LOCUS       NM_001025614            8043 bp    mRNA    linear   ROD 14-MAY-2024
DEFINITION  Mus musculus OTU domain containing 7B (Otud7b), transcript variant
            2, mRNA.
ACCESSION   NM_001025614 XM_110475 XM_619935
VERSION     NM_001025614.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8043)
  AUTHORS   Varner,L.R., Chaya,T., Maeda,Y., Tsutsumi,R., Zhou,S., Tsujii,T.,
            Okuzaki,D. and Furukawa,T.
  TITLE     The deubiquitinase Otud7b suppresses cone photoreceptor
            degeneration in mouse models of retinal degenerative diseases
  JOURNAL   iScience 27 (4), 109380 (2024)
   PUBMED   38510130
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8043)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 8043)
  AUTHORS   Du,B.B., Zhang,J.L., Kong,L.Y., Shi,H.T., Zhang,D.H., Wang,X.,
            Yang,C.L., Li,P.C., Yao,R., Liang,C., Wu,L.M. and Huang,Z.
  TITLE     Ovarian Tumor Domain-Containing 7B Attenuates Pathological Cardiac
            Hypertrophy by Inhibiting Ubiquitination and Degradation of
            Kruppel-Like Factor 4
  JOURNAL   J Am Heart Assoc 12 (24), e029745 (2023)
   PUBMED   38084712
  REMARK    GeneRIF: Ovarian Tumor Domain-Containing 7B Attenuates Pathological
            Cardiac Hypertrophy by Inhibiting Ubiquitination and Degradation of
            Kruppel-Like Factor 4.
REFERENCE   4  (bases 1 to 8043)
  AUTHORS   Harit,K., Bhattacharjee,R., Matuschewski,K., Becker,J., Kalinke,U.,
            Schluter,D. and Nishanth,G.
  TITLE     The deubiquitinating enzyme OTUD7b protects dendritic cells from
            TNF-induced apoptosis by stabilizing the E3 ligase TRAF2
  JOURNAL   Cell Death Dis 14 (7), 480 (2023)
   PUBMED   37516734
  REMARK    GeneRIF: The deubiquitinating enzyme OTUD7b protects dendritic
            cells from TNF-induced apoptosis by stabilizing the E3 ligase
            TRAF2.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8043)
  AUTHORS   Gong,Z., Li,A., Ding,J., Li,Q., Zhang,L., Li,Y., Meng,Z., Chen,F.,
            Huang,J., Zhou,D., Hu,R., Ye,J., Liu,W. and You,H.
  TITLE     OTUD7B Deubiquitinates LSD1 to Govern Its Binding Partner
            Specificity, Homeostasis, and Breast Cancer Metastasis
  JOURNAL   Adv Sci (Weinh) 8 (15), e2004504 (2021)
   PUBMED   34050636
  REMARK    GeneRIF: OTUD7B Deubiquitinates LSD1 to Govern Its Binding Partner
            Specificity, Homeostasis, and Breast Cancer Metastasis.
REFERENCE   6  (bases 1 to 8043)
  AUTHORS   McNally,R.S., Davis,B.K., Clements,C.M., Accavitti-Loper,M.A.,
            Mak,T.W. and Ting,J.P.
  TITLE     DJ-1 enhances cell survival through the binding of Cezanne, a
            negative regulator of NF-kappaB
  JOURNAL   J Biol Chem 286 (6), 4098-4106 (2011)
   PUBMED   21097510
  REMARK    GeneRIF: DJ-1 enhances cell survival through the binding of
            Cezanne, a negative regulator of NF-kappaB.
REFERENCE   7  (bases 1 to 8043)
  AUTHORS   Tran,H., Hamada,F., Schwarz-Romond,T. and Bienz,M.
  TITLE     Trabid, a new positive regulator of Wnt-induced transcription with
            preference for binding and cleaving K63-linked ubiquitin chains
  JOURNAL   Genes Dev 22 (4), 528-542 (2008)
   PUBMED   18281465
REFERENCE   8  (bases 1 to 8043)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   9  (bases 1 to 8043)
  AUTHORS   Evans,P.C., Smith,T.S., Lai,M.J., Williams,M.G., Burke,D.F.,
            Heyninck,K., Kreike,M.M., Beyaert,R., Blundell,T.L. and
            Kilshaw,P.J.
  TITLE     A novel type of deubiquitinating enzyme
  JOURNAL   J Biol Chem 278 (25), 23180-23186 (2003)
   PUBMED   12682062
REFERENCE   10 (bases 1 to 8043)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK044701.1, BB596613.2 and AC092094.19.
            
            On or before Jul 22, 2005 this sequence version replaced
            XM_619935.1, XM_110475.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC141397.1, SRR10223971.3947.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-147               AK044701.1         2-148
            148-293             BB596613.2         131-276
            294-2000            AK044701.1         353-2059
            2001-8043           AC092094.19        14237-20279         c
FEATURES             Location/Qualifiers
     source          1..8043
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 41.65 cM"
     gene            1..8043
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /note="OTU domain containing 7B"
                     /db_xref="GeneID:229603"
                     /db_xref="MGI:MGI:2654703"
     exon            1..293
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /inference="alignment:Splign:2.1.0"
     exon            294..444
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /inference="alignment:Splign:2.1.0"
     exon            445..633
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /inference="alignment:Splign:2.1.0"
     exon            634..861
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /inference="alignment:Splign:2.1.0"
     exon            862..963
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1091
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1204
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /inference="alignment:Splign:2.1.0"
     exon            1205..1332
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..1482
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1597
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /inference="alignment:Splign:2.1.0"
     exon            1598..1682
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /inference="alignment:Splign:2.1.0"
     exon            1683..8043
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5726..5731
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /note="hexamer: AATGAA"
     polyA_site      5748
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /note="major polyA site"
     regulatory      8017..8022
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /note="hexamer: AATAAA"
     polyA_site      8043
                     /gene="Otud7b"
                     /gene_synonym="2900060B22Rik; 4930463P07Rik; CEZANNE;
                     Trabid2; Za20d1"
                     /note="major polyA site"
ORIGIN      
        1 cggacggccg aaagccaccg atcctgaacc agccgctgga gtcggagtgg cgacccggtg
       61 tggaggagcc ggcggaaagc cattgggaag aggccagctc cggtcagtcc cggcttggct
      121 ccagctctat ctcctgtgga gagcaacagc cgcggtcgca gtgtccgcct ccgcctccat
      181 cgtcgtcggg ggaggggccg cttggacccc ggggtcactg ccgaggaatg aggcgaggcg
      241 gccgggcccc gcgctccgcc ccggcctaga gccttgcccc gagagtcgcg agggtcagag
      301 cctggatttg gatctatgtt ctgctcacat cctgctgcct gagagtacct gatgatccca
      361 tgaccctgga catggatgct gtcctgtcgg attttgttcg ttccacaggt gcagagccag
      421 ggctggctcg agatcttcta gaaggaaaga actgggatgt gagtgctgcc ctcagtgatt
      481 ttgaacagtt gcgtcaagtc catgctggga acctatcccc accctttagt ggagggagta
      541 cttgccctaa gacccctgaa aaagggggtt cggatagaga gcccactcgc ccttctcgac
      601 ccatccttca gagacaagat gacgtcattc aagaaaaacg cctgtctagg ggcatctccc
      661 acgccagctc cagcattgtt tccctggccc gctcccatgt ctcctccaat ggtgggggtg
      721 gggggagcag tgagcacccc ctggaaatgc ccatctgtgc cttccagctt ccagatctca
      781 ctgtgtacaa agaagacttc cgcagcttca tagagcgaga cctcattgag cagtccatgc
      841 tggttgcctt ggaacaggca gggcgtctga attggtgggt tagtatggac tccacctgcc
      901 agaggctgct ccctttagca actactgggg atgggaactg cctcctgcat gcagcatctc
      961 ttgggatgtg gggtttccat gatagagact tggtgctgag gaaagcgctg tatgcactga
     1021 tggagaaggg ggtggagaag gaagcactga gaaggcgctg gaggtggcag caaacacagc
     1081 agaataaaga gtcaggactg gtgtatacgg aagatgagtg gcagaaggaa tggaatgaat
     1141 tgatcaaact tgcttcaagt gaacccagaa tgcatctggg ttccaacgga gccagtggtg
     1201 gtggagtgga gagctccgag gagccggtat atgaaagcct agaggaattc catgtcttcg
     1261 tccttgctca tgtgctcaag aggcccatag tggtcgtggc agacaccatg ctgagggact
     1321 ctggagggga agcatttgcc cctatcccat ttggagggat ctatctgcca ttggaggttc
     1381 cagccagcca gtgtcaccga tcccctctgg tgctcgccta tgatcaggcc cacttctctg
     1441 cgcttgtgtc gatggagcag aaggagagcg ccaaagaaca agctgtgatc ccactcacag
     1501 attcagagca caagctgctg cccctgcact ttgctgtgga cccaggaaag ggctgggagt
     1561 ggggcaaaga tgacaatgac aatgtccgat tggccagtat aattctgtct ctggaggtga
     1621 agttacatct gctgcatagc tatatgaatg tgaagtggat cccactgtct tctgattcac
     1681 aagctcccct agctcagcct gagtccccca cagcctcagc tggagatgaa cccaggtcca
     1741 ctcctgagtc tggggagtca gacaaggagt cggttggcag cagttctctc ggcaacgagg
     1801 gcagcaggcg gaaggagaag tcaaagcgag accgggagaa ggacaagaag agagcagatt
     1861 ccgtggctaa caaactgggc agctttggca aaaccttggg cagcaagctt aagaagaaca
     1921 tggggggcct gatgcacagc aagggcccca agcctggagg gctggggagt gggtctggaa
     1981 taagcagtgg tacggagaca ttagaaaaga agaagaagaa caacacattg aagagctgga
     2041 agggtggcaa ggaagaggct gctggggatg ggcctgtgtc tgagaagccc ccgtctgagt
     2101 ctgttggcaa tggcgggagc aagtatagcc aggaggtgat gcaaagcctg agcactatga
     2161 ggatcgcaat gcaaggggag ggcaagtaca tttttgttgg aaccctgaag atgggccacc
     2221 ggcaccagta tcaggaggag atgatccagc gttaccttgc agatgctgag gaaagattcc
     2281 tggcagagca gaagcagaag gaggttgaga ggaagatcat gaatggaggg ttagttagtg
     2341 ggcctcctcc agccaaaaag ccagagccgg acggtgggga ggaccagccc agtgactccc
     2401 ccgcagagcc caaggcgatg gccttctcta ctgcttaccc tgggggcttt actatccctc
     2461 ggccttctgg gggtggagtc cactgccagg aaccccggag gcaattggca ggggggccat
     2521 gtgtaggggg cttaccatca tatgccacct ttcccagaca gtatcctggg cgaccgtacc
     2581 cccaccagga caacatccca gctctggagc caggcaaaga tggagttcac aggggtgcct
     2641 tgttaccacc ccagttccgt gtggctgatt cctatagcaa tggctacaga gagcccccag
     2701 agccagatgg atgggctgga gctccacggg gacttccccc aacccagacc aaatgcaaac
     2761 aaccgaactg cagcttctat ggacaccctg agacaaacaa cttgtgctct tgctgttaca
     2821 gggaagaact gaggcggagg gagcgggaac ctggtgggga actgctggca cacaggttct
     2881 gagtggctgg aaccttagtg gggacagggg ctaaacaaag aaagttaagc tcaactctgg
     2941 ctcatcagga cccagcccct gtgttgatgg ggcaagtgca gagaggggtg tgggggctgg
     3001 agtgctggca gtctggtggg agcagggctg ggctagctag cactacccca gggcagtact
     3061 gctcctgcgc acacagttga cttgagactt caaggcagaa gggggaagct cataacctct
     3121 tctgtcccaa tcccagggcc caagggaaag tagggaaata ctaggtgtgt gtgggtggga
     3181 ggtgggtgga caccttcggg gaggaacctg gaaagaaagt tctcaagtca gttaaggaaa
     3241 aaatagacca aagttcattg actttagaaa aaaagcacat ggtggtgtag ttgggagtat
     3301 tgagtcgatc tgagatactg aacaaatttg attttggttt gaattaggta gatattaggg
     3361 ttgaataaat tctccctgaa ggatcaaggc agtaatgtat gtgcttggcc tggttacaca
     3421 gaaagggtgg tttaaatccc agtgaatgga aataggaagg aggaacttaa aggggagtct
     3481 ttcctagaga gttttatgtt cttctagata ctcatctgcc atccattcta gttttagggg
     3541 agactgcctg ttgccctacc ttttcctcat cctttttaag gattgagctc agctaagtta
     3601 agatgtgatt ttttttttaa atattttttt ttaaagcaag ttccctttgg gaaagagaag
     3661 agtggtaaga agcaaccttg tatatggggt ttcttcaggt gaacgggtgc agagtgatct
     3721 attttttaac tacttagcaa taactacatg tgggtttgag tgcacctgag aaggggtgga
     3781 ggagcccaga tgtttggcta gactgtttga aacaatacca aaaacctcta tagagcacta
     3841 tcctctgctg ctgtgtttct gtagaaagca acctatttta ctaatttttt aaagaaagac
     3901 aggaccctga cagagaacat ttaaaagtta ctgactcctg cccctaccta agtgggtttc
     3961 tccttcctgt cacttctgga gagtgaactt aacaccctgg cttcttttgt taagccgtgg
     4021 ctgaccttaa tctgtggtta gtttattaaa ataataaaaa atactttgta agaaaaatta
     4081 tttttgatat tagggctggt gttgaagcat gggatggggg ctaggggcca ctttgaaagg
     4141 tagctagaga actctatttt agtgagctgt cgccatgggc cgcacggtcc cagtgatctg
     4201 acctgccttt ggatatctcc cttttcctga gccagccctg ttctccagag gggtagggct
     4261 ggacccagtg gtgagagctc ccttgcaatt tgcacaaagc acaagtctgg acagcttctg
     4321 ctctgaccag agctatttct aagagcttta aacctgaagg ctatcctgcg ccaattgtcc
     4381 cttctcctta ttttttttcc tggggaaaaa tcatctatgc aattctatac aaatgaattc
     4441 tgtgttcatt tgtggatgca aatgaagaag gggtgagtgc actgcacgtg tccagagtta
     4501 cctggggctg tttctgggct ccaatttctc tgctgaggta tgtcatcacc cactaatgga
     4561 atgttatccc cgaatttgat ttaagtcaca aatggctaga tgtgcatgtt tgtgcgtgtg
     4621 tgagatggga ctccagtgca tgtttcctct gcctagtcag aaaaatgatc aaacacctct
     4681 ctttggtaac aaagctagtc aagacttctt tatggaatta ttaagtttaa gaagttgtcc
     4741 cccaccccct caaaaagttt gaaagtcatt cacttccaag tctgccaatc tgttgatttc
     4801 ataatttccc atcattattt tttgactatt ttttgtttgt atctttgcta tgtagccctg
     4861 gctagccagt ctggtacttg ctatataacc caggttagcc tccaactcat agcaaccctc
     4921 ctgcctcagt cttctgagtg ctgataccta ggcatgaacc accacaccca gctttctaca
     4981 ggctgaaacc tagtatgaga taagcatttc tggcaggtgc ataatttaaa gatctactag
     5041 gaaattgagg gttatttttg ttttgttttt agataggatc ctatcctgta gcccaggctg
     5101 tccttgaatg tatatgatct tgcttcaaat ttgccaagtt ctgggatcac atcataccag
     5161 acatttttta aaatttcaat atataagcat taaaaaccca gattgaacaa aacatcaaaa
     5221 tcttaggatg tatcaggaat ggtattaagg tgaaagaggt aagagccctt aattgaacaa
     5281 atatgaggac aaatcctgtc tacttaaatt gtgatatgtt cataaagatg tttttacatt
     5341 taaaaatttt tattttcttt aaatactgta tcaagacagt acttatcttg attcgtgagt
     5401 tttaagcact ccttcagttt tctcccagtg agtggtaggt gaatgcctcg tgccttgcta
     5461 gcatcacctc agacttgtcc cagtttctga agcttgaata atgcaggtga aaccttcacc
     5521 gtgagcccct cttcctggct gcagtcaccc tgtgtgcact tctgtcatcc ttctcccaca
     5581 acatacatag gatgcctacc tgcctgggtg ggaatgcaaa cagcccagca ggggttttcc
     5641 tgtagaataa aaccagggaa ttccatttcc tttgggctgc tgtgtttgga cttggtctgt
     5701 tattagattg tataaactga ggacaaatga agagaatcag aaaacttgta tcatgttgtt
     5761 tttatttata tagtacccaa tcttagttct gcttgccttt ctgaagagaa aataaaaaag
     5821 ttccagggaa agggaagaga ggtctaaggt catatgggaa atgggtattg ggtcttttaa
     5881 ctttttgtta aattagtttt aatttggagg gtgactatta aggcatcaat tttaaagatg
     5941 agggactctg agacattatt atttttttaa tgagggcttg tgagattttc attctgtgtt
     6001 ttttagggtg gaggaggggt tgagtagggg tggagttaag gaacgtctgg gaaacaaaac
     6061 aaagatcaac ttgttcagaa taagcaagcc catgcagata ctgtggtggg gagaagggag
     6121 ggttgtgtgg ggagcatcca cgtgagtaaa ccttccttat ttacgagggt cctgtgtgtg
     6181 atgggggtgg gggtcctaga cgaggtaagt cctcatctct caggcttaca ttaagtgcaa
     6241 ttactcttta taatccaggg catctggggt cctactaaag ttttaacgga gagagatctt
     6301 cagggttctt attttcctcc tttccactct ctccaccctg catcctctgt accatcccca
     6361 acttaaagcc agtacaccag agggctgacc tccaaacccc ttaactcagg ctggcttaac
     6421 tgggcagtgg tggctcacac ctttaatccc agcacttgcc aggcggattt ctgagttcga
     6481 ggccagcctg gtctacagag tgagttccag gacagccagg gctacacaga gaaaccctgt
     6541 ctcgaaaaac caaaaaaaaa aaaaaaaaaa ggagaattga aaaagggttt cctcatactg
     6601 cagtttgtaa atgatataaa ttatatcttt ttatttagtt tttaagatgc aatttctaag
     6661 agtgagggat ggtgttaagc tccatgctgt gccttaaaat agaagtacct tccctctcca
     6721 tagctttcca aaatccatag accagtaaag cagaaatgac catggcttta tattgtacac
     6781 ttgggaggtg atcccgagcc gagaacagag cccgttctct gagatcttgc tcttgctgtt
     6841 cttcctttca ctcccatgtc caaggttcca ggcactttat ttttctttca ataaaggagc
     6901 atttgggtaa tgattgtcta tgagttactc agacacctct gactggactg tgtcctcttt
     6961 ttcaaagagg cagtacccag ccacatagcc ataggcaaga ggacagaatt agaagccatt
     7021 atctgctctg gaaacataca taccctggat tctaatattt tcttcttgcc ctcaacctgt
     7081 gtggactgca ggctcaatga gtcacacagg cactcgtgtc tgaatatctt gtggataccc
     7141 agtcacaagt tattgtgtat tgcctcctgt gcttaagctg tttaacaaaa tactatcatg
     7201 cttccatgta caattcctgt gccctctcct tcccttggct gtgtgagttg ggggtagagg
     7261 aagtgataga agctgtctaa gcagtggggt gggaaggacc ttggcctctt tctgtgttta
     7321 taactggatc tgtgattcat cctgtgagtc actcagctcc accttcctcc tccagctacc
     7381 cctcccagca gcccttgctc ctggcacaaa cctataacca gagcgagggt ctgaaaatgg
     7441 aaaaatctga cacagctcct tgcctctcta tcccctttcc atccagtgga catctatctg
     7501 catttgtgct gcaggtggtg agagtcttcc tgttaaccta atcctcaact gcagcccctt
     7561 tgtgcttctg gttaggcgat gatcacatca cttctctccg tcctgaccat tccctctata
     7621 ttctgctgtt cccatacctc aagatattaa agaacagaat gaggctttcg gaggaaagtg
     7681 gtggggagaa gaaaagtagg tcatgggatt ttggcacacc tgttcctaag ctgttcctta
     7741 ctacatactt tattccagaa gcattgaggt gtgtggtggg gtggtggtga ccagcagtct
     7801 ttaggacttc tacaatcagg cgtctagacc agcttgctag caagtacata cctgtttgtt
     7861 ccagtctctg ctcatgctag ttcactattt ccacagttgc agccaacaaa gagaactttg
     7921 gaagctgagg ctggaaggat gtgtgctgtg gggaagggag tgttgaatgt cacggccccc
     7981 acctaaggat tgctgcctct gtacagactc aaaaacaata aaacagcagc tcattaacac
     8041 cta
//
