagaaagca
     2161 tttggagctg gaaactgagc cgtgaagcca cctggctctg gaaggaatga gaacgagggc
     2221 tgaaaggttg aagatgttgt tgcttgacaa acatttggga aggaaaagga aatgagagcc
     2281 acccaggaca gacgagggag gagagctgtc tgtacacaca ctgatccatg catatgtgat
     2341 cctaggagcg ctcacacaca tgcaagtagt ctctctctct ctctctctct ctctctcccc
     2401 ccccatctct tcccagagct gacagatgag aagcaaggtt agtgtcagat caatgtacag
     2461 agatcgttta tatttcctta tactgctggt gaccaatggg aaggtgaagt aaggagcgcc
     2521 cacccataaa agtcccagac tgagtaaagg aaggctaggg ctaacagaga aaacagagca
     2581 agcccatgcc ctgaaggctg caaataggca cttggggaac gttaaggaga ctagataaat
     2641 ggggccacct tgtgcttgtg aatcagagac gtaatattat tggacagatt tgatgtaatc
     2701 ctcatcaaat tcctagctgg cttctgcaga aattgataaa gtgatcctaa aattcccaag
     2761 gagatgggga ttggggtgct taagatgctt aggaatttgt gatgggtgca caattctgag
     2821 aacgtattta aaattaataa agcaaactcc agcggctgag gagatggctc actcagagaa
     2881 gtaaatgtgt gctgagtgag tgtaaggacc caacttcagc acccagcatc ccatccatgt
     2941 agacaccagg ctcagtgagc cttaacctca gccctggggt gaggtggggg tgacagatga
     3001 tcctgtcaga gacttgcaag gcagccagcc tagcagactt caagcaactt caagttcagc
     3061 aagagactct atctcaagac aaataactca gtaaataaaa ataaggtgga gagtgatgga
     3121 agaaaacacc agaagtcgac ctttggtctc tacacgtata tatggctata cagcatacac
     3181 acacttacat gcaagcagac acacacacct atgcatacat gcatgcacac acacacacac
     3241 acacacacac acacacatgc acacgcacgc acaaaaccat taaactatat acacttgaaa
     3301 atgtgaaaaa agttcaagag ccgagttctg ggaaaaccac aatgatggat ggacttcttg
     3361 acctatcttc cttgagtgca gtttcccatg tgactcacca cctccgagtg tctgcagcag
     3421 aggcgggctc tgttctggcc tgtggaagca gtgagcaccc ccatctggct ttgccgaagg
     3481 cccgaaggcc cgagggatgc tccaccattg tggcctgtct tctttagaac agcacttccc
     3541 caggagtctt aaaggttttg tttatcagat aagcatgctc tcaaatgtcc tctcagtctt
     3601 gaggacagga tatgagtctg tctcagaaat acctttgacc attaaatata ggtcacaact
     3661 gaatagtggc tttctgcctg tgtctggtca ctgtgcactc tggagtccct ttgaaatacc
     3721 cagacttaat tctggactta ctgaaatata tcaagggcgc ttccaaaaag cctagaatct
     3781 gtagatccac tttgttaact gcccacctcc catacttctg aacacatttt cttctgctat
     3841 gctgcagtat ttgcccaaac ccatacatgt acctgtatgc gcacacatgc acaaatgaat
     3901 atgaaacagt gcagttgagt gtttaggaag aaggaagcca cgtgctacag tgcccatgtt
     3961 caacatccac aacttagggc aagctggttg acaccagctg gagataggag gcagtgtcat
     4021 ttttggaccc agggacatta accctcatgc atacagtgtc acaccagctt gtcccagctc
     4081 tttgagaagc tagcacgatt ctgctttagg gtgtctgcct atgtcctaga ccatcctgct
     4141 cgcctgggtg atggcaggca tggcagtagc ctgttagcat ctgtgtcttg caggtgctct
     4201 gattccctgc tatccacaga gaagttgcta tccttagggc caaaaggtgt cactaggggt
     4261 caagggaagg agtgactcag atattctgac catggacaca gtgttccgga gagccccaga
     4321 gggcatagaa acctgctgtt gtcagtctcc atgaaagctc tagctggtac cttgggtctt
     4381 gtcctgacac ccgtatctgt gacataagtg acagttgact tcaccagcaa cattggattg
     4441 gcaccttact gtcctaatcg cacaggaaaa aatttttttt ttatcatttt tttcaattgt
     4501 tatctcccca atgaaagctg aggatctcta ggggttcaaa acacccactc ccagtcctgt
     4561 gacctgtgtt cttcttcctc agattccaca cctgacatcc ccagtgcccc ttccattttc
     4621 cagcctgttt acaatccatg tgcagggttg aaagttgtgt taaactggag ctgaatgttc
     4681 tggaatgttt cgttgttctg accatgaaga gtcagtgtgc aaactgtgag agtcacttag
     4741 gccctgccag aaaagagtct ccatttaaaa ctctgtgtct ccttttggga caaatctgag
     4801 ccatcacttc agagagcaca ggaggatgtc agtgcaggct gccggctgat ggtcccagct
     4861 ttcagcatgt acctttggta ttcaattgca atgagatgcc cctcagcaca cagtgtgaac
     4921 tccttgataa tgtgatttca tggacactcg tgtggtgccc agtgtcccct gcgtctggtg
     4981 agtgacacag ccaattctga aatgcctgct ttaccagctg ctgctccata aatggtgcac
     5041 ttaataaaca ttttttttct gta
//
