LOCUS       NM_015824               6313 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus origin recognition complex, subunit 3 (Orc3),
            transcript variant 1, mRNA.
ACCESSION   NM_015824
VERSION     NM_015824.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6313)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6313)
  AUTHORS   Jaremko,M.J., On,K.F., Thomas,D.R., Stillman,B. and Joshua-Tor,L.
  TITLE     The dynamic nature of the human origin recognition complex revealed
            through five cryoEM structures
  JOURNAL   Elife 9, e58622 (2020)
   PUBMED   32808929
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6313)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6313)
  AUTHORS   Ma,S., Kwon,H.J., Johng,H., Zang,K. and Huang,Z.
  TITLE     Radial glial neural progenitors regulate nascent brain vascular
            network stabilization via inhibition of Wnt signaling
  JOURNAL   PLoS Biol 11 (1), e1001469 (2013)
   PUBMED   23349620
REFERENCE   5  (bases 1 to 6313)
  AUTHORS   Xie,L., Hoffmann,A.D., Burnicka-Turek,O., Friedland-Little,J.M.,
            Zhang,K. and Moskowitz,I.P.
  TITLE     Tbx5-hedgehog molecular networks are essential in the second heart
            field for atrial septation
  JOURNAL   Dev Cell 23 (2), 280-291 (2012)
   PUBMED   22898775
REFERENCE   6  (bases 1 to 6313)
  AUTHORS   Ma,S., Kwon,H.J. and Huang,Z.
  TITLE     A functional requirement for astroglia in promoting blood vessel
            development in the early postnatal brain
  JOURNAL   PLoS One 7 (10), e48001 (2012)
   PUBMED   23110156
  REMARK    GeneRIF: Data indicate that conditional deletion from glial
            progenitors of orc3, a gene required for DNA replication,
            dramatically reduces glial progenitor cell number in the
            subventricular zone and astrocytes in the early postnatal cerebral
            cortex.
REFERENCE   7  (bases 1 to 6313)
  AUTHORS   Kwon,H.J., Ma,S. and Huang,Z.
  TITLE     Radial glia regulate Cajal-Retzius cell positioning in the early
            embryonic cerebral cortex
  JOURNAL   Dev Biol 351 (1), 25-34 (2011)
   PUBMED   21185282
REFERENCE   8  (bases 1 to 6313)
  AUTHORS   Miyake,Y., Mizuno,T., Yanagi,K. and Hanaoka,F.
  TITLE     Novel splicing variant of mouse Orc1 is deficient in nuclear
            translocation and resistant for proteasome-mediated degradation
  JOURNAL   J Biol Chem 280 (13), 12643-12652 (2005)
   PUBMED   15634681
  REMARK    GeneRIF: mouse Orc1, Orc2, and Orc3 each exist in two
            alternative-splicing variants and naturally occurring Orc1B lacks a
            functional domain that is essential for nuclear translocation and
            proteasome-dependent degradation
REFERENCE   9  (bases 1 to 6313)
  AUTHORS   Springer,J., Nanda,I., Hoehn,K., Schmid,M. and Grummt,F.
  TITLE     Identification and chromosomal localization of murine ORC3, a new
            member of the mouse origin recognition complex
  JOURNAL   Cytogenet Cell Genet 87 (3-4), 245-251 (1999)
   PUBMED   10702681
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB663298.1, AK045388.1, AK086579.1 and AK041216.1.
            
            On Apr 21, 2009 this sequence version replaced NM_015824.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK086579.1, AK045388.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                BB663298.1         1-25
            26-1110             AK045388.1         1-1085
            1111-3045           AK086579.1         1114-3048
            3046-6313           AK041216.1         628-3895
FEATURES             Location/Qualifiers
     source          1..6313
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 16.81 cM"
     gene            1..6313
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /note="origin recognition complex, subunit 3"
                     /db_xref="GeneID:50793"
                     /db_xref="MGI:MGI:1354944"
     exon            1..78
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..2181
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /note="isoform 1 is encoded by transcript variant 1;
                     origin of replication 3 homolog; origin recognition
                     complex subunit Latheo"
                     /codon_start=1
                     /product="origin recognition complex subunit 3 isoform 1"
                     /protein_id="NP_056639.3"
                     /db_xref="CCDS:CCDS18028.1"
                     /db_xref="GeneID:50793"
                     /db_xref="MGI:MGI:1354944"
                     /translation="MHTGPRTMATSSVSKGCFVFKPDFKKRKVFVPIEDYFNNEELDS
                     EDSKLRFETYSLLWQRMKSETEQLQEELNENLFDNLVDFLQKSHPEFQKNSRDWGSQM
                     KFREIPTAALILGVNVTDHDVILRSLTETLQNNVTPYVVSLQAKDCPDVKHFLQKFTS
                     QLMDCCVDRHSKEVTSGKALKKTNYSMDSLCSWYSAVTQKADHKVTIKKRTASGHWRS
                     PPVVLILKSMESFTSKVLQDFITISSQHLHEFPLILIFGIATSPVIIHRLLPHSVSSL
                     LCVELFQSLSCEQHLTVVLDKLLLTPQFPFKLSKKALQVLTNIFLYHDFSIQSFIKGI
                     KLSLLEHFYSQPLSVLCCDLSEAKKRVNVFSVSQCENIRRLPSFRRYVENQPLGKQVA
                     LLTNETFLKEKTQSLLEDLHVYHINYFLVLRCLHNFTSSLPKYPLGRQIRELYCTCLE
                     KKIWDSEEYKSALQLLRMLAKDELVSILQRCIEVLDSSTEKQLGNTTQKIKDFLTQFQ
                     NLDADSKEEEDACGSQPKGLQKTDLYHLQKSLLEMKELRRTKKPTKFEMLRENVMNFI
                     DNLVRDYLLPPESQPLHEVVYFSAANTLREHLNAAPRIALHTALNNPYYYLKNEELEG
                     CIPNTAPDICIAYKLHLECSLLINLVDWAEAFATVVTAAEKMDANSTVSEEMSEVIHA
                     RFIRAVSELELLGFIKPTKQKTDHVARLTWGGC"
     exon            79..133
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            134..231
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            232..376
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            377..481
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            482..630
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            631..764
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            765..924
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1038
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1172
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1236
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1353
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1354..1433
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1434..1567
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1568..1647
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1648..1745
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1746..1887
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1888..1995
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            1996..2075
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     exon            2076..6313
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2265..2270
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /note="hexamer: AACAAA"
     polyA_site      2298
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /note="major polyA site"
     regulatory      2904..2909
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /note="hexamer: AATACA"
     polyA_site      2925
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
     regulatory      3043..3048
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /note="hexamer: ATTAAA"
     polyA_site      3062
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
     regulatory      3777..3782
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /note="hexamer: AATAAA"
     polyA_site      3799
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
     regulatory      5859..5864
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
                     /note="hexamer: AATAAA"
     polyA_site      5880
                     /gene="Orc3"
                     /gene_synonym="Orc3l"
ORIGIN      
        1 ttccgccagg gcgcgcggaa gtgtggagtg cgcatgcaca cggggccgcg gactatggcc
       61 acctcctccg tgtctaaggg ctgctttgtg tttaaaccag acttcaaaaa aagaaaggtc
      121 tttgtgccaa tagaggatta ttttaataat gaggaacttg actctgagga cagtaaactt
      181 cgatttgaaa catatagctt gctatggcaa cggatgaaat ctgaaacaga gcaattacag
      241 gaggaattaa atgaaaatct gtttgataac ctagttgact ttctgcagaa gtcccatcct
      301 gaattccaga aaaattcaag agactggggc tctcaaatga aattcagaga aattccaaca
      361 gctgctctta ttcttggtgt gaatgtcacg gatcatgatg tgatactcag aagtctaaca
      421 gagacccttc agaataatgt cacaccatat gtagtctcac tgcaagctaa ggattgtccc
      481 gatgtgaaac attttttaca aaagtttacc tcacagttga tggactgctg tgtagacagg
      541 cattccaagg aggtgacaag tggtaaggcc ctgaagaaga caaattattc aatggattcc
      601 ctttgtagtt ggtattcggc agtcacacag aaagcagacc acaaagtgac aatcaaaaag
      661 aggacagcat ctggccattg gcggtcccct cctgtggtgc ttatcttaaa gagcatggag
      721 agtttcacca gcaaagtcct ccaagacttc ataactatca gcagtcagca tctgcatgag
      781 tttccgctaa ttctgatttt tgggatcgcc acatctcctg ttattatcca ccgactgctt
      841 cctcattcag tgtcatcgct gttgtgtgta gaactgttcc agtctctgtc ttgcgagcaa
      901 cacctgacag tagttcttga taagctactt cttacacctc agtttccctt taaactaagt
      961 aaaaaggcat tacaggttct gaccaacatc tttttgtatc atgatttctc aattcaaagc
     1021 ttcatcaaag gaattaagct ttctctacta gaacattttt attcccagcc cctaagtgtt
     1081 ctgtgctgcg atctctcaga agccaagaaa agagtaaatg ttttctcagt tagtcaatgt
     1141 gaaaacatcc gccgccttcc ttcatttagg aggtacgtgg aaaaccagcc tttgggaaag
     1201 caagtggcac tgctgacaaa tgagaccttc ttaaaggaga aaactcaatc attgctggaa
     1261 gacctgcatg tttaccatat caattacttc cttgtcttga gatgtcttca taattttacc
     1321 tcttctcttc ccaagtaccc actgggtcga cagattaggg agctgtattg cacatgttta
     1381 gaaaagaaga tatgggattc ggaggagtac aagtcagcct tgcagctgct gagaatgctg
     1441 gcaaaggatg aactggtgag catacttcag cgctgtattg aggttttaga ttcctctact
     1501 gaaaagcagc ttggcaacac aacacagaaa ataaaggatt tcctgaccca gtttcagaac
     1561 ctcgatgcag atagcaaaga ggaagaggat gcctgtggat cacagccaaa ggggctgcag
     1621 aagacagacc tgtatcacct tcagaagtcc ttactagaaa tgaaagagct aaggagaact
     1681 aagaagccaa ccaagtttga aatgctcaga gaaaatgtta tgaacttcat cgacaactta
     1741 gtgagagact accttctgcc tcctgagagc cagcctctgc atgaggtagt gtacttcagt
     1801 gctgccaaca cactccgtga gcacttaaat gctgctccaa gaatcgctct tcacactgca
     1861 ctcaacaacc catactatta cctgaagaat gaagaactgg aaggatgtat tccaaatact
     1921 gcccctgaca tctgcatagc atacaaactg cacctggagt gtagcctgct gatcaacctc
     1981 gtcgactggg cagaggcttt tgcaacagtt gtgacagctg ctgagaaaat ggatgcaaat
     2041 tctacagtct cagaagaaat gagtgaagtt attcatgctc gatttattcg agctgtttct
     2101 gaattagaac ttttaggctt tataaaacct acgaaacaga agactgacca tgttgcaagg
     2161 cttacatggg gaggctgtta aacagcaaga gagtgaagac aagaagagtt ccatgtccaa
     2221 cttgcatatt tgtatcaaaa cgtttttgga gtacttcaaa gactaacaaa tgcataaagc
     2281 ctttatatgt tatcagtata cattgcttca ttcttgcttg tctagtgtgt aaatgctaga
     2341 acttcttacg catagctctc agcagcaccc caaacgccag cacactgtaa agttagacac
     2401 tgtaaacatc tttcaggtgt tttccttgct agaaaggctc taaaatcacc tcagcctctc
     2461 catttcttat aatcttggca acttaccagg cccaaagcta tttggcttta tacttaataa
     2521 acattcatat gaacagccac ggagacttac aaccagtaag ggccttcaca aactgctccc
     2581 ctaacttaca aaactcagaa atgtaaaggt ccagtgaaat aatatcgtat ctttcatgac
     2641 aagaacttaa gaatcagaca cataaaactc attatttaat gttcaactct caagagaatt
     2701 gtaccaaaat tgttcacaaa tgattcagag agtccatgtc cagaaaaaaa tttaaaagcc
     2761 tctgacttgt gttgcaaggt atatgcaaga ttatgatcct ttctccatgc cccccatccc
     2821 gaagtgctaa gattataagg aatttacatt atgcccagac gagaaaacag gtctttaaac
     2881 aacacaacat tttgtgcata taaaatacag aggaactggt gttaatactg gcatattttt
     2941 atcttgtctg aggcatgttt tcttttccta ggcattgcct gcatttgtgc gtgtgtgcac
     3001 attgacttct catactatca aaaggacctg taggactgaa ccattaaact gattgtgtgt
     3061 aattacttgg tatcctataa aaactcaatc cttcattgag gtgcctggca cttactagat
     3121 attttagaaa caagatcagt gttttccttg tcctttatgt agcaaagcag acctcacttg
     3181 agcaaaagta taggaatgaa aaaaactacc caggaggact tatgggtgac cccactaggc
     3241 aggcaacagc agtaaccaat atcctaggat ggggacacca agacagagac agctaggatg
     3301 gatcaggggg ttcaaataat aggaattgaa tgagtaggac aagagtgcag gtagtgaagc
     3361 tttgttttct tcggtcagaa gcaaaagggt aaagcctttc aatgatcaac acgtgtgaga
     3421 acagtgaggc ctgatgcagc aaagcaacca ctagttagct gaccaagagc agcggggttg
     3481 gtgtcactgt tgattaacta caattagatg cacatttaga tccttaaaat cccttctgct
     3541 tataaactag aagcattgct atcagtgggc tgctatggct actgctcggt ggtgggatct
     3601 ctaagaacta aggtataatg ggaagtctgc gagtgtggcc gcaaggaaaa tgggaggatc
     3661 caacagtcct ctttattctt ttgcttcctg gctgatgagc taacagttta gctctaaact
     3721 ggactctagt catgtcttct gcctcaactg atcatacgcc ttcaaaatgc aattgaaata
     3781 aacttcctga ctagataaac ctgagtattt tattgtagtt atggaaggct aattgaaaga
     3841 aacagcagca aaactgagtt tggctttggc tataacaatc aggagagatt ctggtgaaat
     3901 gctacacagt aaggtgagca gaatcttgtt tagagatcac caacgtcagc actgaagaga
     3961 ggcaaggaga tcaaactcca gcgttgaggt ttatgcttat ttgtaggtaa aaattcaaga
     4021 gaacattaaa agtgaaagga atcaggcaag tatcttagaa gccaactgaa gactttgaag
     4081 ctcatatatg aatagagtaa acaatgcggt aatcttaggt aacttggtta attgaccgag
     4141 ccaagtatca aactgaccag taagcggggg aaaaagccat atgctaatac tttataatac
     4201 ggactccata acatcacttt acagtcttaa ccaaaaggct taccccaaca ctaaaactaa
     4261 acattaataa agttcacaag tgaggaactt gctgttcttc taaaagacca gaagtgggtt
     4321 tgtagcaacc acatcagatt tttcaaaact acctagctcc aagggatcta ccaccctctt
     4381 tggcctctgt gggcacttgc acatccatgt ggacacatac aagtattaaa acttttaaat
     4441 ctgcattcta gtttataact tcaaaaagga caggtcatgt taatggtagc acaaagaaat
     4501 actcaactta gtctttccag aaagttgtaa tcttggttga atccttgtgg gggaagagag
     4561 gaggggttgg ggtgctaaaa gcatttagaa aacagagaaa tacaaatgta gacagcatct
     4621 acctcaagtg gccagcgctg aggttagaga gaagcatatg tgtttagaca acttcccaac
     4681 acagcttagc actttctact tgaaaaaatc aagtaggaaa tgacactaat ctttcaactt
     4741 ctgtgatgag tgttttccta acaagttgag ggctatattt gaaagataac gtgaagattt
     4801 ttgttgacat aatgggaaag gggagagata ccattaacac tctagaatgt acagatacat
     4861 cccaaagtac caatagcatt gaggctgaaa tctaagtgtg agattagttc actttacatc
     4921 cagctgcccc attctataac ttgtgtttct tgtgtactaa tggatttgga actgcctgac
     4981 aatcttgtga aagccacaga gcacactctg ggtgcttatt tttaaatgag gttattagta
     5041 agttaaaaat gaaatattgt gttttaagat tagtctaatg acaggaagta tgctattaaa
     5101 attcaaaggg agccagagag gtagctcagc agttaagaat gtttgccact cttgcagagg
     5161 acttaaggga ttttggttcc tagcctcaac atgggcagct caacaactgg ctgtcttatg
     5221 gcctcaggca cataagcgta tacaaataaa atcttttttt tttttttaaa attgaaaata
     5281 attcactgag caagactgag ggggtggcct ttaacctcta atcctgtctc aactaccaag
     5341 atgacaaatg tgtggttagt actttcagct ttctcactac tttgtataca tttaatttag
     5401 tcattcactg tgatattatt taatgtttta tgtatgtgtg cttgcctgag tatatatgtg
     5461 tgtactgtgt gcatggagtt cagaaaaggc atcagttggt gagctgttat ataggttctg
     5521 ggaaccaaac aagggtcttc caaaaaagca acctgagctc ttctgagcct ctctccagcc
     5581 cttaagatgt taactttttc atctcaacag tacctaggat tttctaaatc ttaacaaggc
     5641 ttgtctagat cagtttagcc tgtaagcatg tctgtgagtg actgaattgc cttaaccaat
     5701 caggaagaga gccaaccaga agtgggtgga accatccact aaacttagta cttaaacatt
     5761 tactgatggc tctctgctct tacttgtggc tacaagttcc tgcagttttg atttccccac
     5821 agtgatagac tgcaacctgg gattttgagg taaagtaaaa taaacactta ataccctaaa
     5881 ctgctttgtg tggggttact ttatcacatc aactagagcg accatgtgtt catctatcac
     5941 attgttcaaa aaaatcaaaa ctggattcaa aggaaaggtc tacagctgtt ttagatcttg
     6001 ttatagaaca tgctgttata cagcaagtta cagaagcagt tttgaatcat aatttctgaa
     6061 aacagcattt aaaaggtaaa taatgccaga aaactaactt tgtgttgatt tctagaaaat
     6121 acttaacatt taaacactac tttattccaa tactacccat gtgtacaatt cggaaacagg
     6181 cagaatagaa gtaaatgttt tatttttcca actaaactcc agtgctacaa gggtagtaaa
     6241 acaataatac actggggagg aggtgcagca ataaacattt gttaaaaaga ctgatagaat
     6301 aaataaaact acc
//
