LOCUS       NM_146787               1960 bp    mRNA    linear   ROD 26-OCT-2024
DEFINITION  Mus musculus olfactory receptor family 8 subfamily B member 53
            (Or8b53), mRNA.
ACCESSION   NM_146787
VERSION     NM_146787.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1960)
  AUTHORS   Olender,T., Jones,T.E.M., Bruford,E. and Lancet,D.
  TITLE     A unified nomenclature for vertebrate olfactory receptors
  JOURNAL   BMC Evol Biol 20 (1), 42 (2020)
   PUBMED   32295537
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1960)
  AUTHORS   Cho,T., Lee,C., Lee,N., Hong,Y.R. and Koo,J.
  TITLE     Small-chain fatty acid activates astrocytic odorant receptor
            Olfr920
  JOURNAL   Biochem Biophys Res Commun 510 (3), 383-387 (2019)
   PUBMED   30711253
  REMARK    GeneRIF: Olfr920 is expressed in primary cortical astrocytes and
            deorphanized to reveal isobutyric acid as a ligand.
REFERENCE   3  (bases 1 to 1960)
  AUTHORS   Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
            Walker,M., Williams,E.M. and Trask,B.J.
  TITLE     Odorant receptor expressed sequence tags demonstrate olfactory
            expression of over 400 genes, extensive alternate splicing and
            unequal expression levels
  JOURNAL   Genome Biol 4 (11), R71 (2003)
   PUBMED   14611657
REFERENCE   4  (bases 1 to 1960)
  AUTHORS   Young,J.M., Friedman,C., Williams,E.M., Ross,J.A., Tonnes-Priddy,L.
            and Trask,B.J.
  TITLE     Different evolutionary processes shaped the mouse and human
            olfactory receptor gene families
  JOURNAL   Hum Mol Genet 11 (5), 535-546 (2002)
   PUBMED   11875048
  REMARK    Erratum:[Hum Mol Genet. 2002 Jul 1;11(14):1683.]
REFERENCE   5  (bases 1 to 1960)
  AUTHORS   Zhang,X. and Firestein,S.
  TITLE     The olfactory receptor gene superfamily of the mouse
  JOURNAL   Nat Neurosci 5 (2), 124-133 (2002)
   PUBMED   11802173
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC069561.37.
            
            On Sep 9, 2009 this sequence version replaced NM_146787.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK039833.1, ERR3363658.21523.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-250               AC069561.37        168342-168591
            251-1960            AC069561.37        170700-172409
FEATURES             Location/Qualifiers
     source          1..1960
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 20.9 cM"
     gene            1..1960
                     /gene="Or8b53"
                     /gene_synonym="MOR165-6; Olfr920"
                     /note="olfactory receptor family 8 subfamily B member 53"
                     /db_xref="GeneID:258783"
                     /db_xref="MGI:MGI:3030754"
     exon            1..250
                     /gene="Or8b53"
                     /gene_synonym="MOR165-6; Olfr920"
                     /inference="alignment:Splign:2.1.0"
     exon            251..1960
                     /gene="Or8b53"
                     /gene_synonym="MOR165-6; Olfr920"
                     /inference="alignment:Splign:2.1.0"
     CDS             787..1719
                     /gene="Or8b53"
                     /gene_synonym="MOR165-6; Olfr920"
                     /note="olfactory receptor MOR165-6;
                     GA_x6K02T2PVTD-32458442-32459374"
                     /codon_start=1
                     /product="olfactory receptor 920"
                     /protein_id="NP_666998.2"
                     /db_xref="CCDS:CCDS23025.1"
                     /db_xref="GeneID:258783"
                     /db_xref="MGI:MGI:3030754"
                     /translation="MALINGSVVTEFILLGLTDQPDLQVPLFLVFLLMYMITALGNLT
                     LIILIVLNSHLHTPMYFFLFNLSFVDFCYSSVIIPKMLMNFILKKNFISYVGCMTQFY
                     LFGFCVILECYILTSMAYDRYVAICNPLLYNIVMSPKMCSYLMLGSYLMGFSGAMIHT
                     GCVLRLSFCDGNIINHYFCDLLPLLQLSCTSTYVNEIEVLIVAGKDIIVPTVIIFISY
                     GFILSSIFQMKSTKGMSKAFSTCSSHIIAVSLFFGSGAFMYLKPNSTGTMNNGKIPSI
                     IYTILIPMMNPLIYSLRNKDVKVALRKTLRKKIL"
     regulatory      1816..1821
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Or8b53"
                     /gene_synonym="MOR165-6; Olfr920"
                     /note="hexamer: AATAAA"
     polyA_site      1837
                     /gene="Or8b53"
                     /gene_synonym="MOR165-6; Olfr920"
                     /note="major polyA site"
ORIGIN      
        1 ttctgaaaaa aggggcgtca aaaaaaagaa gtgaaaagaa tgacaacata tcgaggaata
       61 tatatgtata tacatacaca tttatttata taacaacaac cagtgaaaaa gaagaccatg
      121 aatttgagag agagaacaag aaggaaaatt atggtgctcc aatgttgatg attttccatt
      181 ttctttacat acttgttata tggtcttccc cctcgggatc ttgtcactga agaacaacct
      241 gctggatcag agacttcaca ttgatacagt ccaagaacca gagctgtgcc attttcttct
      301 cattttgtaa agtcctatga ttccaaagaa atttccagat gcatggccaa gacaaagtgt
      361 tttccagagt tagtaaatac ttctgttgtg gtgcttaaat tagtaagttc actctgcatg
      421 tacagttctt acaccataga acttaatgtg agcatagcag aatgctcacc attcctagat
      481 tctggttatt ttgtttaaat tagaaacagt gttcatggtt ctaacacatc cagagttcag
      541 tctggatgga ttgtaaaatt cagttagtag agtttctact tgtgtcacag agatgataaa
      601 acaaaacaaa aaaaaaatag gaagataaga taagggagat gctgttgtgt gcatcatact
      661 tcttgctttt cccttgactt tgattgtagc catctaggat ttgacagccc cactctcagg
      721 attagagatc ttcatgatcc tttaattcac catttattta tatttcacaa gatatcttat
      781 agaagtatgg ctttgataaa tggctctgtg gtaacagaat tcattctctt gggattaaca
      841 gaccagcctg accttcaagt acccctgttc ctggtctttc tattaatgta catgataact
      901 gcattgggga atttgacttt aattattctc atcgtgctga attctcacct tcatacccct
      961 atgtattttt ttctttttaa cttgtccttt gtggactttt gttactcttc tgtaattata
     1021 ccaaaaatgc tgatgaactt tattctaaag aaaaatttta tctcctatgt gggttgtatg
     1081 actcagttct acttatttgg tttctgtgtc attttggagt gttatattct cacatcaatg
     1141 gcctatgatc gttatgtggc tatctgcaat ccactcttgt ataacattgt catgtctccg
     1201 aagatgtgtt cctatctcat gcttggttca tatttgatgg ggttttctgg tgctatgatc
     1261 cacactggat gtgtcctgag actgtcgttc tgtgatggca acatcatcaa ccactatttc
     1321 tgtgatctcc tccctttgct gcaactctcc tgcaccagca cctatgtcaa tgagatagag
     1381 gtgttaattg tagcagggaa ggatatcatt gtgcccactg tgatcatctt tatctcatat
     1441 ggcttcatcc tttccagcat atttcaaatg aaatccacta agggcatgtc aaaggccttc
     1501 agcacctgta gttcccacat aattgctgtc tctctgttct ttggatctgg tgcatttatg
     1561 tatcttaaac ccaactcaac tggaacaatg aacaatggaa agataccttc aataatttat
     1621 accatcttaa ttcctatgat gaatccatta atttatagct tgagaaacaa agatgttaaa
     1681 gttgccttga gaaaaacttt gagaaagaaa atcttgtaat cagaaactgt aatttatttt
     1741 agttggaaat tgtttttctt tgtcatttta atgaaaacac tttcctggtc ctaaagtctg
     1801 acaaaaaaat aaataaataa aacatttgca accctcatat caactagcag taaaccccct
     1861 catatgcttt tgctgaatag acaaaatatc acagtgccat ataaattctg aactctctac
     1921 ccatagatta ctgcagttct caggccccat cagagatgtt
//
