LOCUS       NM_145950               3425 bp    mRNA    linear   ROD 07-MAY-2024
DEFINITION  Mus musculus oxidative stress induced growth inhibitor family
            member 2 (Osgin2), transcript variant 1, mRNA.
ACCESSION   NM_145950
VERSION     NM_145950.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3425)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3425)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   3  (bases 1 to 3425)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL807737.12, AK148243.1, BM949030.1, AK048731.1 and CJ313585.1.
            
            On Sep 21, 2017 this sequence version replaced NM_145950.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK048731.1, AK169678.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                AL807737.12        70190-70226         c
            38-600              AK148243.1         2-564
            601-601             AL807737.12        61780-61780         c
            602-794             AK148243.1         566-758
            795-910             BM949030.1         562-677
            911-2658            AK048731.1         901-2648
            2659-2998           AL807737.12        53119-53458         c
            2999-3425           CJ313585.1         1-427
FEATURES             Location/Qualifiers
     source          1..3425
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 6.66 cM"
     gene            1..3425
                     /gene="Osgin2"
                     /gene_synonym="C230027H09Rik"
                     /note="oxidative stress induced growth inhibitor family
                     member 2"
                     /db_xref="GeneID:209212"
                     /db_xref="MGI:MGI:2384798"
     exon            1..202
                     /gene="Osgin2"
                     /gene_synonym="C230027H09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             159..1811
                     /gene="Osgin2"
                     /gene_synonym="C230027H09Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="oxidative stress-induced growth inhibitor 2
                     isoform 1"
                     /protein_id="NP_666062.3"
                     /db_xref="CCDS:CCDS17987.1"
                     /db_xref="GeneID:209212"
                     /db_xref="MGI:MGI:2384798"
                     /translation="MPVWCCRCSLAGHFRNYSDTETEGEIFNSFVQYFGDNLGPKVKG
                     MPLVEETSLLEDSSVTLPMVIIGNGPSGICLSYMLSGYRPYLSSEAIHPNTILHSKLE
                     EARHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYESPSILHWKLEQHHY
                     IPHLVLGKGPPGGAWHNMEGSMLTISFGNWMELPGLQFKDWISSKRRNLKGDRVMPEE
                     IARYYKHYVKVMGLQKNFRENTYITSVSRLYRDQGDNGSQDRDISTKHLQNQKSKFIK
                     RNWEIRGYQRIAGGSHVPFCLFAENVALATGTLDSPAHLEVEGEEFPFVFHSMPEFGA
                     AINKGKLCGRVDPVLIVGSGLTAADAVLCAYNNNIPVIHVFRRRVTDPSLIFKQLPKK
                     LYPEYHKVYHMMCSQSYSADSGPLSDYTSFPEHRVLSFKADMKCILQSVSGLKKIFKL
                     SAAVILIGSHPNLSFLKEQGCYLGRNSSQPITCKGNPVEVDAYTYECVKEANLFALGP
                     LVGDNFVRFLKGGALGVTRCLATRQKKKQHLFVQRGGGDGVA"
     exon            203..357
                     /gene="Osgin2"
                     /gene_synonym="C230027H09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            358..494
                     /gene="Osgin2"
                     /gene_synonym="C230027H09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            495..686
                     /gene="Osgin2"
                     /gene_synonym="C230027H09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            687..778
                     /gene="Osgin2"
                     /gene_synonym="C230027H09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            779..3425
                     /gene="Osgin2"
                     /gene_synonym="C230027H09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2531..2536
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Osgin2"
                     /gene_synonym="C230027H09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2555
                     /gene="Osgin2"
                     /gene_synonym="C230027H09Rik"
                     /note="major polyA site"
     regulatory      2636..2641
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Osgin2"
                     /gene_synonym="C230027H09Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2659
                     /gene="Osgin2"
                     /gene_synonym="C230027H09Rik"
ORIGIN      
        1 cggcgctcat cactcgctgc gccgccctgc cgccggcggg gaggagcgga agccgctggc
       61 cggggacaga ctcccgcgcc tgtgagccgc ggtgcaggca gagcgcgcgc cgggaccagc
      121 ccgcggtcgg ccctcccgga ggacggcagc cgctctccat gcctgtgtgg tgctgccgct
      181 gctccctggc cggtcatttc agaaactata gtgacactga aactgaagga gagattttta
      241 attcttttgt gcaatatttt ggtgacaatt tggggccaaa agttaaaggg atgccattag
      301 ttgaagaaac gtctttactt gaagattcat cagtgacttt gcctatggta ataattggaa
      361 atggaccttc aggaatatgc ctttcatata tgctgtcagg ctacagaccg tatttatcat
      421 cggaagcaat acatccaaat acaatcttac atagtaaact agaagaagca agacatctgt
      481 ccattgtgga tcaggactta gaatacctgt ctgagggtct tgaggggcga tcgtccaatc
      541 cagtggcagt cctttttgac acccttcttc acccagatgc tgacttcgga tatgagtctc
      601 catccattct gcactggaaa ttggaacaac atcattatat ccctcactta gttcttggta
      661 agggcccgcc tggtggggca tggcataata tggaaggttc tatgttgaca atcagctttg
      721 gaaattggat ggagcttcct ggacttcaat ttaaagactg gatatctagc aaacgaagga
      781 acttaaaggg ggaccgtgtc atgccggagg aaatagctcg ctactacaag cactacgtaa
      841 aggtcatggg ccttcagaag aattttcgag agaatactta cataacctct gtatcaagac
      901 tctatagaga ccaaggtgat aacggtagtc aagacagaga tatttccaca aagcatttac
      961 agaaccagaa gtcaaaattt atcaagagaa actgggaaat cagaggctat cagcgaatag
     1021 caggtggttc tcatgttccc ttttgcctct ttgctgagaa tgtagctctt gcaactggaa
     1081 ctttggattc tcctgcccat ctggaagttg aaggggaaga gtttccgttt gtgtttcatt
     1141 cgatgcctga gtttggagct gctataaaca aaggaaagct gtgtggcaga gtggacccag
     1201 tgctgattgt aggttccggc cttactgccg ctgatgcagt gctctgtgcc tataacaata
     1261 atatccctgt gatccacgtg tttcgcagac gagtaactga tccaagctta attttcaaac
     1321 agcttcccaa aaagctgtat cctgagtacc acaaagtcta ccatatgatg tgtagtcagt
     1381 cctactctgc agactcaggt cctctgtctg attataccag ctttcctgag caccgtgtgc
     1441 tttcctttaa ggcagacatg aaatgcattc ttcaaagtgt ctctggattg aagaaaatat
     1501 ttaagctgtc tgcagctgta atcttgatag gttctcatcc taacctatct tttctaaagg
     1561 aacaagggtg ttacctaggc cgtaactcaa gccagccaat aacatgcaag ggtaaccctg
     1621 tggaggttga tgcatacacc tatgaatgtg ttaaagaagc caatcttttt gctttgggcc
     1681 ctttggttgg agataatttc gttcgattct taaagggagg ggcattgggt gttactcgct
     1741 gtttggctac aagacagaag aaaaagcagc atttgtttgt tcaaagagga ggaggagatg
     1801 gggtagctta aagttcacaa ggaatttaaa tggacacttt actattaaag agttttttaa
     1861 cagtggtttg cagtgtattg gcttgaatta actgggagag cctccagctg tcactcttca
     1921 agttagcaaa gcttggtatc ccaagttgta ttcaagtgtg tcaaaggtgt cactctcaga
     1981 taaacccaaa cactgccaac ttggtataat ttatgctttc atttaactag aacattcttt
     2041 tctaacttgg catttataaa gccagttatt cagacagaaa tcatacttaa ttcatactgg
     2101 gtcaccttac tgctcgagat ggtccaaggg acaagagcat aagcttcctc tgtagctcat
     2161 taggcattta gacttaactc ctcttgcaca gatctccaag ggttatgcgt gtagtccctg
     2221 acgtttgaag tacactctct aaatgaaaat gggctataaa tatgtttgag taggatagga
     2281 ggaagcattt gcaactcagg ttttatttat tttgaaacta tcagttatat aaacctaatt
     2341 tattatcaaa tatgatggtc attaaaaata tttttacaag ttgagatttt gacagatagg
     2401 tacttgatat ctttaacttc tcataattta atatttcaat aatgctgaca tccaagaacc
     2461 cactaagata ctttttagag atttattctg tttagccatc ataacagcta atgaatctga
     2521 tttgtaattc aataaattgt ggatggaact acttaccctt gtgtgaacac tgagttaatt
     2581 tctattaatg aaacatgatt tggggcacgg ttactgtttg ggtattggca gaattattaa
     2641 aggttaatgt ggaaaatcag attgtgccct ttcccattct caaagtgatt attttgagat
     2701 ctgtaacagt gttcattcat aggaaatgat accatagccc acagtggtta ttagatttat
     2761 ctcctctaat agtctcaatt gcatttccat agaaactgtg aaatgtgtta ctgctaaaca
     2821 aagtcttcca gggttcttgg gaaattaaat ttttcaaagt ttttttccct tggtggtgcg
     2881 ggtggggtgg ggtggggtgt ataattttat ctggaatgcg ctcactgaac ttctgtttgc
     2941 agtaccttaa atggacaacc tgctgttgag tgttgtgtta gcttagatgc tgagtggtca
     3001 tggctcaccg ccagtgctgt ttagtctgct gatagctagc acacctcctg gttactcctg
     3061 acaaccatta accgttctat acctgtcaca tctacttcta gccctttata aaaatgtaac
     3121 tactctctga gtgactacac acccttttaa aatgacacgt gtctgaccat acttgagcag
     3181 tctcctcctt gcccgggctt gagctctggg ttggactgat gcttttcttt aatgtctctt
     3241 ataaattgaa aatagcagta tcattaatgt aatttctggg gtaaaataat gctggctggc
     3301 attcctttat atttaaggag attgttttat atttcattgc agttgttggg aaggggatga
     3361 acttaataca ttttaagaat aagatgccat agtccttaaa taaacctggt acacgaacca
     3421 ctctc
//
