LOCUS       NM_146328               1106 bp    mRNA    linear   ROD 24-OCT-2024
DEFINITION  Mus musculus olfactory receptor family 5 subfamily V member 1
            (Or5v1), mRNA.
ACCESSION   NM_146328
VERSION     NM_146328.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1106)
  AUTHORS   Olender,T., Jones,T.E.M., Bruford,E. and Lancet,D.
  TITLE     A unified nomenclature for vertebrate olfactory receptors
  JOURNAL   BMC Evol Biol 20 (1), 42 (2020)
   PUBMED   32295537
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1106)
  AUTHORS   Gaudel,F., Stephan,D., Landel,V., Sicard,G., Feron,F. and
            Guiraudie-Capraz,G.
  TITLE     Expression of the Cerebral Olfactory Receptors Olfr110/111 and
            Olfr544 Is Altered During Aging and in Alzheimer's Disease-Like
            Mice
  JOURNAL   Mol Neurobiol 56 (3), 2057-2072 (2019)
   PUBMED   29984401
  REMARK    GeneRIF: Olfr110/111 and Olfr544 proteins are mainly expressed by
            neurons in cortical and hippocampal regions and, to a lesser
            extent, by glia and endothelial cells. expression of the mRNA
            encoding for Olfr110/111 tends to increase with age in both the
            cortex and hippocampus of wild-type and transgenic mice. Moreover,
            Olfr110/111 transcript expression is markedly impaired in the brain
            of Alzheimer's disease-like mice.
REFERENCE   3  (bases 1 to 1106)
  AUTHORS   Amadou,C., Younger,R.M., Sims,S., Matthews,L.H., Rogers,J.,
            Kumanovics,A., Ziegler,A., Beck,S. and Lindahl,K.F.
  TITLE     Co-duplication of olfactory receptor and MHC class I genes in the
            mouse major histocompatibility complex
  JOURNAL   Hum Mol Genet 12 (22), 3025-3040 (2003)
   PUBMED   14506126
REFERENCE   4  (bases 1 to 1106)
  AUTHORS   Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
            Walker,M., Williams,E.M. and Trask,B.J.
  TITLE     Odorant receptor expressed sequence tags demonstrate olfactory
            expression of over 400 genes, extensive alternate splicing and
            unequal expression levels
  JOURNAL   Genome Biol 4 (11), R71 (2003)
   PUBMED   14611657
REFERENCE   5  (bases 1 to 1106)
  AUTHORS   Young,J.M., Friedman,C., Williams,E.M., Ross,J.A., Tonnes-Priddy,L.
            and Trask,B.J.
  TITLE     Different evolutionary processes shaped the mouse and human
            olfactory receptor gene families
  JOURNAL   Hum Mol Genet 11 (5), 535-546 (2002)
   PUBMED   11875048
  REMARK    Erratum:[Hum Mol Genet. 2002 Jul 1;11(14):1683.]
REFERENCE   6  (bases 1 to 1106)
  AUTHORS   Zhang,X. and Firestein,S.
  TITLE     The olfactory receptor gene superfamily of the mouse
  JOURNAL   Nat Neurosci 5 (2), 124-133 (2002)
   PUBMED   11802173
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB173127.1 and BC132347.1.
            
            On Aug 4, 2009 this sequence version replaced NM_146328.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB173127.1, CB174133.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-404               CB173127.1         1-404
            405-1106            BC132347.1         349-1050
FEATURES             Location/Qualifiers
     source          1..1106
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 19.16 cM"
     gene            1..1106
                     /gene="Or5v1"
                     /gene_synonym="MOR249-2; Olfr110"
                     /note="olfactory receptor family 5 subfamily V member 1"
                     /db_xref="GeneID:258325"
                     /db_xref="MGI:MGI:2177493"
     exon            1..30
                     /gene="Or5v1"
                     /gene_synonym="MOR249-2; Olfr110"
                     /inference="alignment:Splign:2.1.0"
     exon            31..1106
                     /gene="Or5v1"
                     /gene_synonym="MOR249-2; Olfr110"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..1038
                     /gene="Or5v1"
                     /gene_synonym="MOR249-2; Olfr110"
                     /note="olfactory receptor MOR249-2"
                     /codon_start=1
                     /product="olfactory receptor 110"
                     /protein_id="NP_666440.2"
                     /db_xref="CCDS:CCDS28754.1"
                     /db_xref="GeneID:258325"
                     /db_xref="MGI:MGI:2177493"
                     /translation="MEGKNQTAPSEFIILGFDHLNELQYLLFTIFFLTYICTLGGNVF
                     IIVVTIADSHLHTPMYYFLGNLALIDICYTTTNVPQMMVHLLSEKKIISYGGCVTQLF
                     AFIFFVGSECLLLAAMAYDRYIAICKPLRYSFIMNKALCSWLAASCWTGGFLNSVLHT
                     VLTFHLPFCGNNQINYFFCDIPPLLILSCGDTSLNELALLSIGILIGWTPFLCVILSY
                     LYIISTILRIRSSEGRHKAFSTCASHLLIVILYYGSAIFTYVRPISSYSLEKDRLISV
                     LYSVVTPMLNPVIYTLRNKDIKEAVKAIGRKWQPPVFSSDI"
ORIGIN      
        1 tttctgttga atatttttga tagcagctaa actattatca atgcacctgt ttgtcaaatc
       61 cacaaaggca aaccagctga catcatggaa ggaaagaatc aaacagctcc atctgaattc
      121 atcatcttgg ggttcgacca cctgaatgaa ttgcagtatt tactcttcac catcttcttt
      181 ctgacctaca tatgcacttt aggaggcaat gtttttatca ttgtggtgac catagctgat
      241 tcccacctac acacacccat gtattatttc ctaggaaatc ttgcccttat tgacatctgc
      301 tacactacta ctaatgtccc ccagatgatg gtgcatcttc tgtcagagaa gaaaatcatt
      361 tcctatggag gctgtgtgac ccagctcttt gcattcattt tctttgttgg ctcagagtgt
      421 ctcctcctgg cagcaatggc atatgatcga tatattgcta tctgtaagcc gttaaggtac
      481 tcatttatta tgaacaaggc tctgtgcagc tggttagcag cttcatgctg gacaggtggg
      541 tttctcaact cagtgttgca cacggttttg accttccacc tgcccttttg tggtaacaat
      601 cagatcaatt atttcttctg tgacatacct cccttgctca tcttgtcttg tggtgatact
      661 tccctcaatg aactggcttt gctgtccatt gggatcctca taggctggac tcctttcctg
      721 tgcgtcatcc tttcctacct ttacatcatc tccaccatcc tgaggatccg ttcctctgag
      781 gggaggcaca aagccttttc cacctgtgcc tcccacctgc tcattgttat tctctattat
      841 ggcagtgcta tcttcacgta tgtgaggccc atctcatctt actctctaga gaaagataga
      901 ttgatctcag tgctgtatag tgttgtcaca cccatgctga atcctgtaat ttatacgcta
      961 aggaataagg acatcaaaga ggctgtgaag gccataggga gaaagtggca gccaccagtt
     1021 ttctcttctg atatataacc tctcttatgt gtgatcaaca atcttacatt agaaagttaa
     1081 attttctacc actcagttgt tgctgg
//
