LOCUS       NM_027950               1976 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus oxidative stress induced growth inhibitor 1 (Osgin1),
            transcript variant 1, mRNA.
ACCESSION   NM_027950 XM_895278
VERSION     NM_027950.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1976)
  AUTHORS   Sah,R.K., Ma,J., Bah,F.B., Xing,Z., Adlat,S., Oo,Z.M., Wang,Y.,
            Bahadar,N., Bohio,A.A., Nagi,F.H., Feng,X., Zhang,L. and Zheng,Y.
  TITLE     Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung
            Development and Prenatal Lethality
  JOURNAL   Int J Mol Sci 21 (21), 8223 (2020)
   PUBMED   33153107
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC166781.7.
            
            On Jun 15, 2018 this sequence version replaced NM_027950.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC022135.1, ERR2844020.1873630.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-147               AC166781.7         43740-43886         c
            148-255             AC166781.7         39531-39638         c
            256-392             AC166781.7         38464-38600         c
            393-584             AC166781.7         37926-38117         c
            585-676             AC166781.7         37750-37841         c
            677-1976            AC166781.7         34777-36076         c
FEATURES             Location/Qualifiers
     source          1..1976
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 67.71 cM"
     gene            1..1976
                     /gene="Osgin1"
                     /gene_synonym="1700012B18Rik; Okl38"
                     /note="oxidative stress induced growth inhibitor 1"
                     /db_xref="GeneID:71839"
                     /db_xref="MGI:MGI:1919089"
     exon            1..147
                     /gene="Osgin1"
                     /gene_synonym="1700012B18Rik; Okl38"
                     /inference="alignment:Splign:2.1.0"
     exon            148..255
                     /gene="Osgin1"
                     /gene_synonym="1700012B18Rik; Okl38"
                     /inference="alignment:Splign:2.1.0"
     CDS             189..1625
                     /gene="Osgin1"
                     /gene_synonym="1700012B18Rik; Okl38"
                     /note="pregnancy-induced growth inhibitor"
                     /codon_start=1
                     /product="oxidative stress-induced growth inhibitor 1"
                     /protein_id="NP_082226.1"
                     /db_xref="CCDS:CCDS22704.1"
                     /db_xref="GeneID:71839"
                     /db_xref="MGI:MGI:1919089"
                     /translation="MTSWRHDSLGASSSEPLPVVIIGNGPSGICLSYLLSGHIPYVKP
                     GAVHPHPLLQRKLAEAPGVSILDQDLEYLSEGLEGRSQSPVALLFDALLRPDTDFGGS
                     IDSVLSWKRQKDRAVPHLVLGRNLPGGAWHSIEGSMVTLSQGQWMSLPDLQVKDWMRK
                     KCRGLRNSRATAGDIAHYYRDYVIKKGLSHNFVSGAVVTAVEWAKSEHGSPEVQASSP
                     LFQVNGYLTTKDHGHQPFSLRARNVVLATGTFDSPAMLGIPGETLPFVHHDLSALEAA
                     LRAGTVNPTSDPVLIVGAGLSAADAVLFARHYNIQVIHAFRRSVHDPGLVFNQLPKML
                     YPEYHKVQQMMRDQSILSPSPYEGYRSLPEHQPLLFKEDHQAVFQDPQGGQQLFGVSM
                     VLVLIGSHPDLSYLPRAGADLVIDPDQPLSPKRNPIDVDPFTHESTHQEGLYALGPLA
                     GDNFVRFVQGGALAAASSLLKKETRKPP"
     exon            256..392
                     /gene="Osgin1"
                     /gene_synonym="1700012B18Rik; Okl38"
                     /inference="alignment:Splign:2.1.0"
     exon            393..584
                     /gene="Osgin1"
                     /gene_synonym="1700012B18Rik; Okl38"
                     /inference="alignment:Splign:2.1.0"
     exon            585..676
                     /gene="Osgin1"
                     /gene_synonym="1700012B18Rik; Okl38"
                     /inference="alignment:Splign:2.1.0"
     exon            677..1976
                     /gene="Osgin1"
                     /gene_synonym="1700012B18Rik; Okl38"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1955..1960
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Osgin1"
                     /gene_synonym="1700012B18Rik; Okl38"
                     /note="hexamer: AATAAA"
     polyA_site      1976
                     /gene="Osgin1"
                     /gene_synonym="1700012B18Rik; Okl38"
                     /note="major polyA site"
ORIGIN      
        1 acagcctctg ggatccccag ggctaatggg catcctgttc ttgcagcagg gcaccgtgac
       61 aaagtctctc accgtgtgac caagttcctc tgagtgtcca gacaacccag gctcaccagc
      121 tccctccagc tatctaccat ccatcaggtc agctgccagc cccaggctga acacccaccc
      181 accgagctat gacctcctgg aggcacgact cccttggggc cagcagctca gagcccctcc
      241 cagtagtcat catcggcaat ggcccctccg gtatctgcct gtcctacctg ctctctggac
      301 acatccccta cgtgaaacca ggagccgtcc acccacaccc cctgctgcag agaaagctgg
      361 ccgaggctcc aggggtctcc atcctggacc aggacctaga gtacctttcc gaaggcctcg
      421 aaggccgaag ccagagtcct gtggccctgc tctttgatgc cctcctgcgt cctgacacag
      481 actttggagg cagcatagac tctgtgctct cctggaagcg gcagaaggac cgcgctgttc
      541 cccaccttgt cctgggacgg aacctccccg ggggcgcctg gcattccatt gaaggctcca
      601 tggtgacctt gagccaaggc cagtggatga gtctcccaga cctgcaggtc aaagactgga
      661 tgcggaagaa atgcagaggt ctccgcaaca gcagagccac agccggtgac atcgcccact
      721 actaccggga ctacgtgatc aagaaaggcc taagtcacaa ctttgtgtct ggtgccgtgg
      781 tcactgccgt ggagtgggct aagtccgagc atggcagtcc cgaggtccag gcatccagtc
      841 ccctcttcca agtgaatggc tacttgacta ccaaggacca cggccaccag cccttctcac
      901 tgcgggcccg taatgtggtc ctggccacag gcacctttga cagcccagcc atgctaggca
      961 tcccaggaga gaccctgccc tttgtccacc acgacctgtc agccctggag gcagcccttc
     1021 gggcaggcac tgtgaaccca acctcagacc cggtgctgat tgtgggagca gggctatctg
     1081 cagccgatgc tgtcctcttt gcccgtcact acaacatcca ggtgatccat gctttccgcc
     1141 ggtccgtgca tgaccccggc ctggtattca accagctgcc caagatgcta taccctgagt
     1201 accacaaagt gcagcagatg atgcgcgatc agtccatctt gtctcctagc ccctatgagg
     1261 gctaccgcag cctccctgag caccagccac tgctcttcaa agaggaccac caagcagtgt
     1321 tccaggaccc acaggggggc cagcagctct ttggggtctc catggtgctg gtcctcattg
     1381 gctcccaccc cgacctctcc tacctcccca gggcaggtgc tgacttggtc atagacccag
     1441 atcagccact gagtcccaag aggaacccca ttgacgtgga ccccttcacc catgagagca
     1501 ctcaccagga gggcctgtat gccctggggc cgttggctgg ggacaacttt gtgagatttg
     1561 tccagggcgg ggccctggct gctgccagct ccctgctgaa gaaggagacc aggaagccac
     1621 cttaacatta gcctggcacc ctgacaccca ggccctgaag aggaagaggg cttatcacag
     1681 cccagcggga cgtgagccca tctaaagatt tcccatttgg gaaccagtct ccccagcaga
     1741 aggggaagac ttgagccatg tggatggact atctgcccca gaggcatggg gaacacaggc
     1801 tgccctaccc tcaggcgaga tgaggcccca ggtgggagca gtagccatag accagggggc
     1861 ccccttgaaa ctgtcagtgt gtgctggagt cacagggcca gctgagtgtc caacttggag
     1921 ggccccaggc ccaacttttc accatcagat ctgtaataaa accagctgtg cctcca
//
