LOCUS       NM_172701               5028 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus organic solute carrier partner 1 (Oscp1), transcript
            variant 1, mRNA.
ACCESSION   NM_172701
VERSION     NM_172701.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5028)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5028)
  AUTHORS   Chen,S., Zheng,P., Wang,W., Yi,M., Chen,P., Cai,J., Li,J., Peng,Q.,
            Ban,Y., Zhou,Y., Zeng,Z., Li,X., Xiong,W., Li,G. and Xiang,B.
  TITLE     Abberent expression of NOR1 protein in tumor associated macrophages
            contributes to the development of DEN-induced hepatocellular
            carcinoma
  JOURNAL   J Cell Physiol 233 (6), 5002-5013 (2018)
   PUBMED   29227538
  REMARK    GeneRIF: Abberant expression of NOR1 protein in tumor associated
            macrophages contributes to the development of DEN-induced
            hepatocellular carcinoma
REFERENCE   3  (bases 1 to 5028)
  AUTHORS   Gineste,C., De Winter,J.M., Kohl,C., Witt,C.C., Giannesini,B.,
            Brohm,K., Le Fur,Y., Gretz,N., Vilmen,C., Pecchi,E., Jubeau,M.,
            Cozzone,P.J., Stienen,G.J., Granzier,H., Labeit,S.,
            Ottenheijm,C.A., Bendahan,D. and Gondin,J.
  TITLE     In vivo and in vitro investigations of heterozygous nebulin
            knock-out mice disclose a mild skeletal muscle phenotype
  JOURNAL   Neuromuscul Disord 23 (4), 357-369 (2013)
   PUBMED   23375831
REFERENCE   4  (bases 1 to 5028)
  AUTHORS   Hiratsuka,K., Momose,A., Takagi,N., Sasaki,H., Yin,S.A., Fujita,M.,
            Ohtomo,T., Tanonaka,K., Toyoda,H., Suzuki,H., Kurosawa,T. and
            Yamada,J.
  TITLE     Neuronal expression, cytosolic localization, and developmental
            regulation of the organic solute carrier partner 1 in the mouse
            brain
  JOURNAL   Histochem Cell Biol 135 (3), 229-238 (2011)
   PUBMED   21331566
  REMARK    GeneRIF: The results indicate that OSCP1 may have a role in the
            brain indirectly mediating substrate uptake into the neurons in
            adult animals.
REFERENCE   5  (bases 1 to 5028)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5028)
  AUTHORS   Hiratsuka,K., Yin,S.A., Ohtomo,T., Fujita,M., Ohtsuki,K., Isaka,H.,
            Suga,T., Kurosawa,T. and Yamada,J.
  TITLE     Intratesticular localization of the organic solute carrier protein,
            OSCP1, in spermatogenic cells in mice
  JOURNAL   Mol Reprod Dev 75 (10), 1495-1504 (2008)
   PUBMED   18324622
  REMARK    GeneRIF: mouse testis OSCP1 may indirectly mediate substrate uptake
            into meiotic and spermiogenic germ cells, within the cytosol.
REFERENCE   7  (bases 1 to 5028)
  AUTHORS   Kobayashi,Y., Tsuchiya,A., Hayashi,T., Kohyama,N., Ohbayashi,M. and
            Yamamoto,T.
  TITLE     Isolation and characterization of polyspecific mouse organic solute
            carrier protein 1 (mOscp1)
  JOURNAL   Drug Metab Dispos 35 (7), 1239-1245 (2007)
   PUBMED   17446263
  REMARK    GeneRIF: Report molecular cloning/functional characterization of
            Oscp1 from mouse testes.
REFERENCE   8  (bases 1 to 5028)
  AUTHORS   Kobayashi,Y., Shibusawa,A., Saito,H., Ohshiro,N., Ohbayashi,M.,
            Kohyama,N. and Yamamoto,T.
  TITLE     Isolation and functional characterization of a novel organic solute
            carrier protein, hOSCP1
  JOURNAL   J Biol Chem 280 (37), 32332-32339 (2005)
   PUBMED   16006562
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL627101.25, AK077909.1 and AI853667.1.
            
            On Oct 5, 2017 this sequence version replaced NM_172701.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077467.1, AK077909.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                AL627101.25        90895-90973
            80-1683             AK077909.1         1-1604
            1684-4572           AL627101.25        121196-124084
            4573-5028           AI853667.1         1-456               c
FEATURES             Location/Qualifiers
     source          1..5028
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 59.82 cM"
     gene            1..5028
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /note="organic solute carrier partner 1"
                     /db_xref="GeneID:230751"
                     /db_xref="MGI:MGI:1916308"
     exon            1..228
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..1256
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein OSCP1; organic solute carrier protein 1; organic
                     solute carrier 1"
                     /codon_start=1
                     /product="protein OSCP1 isoform 1"
                     /protein_id="NP_766289.2"
                     /db_xref="CCDS:CCDS38879.1"
                     /db_xref="GeneID:230751"
                     /db_xref="MGI:MGI:1916308"
                     /translation="MSVRTLPLLFLNLGGEMLYVLDQRLRAQNIPGDKARKVLNDIIS
                     TMFNRKFMDELFKPQELYSKKALRTVYDRLAHASIMRLNQASMDKLYDLMTMAFKYQV
                     LLCPRPKDVLLVTFNHLDAIKGFVQDSPTVIHQVDETFRQLSEVYGKLSEGEFQLIRQ
                     TLLNFFQDLHIRVSTFLKDKVQNSNGRFVLPVSGPVPWGTEVPGVIRVFSVKGKEVKK
                     MKFRHGGDYVAAQKEGSFELYGDRVLKLGTNMYSASRPVETHMSATSKNAASRAQENI
                     VPNPLAKEELNFLARLMGGMEIKKPSGPEPGFRLNLFTTDEEEEHAALSRPEELSYEV
                     ISIQATQDQQRNEELARIMGEFEITEQLEQNTSKGDDLLAMMDRL"
     exon            229..383
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            384..551
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            552..632
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            633..736
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            737..865
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            866..935
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1075
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1076..1139
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1140..5013
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1461..1466
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /note="hexamer: AATATA"
     polyA_site      1479
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /note="major polyA site"
     regulatory      2131..2136
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2153
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
     regulatory      4994..4999
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      5013
                     /gene="Oscp1"
                     /gene_synonym="1810007P19Rik; 5730415O04; 6030436A01Rik"
ORIGIN      
        1 ctttctgttc ccggcgttgc cccagcaacc gggctatgga cgcgtagggg cctccaggct
       61 gctaaatcac aaaccctggg gttcttcctt catctaccct gcgggtttcc ggcactatgt
      121 cggttcggac tctgccgctg ctctttttga acttgggcgg ggagatgctt tacgtcctag
      181 accagcgact gagggcccag aacatccccg gagacaaggc ccgcaaagtt ctgaacgaca
      241 tcatttcaac catgttcaac aggaagttca tggacgaact gttcaaaccc caggagctgt
      301 actccaagaa ggccttgcgg actgtgtatg accgcctggc tcatgcctcc atcatgcgac
      361 tgaaccaggc cagcatggat aagctctacg acctgatgac catggctttc aaatatcaag
      421 tgctgctgtg tccacgcccc aaggacgtgt tgctggtcac tttcaaccac ttagacgcca
      481 tcaagggttt tgtccaagac tctcccaccg tcatacatca ggtggacgag accttccggc
      541 agctgtcaga agtgtatggg aagctctctg aaggggagtt ccagctgatc cggcagacac
      601 tgctcaactt cttccaagac ctgcatatcc gagtgtccac atttctaaag gacaaagttc
      661 agaactctaa tggtcgcttt gtgttgccag tgtcggggcc tgttccctgg ggaactgaag
      721 ttcctggagt cattagagtg ttcagtgtca aaggcaaaga ggtgaagaag atgaaattcc
      781 ggcatggcgg agactatgtt gctgcccaga aggaaggttc ttttgagctt tatggagacc
      841 gagtcttgaa actgggaact aacatgtaca gtgcgagtcg tcctgtggaa acccacatgt
      901 ctgcaacatc caagaacgca gcctccaggg cacaggaaaa cattgttcca aaccctcttg
      961 ccaaagaaga gctgaatttc ttggccaggc taatgggagg gatggagatc aagaagccga
     1021 gtggccctga accaggattc cgactgaatc tgtttacgac cgatgaggaa gaggaacacg
     1081 cagcactgtc caggccggag gagttgtcct atgaagtcat cagcatacag gctacacagg
     1141 accagcaacg gaatgaggag ttggcccgga tcatgggtga gtttgagatc acagagcagc
     1201 tggagcagaa caccagtaag ggagacgact tgctggccat gatggacagg ttatagatgc
     1261 agatgggcac gccctagccc tccctcaaga gactgcctta gaccaccctg gacacggatg
     1321 gctggggatc tcatgtgccc ctgctggatt ccaaccaagg cctgcacctt ctagtccatt
     1381 tttaagtcag aaaaaaactg tgacgacctc tcggagagca tccatttctg aagccacaca
     1441 catttctgta ttttcagcaa aatatattct tgctcttaac ccagaccttc cccattattc
     1501 tcaactcaat gatgactatg ggcgcctcct gggccattgc gggttttcca cagcgtcttt
     1561 cctgcaggga ccagcgtcct atgcgtgcct gtaaggacaa aagagcaaca cctgaaaaca
     1621 caggaggggg atccaggcca ttctggctgc ataacaagat agatctttta aaaaaccaaa
     1681 accaaaacaa aacaaaaaaa agtttgggga ctcggggagt aaatgcacta gccatgtaca
     1741 cttggtgaca gaaattcgat tcctagaacc tacatgtcaa aaacctgctt tggggactaa
     1801 agaaatggct cagtggttaa gagcactggc tgttctatca gaggacctgg gttcaattcc
     1861 tggcacccac atggtggctc acaaccatct ttaatgggtt cttttattgt tgtcattgtt
     1921 ttgtttgttt tgtttttcaa gacagggttt ctctgtgtaa ctcaggctag cctcaaactc
     1981 agagatccac ctgcttctgc ctcccaaagg gctaggatta aggcgtgcgc cgccaccgcc
     2041 tggctgtaac gggttctgat gctctccccc ggcattcagg catacattca gacagtggat
     2101 tcatacataa aatgcataga tacatacatg aataaagtgt tgtggcaaag tgatgagcac
     2161 acatccgtaa tcttagcact tctactgaaa ggaaaactgt ctggaacctt gcaggccagc
     2221 tcacctgagg attgcagtat agccacagaa accagagcct caggaaccaa ctcaagtttg
     2281 agatcagcct aagctatagg agaccctctc tctcaaaaga acaaagaaag aaaggaagga
     2341 aggaaggaag gaaggaagga aggaaggaaa gaaagaaaga aagaaagaaa gaaagaaaga
     2401 aagaaagaaa gaaagaaaac aaataaacaa acctggggct atggctcagt gaacaatgtc
     2461 cagcagagga atgaagaccc aagttcaggt cccagaacat acaagaagcc agatgctatg
     2521 gcacatgttt gtaacctcag gatcctacag ggagatttga aacagagata agagaatccc
     2581 tagaagctcc caggccagct agccaggcat cgttcacacc agcaaaccag tgatcctgtc
     2641 tcctgtctca agaacacctt ccacatatgt gctatggcac acacgtatcc acacttacta
     2701 cacacacaca cacacgagag agagagagag agagagagag agattcaaag attaaattta
     2761 atctaagaaa attagtaaaa attctgagga gagttctgtt cagcttgctt tacaggtaag
     2821 tttgaaatca gagtaaaggg cagtcacttc agtgtgtaac tagtgtcaac ttgatgctag
     2881 cttgagtcac ttagagacca gagcctcagt tgagaaagtg cctccttaaa atcaggctgt
     2941 aggcaagcct gtagggcatt ttcttaatta gtgattgatg gggagggccc agcccattgt
     3001 gggtggggcc atccctgggc tggtggtctt gggttttata agagcaggac aggaagcagc
     3061 accccaccac agcctctgca tcagcttctg cctccaggtt ctctggctct gtttgagttc
     3121 ctgtcttttg atgatgaaca gtgacaataa gccaaacgaa ccgtttcctc cccaacttgt
     3181 ttcagtcatg gtgtttcctc acagtagaaa ccctaagaca gtttgtcatg gctcagttta
     3241 gaaggcctcc aaccctctcc cctaacacat tgggcgtcgt cacctccgag aggcagggta
     3301 acccaggcaa ggacaagaca ggcttgagag gcccagggag agcacctggg ggtcagatgt
     3361 ttgttcttcc aagcatgttc tcctccgagt ctacctttat caccaaaggc atccgtttgc
     3421 tgttacatct gtatcctgta ccatcaaaca ccaggcaggg ccttaggctg ggtgcctagg
     3481 aggtgtatgt gatgtgcctc ccccagggac tcacatgaac tgcctcaggt cagggctgcc
     3541 tgagatagtt cagaaaaggc caggaggcct gtcctacatg ctccctcctg ggaccagtaa
     3601 ccttgtgtac cctcagggcc agccaactgt cagaggtcag agtccattcc tatgagagaa
     3661 atatctgaat ggcacaggtg gcagagaacc acaactgatt aaggccactg tgtgaaacgg
     3721 ggtcagcttg aaggaccact gaggtcacac cccataggaa gtgtgaagat atggttttgg
     3781 aattcgagat cagggaacct gccctttggc ctttgacaca aggcatagtt tcaatcctga
     3841 aaggtaagtc atcagataaa ttcgctatct ctcacccatc gaagaaatcc cttaaccacc
     3901 aggtatgtcc aaccttttga aattgccaca aagttcaaca actgcacaat tgagggtttg
     3961 tttgtttttt ggtttttttt ttttttaatc atgatttagc tgggcagagg gccatacacc
     4021 tttaatccca gtactcagga tgcagaggcc atgaggcctg aggcctgagg atctctgagt
     4081 tcgaggccaa cctggtctac agagtgagtt ctaggatagc cagggccaca cagagaaacc
     4141 ctgtcttgaa aataaataaa taaataaatc caacaacatc ctccccccaa ccaaaacaac
     4201 aaaaaatatg ctcttgtttg ttttgaggca attcattaag acaggaaatg gggcatacac
     4261 tggctgggcc tctggaagag caatcagtgc tcttaaccac tgagccatct ctctagccct
     4321 ttgcttttgt ttttgtgttt gtttgtttgt ttgggttttt ttgtttgttt gtttttttga
     4381 gacagggtct cactatgtag ctctgactgt cctggtactt actatgtgac catgctggcc
     4441 tggaactcac agtgatccgc ctgcttctgc ctctcaagta ctaggaataa aggtgtgtgc
     4501 taccgagagc agctaaattt acaactctgt gttgggctgc atttatggct attctgagtc
     4561 acaagtatcc cctgggctgc aggctagacc cacctgtttc tgctggaaaa gaaacttcaa
     4621 ctgccttaaa ttgcctgcta caaatatacc acgtgaactc tgtttagcct ccaagctatc
     4681 tggcccacag ctggggactg actggggaaa gggaggggaa ggttctgtga tgctccatac
     4741 tgtcacagac gtagacttca ctgtcatctg ggactggatc taggagatgg gccacccttg
     4801 cccagaaacc acggcctcct ccctccactc gccctgcaga gatgcgaact atctgaaaca
     4861 tacctgtcct cctctgtaaa taaacaagag atacacatct gtgctgatga agcaatctct
     4921 gagtttcatg cttctaggcc tgcacaaata ttgagaaaaa caagtttatt tgcatgggag
     4981 tcagaaaggg aataataaaa aagaaaatag caaaaaaaaa aaaaaaaa
//
