LOCUS       NP_001020557             316 aa            linear   ROD 26-OCT-2024
DEFINITION  olfactory receptor family 52 subfamily A member 20 [Mus musculus].
ACCESSION   NP_001020557 XP_488068
VERSION     NP_001020557.1
DBSOURCE    REFSEQ: accession NM_001025386.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 316)
  AUTHORS   Olender,T., Jones,T.E.M., Bruford,E. and Lancet,D.
  TITLE     A unified nomenclature for vertebrate olfactory receptors
  JOURNAL   BMC Evol Biol 20 (1), 42 (2020)
   PUBMED   32295537
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 316)
  AUTHORS   Zhang,X., Rodriguez,I., Mombaerts,P. and Firestein,S.
  TITLE     Odorant and vomeronasal receptor genes in two mouse genome
            assemblies
  JOURNAL   Genomics 83 (5), 802-811 (2004)
   PUBMED   15081110
REFERENCE   3  (residues 1 to 316)
  AUTHORS   Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
            Walker,M., Williams,E.M. and Trask,B.J.
  TITLE     Odorant receptor expressed sequence tags demonstrate olfactory
            expression of over 400 genes, extensive alternate splicing and
            unequal expression levels
  JOURNAL   Genome Biol 4 (11), R71 (2003)
   PUBMED   14611657
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC143329.3.
            
            On Jul 15, 2005 this sequence version replaced XP_488068.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Mus musculus"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 54.85 cM"
     Protein         1..316
                     /product="olfactory receptor family 52 subfamily A member
                     20"
                     /note="olfactory receptor 243, pseudogene 1; olfactory
                     receptor 627; GA_x6K02T2PBJ9-6440320-6440766;
                     GA_x6K02T2L9TJ-1933-2295"
                     /calculated_mol_wt=36125
     Region          27..302
                     /region_name="7tmA_OR52A-like"
                     /note="olfactory receptor subfamily 52A and related
                     proteins, member of the class A family of
                     seven-transmembrane G protein-coupled receptors; cd15955"
                     /db_xref="CDD:320621"
     Region          28..54
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:320621"
     Region          61..87
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:320621"
     Site            order(83,86..87,99..104,106..107,110,155,157..161,198,
                     201..203,205..207,209..210,255,258..259,261..262,265,
                     273..274,276..278,281,284..285)
                     /site_type="other"
                     /note="putative ligand binding pocket [chemical binding]"
                     /db_xref="CDD:320621"
     Region          99..129
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:320621"
     Region          142..163
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:320621"
     Region          198..228
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:320621"
     Region          235..265
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:320621"
     Region          274..299
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:320621"
     CDS             1..316
                     /gene="Or52a20"
                     /gene_synonym="MOR22-4; Olfr243; Olfr243-ps1; Olfr627;
                     Olfr627-ps1"
                     /coded_by="NM_001025386.1:1..951"
                     /db_xref="CCDS:CCDS21586.1"
                     /db_xref="GeneID:436002"
                     /db_xref="MGI:MGI:3030077"
ORIGIN      
        1 mphlnstifr psvltltgip glesvqfwig ipfcimyiia llgnslllvv ikverslhep
       61 mylflamlga tdiaistcil pkmlgifwfh lptiyfdvcl lqmwlihtfq ciesgilfam
      121 amdryvaicd plrhasiftq rlltqigvgv tlraalfvap clilikcrlk fywttvvshs
      181 ycehmaivkl aaedvhvnki yglfvafsil gldiifitls yirifitvfk lpqkearlka
      241 fntciahicv flefyllaff sffthrfgyh vpsyihills nlyllvppll npivygvktk
      301 qirdqvskil ycnysy
//
