LOCUS       NM_054090                942 bp    mRNA    linear   ROD 24-OCT-2024
DEFINITION  Mus musculus olfactory receptor family 5 subfamily D member 18
            (Or5d18), mRNA.
ACCESSION   NM_054090
VERSION     NM_054090.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 942)
  AUTHORS   Raja,R., Dumontier,E., Phen,A. and Cloutier,J.F.
  TITLE     Insertion of a neomycin selection cassette in the Amigo1 locus
            alters gene expression in the olfactory epithelium leading to
            region-specific defects in olfactory receptor neuron development
  JOURNAL   Genesis 62 (2), e23594 (2024)
   PUBMED   38590146
REFERENCE   2  (bases 1 to 942)
  AUTHORS   Olender,T., Jones,T.E.M., Bruford,E. and Lancet,D.
  TITLE     A unified nomenclature for vertebrate olfactory receptors
  JOURNAL   BMC Evol Biol 20 (1), 42 (2020)
   PUBMED   32295537
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 942)
  AUTHORS   Vaddadi,N., Iversen,K., Raja,R., Phen,A., Brignall,A., Dumontier,E.
            and Cloutier,J.F.
  TITLE     Kirrel2 is differentially required in populations of olfactory
            sensory neurons for the targeting of axons in the olfactory bulb
  JOURNAL   Development 146 (11) (2019)
   PUBMED   31142543
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 942)
  AUTHORS   Yuan,S., Dahoun,T., Brugarolas,M., Pick,H., Filipek,S. and Vogel,H.
  TITLE     Computational modeling of the olfactory receptor Olfr73 suggests a
            molecular basis for low potency of olfactory receptor-activating
            compounds
  JOURNAL   Commun Biol 2, 141 (2019)
   PUBMED   31044166
  REMARK    GeneRIF: The binding pocket of the prototypical olfactory receptor
            Olfr73 is smaller, but more flexible, than binding pockets of
            typical non-olfactory G-protein-coupled receptors. A molecular
            basis for reduced interaction contacts between an odorant and its
            OR and thus the typical low potency of OR-activating compounds.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 942)
  AUTHORS   Bastakis,G.G., Savvaki,M., Stamatakis,A., Vidaki,M. and
            Karagogeos,D.
  TITLE     Tag1 deficiency results in olfactory dysfunction through impaired
            migration of mitral cells
  JOURNAL   Development 142 (24), 4318-4328 (2015)
   PUBMED   26525675
REFERENCE   6  (bases 1 to 942)
  AUTHORS   Katada,S., Tanaka,M. and Touhara,K.
  TITLE     Structural determinants for membrane trafficking and G protein
            selectivity of a mouse olfactory receptor
  JOURNAL   J Neurochem 90 (6), 1453-1463 (2004)
   PUBMED   15341529
REFERENCE   7  (bases 1 to 942)
  AUTHORS   Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
            Walker,M., Williams,E.M. and Trask,B.J.
  TITLE     Odorant receptor expressed sequence tags demonstrate olfactory
            expression of over 400 genes, extensive alternate splicing and
            unequal expression levels
  JOURNAL   Genome Biol 4 (11), R71 (2003)
   PUBMED   14611657
REFERENCE   8  (bases 1 to 942)
  AUTHORS   Young,J.M., Friedman,C., Williams,E.M., Ross,J.A., Tonnes-Priddy,L.
            and Trask,B.J.
  TITLE     Different evolutionary processes shaped the mouse and human
            olfactory receptor gene families
  JOURNAL   Hum Mol Genet 11 (5), 535-546 (2002)
   PUBMED   11875048
  REMARK    Erratum:[Hum Mol Genet. 2002 Jul 1;11(14):1683.]
REFERENCE   9  (bases 1 to 942)
  AUTHORS   Zhang,X. and Firestein,S.
  TITLE     The olfactory receptor gene superfamily of the mouse
  JOURNAL   Nat Neurosci 5 (2), 124-133 (2002)
   PUBMED   11802173
REFERENCE   10 (bases 1 to 942)
  AUTHORS   Kajiya,K., Inaki,K., Tanaka,M., Haga,T., Kataoka,H. and Touhara,K.
  TITLE     Molecular bases of odor discrimination: Reconstitution of olfactory
            receptors that recognize overlapping sets of odorants
  JOURNAL   J Neurosci 21 (16), 6018-6025 (2001)
   PUBMED   11487625
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB061228.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB061228.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..942
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 49.98 cM"
     gene            1..942
                     /gene="Or5d18"
                     /gene_synonym="fascin-1; mOR-EG; MOR174-9; Olfr73"
                     /note="olfactory receptor family 5 subfamily D member 18"
                     /db_xref="GeneID:117004"
                     /db_xref="MGI:MGI:2151908"
     CDS             1..942
                     /gene="Or5d18"
                     /gene_synonym="fascin-1; mOR-EG; MOR174-9; Olfr73"
                     /note="GA_x6K02T2Q125-49527073-49526132; olfactory
                     receptor MOR174-9; olfactory receptor 73"
                     /codon_start=1
                     /product="olfactory receptor family 5 subfamily D member
                     18"
                     /protein_id="NP_473431.1"
                     /db_xref="CCDS:CCDS16322.1"
                     /db_xref="GeneID:117004"
                     /db_xref="MGI:MGI:2151908"
                     /translation="MTLSDGNHSGAVFTLLGFSDYPELTIPLFLIFLTIYSITVVGNI
                     GMIVIIRINPKLHIPMYFFLSHLSFVDFCYSSIVAPKMLVNLVTMNRGISFVGCLVQF
                     FFFCTFVVTESFLLGVMAYDRFVAIRNPLLYTVAMSQRLCAMLVLGSYAWGVVCSLIL
                     TCSALNLSFYGFNMINHFFCEFSSLLSLSRSDTSVSQLLLFVFATFNEISTLLIILLS
                     YVLIVVTILKMKSASGRRKAFSTCASHLTAITIFHGTILFLYCVPNSKNSRHTVKVAS
                     VFYTVVIPMLNPLIYSLRNKDVKDTVKKIIGTKVYSS"
     exon            1..942
                     /gene="Or5d18"
                     /gene_synonym="fascin-1; mOR-EG; MOR174-9; Olfr73"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgactctgt cagatggaaa tcacagtggg gctgtgttca ccctcttggg cttctcagat
       61 tatccagaat tgacaatccc tctctttttg atatttctca ccatctacag catcactgtg
      121 gtaggaaata ttggcatgat tgtcataatc agaattaatc ccaaactgca catccccatg
      181 tacttctttc tcagccacct ctcttttgtg gatttttgtt attcctccat tgttgctccc
      241 aagatgctgg taaatctagt tacaatgaac agaggcatat catttgtagg atgcttagtg
      301 caattctttt ttttctgtac tttcgtggta actgaatctt ttctattagg agtgatggct
      361 tatgacaggt ttgtggccat ccgcaaccct ctactctaca cagtggccat gtcccagagg
      421 ctctgtgcca tgctggtatt gggatcctat gcttgggggg tggtatgctc cttgatactg
      481 acctgctctg ccttgaatct ttctttttat ggtttcaata tgatcaacca ctttttttgt
      541 gagttctcct ctctcctttc actttcacgc tctgacacat ctgtcagtca actgttgctt
      601 ttcgtttttg ccacttttaa tgagattagc acactcctta tcattctctt gtcttatgtg
      661 ctcattgttg ttactattct gaagatgaag tcagcaagtg gacgccgcaa agccttctcc
      721 acttgtgctt cccatctgac agctataacc atcttccatg gaacaatcct attcctatac
      781 tgtgtaccta actccaagaa ctccaggcat accgtaaaag tggcctctgt gttttacaca
      841 gtggtgatcc ccatgctgaa tcccctaata tacagtctga gaaataagga tgtcaaggac
      901 acagtaaaaa aaataatagg tactaaagtc tattcttctt aa
//
