LOCUS       NM_001290733            8301 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus oxysterol binding protein-like 6 (Osbpl6), transcript
            variant 2, mRNA.
ACCESSION   NM_001290733 XM_006500461
VERSION     NM_001290733.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8301)
  AUTHORS   Ye,Q., Bhojwani,A. and Hu,J.K.
  TITLE     Understanding the development of oral epithelial organs through
            single cell transcriptomic analysis
  JOURNAL   Development 149 (16) (2022)
   PUBMED   35831953
REFERENCE   2  (bases 1 to 8301)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8301)
  AUTHORS   Mochizuki,S., Miki,H., Zhou,R., Kido,Y., Nishimura,W., Kikuchi,M.
            and Noda,Y.
  TITLE     Oxysterol-binding protein-related protein (ORP) 6 localizes to the
            ER and ER-plasma membrane contact sites and is involved in the
            turnover of PI4P in cerebellar granule neurons
  JOURNAL   Exp Cell Res 370 (2), 601-612 (2018)
   PUBMED   30028970
REFERENCE   4  (bases 1 to 8301)
  AUTHORS   Ouimet,M., Hennessy,E.J., van Solingen,C., Koelwyn,G.J.,
            Hussein,M.A., Ramkhelawon,B., Rayner,K.J., Temel,R.E., Perisic,L.,
            Hedin,U., Maegdefessel,L., Garabedian,M.J., Holdt,L.M., Teupser,D.
            and Moore,K.J.
  TITLE     miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates
            Cholesterol Trafficking and Efflux
  JOURNAL   Arterioscler Thromb Vasc Biol 36 (5), 942-951 (2016)
   PUBMED   26941018
  REMARK    GeneRIF: Oxysterol-binding protein-like 6 is a novel regulator of
            cholesterol trafficking that is part of the miR-33 and miR-27b
            target gene networks contributing to the maintenance of cholesterol
            homeostasis.
REFERENCE   5  (bases 1 to 8301)
  AUTHORS   Anniss,A.M., Apostolopoulos,J., Dworkin,S., Purton,L.E. and
            Sparrow,R.L.
  TITLE     An oxysterol-binding protein family identified in the mouse
  JOURNAL   DNA Cell Biol 21 (8), 571-580 (2002)
   PUBMED   12215260
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY704583.1, CJ104457.1, AK044411.1, AL928867.9 and AI597353.1.
            
            On Mar 19, 2014 this sequence version replaced XM_006500461.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR, and
            lacks an alternate in-frame exon in the central coding region,
            compared to variant 1. The encoded isoform (b) is shorter than
            isoform a.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK044411.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                BY704583.1         1-20
            21-30               CJ104457.1         18-27
            31-4211             AK044411.1         2-4182
            4212-7842           AL928867.9         17993-21623
            7843-8301           AI597353.1         1-459
FEATURES             Location/Qualifiers
     source          1..8301
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 44.94 cM"
     gene            1..8301
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /note="oxysterol binding protein-like 6"
                     /db_xref="GeneID:99031"
                     /db_xref="MGI:MGI:2139014"
     exon            1..182
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            183..348
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            349..588
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            589..844
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     CDS             743..3622
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /note="isoform b is encoded by transcript variant 2;
                     OSBP-related protein 6; oxysterol-binding protein-related
                     protein 6"
                     /codon_start=1
                     /product="oxysterol-binding protein-related protein 6
                     isoform b"
                     /protein_id="NP_001277662.1"
                     /db_xref="CCDS:CCDS71078.1"
                     /db_xref="GeneID:99031"
                     /db_xref="MGI:MGI:2139014"
                     /translation="MSSDEKGISPAHKTSTPTHRSASSSTSSQRESRQSIHVLERTAS
                     SSTEPSVSRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLK
                     GWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYH
                     LKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPATSTAESSPAANVSVVDG
                     KMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELS
                     KLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPPA
                     KGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLES
                     STDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQVVSEQDHNKGHSTQMARLRQ
                     SLSQALNQNAELRSRLNRIHSESTICDHVVSVNIIPSPDEPGEQIHVSLPLSQQVANE
                     SRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQI
                     LNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTL
                     QHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYE
                     CIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNV
                     TLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTLRNTKSSVCICKLTFVKVNYWNS
                     NVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRF
                     AVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEEN
                     NLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW"
     exon            845..937
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            938..1060
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1114
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1115..1228
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1229..1399
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1400..1532
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1636
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..1729
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1730..1804
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1805..1970
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1971..2104
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            2105..2212
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            2213..2350
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            2351..2438
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            2439..2692
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            2693..2830
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            2831..2894
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            2895..2973
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            2974..3118
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            3119..3263
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            3264..3390
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            3391..3513
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     exon            3514..8287
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4197..4202
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /note="hexamer: AATAAA"
     polyA_site      4214
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /note="major polyA site"
     regulatory      7181..7186
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /note="hexamer: ATTAAA"
     polyA_site      7200
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /note="major polyA site"
     regulatory      8053..8058
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /note="hexamer: AATAAA"
     polyA_site      8071
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
     regulatory      8256..8261
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
                     /note="hexamer: AATAAA"
     polyA_site      8280
                     /gene="Osbpl6"
                     /gene_synonym="1110062M20Rik; mKIAA4128; ORP-6"
ORIGIN      
        1 agaggagggg ctgcggcgcg gaggaccact ggaggcgccg cgcggccgcc gctgtccgcg
       61 ctggagacca cagctcggca caggcggcgc ccgtcctccg cgcctccgga gcctcctcca
      121 gcctgcgcgc cgggcagata gcacgggcca tctcccaccg cgacctaccg ctcgccctgc
      181 aggttcttgc tgggaaacca acaaaagaag acagttaagg caccagcagt gccaacaggg
      241 ctggcagacc gcagaggagc aagacgagct aaaggcatcc aaagccagtc cactgagaag
      301 cagttgtaat ggtgcagcca agctagaaga ctttgacaca agccgaaggc ctccagcaga
      361 aggtgtggcc cagattaaag gcgtgtacca ccacagctag atttggaact tgccctgtcc
      421 caggctggcc ttggaattca gagatctgct tgcctcagtc tcctgcgatc ttgcctgaac
      481 ctgagctttt tatggccaca gtgcctcaag atctcgatca aaaggacgtc ccttgtcaag
      541 atccaggtca gacaccagag tcctccagcc tcaagatctg gatcacaggt ggtttggact
      601 cgtcagcagt ggcctgagtt ttcctagtcc agtctgatcc gagggagatg gactaaagcc
      661 acagattgtc tgcttctctg tctgtgaatt gcaaggagga ttgggatggt cttccgtgca
      721 catccctaga ctaattgcag caatgagttc agacgagaag ggcatatccc ctgctcataa
      781 aacatccact ccgacccata gaagtgcctc gtcttcaaca tcttctcaga gggaaagcag
      841 acagagcatc cacgttttgg agagaactgc ttcatccagc acggagccct ctgtcagtcg
      901 gcagttgcta gagccggagc ccatccccct ctccaaggaa gctgacagct gggaaattat
      961 agaagggctg aaaataggcc aaaccaatgt ccagaaacca gacaggcacg agggatttat
     1021 gctgaagaaa agaaaatggc ctttaaaggg ctggcacaag cgcttttttg tcctggataa
     1081 tggaatgctg aagtattcca aggcgccact tgatatccaa aaaggaaaag tgcacgggag
     1141 catagatgtc ggactgtctg tcatgtcgat taaaaagaaa gctcggagga tagaccttga
     1201 cacggaagag cacatctatc atttgaaggt gaaatcccag gactggtttg acgcttgggt
     1261 ctccaaactg cgccatcaca ggttgtaccg tcagaatgaa attgtgaggt cgccgagaga
     1321 tgccagtttc cacatatttc ctgcaacttc gacagctgag tcctccccgg ctgctaatgt
     1381 ctctgttgtg gatggaaaga tgcagcccaa cagctttcca tggcagtcgc cattaccatg
     1441 cagtaacagc ctccctgcga cctgcacaac tgggcagagt aaagtggcag cctggctgca
     1501 ggactcagaa gaaatggaca ggtgtgcaga agatcttgca cactgccagt caaaccttgt
     1561 ggaacttagc aagctcctgc aaaacttgga gatccttcag agaactcagt cggcgcctaa
     1621 cttcactgac atgcaggcta actgtgtaga tatttcaaag aaagacaagc gggtcacaag
     1681 acgctggagg acaaaaagtg tcagcaaaga tacaaaaata cagctccagg aagggccacc
     1741 tgcgaagggc cagttcaaca caactcggcg ccggcagagg ctagcggcag cagtggctac
     1801 aacagttcct ttcagcgcca ccatgtcacc cgtgcgtctg cactcctcca accccaacct
     1861 ttgtgcagac attgagttcc agacccctcc tagccacctc accgaccctc tggaaagttc
     1921 cacggattat accaagctac aagaagaatt ttgtctaatt gcacagaaag tgcattctct
     1981 tctgaagtct gcatttaaca gcatagctat agagaaggag aagctgaagc aggtggtctc
     2041 ggagcaagat cacaacaaag gccacagcac acagatggcc agactccggc agtcactgtc
     2101 acaggcactt aaccagaacg ctgagctccg gagtcggctg aacagaatac actcagagtc
     2161 taccatttgt gatcacgttg tcagtgtaaa tattatccct agccccgatg agcctggtga
     2221 gcaaatccat gtcagcctcc ctctgtcaca gcaggtggcc aacgagagcc gcctctccat
     2281 gtcagaatcc gtgtcagaat tcttcgatgc ccaagaggtg ctcctgtctg caagctcatc
     2341 agagaatgag gcttctgatg atgagtccta catcagcgac gtgagtgaca acatatctga
     2401 ggacaacacc agtgtcgccg acaacatttc tcggcaaatc ctgaatgggg agctcacagg
     2461 aggcgccttc cgcaatggcc gtcgcacctg cctgcctgct ccttgcccgg acaccagtaa
     2521 cattaacctg tggaatatct tgaggaacaa cattggcaaa gacctgtcga aggtctccat
     2581 gcccgtggaa ctcaacgagc ccctcaacac cctgcagcac ctctgtgagg aaatggaata
     2641 cagtgagctc ctggacaagg cctcagagac cgacgacccc tacgagagga tggttctcgt
     2701 cgctgccttt gcagtctcag ggtactgttc cacctacttc cgagcaggaa gcaagccatt
     2761 caatccggtc ctgggggaga cctatgaatg cataagagaa gataaggggt ttcggttctt
     2821 ctcagaacaa gttagccatc atccacccat ttctgcctgt cactgtgaat ccaagaattt
     2881 tgtgttttgg caagatatca gatggaaaaa taagttctgg ggaaagtcca tggaaatcct
     2941 gcctgtcgga accctgaacg tcacgcttcc aaaatatggg gattactatg tgtggaataa
     3001 agtcaccacg tgcatacaca atatcctgag tgggaggaga tggatcgagc actacggtga
     3061 agtgaccctt agaaatacca aaagcagtgt ttgcatttgc aaactcacgt ttgtcaaggt
     3121 gaattactgg aactccaacg tgaatgaagt ccagggggtg gtgatagacc aggaggggaa
     3181 ggtggtgcac cggctgtttg ggaaatggca cgaaggactc tactgcgggg tggccccctc
     3241 ggcaaagtgc atctggagac caggttctct gccaaccaac tatgagctct actatggctt
     3301 tacaagattt gctgtggagc tcaatgagtt ggaccccgtc ctgaaggacc tccttccccc
     3361 cacagatgcc cgattccggc cagatcaaag gtttttggaa gaagggaacc tagaagccgc
     3421 agccgcagag aaacaaagag ttgaggaact ccaaagatcg cgaagacgct acatggagga
     3481 aaacaacctt gaacatatac caaaattttt taaaaaagtt attgatgcaa atcaaagaga
     3541 agcctgggtt tctaacgaca cctactggga gcttcgaaag gaccctgggt ttagcaaagt
     3601 agacagcccc gttctttggt aaactggaga catagagcta gccaatatcc cacactcgga
     3661 atgaataaat aactatgcac aattatgttt cttatagcta cgcgtggttt ctgggtcgac
     3721 tgaaaagctc ccattggctt ttctattcat ctttataatg gattttcaaa agtgcattag
     3781 acaaggctcc taaccacttt tggatccttt ctgttttgct gcaaccatat tccttaaata
     3841 aataaataaa taaataaata aaacccatgc cctcctcgga aagcagccta aaagaaggag
     3901 aatataaaat ccaaagtcgg gagagtcaga aaagaagatg aaactgtaac aggcgcttca
     3961 agctgatcag gagagtttta aatgatgtac aaactacacg ttccgtctgc tgtctgaaag
     4021 cgtcatccca taccttagga gctccggggc cgtagtcggt tagttcagac ttgaagtgtg
     4081 ttcttttgat gtggtgtgct tgttctcagc ctcgtgaaaa tcgacaacgc gatgcttccc
     4141 gaaacccact ccatctttac gacattgttc atgccttaag aaatgcaaag atgtacaata
     4201 aactgttttc taaatgtgtg ctcataggtg tatgtgaagg acagagtgct ggcgtgattc
     4261 actttcttgg tcagaaggtt gattcagctg atagaaggat taaatgaggg aaaaacacac
     4321 tttcctttgc taagtcagtt ctgctgtggt ggatctgagg ggcaagaggg ctaaggtact
     4381 gtatcctaag ttagatctct gtatccaggt cgttctttaa gttcctgtcc tatgtccaga
     4441 tagtaagcca tccctcctcc gtctgacctc acagtgtgcc ctggtatttg gcaaaagttg
     4501 tatctgattt ggacgcccgt catcagtgtt aaacttcagt aggaagtaac aaagcccagt
     4561 ttctgcctgg gctgggtggt accacaaagc acacaggcca tagaacacat ccctggctca
     4621 tgcccgccac tcgacactgt tgcgattcca tggagaacga aagcttattt gcattatgta
     4681 aatggatcct atgcataatc atgtttcttt tttaaaaaaa atcaagcggt tccatatgat
     4741 acacggttac atattaagca tctaccttgc taagggcaga tatataaaac ttaggcttaa
     4801 aaaaaagtaa tccattccaa aggtggggtc aggcaaggtt tgatttcaat ccttgaggtt
     4861 ttgtttttcc tccacgggta cacagaggct tttgtaggaa gcttgcattg gcgtttttaa
     4921 gttcttgcat gtacatgaca atataaacac ccgtatgttt tttaaaaaaa aatctcttaa
     4981 gggggcttcc tagagaatta gaaacttata tatattttat tgttagagtt ttattcttag
     5041 attcttacca tctgaattta agtgttactt tagactctga taacaaggtt agtgacattt
     5101 tatattttgt taagaggtat ctatcaatct cggtgttatt tctcccccct ccccgccccc
     5161 gcaaagtatt cctaataatg gctaactcac cataaaaccc aaaccttttg tgaacatgga
     5221 gggaaatcca gagtttcccc tagatggagc aatattttag ttatccccaa attcatctcc
     5281 ccattcatgt acaccatgca cacagctgtt agtcattcga atgaaacttc gctctccaaa
     5341 gagttcccga agtcagagcc agagccaggc ttccgcttac acggctttct ccatgtgctc
     5401 ctgagtccta ggtgactcgc cctgcagttg caaaaccttc ccccgtgtca cggactactt
     5461 tttttctcgg ttcaacccga tgctgtttta tcagtgcatc tctagttatg tctgatttta
     5521 tattgagtta ggacttaatt acagtcccgt ggacctcctc ataaaagctg gttctcctcc
     5581 aactgagaaa gcttacagta caatttaaag tgggtctcgc ctgcacttac tagtgtctga
     5641 cgaaacagtc ttacatctgc ctaagtaata gaagagccct gcagaataga gatgccacaa
     5701 ggagggactg cgaaggtgag gtgatcaaaa cacaatagga gatgtccatt tagtaaagga
     5761 cagaaggccc aggacacagc agggaagtaa agacagctcc caggtttgga ttaactgaga
     5821 agaaaggaga aacaacagat gaagcctttg tagtcagata gtaaggttaa gatgacaaat
     5881 aagataaggt cagatctacc cggaaactct aataagaatt tcaggatgca aacgagagaa
     5941 gcatgggatt aattacaatc acattgtatg gcatcctcca ttttgaatct gtttggagat
     6001 tttggttccc ccgggtgtga ccattatgtt gtcaggtctc gtctcaatca cgtcatcagt
     6061 taggcttcaa attcccccac ccccacccca gcacccgact cacccatctc caatggaaca
     6121 ctcacttgtc ttgctgaaat ggccttgtcc tttttgttca cacagtgatt ataaagaact
     6181 ctattgaaat ttcatttaca tgacatttca gctattaaac ctaaatgaca agagggtgga
     6241 gtggtatagc ttattctctt gataaaaaat gtgatgtagc ccttggaatt ttacataaac
     6301 cactatattt gggagatagt ggttttctgt caaagggccg taggaaggct tagtatgcct
     6361 gtgttctttt ccatgcttta ttttcaaagc tccctcccct ctggcaaaat tgtcctgaga
     6421 gtgacagtga ccctgagggg tttgccagac tgggctgact ggtcagtacc aacctttgct
     6481 gaggctcacc aaaattggat cattttgatg ctgaatgctg ttaaccaagg tgtaaatgta
     6541 ctcttcagtg ttgctgatct ttcttatttt ttaattgtca ttatttttct tgggttattt
     6601 taaaatgatg tccatgttct ctccaggtag ctgtaaaaaa taaataaaat aaacttcatt
     6661 taagatacct gttagtgcta catgtcagtt gtatgtgatt gcagggtcaa atgtcattct
     6721 tctgcctgag ggaaaccaag gaaattgtgg tacagaggcc accaacttgt caacttccca
     6781 aatcttttgt gctcaagctc ttgattcttc tggccttgtg ttattctgca ttagcactta
     6841 ccagtcatta gatcctgttc taatggacta gcatggagct cagagaggga gagacgctct
     6901 aggaaggaaa ccctgattaa cgtgtttagt ttagtagtaa agaacatttt ttgttactct
     6961 tctgtgggtt taattatcca tcctgtttaa tgctgttctc tgtcatccta gaaaataaag
     7021 cgtttgtggg agcagagctc cgcccagcag ggggcagagc agatgtttgc acttggctca
     7081 gtatgttatg aatgtggcac agtaaataaa gtttgtgtac agaatattag tttatttcta
     7141 tgagagcaat tatgttcagg atatataaaa aatgtatcta attaaaccat tacggatcta
     7201 ttttgtgctc tagaaatgtt cttttttttg ggttgggggg agtgtctata gagctaaaag
     7261 taaaatgttg atgtgttctc atgggtttgg tttcgtctcc caaatgctcc gtggcttttg
     7321 ggaaagactc catatcaccc caggaatcta tcttaattga gtttggtttg taaacacttc
     7381 tactttgaaa gttgtgcatt gtgtggctcc ttctctgaaa cagaaactag ctttattaac
     7441 aacatcttca gtacctcttc tgcctgtcac ggagatgtgg aacctttctg cagtggccgc
     7501 tttcaaaaag agaatggcaa attgcattgg atgggtttgg cttcattctt ctaacctggg
     7561 atctaaagga tggataaatg ctgtgatgaa gtaacatgcc ctacatccta agtagatcag
     7621 gcccttagga cagacagaca gacagacaga cagacagaca tctggcagat gcctcgtctg
     7681 gaagagaatt ggtgttgtac tcttgcattg gcttttcaaa acaacaagct tgtctctcta
     7741 tcctctggtc cttacaagca gaaggggaga tgctgctggg taccatgtca ttgtctgtga
     7801 aatgggctgt cttcatgtgt aatctcagtc attcggtatt agaaactgct tcattcattt
     7861 tcctcatgaa cagtattaat tcttcatgag ttaaaaggtt ccttatatac acatattatg
     7921 agttattttc caaactgata gaaaaaaaaa agttaaccaa aagttctcag tttccataaa
     7981 ttttgtttct atctgtacct tcctttccaa aatgagttaa ttgtaaagaa aaggatatta
     8041 aatttttggt aaaataaagt ggaatcctgt gtggggtccg tctgcttctt ctctcagcat
     8101 tagatcagat gaggaaggga actgaactct tagacaggac gatgataaaa tcactgctcc
     8161 cttacatgtc tgctctccct cagtgtttca tctcaggcct tcgggaacta aaatgtttgc
     8221 tgtgcttttt aaaaagctgg ataaaaatgt tatataataa atgtcacacg ttgaaactga
     8281 tacacaaaaa aaaaaaaaaa a
//
