LOCUS       NM_027136               2642 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus candidate tumor suppressor in ovarian cancer 2
            (Ovca2), mRNA.
ACCESSION   NM_027136
VERSION     NM_027136.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2642)
  AUTHORS   Corbo,J.C. and Cepko,C.L.
  TITLE     A hybrid photoreceptor expressing both rod and cone genes in a
            mouse model of enhanced S-cone syndrome
  JOURNAL   PLoS Genet 1 (2), e11 (2005)
   PUBMED   16110338
  REMARK    Erratum:[PLoS Genet. 2008 Jan;4(1):e18]
REFERENCE   2  (bases 1 to 2642)
  AUTHORS   Chen,C.M. and Behringer,R.R.
  TITLE     Cloning, structure, and expression of the mouse Ovca1 gene
  JOURNAL   Biochem Biophys Res Commun 286 (5), 1019-1026 (2001)
   PUBMED   11527402
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL603905.19.
            
            On Mar 21, 2007 this sequence version replaced NM_027136.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK033511.1, BC060159.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-197               AL603905.19        98307-98503         c
            198-2642            AL603905.19        95638-98082         c
FEATURES             Location/Qualifiers
     source          1..2642
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 45.76 cM"
     gene            1..2642
                     /gene="Ovca2"
                     /gene_synonym="9030414M07Rik"
                     /note="candidate tumor suppressor in ovarian cancer 2"
                     /db_xref="GeneID:246257"
                     /db_xref="MGI:MGI:2179725"
     exon            1..197
                     /gene="Ovca2"
                     /gene_synonym="9030414M07Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             14..691
                     /gene="Ovca2"
                     /gene_synonym="9030414M07Rik"
                     /note="candidate tumor suppressor OVCA2; ovarian
                     cancer-associated gene 2 protein homolog; ortholog of
                     human candidate tumor suppressor in ovarian cancer 2
                     OVCA2"
                     /codon_start=1
                     /product="esterase OVCA2"
                     /protein_id="NP_081412.1"
                     /db_xref="CCDS:CCDS25041.1"
                     /db_xref="GeneID:246257"
                     /db_xref="MGI:MGI:2179725"
                     /translation="MAARQTLRVLCLAGFRQSERGFREKTGALRKTLRGRAELVCLSG
                     PHPVPEAAAPEGSCPDSGPCSPEEQPRGWWFSEEEADVFSALEESTVCRGLQEALETV
                     ARALDTLGPFDGLLGFSQGAALAAYVCALGQAGDPRFPLPRFIILVSGFCPRGLKEPI
                     LQSPMSLPSLHVFGDTDRVIPSQESMQLASRFLGAVTLTHSGGHFIPAAASQRQAYLK
                     FLDQFAE"
     exon            198..2642
                     /gene="Ovca2"
                     /gene_synonym="9030414M07Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      864..869
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ovca2"
                     /gene_synonym="9030414M07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      889
                     /gene="Ovca2"
                     /gene_synonym="9030414M07Rik"
                     /note="major polyA site"
     regulatory      2479..2484
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ovca2"
                     /gene_synonym="9030414M07Rik"
                     /note="hexamer: TATAAA"
     polyA_site      2484
                     /gene="Ovca2"
                     /gene_synonym="9030414M07Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtcggtctgc agtatggcgg cacggcagac cctgcgagtg ctgtgtctag ccggcttccg
       61 gcagagcgag cggggcttcc gtgagaagac cggagcgctg aggaagacgc tgcggggtcg
      121 ggcagagctt gtgtgcctca gcggacctca cccggtcccc gaggcagcgg ctcccgaggg
      181 ttcgtgtcca gactcggggc cctgttctcc ggaggagcag cctcgaggct ggtggttttc
      241 tgaggaggaa gccgatgttt tctctgctct ggaagagtcc acagtgtgca ggggtctgca
      301 ggaggccctg gaaacggtgg cacgggccct tgacacgctg gggccgtttg atggacttct
      361 tggcttcagc cagggggctg cactagcagc ttatgtgtgt gccctgggcc aggcaggcga
      421 tcctcgcttc cccttgccaa gatttattat acttgtgtcg gggttctgtc cccgaggcct
      481 taaggaacct atcttgcaga gccccatgtc actgccttca cttcatgttt ttggggatac
      541 tgatcgagtc atcccttctc aggagagtat gcaattggct agccgattcc ttggagccgt
      601 caccctcacc cactccggtg gtcacttcat tccagcagct gcatctcagc gtcaggccta
      661 ccttaagttc ttggaccagt ttgcagaatg aaggatggac aaatgtctcc gcactgctcc
      721 cactttgtcc agcagctctc ccctgtctcc tcaccatggc tagttaagac aactgtcagt
      781 tctcaggaca cacataagcc cagagagcct gtgagaagac aggggtgggc aggcaggggc
      841 tggcacccct gtgactgaca gacaataaag cgatgcttta gatgttgaat gcctttctcc
      901 tgctgccccg atcctggggc agcaccaaac caaacccaag gacacatttt tggtggaagt
      961 catttattgt tttgtatctt taaattcggc ttattgtgtg tatgggtgca gacttgtgga
     1021 gatcagagga taagtgcggg gagttgattc aaccatgtgg gttctttctg agctctgatc
     1081 atttgacttg gcaagtcatg cctctacctg ctgagccatg tcaccatcct tttgtggaag
     1141 tttaagtccc agactgaaga agctagatat cttggtcact tagaatcaga aagttttacg
     1201 tttgaggagt ttggggaaag aaaacacttg gcaaggctct gcttggctcc atctgctttt
     1261 aggtttccta catcctggtc cctggcttgg ccattgcttt ctcttccata actgttccat
     1321 ccccctctga actctgagct tgaagacttg ggtagtacca tatgttgggt agaggccaaa
     1381 gacagcacag agtaacctgc cttttcctaa tgaagccatc ttcagggttt ctgagattac
     1441 tgctattcat aattgatgat gctaattatt gatatgttga gaaagccaaa gcttaagtag
     1501 cctgctcagc ttaacttctt gccatttttc ttctcacttc cagtgcccaa tcttgccaca
     1561 cacataggca cgctgctttc tgacttctgc ctctgaaaga cagtttttcc aagatatcac
     1621 aaggtactta cctagtccca caccacaata tcttctaggg agcttagtca ctgagcagga
     1681 gttggagttg gccagttact cccaagtcat tcttataccc agagttatat gttcttgaca
     1741 cacaagtgtt tcaaggtata catcagagaa atggttctgt ggttaaggac atgggctgct
     1801 ttttcaaagg acccaggttc gggctccagc atccacaatg tagctcacaa acatctatag
     1861 ctcttagttc cagaggctct agtcccaggt cccagggttg tacatgatat gtgtttaaaa
     1921 agtcaatgac ccaatggcca tggtggtaca tgcaggcaga ggtagaggac agtctagtct
     1981 aaaaacaacc agttagtggt ggcacgtgcc tttcatccca gcactggcag agacaggcag
     2041 atctgagact gagcttatcc tagtctacag atggagttcc aggacagaga gggctacaca
     2101 ggaacgctct ctgtaacctc tgttagatga ccaaggcaga gccttgccat gtattctctt
     2161 gccccgaact ccacttacat agaagtctga ctcagttaca aaggcctctg gcttctttag
     2221 ggctcaagat ttccaccaaa agacagtgag atggctcagc aggttaaagg cactgactgc
     2281 tagctaacac atgccatctc atacacacta aacattttaa aatttcacga aaggatagac
     2341 tggaattata ccccaaagtc ccatgtactg atttgagatc cctttttaac agcttgggtg
     2401 ggggattggt ctctgtgcct tgttcttgcc ttacagtgat tgcttccttg acaaaaggag
     2461 attgaacacg tggaatttta taaacccttt ggtctatttg cttttctgta actaattggt
     2521 gggtttgcaa gttagtactc agaccactgg cagtcatagg cagccccctg tgtcagctcc
     2581 aagctggggg acaggatgac ctgtacttgg tagccctata aataaaggca aaggttcatg
     2641 tg
//
