LOCUS       NM_001177567            9009 bp    mRNA    linear   ROD 08-FEB-2025
DEFINITION  Mus musculus otogelin-like (Otogl), transcript variant 1, mRNA.
ACCESSION   NM_001177567 XM_001478590 XM_893664
VERSION     NM_001177567.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9009)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 9009)
  AUTHORS   Li,Z., Zhang,Y., Zhang,X., Cao,C., Luo,X., Gui,Y., Tang,Y. and
            Yuan,S.
  TITLE     OTOGL, a gelforming mucin protein, is nonessential for male germ
            cell development and spermatogenesis in mice
  JOURNAL   Reprod Biol Endocrinol 19 (1), 95 (2021)
   PUBMED   34174893
  REMARK    GeneRIF: OTOGL, a gelforming mucin protein, is nonessential for
            male germ cell development and spermatogenesis in mice.
            Erratum:[Reprod Biol Endocrinol. 2021 Sep 8;19(1):136. doi:
            10.1186/s12958-021-00803-3.. PMID: 34496867]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9009)
  AUTHORS   Avan,P., Le Gal,S., Michel,V., Dupont,T., Hardelin,J.P., Petit,C.
            and Verpy,E.
  TITLE     Otogelin, otogelin-like, and stereocilin form links connecting
            outer hair cell stereocilia to each other and the tectorial
            membrane
  JOURNAL   Proc Natl Acad Sci U S A 116 (51), 25948-25957 (2019)
   PUBMED   31776257
  REMARK    GeneRIF: Otogelin, otogelin-like, and stereocilin form links
            connecting outer hair cell stereocilia to each other and the
            tectorial membrane.
REFERENCE   4  (bases 1 to 9009)
  AUTHORS   Yariz,K.O., Duman,D., Zazo Seco,C., Dallman,J., Huang,M.,
            Peters,T.A., Sirmaci,A., Lu,N., Schraders,M., Skromne,I.,
            Oostrik,J., Diaz-Horta,O., Young,J.I., Tokgoz-Yilmaz,S.,
            Konukseven,O., Shahin,H., Hetterschijt,L., Kanaan,M., Oonk,A.M.,
            Edwards,Y.J., Li,H., Atalay,S., Blanton,S., Desmidt,A.A., Liu,X.Z.,
            Pennings,R.J., Lu,Z., Chen,Z.Y., Kremer,H. and Tekin,M.
  TITLE     Mutations in OTOGL, encoding the inner ear protein otogelin-like,
            cause moderate sensorineural hearing loss
  JOURNAL   Am J Hum Genet 91 (5), 872-882 (2012)
   PUBMED   23122586
REFERENCE   5  (bases 1 to 9009)
  AUTHORS   Shahin,H., Rahil,M., Abu Rayan,A., Avraham,K.B., King,M.C.,
            Kanaan,M. and Walsh,T.
  TITLE     Nonsense mutation of the stereociliar membrane protein gene PTPRQ
            in human hearing loss DFNB84
  JOURNAL   J Med Genet 47 (9), 643-645 (2010)
   PUBMED   20472657
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC113439.14 and AC123948.4.
            
            On Jun 20, 2019 this sequence version replaced NM_001177567.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            inferred exon combination        :: based on alignments, homology
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-303               AC113439.14        105746-106048       c
            304-343             AC113439.14        104589-104628       c
            344-392             AC113439.14        103535-103583       c
            393-459             AC113439.14        96718-96784         c
            460-558             AC113439.14        94914-95012         c
            559-713             AC113439.14        93129-93283         c
            714-835             AC113439.14        89364-89485         c
            836-1041            AC113439.14        85738-85943         c
            1042-1169           AC113439.14        80620-80747         c
            1170-1276           AC113439.14        80136-80242         c
            1277-1383           AC113439.14        75364-75470         c
            1384-1509           AC113439.14        75020-75145         c
            1510-1618           AC113439.14        73116-73224         c
            1619-1665           AC113439.14        72236-72282         c
            1666-1811           AC113439.14        71666-71811         c
            1812-1935           AC113439.14        70467-70590         c
            1936-2113           AC113439.14        68034-68211         c
            2114-2238           AC113439.14        63147-63271         c
            2239-2448           AC113439.14        60263-60472         c
            2449-2614           AC113439.14        55814-55979         c
            2615-2689           AC113439.14        54735-54809         c
            2690-2742           AC113439.14        52564-52616         c
            2743-2905           AC113439.14        50637-50799         c
            2906-3013           AC113439.14        47915-48022         c
            3014-3152           AC113439.14        46936-47074         c
            3153-3287           AC123948.4         190769-190903       c
            3288-3437           AC123948.4         184978-185127       c
            3438-3557           AC123948.4         183033-183152       c
            3558-3674           AC123948.4         180163-180279       c
            3675-3831           AC123948.4         177009-177165       c
            3832-3858           AC123948.4         175998-176024       c
            3859-4026           AC123948.4         171705-171872       c
            4027-4305           AC123948.4         169610-169888       c
            4306-4423           AC123948.4         166674-166791       c
            4424-4503           AC123948.4         161818-161897       c
            4504-4542           AC123948.4         161418-161456       c
            4543-4589           AC123948.4         157238-157284       c
            4590-4767           AC123948.4         153582-153759       c
            4768-4910           AC123948.4         152518-152660       c
            4911-4934           AC123948.4         152279-152302       c
            4935-5027           AC123948.4         152096-152188       c
            5028-5217           AC123948.4         149854-150043       c
            5218-5432           AC123948.4         146713-146927       c
            5433-5574           AC123948.4         145024-145165       c
            5575-5760           AC123948.4         144002-144187       c
            5761-5973           AC123948.4         142811-143023       c
            5974-6078           AC123948.4         142312-142416       c
            6079-6186           AC123948.4         141951-142058       c
            6187-6288           AC123948.4         140662-140763       c
            6289-6393           AC123948.4         140304-140408       c
            6394-6434           AC123948.4         140177-140217       c
            6435-6498           AC123948.4         135362-135425       c
            6499-6677           AC123948.4         134191-134369       c
            6678-6782           AC123948.4         133636-133740       c
            6783-6902           AC123948.4         131989-132108       c
            6903-6948           AC123948.4         130862-130907       c
            6949-7028           AC123948.4         126280-126359       c
            7029-9009           AC123948.4         123626-125606       c
FEATURES             Location/Qualifiers
     source          1..9009
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 56.11 cM"
     gene            1..9009
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /note="otogelin-like"
                     /db_xref="GeneID:628870"
                     /db_xref="MGI:MGI:3647600"
     exon            1..303
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     CDS             252..7229
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; otogelin-like protein"
                     /codon_start=1
                     /product="otogelin-like protein isoform 1 precursor"
                     /protein_id="NP_001171038.1"
                     /db_xref="CCDS:CCDS56747.1"
                     /db_xref="GeneID:628870"
                     /db_xref="MGI:MGI:3647600"
                     /translation="MVPWRALSLPILLVSLRGYVCASSVLSETSESEFYENEQRRALL
                     AVQFEATSPRYFFHEAINWGESKIKGSCPHECLNGAFCSKTGTCDCQIFQALGTRCQI
                     VPNMGSGRDGICKTWGQYHFETFDGIYYYFPGSCSYIFAKDCGNLEPQYTVWVHNSPK
                     CLGSVYSCYRSISLFFSNQEEIRIYGHEIRKNGISLSLPQTLGQVHLEKVADYILVKT
                     TFGFSLAWDGISGIYLKLSEEHRGKSCGLCANYNGIQSDDFVILQEDYTEDIAMFANS
                     WLVLTPDDTKCVPTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIA
                     SCVNDLCKTDDDETYCRAATEYARACSHAGFPIQDWRDDFPACTDKCDDSFVHRDCIS
                     CCPPSCTFEKQCLGSNLHCLDGCYCADGLIMDNGTCISLESCPCSFHGLAYSVGSKIE
                     QECTECVCVGGVWNCTEHDCPVQCSVVGDSHFTTFDGRHYSFIGLCQYILVKGTGKDR
                     FTITLQKAHCEQNLGLVCLQSITLILEDDFNKQVTLSRGGQIVTSPNQGFTLNGIVEI
                     QTLSSLFILLRTTFGLKILFAIDGERIYIQLSSAWKRRTLGLCGTFNGNIRDDFLSPS
                     GMIEGTPQLHAHAWRVSSTCFAPVHVPMVDPCNINQQNIGYAAHCDVIHQELFAPCHV
                     YVSPGLYYQLCRHDACKCGSPCLCNALAHYAYLCGQRGVPIDFRAHISFCAVVCQKGM
                     LYHHCSSLCLRSCTSLSSPEQCKDDCAEGCNCPEGKFYEETLNFCVPIYHCRCHYRGS
                     IYQPGELIPTPSGLCQCSNGTVKCDELATPSTVHACPEGKEYFDCRFPDPALPAGGIN
                     CETTCANLAMNFTCAPSSPCISGCVCAAGMAEHKGKCYVPESCPCIWKDWEYSSGEVI
                     STPCYTCVCRRGMFNCTYYPCPAVCTVYGDRHYHSFDGLEYDYISDCQVFLIKSTDDS
                     DISVISQNKKCFDNDIVCSKSVLISIGDTEIYLNDAPYKQKRSGFFLESRPEYQLWKA
                     GFYIVIYFPEEDITILWDEKTTIHIKVGPQWKNKLAGLCGNFDKCTSNDMTTSNNIEV
                     RNAQVFGDSWALGQCEDLMEALKPCEAHQNKFPYAKRECSILYSDVFAPCRNVIDVTS
                     FAKNCHEDTCNCNLGGDCECLCTSVAAYAYKCCQEGVPVHWRSPTVCALDCEYYNQGL
                     GEGPYMLASYGQSGLVLGANMTSRSVFSLPRSNNRGNLFFIFMITPGLFKEKTSSLAL
                     VSLESAERPNYFLYVHDNDTLSLKLWRANSEFHQRATFFHHQGLWIPGYSAFELYSKK
                     GYFIVFMGSSVKASKYDDSEEFKQSSSFSIEEIQAVVPYRRMCEWRYEPCATPCFKTC
                     SDPEALACTFLPPVEGCLPYCPKNMILDETTLKCVHPEDCIPLFPTEPALPPDITPSD
                     MTPTPGLECEPQQFDPVYNCSQYICLNMEWTFYNWSLNCPKDLEMPDCGFRGWPVQVN
                     TDICCPEWECPCRCSMLSELSIITFDGNSAALSSMASYILVRVPGEIVVVHIDKCSMN
                     QNGHALKKPASFGRISGLCFKKLNVTTSIHKILINRVVRKVDVDSIVVPLPFSSHELF
                     IEDSGTMYVITTPAGLIIKWAHLTGIIDIHFGPQFNLSSYTEGLCGICNDNPDDDLRM
                     QNGTIITNMEDIELFIGSWEIEKSFEVTMRRPVRNCTEYDCSHCIELLNREGFIPCHD
                     KVSPRDFCEKMWINYTYFWSYECDAISAYVALCNKFDICIQWRTPDYCPLSCPEGKEY
                     QPCVRPCEARTCLNKWFYGHSSCLNLREDCVCKNGTILHRPDKTLCIPEQECVCTDRE
                     EHPRSAGEIWNGGIDECTLYKCLEDGNIIPIEPVCEEEPSPICERTAEVVIGIVDKLT
                     CCSKKVCGCDMSLCDRTIPPCTNSQKLIVGYSALSCCPQYECECDTVRCPDISTPVCR
                     DDQFVLQVRQGEPCCFYPSCVCKTCTEPTPQCTDGEFLTVNINTTHLCCPQYYCVCEP
                     DLCPPPSLECAKDMNLVKENVSGQCCPNWRCECNCETLVMPTCDVGEFAAIDQNFQTD
                     CGCVQYLCEKDDVCVFQEVSVLNPGQSLIKYLEEEFCYIIECLDEKDNYTDFHTLNVT
                     MVNCSKDCDAHQIYIPSSSDYDCCGTCKNISCKFIMENGTSVIYEEGSTWHYNCSTYE
                     CVNTEEGATILNYSMVCPPFNETECKLNEGIVKLYNEGCCKICKREERICQKVIIKSI
                     IKKQDCVSQSSISVASCDGKCPSATIYNINVESHLRFCKCCRENGVRNVTVPLHCSGN
                     GTEVMYTLQEPIDCTCQWN"
     exon            304..343
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            344..392
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            393..459
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            460..558
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            559..713
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            714..835
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            836..1041
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1169
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            1170..1276
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..1383
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1509
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            1510..1618
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            1619..1665
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..1811
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            1812..1935
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            1936..2113
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            2114..2238
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            2239..2448
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            2449..2614
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            2615..2689
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            2690..2742
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            2743..2905
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            2906..3013
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            3014..3152
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            3153..3287
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            3288..3437
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            3438..3557
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            3558..3674
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            3675..3831
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            3832..3858
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            3859..4026
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            4027..4305
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            4306..4423
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            4424..4503
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            4504..4542
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            4543..4589
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            4590..4767
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            4768..4910
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            4911..4934
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            4935..5027
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            5028..5217
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            5218..5432
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            5433..5574
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            5575..5760
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            5761..5973
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            5974..6078
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            6079..6186
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            6187..6288
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            6289..6393
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            6394..6434
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            6435..6498
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            6499..6677
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            6678..6782
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            6783..6902
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            6903..6948
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            6949..7028
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     exon            7029..9009
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8989..8994
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /note="hexamer: AATAAA"
     polyA_site      9005
                     /gene="Otogl"
                     /gene_synonym="EG628870; Gm6924"
                     /note="major polyA site"
ORIGIN      
        1 gcattgctaa tgagagaccc agccaaaggg ctgactgtga gctctatcta aaacctcgga
       61 tgctgtgtgt ggttgagaag cccggggatt ttcttttcag tggttttatc ccataactgt
      121 gttcatttga atctgagcac acaaggaaca gtcacccttg taagatgcca tcatagtgaa
      181 gaccgtcact ttggtttcag tccagggaga aagagttcac tgaaatgagc attgtgaaga
      241 aactcagttt gatggtacct tggcgtgctc tctcccttcc tatactgctg gtttcattac
      301 gaggatacgt ttgtgcgtca tctgtcctgt cagaaacatc agaaagtgag ttctatgaaa
      361 atgaacagag aagggctctg ttagcagtac agtttgaagc aacctctccg agatattttt
      421 tccacgaagc tattaattgg ggtgagagta aaataaaagg ttcatgtcct catgaatgcc
      481 ttaacggggc tttctgttct aagacgggta cgtgtgactg tcaaatattc caggctctcg
      541 ggacaaggtg ccagattgtg ccaaacatgg gaagtggcag agatgggatt tgcaaaacct
      601 ggggacagta tcactttgaa acatttgatg gaatctacta ttatttccca ggaagttgtt
      661 cttatatatt tgcaaaggac tgtggtaatt tggagcctca gtacacagta tgggtccata
      721 atagcccaaa gtgccttggt tccgtgtatt cttgttaccg ctccatcagc ttattttttt
      781 caaaccaaga ggaaattaga atctatggac atgaaataag aaaaaatggg atcagtttat
      841 ctctgcctca gacacttggg caggtgcact tagagaaggt agctgactac attctggtga
      901 agacgacctt tggattttct ttggcttggg atggaatatc gggaatttac ctcaaactct
      961 cggaggagca cagagggaaa tcatgtggct tgtgtgcaaa ttataatggc atccagtcag
     1021 acgactttgt gatcctgcaa gaggactaca cagaagacat tgctatgttt gcaaatagct
     1081 ggctggtgct aactccagat gatactaaat gtgtacctac gccctcagac tttccaaatc
     1141 catgttccag tggaatgcca gcatttgagg caatcttctt caaatgccag atattgttac
     1201 agttcccctt tctgagctgc cacgaataca ttgatccata cttatacatt gccagctgtg
     1261 ttaatgacct gtgcaaaact gatgacgatg aaacttactg tcgagcagcc acagagtacg
     1321 ctagagcctg ttcccacgcc ggcttcccca ttcaagactg gagggatgac tttccagcat
     1381 gcactgataa atgtgacgat agcttcgtcc accgggactg tatcagttgt tgccctccga
     1441 gctgcacatt tgagaagcag tgtcttggga gcaatcttca ctgccttgat ggatgctatt
     1501 gtgcagacgg cctcataatg gacaatggaa cttgcatctc tttggagagc tgcccttgta
     1561 gttttcacgg attagcttat tcagttggtt caaaaatcga acaagagtgc actgaatgtg
     1621 tatgtgttgg tggagtttgg aactgcaccg aacatgactg tccagttcag tgttctgttg
     1681 tgggtgactc tcatttcacc acctttgatg ggcgtcatta ctcttttatt ggcttgtgtc
     1741 agtacatcct tgtgaaagga actggaaaag atagattcac gatcactttg cagaaggctc
     1801 actgtgaaca gaacctgggt ttggtctgcc ttcagtccat aactctaata ctggaggatg
     1861 actttaacaa acaagtgacg ctcagcagag gaggccagat tgtcaccagt cccaaccaag
     1921 gcttcaccct gaacggcatt gttgaaattc aaaccctgtc atccttattc attctcctaa
     1981 gaaccacctt tggtttaaag atcttgttcg ctattgatgg agaaagaatt tacattcagc
     2041 tttccagtgc ctggaaaaga aggacattag gtctgtgcgg cacctttaat ggcaacatta
     2101 gggatgattt tctttctcca tcaggcatga tcgaaggaac cccacagctc cacgcacatg
     2161 cgtggagagt ctcctccacg tgtttcgcgc ctgtccatgt cccgatggtg gatccctgca
     2221 atattaacca acagaacatt gggtatgcag cacactgtga tgtcatccac caggagctct
     2281 ttgctccttg ccatgtctac gtcagtcccg ggctgtacta ccagttgtgt cgccacgatg
     2341 cctgcaaatg tgggagcccc tgcctgtgta acgctctcgc ccactacgcc tacctgtgtg
     2401 gtcagcgtgg tgtgcccatt gatttcagag ctcacatctc cttctgtgct gtggtgtgtc
     2461 agaagggcat gctgtaccac cactgctcgt cactctgcct ccgctcctgc acctctctct
     2521 cctcccctga gcagtgcaaa gacgactgtg ctgaagggtg caactgtcct gaaggcaaat
     2581 tctatgaaga gacacttaac ttttgtgtgc ccatatatca ctgccggtgt cattataggg
     2641 ggagcattta ccagccaggg gagctcattc caaccccctc aggcttatgc cagtgttcaa
     2701 atgggactgt gaaatgtgat gagctagcaa caccctctac tgtccacgcc tgcccagaag
     2761 ggaaggaata ttttgactgc aggtttcctg accctgcgtt accagctggt ggtataaact
     2821 gcgagacgac gtgcgcaaac ctggccatga acttcacctg tgctccatcc tcgccttgca
     2881 tcagtggctg cgtttgtgct gcaggaatgg cagaacacaa aggaaaatgc tatgttcccg
     2941 aaagctgtcc ctgcatctgg aaggactggg agtacagctc aggggaggtc atctctacac
     3001 cgtgttacac ctgtgtttgt cggcggggga tgttcaattg cacatattat ccatgtcctg
     3061 cagtatgcac agtatatggg gaccggcatt atcactcctt tgatggattg gaatatgact
     3121 atatcagcga ttgccaagtg tttttgataa agagtacaga cgattctgat atatctgtga
     3181 tttcccaaaa caagaaatgc tttgacaatg atattgtttg ttctaaaagt gttttgatat
     3241 caattggaga cactgaaata tacctcaatg atgctcctta caaacagaag cgatcagggt
     3301 ttttcctgga aagcagacct gagtaccagc tctggaaggc tgggttctac atagtaatat
     3361 acttcccgga ggaagatatc accattctgt gggatgagaa gacaaccatc cacatcaaag
     3421 tcgggccaca gtggaagaac aagctggcag gattgtgtgg taactttgac aaatgtactt
     3481 ccaatgacat gacaacatct aataacattg aagtgcgaaa tgctcaggtg tttggagaca
     3541 gctgggcctt aggacagtgt gaagatctta tggaggccct gaagccctgc gaggcacacc
     3601 aaaacaaatt tccctatgcc aagagagaat gttccatttt gtacagtgat gtttttgctc
     3661 cttgtcgcaa tgtgattgac gtcacctctt ttgccaagaa ctgccatgaa gacacgtgta
     3721 actgtaacct gggtggggac tgtgaatgcc tatgtaccag tgtggccgca tacgcttaca
     3781 aatgctgcca ggaaggggtg cctgttcact ggaggtcacc cactgtctgt gcccttgact
     3841 gtgaatatta taatcaaggg cttggggaag gaccttatat gctggcaagt tatgggcaaa
     3901 gtggccttgt tcttggtgcc aatatgacca gtagaagcgt tttctctttg cccagaagca
     3961 acaatcgtgg taatttattt tttattttta tgatcactcc gggccttttc aaagagaaga
     4021 catcctcatt ggctcttgtt tccttggaat ctgctgaaag gcccaactac tttctctatg
     4081 tccacgacaa tgacactctt agcttgaagc tgtggcgggc aaactcagaa tttcatcaga
     4141 gagcaacatt tttccaccac caaggcctct ggattcctgg ctacagtgca ttcgaattat
     4201 acagcaagaa aggctacttc atcgttttta tgggttccag tgtcaaagcg tcaaaatacg
     4261 atgactcgga agaattcaag cagtcaagta gctttagcat agaagaaatc caggcagtgg
     4321 tcccttacag gaggatgtgc gagtggagat acgaaccttg tgctactccg tgttttaaaa
     4381 catgcagtga tccagaggcc ttagcctgta cattccttcc accggttgaa ggatgcttgc
     4441 catattgccc caagaatatg atcctggatg agacgactct taaatgtgtt cacccagaag
     4501 actgcatacc actgtttcca acagaaccag cattgccacc agacattacc ccatcagaca
     4561 tgacaccgac cccaggtttg gaatgcgagc ctcaacaatt tgatcctgtt tataactgta
     4621 gccaatatat ctgccttaac atggagtgga ccttctacaa ctggtctctg aattgcccga
     4681 aggacttgga aatgcccgac tgtgggttcc gaggctggcc tgttcaagtg aatactgata
     4741 tatgctgtcc ggagtgggaa tgcccctgtc ggtgctccat gttgtcagag ttgagcatca
     4801 ttacatttga tgggaacagt gcagcactat ctagtatggc ttcttacatc ttagtaagag
     4861 tccccgggga aattgtagtt gttcacattg acaaatgttc catgaatcag aatggacatg
     4921 cccttaaaaa accagcttct tttggacgaa tctcaggact ttgttttaag aagctaaatg
     4981 tgacaacatc tatacataaa atacttatca acagagtggt aagaaaggta gacgtggatt
     5041 ctattgttgt gcctttgccc ttttcaagtc atgagctgtt catagaagat tctggaacaa
     5101 tgtatgtgat tactactcct gctggcttaa tcataaagtg ggctcacctt acaggaatca
     5161 tagacattca cttcggcccc cagtttaact tgtcatctta cacagaaggg ctttgtggga
     5221 tttgcaatga caatccagat gatgacctca ggatgcagaa tggcaccatc attaccaaca
     5281 tggaagacat agagttattt attggcagct gggaaattga gaaatcattt gaagtgacaa
     5341 tgagaagacc tgtgaggaac tgtactgaat atgactgcag tcattgcatc gagttattga
     5401 acagagaagg tttcattcca tgccatgaca aagtctcacc aagggacttt tgtgaaaaaa
     5461 tgtggatcaa ctacacctac ttctggagct acgaatgtga tgcaatctct gcatatgtgg
     5521 ctttgtgcaa caaatttgat atctgcattc agtggcgcac ccctgactat tgccctctga
     5581 gttgtccaga gggaaaggaa tatcagccct gtgtgagacc atgtgaagca agaacatgtc
     5641 tcaacaaatg gttctatgga cactcctcat gtctgaattt gagagaagac tgtgtgtgca
     5701 agaatggaac cattcttcac cggccagata aaacactatg catcccagag caagaatgtg
     5761 tgtgcactga cagagaggag cacccccgca gtgctgggga gatttggaat ggtggcatag
     5821 atgaatgcac cctctacaaa tgtctggagg atggaaacat tattcctata gagcctgtct
     5881 gtgaagaaga gccttccccc atctgtgaac gaacagctga agtggtcata ggcattgttg
     5941 ataagctgac ctgctgttct aaaaaagtct gtggctgtga catgagtttg tgtgacagga
     6001 ccatcccacc atgcacaaat agccagaagt tgatcgttgg ctatagtgct ctttcttgtt
     6061 gcccacagta tgaatgtgaa tgtgatacgg tgagatgtcc tgatatttca acgccagttt
     6121 gcagagatga ccagtttgtg cttcaagttc gacagggaga gccttgctgt ttctaccctt
     6181 cctgcgtttg taagacatgc actgaaccaa ctccacaatg taccgatggg gaattcctca
     6241 ctgttaatat caatactaca catttatgct gtcctcagta ctactgcgtt tgtgagccag
     6301 atctttgccc tccaccatca cttgagtgtg caaaagatat gaacctggtg aaagaaaatg
     6361 tatctggaca atgttgccca aactggcgtt gcgaatgcaa ctgtgagact cttgtcatgc
     6421 caacctgtga cgtgggagaa tttgctgcaa tagatcaaaa ctttcagact gactgtggct
     6481 gtgtacagta tctctgtgaa aaggatgatg tgtgtgtgtt ccaagaagta tcagtattga
     6541 atcctgggca atctctaata aagtatttag aagaggaatt ttgttatata atcgaatgtc
     6601 tggatgaaaa agataactat accgactttc atactttgaa tgttacaatg gtgaactgtt
     6661 caaaagactg tgatgctcac cagatataca ttccatcctc cagtgattat gattgctgtg
     6721 gaacatgtaa aaatatatcc tgcaaattta ttatggaaaa tggaacatca gttatatatg
     6781 aggaggggag cacctggcac tataactgca gcacgtacga atgtgttaac actgaggagg
     6841 gagcaacgat tctaaactac agcatggttt gccctccttt taatgaaact gaatgcaaac
     6901 tgaatgaagg gattgtgaag ctttataatg aaggctgttg caagatctgc aaacgagaag
     6961 agcgaatatg ccagaaagtg atcattaaat ccatcataaa gaaacaggac tgtgtaagcc
     7021 aaagctctat tagtgtggca tcttgtgatg ggaaatgccc gtcagctacc atatataaca
     7081 tcaatgttga aagtcacctg aggttctgca agtgctgtcg tgaaaatgga gtgcgaaacg
     7141 tgacggtgcc tctgcactgc tcaggaaatg gcactgaagt aatgtacaca ctccaggagc
     7201 cgatagactg cacatgccag tggaactgag tgctagcatt cgaaggaggc tgcacgacag
     7261 taacatgtca ggcagcgtca tctttcatca ctgttattta ggcacatggc agacttgcac
     7321 cctataatgt gtctttacca ctcttatgat ttgaaaacct aacagtggac ttgaaatatg
     7381 tatagtttta atggaaaaaa ttagatttgt tgttttattt tagtgaatta aattattgta
     7441 agttgtttag cggaaatgct gtcacattta aagctgtagg gtaggacaaa ttaagtctta
     7501 gtgtaaagta gaagcttgtg ctgcagaatg ctttccattc agtcccttgt gccctggttt
     7561 tggttttggt tttgtttgtt ttgatttgca aagtcttccg atgctgtcca aactgaggaa
     7621 gactttaatt tttctttcct agtcttatca atgtgattag ttgtaattgg ctcatagata
     7681 atcatagtga gttgtgtttc ttagaaacag aacatagaat tgtaggatgt tggcttagtt
     7741 aacacctcaa aaaatattag gaatgctatt gcaaattccc ctaattatta ttatttttta
     7801 catgtgatgg taccataaca tttctgggac ttctacagca atgtagcaac aatgtggcga
     7861 gtttacgtta aggactagac tcctttctag atattttggg ttctggtttc atgatcgttt
     7921 attgtaaatg atatagcaag gtgattttta aaaagtcaca gaatcttcca ttactagaaa
     7981 gcactggata ggattaaaac gtttttaaga ccaatatccc tttagaatgc tcatgcatac
     8041 aataatagtt atttcaattt taagggaaag aaaaccatag tgtcgttcat tatttagagg
     8101 aagaccagga gctatatttt tataccatta aaattattaa ttatattgtt attatttaac
     8161 atttagttta gttaatgttt atcactgggg acggtttcta aatatatcag tacactatga
     8221 aacctgaggg caactttgcc attaaaactg ctgctttgtc agtgcaggga catacagtta
     8281 tctgaacgta ttcataacgt tagaatggaa tgccgctctc tgaaactaca gaaaatcatt
     8341 gacatttgca aataacttgc tctgagatct ttgcaaattt ccaaagtctt tctaccaggg
     8401 agtatagaat tatttgagtt tcttccgtag taaaacgaga gtgccttagt gtggttatga
     8461 tcatcaatga aggtcagtgt caataaaagc acattaaaac ttcatcgaca agccaatgct
     8521 tggattttaa taggctagtg ccgacttgag ctatgtgact tgttttcaaa cattaatgtt
     8581 tccatttaaa aattatgctt ctaagaaata ctgtagttat gaagtgtttg gatttccaag
     8641 gtctcttaat aatgtgtaaa agtattacct ggaatgtcct gatgtctact ctacatgaaa
     8701 atgatttaca ttgtctgttt taatactggc attttctcta gatataaaca tttttgcgtc
     8761 tgtgattatt agcatattga tggagttgga cattcttgtc taaatacatt aacattttac
     8821 ataaagacat catgtatctc aatcagaaat ttgtaatata tgttacctat cactttcctg
     8881 taaattctac tctctgtgga ctatctatta ttaaatatta actgatcttt aaatcaattt
     8941 gtggggagaa gagaaatatt cttctgctat tttataaaca acaaataaaa taaatacatg
     9001 ttgaagttc
//
