LOCUS       NM_001310509            3594 bp    mRNA    linear   ROD 03-SEP-2024
DEFINITION  Mus musculus oxysterol binding protein-like 7 (Osbpl7), mRNA.
ACCESSION   NM_001310509 XM_011249265
VERSION     NM_001310509.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3594)
  AUTHORS   Duara,J., Torres,M., Gurumani,M., Molina David,J., Njeim,R.,
            Kim,J.J., Mitrofanova,A., Ge,M., Sloan,A., Muller-Deile,J.,
            Schiffer,M., Merscher,S. and Fornoni,A.
  TITLE     Oxysterol-binding protein-like 7 deficiency leads to ER
            stress-mediated apoptosis in podocytes and proteinuria
  JOURNAL   Am J Physiol Renal Physiol 327 (3), F340-F350 (2024)
   PUBMED   38961844
  REMARK    GeneRIF: Oxysterol-binding protein-like 7 deficiency leads to ER
            stress-mediated apoptosis in podocytes and proteinuria.
REFERENCE   2  (bases 1 to 3594)
  AUTHORS   Anniss,A.M., Apostolopoulos,J., Dworkin,S., Purton,L.E. and
            Sparrow,R.L.
  TITLE     An oxysterol-binding protein family identified in the mouse
  JOURNAL   DNA Cell Biol 21 (8), 571-580 (2002)
   PUBMED   12215260
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL606664.17, AK171585.1, AK017095.1, BY593908.1 and BE990127.1.
            
            On Mar 28, 2018 this sequence version replaced NM_001310509.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154677.1, SRR9219382.145342.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                AL606664.17        51882-51896
            16-2301             AK171585.1         1-2286
            2302-3091           AK017095.1         279-1068
            3092-3571           BY593908.1         12-491
            3572-3594           BE990127.1         1-23                c
FEATURES             Location/Qualifiers
     source          1..3594
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 60.75 cM"
     gene            1..3594
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /note="oxysterol binding protein-like 7"
                     /db_xref="GeneID:71240"
                     /db_xref="MGI:MGI:1918490"
     exon            1..134
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            135..286
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            287..412
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            413..466
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            467..580
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            581..676
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            677..794
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            795..898
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            899..991
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1124
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1125..1219
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1315
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..1453
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..1547
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1548..1795
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1796..1933
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1934..1997
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1998..2076
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2077..2221
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2222..2366
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2367..2493
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2494..2616
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2617..3579
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3557..3562
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3579
                     /gene="Osbpl7"
                     /gene_synonym="4933437E18Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtctccttcc ttcctggttc ctgcagtagc tgctgcaact gctcagttct gtgaagagct
       61 agccggtgac tcggagacag tctcaggcac agcagcgtac ggatcaagag gctctggcgt
      121 ccatggatcc tgggggttcc cccaggacaa ggtgacattc tccccaaccc acccggccct
      181 gccgtcctca tcggggagca acttcttcct catggacttc caggaaagag acacgccctc
      241 tttggctgag agtactcagt cttcaaagcc cagcagtacc cagcaggcct cggagctgtg
      301 ggaggtgatg gaggagcctc ggggcaggct gggagcagac gacatcatgc ctgagagaca
      361 ggaaggacac ctgctcaaga agaggaagtg gcctcttaag ggctggcaca agaggtactt
      421 tgtgctggag gacgggatcc tacactatgc cacgactcga caagatatca ccaaggggaa
      481 ggtccacggc tccatcgatg tccggctatc cgtcatgtcc atcaacaaaa aggcccagcg
      541 cattgacctc gacacagaag acaacattta ccacctaaag atcaaatctc aggacctgtt
      601 ccatagctgg gtggcccagc ttcgagccca ccgcttggcc cagcgcttgg acatgcccag
      661 tgccactcat cggaaggctc ctggtaccca gatgctaaca gcaggcagtg cttccgcctt
      721 acctggggtt ggacctcgag agaaagtgtc atcctggctg agggacagtg acgggctaga
      781 ccgatgttct catgcactct cagaatgcca gggtaagctg caggaactac acagactcct
      841 tcagagcctg gagtccctac accgcatccc ctctgccccc gtgatcccta cacaccagac
      901 ctcagtgacg accgagagac ccaagaaagg aaaacgaacc agtcgcatgt ggtgcacaca
      961 gggcttcgcc aaggatgaca ccatcggacg ggttggccgt ctccatggct ctgttcccaa
     1021 cctatctcgt tacttggagt ctcgggacac ttctggcccc cgtggcctgc cacctccaga
     1081 ctatgcccat ctgcagcgca gtttctgggc tctggcccag aaggtgcaca actccctcag
     1141 cagtgtcctg gttgccctca ccacagaacg ggaccgactg agagacctgc accagggctc
     1201 agagctgtca aggatggtag tttctgaggc cccggatggt cagagacgcc tccactcact
     1261 ctccatctcc tcagacacca cggcagactc cttcagttcc ctgaacccgg aggagcaaga
     1321 agctctgtac atgaaaggcc gagagctgac cccccagctg tcgcagagca gtgtgctgtc
     1381 cctcgccgac tcccacaccg agttctttga tgcctgtgag gtgctcctct ctgccagttc
     1441 ttccgagaat gagggttctg aggaggaaga gtcttgtgct agcgagatca ccaccagcct
     1501 gtctgaggag gtgctggata tcaggggagc tgaccgctat caaaaagggc cgtgtgttcc
     1561 agggattgct gtgggacctc ctcgccgccg ctgcctgcca gctgccagtg ggcctgggac
     1621 agacgtgagc ctgtggaata tcctccgcaa caacatcggc aaagacctgt ccaaggtgtc
     1681 gatgcctgtg cagctcaacg aaccgctcaa cacactgcag aggctctgcg aggagttgga
     1741 atatagcagc ctcctggacc aggccagccg catggccgac ccctgcgagc gcatggtgta
     1801 catcgcagcc tttgctgtct ctgcctactc ctccacgtac caccgggcgg gatgcaagcc
     1861 cttcaacccg gtcctgggag agacctacga gtgtgagcgg cctgaccggg gtttccgttt
     1921 tatcagcgag caggtctccc accatcctcc gatctccgcg tgtcacgcag aatctgagaa
     1981 cttcatcttc tggcaagaca tgaaatggaa gaacaagttc tggggcaaat ccctggagat
     2041 cgtgcctgtg gggacagtca atgtcagtct gcccaggttt ggggaccact ttgagtggaa
     2101 caaggtgacg tcctgtattc acaacatcct gagtggccag cgctggatcg agcactatgg
     2161 ggaagtgctt atccgaaaca cacaagatag ctcctgccac tgcaaaatca ccttttgcaa
     2221 ggccaagtac tggagttcca acatccatga ggtacaaggt gcggtgctta gtaggagtgg
     2281 ccgcgtcctc caccgcctct tcgggaagtg gcatgagggg ctgtaccgag gccccccacc
     2341 gggtgggcag tgcatttgga aacccaattc gatgcctcca gaccatgagc gaaacttcgg
     2401 gttcactcag tttgccctgg aactgaatga gctgacgtca gagctgaagc ggaccctgcc
     2461 ttccactgac acacggctcc gacctgacca gaggtacctg gaggagggga acatacaggc
     2521 tgctgaggcc cagaagagaa ggatagagca gctccagcga gaccggagaa gggtgatgga
     2581 agaaaataac atagtccacc aggcgcgctt cttcaggcga cagacagaca gcagcggcaa
     2641 ggagtggtgg gtgaccaacc atacttactg gaggcttcga gctgagccag gctatgggaa
     2701 cctggatggg gccgtgctct ggtaaccctg gccttggggc aggagactca aggtcctcgc
     2761 tcctgctcca actcctgtta tggacacatg ggtgaggtca ggctccctcg ccgtgccctt
     2821 gagtgcaaag gggcagccta ggctctagcc ctttcctcct ctgctggcca gaggggctat
     2881 atctcagcac actcccgtcc caacgctggg gtgaaagtgg actcggaacg ggaatccgtg
     2941 ctttccccgt cttgtgaccc caaatctggc atgtcagacc cttctcgctc agccatcttc
     3001 ctcatctggg agtgtttggg agagatgcca ggttccccag acctgctccc catttcagtg
     3061 ccttccttgg acacagaggg ccccttgatg ctccccagac ttcccgtgcc cggggcgctg
     3121 gctgtgctgt aaggttggag tgagtgaagg agaggagatg cccccttccc gtctgtttgt
     3181 cctctcttcc agcatcttcc ctgtgccctg acccatcccc ttgtcctgca tccccttctc
     3241 ccaaacggca aagcacccgc agcttcagct cctccgttcc ctgctccacc agtggtccct
     3301 tcaggctcag cttagcagaa gtcccaagag atggggagca gtctggggtg cctggcctca
     3361 gattcaccca ggagggagtg agccagtatg agtgtaagtt tgtgtaggag tgtgagtgtg
     3421 tgtgtcctgc ttgccggcga gcgggattcc taatgtagcc aggacacctc cgctgctgct
     3481 ggtgtctgtc actctgttgc tgctcatttt ctcagtttgc ctgagtcagg tgaattgctc
     3541 ttacattcca agctccaata aagactgtcc tagactttga aaaaaaaaaa aaaa
//
