LOCUS       NM_181859               1755 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus 3-oxoacid CoA transferase 2B (Oxct2b), mRNA; nuclear
            gene for mitochondrial product.
ACCESSION   NM_181859 XM_910338
VERSION     NM_181859.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1755)
  AUTHORS   Lu,Y., Oura,S., Matsumura,T., Oji,A., Sakurai,N., Fujihara,Y.,
            Shimada,K., Miyata,H., Tobita,T., Noda,T., Castaneda,J.M.,
            Kiyozumi,D., Zhang,Q., Larasati,T., Young,S.A.M., Kodani,M.,
            Huddleston,C.A., Robertson,M.J., Coarfa,C., Isotani,A.,
            Aitken,R.J., Okabe,M., Matzuk,M.M., Garcia,T.X. and Ikawa,M.
  TITLE     CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched
            genes dispensable for male fertility in micedagger
  JOURNAL   Biol Reprod 101 (2), 501-511 (2019)
   PUBMED   31201419
REFERENCE   2  (bases 1 to 1755)
  AUTHORS   Somboonthum,P., Ohta,H., Yamada,S., Onishi,M., Ike,A., Nishimune,Y.
            and Nozaki,M.
  TITLE     cAMP-responsive element in TATA-less core promoter is essential for
            haploid-specific gene expression in mouse testis
  JOURNAL   Nucleic Acids Res 33 (10), 3401-3411 (2005)
   PUBMED   15951513
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1755)
  AUTHORS   Onishi,M., Yasunaga,T., Tanaka,H., Nishimune,Y. and Nozaki,M.
  TITLE     Gene structure and evolution of testicular haploid germ
            cell-specific genes, Oxct2a and Oxct2b
  JOURNAL   Genomics 83 (4), 647-657 (2004)
   PUBMED   15028287
  REMARK    GeneRIF: Oxct2a and Oxct2b are testicular haploid germ
            cell-specific genes
REFERENCE   4  (bases 1 to 1755)
  AUTHORS   Tanaka,H., Iguchi,N., Miyagawa,Y., Koga,M., Kohroki,J. and
            Nishimune,Y.
  TITLE     Differential expression of succinyl CoA transferase (SCOT) genes in
            somatic and germline cells of the mouse testis
  JOURNAL   Int J Androl 26 (1), 52-56 (2003)
   PUBMED   12534938
REFERENCE   5  (bases 1 to 1755)
  AUTHORS   Tanaka,H., Kohroki,J., Iguchi,N., Onishi,M. and Nishimune,Y.
  TITLE     Cloning and characterization of a human orthologue of
            testis-specific succinyl CoA: 3-oxo acid CoA transferase (Scot-t)
            cDNA
  JOURNAL   Mol Hum Reprod 8 (1), 16-23 (2002)
   PUBMED   11756565
REFERENCE   6  (bases 1 to 1755)
  AUTHORS   Koga,M., Tanaka,H., Yomogida,K., Nozaki,M., Tsuchida,J., Ohta,H.,
            Nakamura,Y., Masai,K., Yoshimura,Y., Yamanaka,M., Iguchi,N.,
            Nojima,H., Matsumiya,K., Okuyama,A. and Nishimune,Y.
  TITLE     Isolation and characterization of a haploid germ cell-specific
            novel complementary deoxyribonucleic acid; testis-specific
            homologue of succinyl CoA:3-Oxo acid CoA transferase
  JOURNAL   Biol Reprod 63 (6), 1601-1609 (2000)
   PUBMED   11090426
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ047771.1, AB049996.1 and BC113758.1.
            
            On Nov 16, 2007 this sequence version replaced NM_181859.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB049996.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-44                CJ047771.1         2-45
            45-482              AB049996.1         35-472
            483-1702            BC113758.1         466-1685
            1703-1755           AB049996.1         1693-1745
FEATURES             Location/Qualifiers
     source          1..1755
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 57.38 cM"
     gene            1..1755
                     /gene="Oxct2b"
                     /gene_synonym="Scot-t2"
                     /note="3-oxoacid CoA transferase 2B"
                     /db_xref="GeneID:353371"
                     /db_xref="MGI:MGI:2664115"
     exon            1..1753
                     /gene="Oxct2b"
                     /gene_synonym="Scot-t2"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..1604
                     /gene="Oxct2b"
                     /gene_synonym="Scot-t2"
                     /EC_number="2.8.3.5"
                     /note="succinyl CoA:3-oxoacid CoA-transferase;
                     testis-specific succinyl-CoA:3-oxoacid CoA-transferase 2;
                     succinyl-CoA:3-ketoacid coenzyme A transferase 2B,
                     mitochondrial"
                     /codon_start=1
                     /product="succinyl-CoA:3-ketoacid coenzyme A transferase
                     2B, mitochondrial precursor"
                     /protein_id="NP_862907.2"
                     /db_xref="CCDS:CCDS18609.1"
                     /db_xref="GeneID:353371"
                     /db_xref="MGI:MGI:2664115"
                     /translation="MAALRLLAWALPRGVSALRPRPALPHRLIRRYVSDRSGSVHFYT
                     DPVKAVEGVKDGSTVMLGGFGLCGIPENLIGALKTKGVKDLKIVSSNVGVDDFGLGIL
                     LASKQVRRVVCSYLGENALCEKLYLAGELELEMTPQGTLAERIRAGGTGVPAFYTPTG
                     YGTLVQEGGSPIRYAPDGHLITLSEPREVREFQGRFYLLEHAIRADFALIKGWKADRS
                     GNVIFRGSARNFNVPMCKAADISVVEVEEIVDVGTFAPEDIHIPNIYVDRVIKGPKFE
                     KRIERLTTRDSKPAPGSKDNDPSRTRIIKRAALEFQDGMYANLGIGIPVLASNYISPK
                     MTVYLHSENGILGLGPFPLKNEVDADVINAGKQTVTVVPGGCFFASDDSFAMIRGGHL
                     QLTMLGAMQVSQYGDLANWMVPGKKVKGMGGAMDLVSSKKTRVVVTMEHCTKTKQPKI
                     LKKCTMPLTGKRCVDLIITEKAVFEVNHSKGLTLVELWEGSSVDDIKATTACSFAVSP
                     NLKPMQQIKLDA"
     regulatory      1735..1740
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Oxct2b"
                     /gene_synonym="Scot-t2"
                     /note="hexamer: ATTAAA"
     polyA_site      1753
                     /gene="Oxct2b"
                     /gene_synonym="Scot-t2"
                     /note="major polyA site"
ORIGIN      
        1 ctctctctgt cccggagctg ggagcccgat ggctgtggaa gatggcggcg ctgaggcttc
       61 tggcctgggc gctcccacgt ggggtctctg ctctccgccc acgacctgcg ctgccccacc
      121 gccttatccg ccgctatgtt tcggaccgca gcgggagtgt ccatttctac acggacccgg
      181 tgaaggcggt ggagggcgtc aaggatgggt cgaccgtcat gctcgggggc ttcgggctct
      241 gcggcatccc cgagaacctg atcggtgcgc tgaagaccaa gggcgtgaag gacctgaaga
      301 tcgtcagcag caacgtgggc gtggacgact tcggcctggg catcttgctg gcctccaagc
      361 aggtcaggcg cgtggtgtgc tcctacctgg gggagaacgc gctctgcgag aagctctacc
      421 tggcgggcga gctggaactg gagatgacgc cgcagggaac tctggccgag cgcatccgcg
      481 cgggtggcac tggcgtgccc gccttctaca cgcccacagg ctacggaacg ctggtgcagg
      541 aagggggctc tccaatccgg tacgcgcccg atggccacct gattactcta agtgagccgc
      601 gagaagtacg cgagtttcag ggccgcttct acctgctaga gcacgctatc cgcgctgact
      661 tcgcactgat caagggctgg aaagccgacc gctcgggcaa cgtgatcttc agaggcagcg
      721 cgcgcaactt caatgtgccc atgtgcaagg ccgcggacat ctcggtggta gaagtggagg
      781 agatcgtgga cgttggtact ttcgccccgg aagacatcca catccccaac atctatgtgg
      841 accgcgtgat caaggggccg aagttcgaga agcgcatcga gcgcctaacc acacgtgaca
      901 gcaagcccgc gcccgggagc aaagacaatg acccttccag gacgcgcatc atcaagcgcg
      961 cggctctgga gttccaggac ggcatgtatg ccaatctggg catcgggatc cctgtcttgg
     1021 cgagcaacta catcagcccc aagatgaccg tctacctgca cagtgaaaac ggaatcctgg
     1081 gcttgggccc gttccctttg aaaaatgagg tagatgccga cgtcatcaac gcaggcaagc
     1141 agacagtgac ggtggttccc gggggctgtt tcttcgccag cgatgactct tttgccatga
     1201 ttcgtggcgg acacctccaa ctgaccatgc ttggggccat gcaagtttct caatacggcg
     1261 acctggccaa ctggatggtg ccaggcaaga aggtgaaggg catgggtggg gccatggact
     1321 tggtgtctag taaaaagacc agagtggtag tcaccatgga acactgtacc aagacaaagc
     1381 agcccaaaat cttgaagaaa tgcaccatgc cgttgactgg caagcgctgc gtggacctca
     1441 tcatcactga gaaggcggtg tttgaagtga accactcaaa ggggctgacg ctggtggagc
     1501 tgtgggaggg ctcgtcggta gatgacatca aggccaccac agcctgttca tttgctgtgt
     1561 cccccaacct caagcccatg cagcagatta aacttgatgc ttgaggagcc ctccagggct
     1621 gattttccag ttagtgacaa ctggacatcc ttagcagcac ctgaccactg tgccacactg
     1681 gctcctccgc cttccttctg ctagatggtg tctagtgaga gccatgtgac cttaattaaa
     1741 aaccctaacc tgaaa
//
