LOCUS       NM_147093               2923 bp    mRNA    linear   ROD 24-OCT-2024
DEFINITION  Mus musculus olfactory receptor family 51 subfamily E member 1
            (Or51e1), mRNA.
ACCESSION   NM_147093
VERSION     NM_147093.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2923)
  AUTHORS   Xu,J., Choi,R., Gupta,K., Warren,H.R., Santhanam,L. and
            Pluznick,J.L.
  TITLE     An evolutionarily conserved olfactory receptor is required for sex
            differences in blood pressure
  JOURNAL   Sci Adv 10 (12), eadk1487 (2024)
   PUBMED   38507492
REFERENCE   2  (bases 1 to 2923)
  AUTHORS   Xu,J. and Pluznick,J.L.
  TITLE     Key amino acids alter activity and trafficking of a well-conserved
            olfactory receptor
  JOURNAL   Am J Physiol Cell Physiol 322 (6), C1279-C1288 (2022)
   PUBMED   35544696
  REMARK    GeneRIF: Key amino acids alter activity and trafficking of a
            well-conserved olfactory receptor.
REFERENCE   3  (bases 1 to 2923)
  AUTHORS   Olender,T., Jones,T.E.M., Bruford,E. and Lancet,D.
  TITLE     A unified nomenclature for vertebrate olfactory receptors
  JOURNAL   BMC Evol Biol 20 (1), 42 (2020)
   PUBMED   32295537
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2923)
  AUTHORS   Chang,A.J., Ortega,F.E., Riegler,J., Madison,D.V. and Krasnow,M.A.
  TITLE     Oxygen regulation of breathing through an olfactory receptor
            activated by lactate
  JOURNAL   Nature 527 (7577), 240-244 (2015)
   PUBMED   26560302
REFERENCE   5  (bases 1 to 2923)
  AUTHORS   Kang,N., Kim,H., Jae,Y., Lee,N., Ku,C.R., Margolis,F., Lee,E.J.,
            Bahk,Y.Y., Kim,M.S. and Koo,J.
  TITLE     Olfactory marker protein expression is an indicator of olfactory
            receptor-associated events in non-olfactory tissues
  JOURNAL   PLoS One 10 (1), e0116097 (2015)
   PUBMED   25635859
  REMARK    GeneRIF: Three olfactory receptors (olfr544, olfr558, and olfr1386)
            were expressed in the olfactory marker protein (+) cells of the
            bladder and thyroid.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2923)
  AUTHORS   Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
            Walker,M., Williams,E.M. and Trask,B.J.
  TITLE     Odorant receptor expressed sequence tags demonstrate olfactory
            expression of over 400 genes, extensive alternate splicing and
            unequal expression levels
  JOURNAL   Genome Biol 4 (11), R71 (2003)
   PUBMED   14611657
REFERENCE   7  (bases 1 to 2923)
  AUTHORS   Young,J.M., Friedman,C., Williams,E.M., Ross,J.A., Tonnes-Priddy,L.
            and Trask,B.J.
  TITLE     Different evolutionary processes shaped the mouse and human
            olfactory receptor gene families
  JOURNAL   Hum Mol Genet 11 (5), 535-546 (2002)
   PUBMED   11875048
  REMARK    Erratum:[Hum Mol Genet. 2002 Jul 1;11(14):1683.]
REFERENCE   8  (bases 1 to 2923)
  AUTHORS   Zhang,X. and Firestein,S.
  TITLE     The olfactory receptor gene superfamily of the mouse
  JOURNAL   Nat Neurosci 5 (2), 124-133 (2002)
   PUBMED   11802173
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK141545.1.
            
            On Apr 6, 2007 this sequence version replaced NM_147093.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK141545.1, BB653241.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2923              AK141545.1         1-2923
FEATURES             Location/Qualifiers
     source          1..2923
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 54.81 cM"
     gene            1..2923
                     /gene="Or51e1"
                     /gene_synonym="MOR18-1; Olfr558; POGR"
                     /note="olfactory receptor family 51 subfamily E member 1"
                     /db_xref="GeneID:259097"
                     /db_xref="MGI:MGI:3030392"
     exon            1..87
                     /gene="Or51e1"
                     /gene_synonym="MOR18-1; Olfr558; POGR"
                     /inference="alignment:Splign:2.1.0"
     exon            88..2923
                     /gene="Or51e1"
                     /gene_synonym="MOR18-1; Olfr558; POGR"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..1083
                     /gene="Or51e1"
                     /gene_synonym="MOR18-1; Olfr558; POGR"
                     /note="olfactory receptor MOR18-1; prostate overexpressed
                     G protein coupled receptor;
                     GA_x6K02T2PBJ9-5425951-5426904; olfactory receptor 558"
                     /codon_start=1
                     /product="olfactory receptor family 51 subfamily E member
                     1"
                     /protein_id="NP_667304.1"
                     /db_xref="CCDS:CCDS21543.1"
                     /db_xref="GeneID:259097"
                     /db_xref="MGI:MGI:3030392"
                     /translation="MVGFNSNESSATYFILIGLPGLEEVQFWLAFPLCSLYLIAVLGN
                     LTIIYIVRTEHSLHEPMYIFLCMLSGLDILISTSSMPKMMAIFWFNSTTIQFDACLVQ
                     MFAIHSLSGMESTVLLAMAFDRYVAICHPLRHATVLTLPRVAKIGMAAVVRGAVLMAP
                     LPVFIKRLPFCRSNILSHSYCLHQDVMKLACADIRVNIIYGLIVIISAIGLDSLLISF
                     SYLLILKTVLGLTREAQAKAFGTCVSHVCAVFIFYVPFIGLSMVHRFSKRRDSLLPVI
                     MANIYLLVPPVLNPIVYGVKTKEIRQRILRLFLVTTHTSDH"
     regulatory      2899..2904
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Or51e1"
                     /gene_synonym="MOR18-1; Olfr558; POGR"
                     /note="putative"
ORIGIN      
        1 ggctttttgc agcctgccag acctccctca ggaaggagga aaaggcactg ggggaaaaga
       61 cacacaggct ctttcaggac agctgagctt cagtcttcct ggtactggct acatcctgat
      121 tccttcagta tggtgggctt caatagcaat gaatccagtg ccacatattt catcttaata
      181 ggccttccag gattggaaga ggttcagttt tggctggctt tccctttgtg ttccctctac
      241 cttattgctg tgctaggtaa cttgacaatc atctacattg tgaggacaga gcacagcctg
      301 catgagccca tgtatatctt tctttgcatg ctttctggcc tagacatcct catttccacc
      361 tcatccatgc caaaaatgat ggccatcttt tggttcaatt ccactaccat ccagtttgat
      421 gcttgtctgg tacagatgtt tgccatccat tccttgtctg gcatggagtc cacagtgctg
      481 ctggccatgg cctttgaccg ctatgtggcc atttgccatc ctctacggca tgccactgtg
      541 ctgacattgc ctcgtgttgc caagattggc atggctgctg tggtcagggg tgcagtacta
      601 atggcaccct tacctgtctt catcaaaagg ttgcctttct gtcgttccaa catcctttct
      661 cattcctact gcctacacca agatgtcatg aagctggcct gtgctgacat ccgtgtcaat
      721 atcatttatg gactcattgt catcatctca gccattggtt tggactcact tctcatttcc
      781 ttctcatatt tgctcatcct caagactgtg ttgggcttga cacgtgaagc ccaggcaaaa
      841 gcgtttggca cttgtgtttc acatgtgtgt gctgttttca tcttctatgt gcctttcatt
      901 ggattgtcga tggtgcaccg tttcagcaag aggcgtgact ctctcctgcc tgtcattatg
      961 gctaacatct atctgctagt tcctcctgtg ctcaacccca ttgtctatgg agtaaagaca
     1021 aaggagatcc ggcagcgcat tcttcgtctt ttcctcgtga ccacacacac ttcagatcac
     1081 taggaaatca tgatgaaacc ttcctccatt caaagttctg taactcacac tttagtatga
     1141 tatcttggaa gacagtatta agaaaataaa tcttaataaa aatatagctc agatctttca
     1201 aggatgaaac ttgctgtgga aattctacgt ggaatggaag aacacctgca atctccattt
     1261 tctaatatta cattcattct tttgtttttt tctctagata attattaaga tcaagacttg
     1321 tgttttgaaa gttatttctc acaattttat cactacttcc aaatttcaat tcatttcact
     1381 gatgatcgtt cacagcattt ggagatggag caacacatcc aaaatgttca tcaaaggcat
     1441 aacaaaagaa aaataaacac aaaactataa taaaatgata ttatctaatt taaaacctca
     1501 tttcctcatc agaattcaca atgactttgg atttctgaga agttagaatt ggattcctta
     1561 ttcaaaacaa tctccaaaga aatattggtt ttcttctggg tcccaggttg gaacaaatac
     1621 acttgcctac attgtgagat gacacacatt gttatgacgg ttgtcatagc catgaagaca
     1681 cttttactta tttaagttta tcaacttttt attggtatcc tgattgcacc aatgtggaaa
     1741 ttgatatttc atgggaaatc agtgaattat attcgactac agaagcttaa aaataggaga
     1801 aaaaaaaaga ggatttttca tgttgaatcc tatgctatgt agaattgtta gacagactgg
     1861 cagaatgctg agttgtgaat ttccagaatc ttacactgtt tttgaagaag gcatttggtc
     1921 atttatttcc acctacctaa tgctgttttg agtaattttc tatcagtaga actcatggct
     1981 ttaatcattc aataaacatt gctcctgcct agcttaatca ttacagtgtc tgcacaatgg
     2041 aaactggagt gttcccaagt aggtttattt gagaaacagt gtggtttctg tggaaaagct
     2101 gcagattccg tgggtatctg aggtgtgact taggagaagc atttgagaat atccaggagc
     2161 ttgttgtata aagagagggc tagtcaccag agtagagagt caaaaggaag agacaagaga
     2221 ctgagtaggc taaatgagac tgaccaggaa gtaagactag ggaaaaggtg ggtccataca
     2281 aaatgaggag cacacacaca agcaagaacc acagataccc agagccttaa gctatgctgc
     2341 aatgagggaa ataatgactg cattcctgcc tgatgtactt accatgaata tagctgagag
     2401 tcctacctag gaatcctatt atctagccac ggcatttaca ggagtgggcg gggcattgta
     2461 ggagcatagt agaagtagat tgttcgggga ttggaattat catccactga aaagtcatat
     2521 tcagatccag ggtgtggctg gtgagtatga gaggcaggca gcaaagaggg ggcagggttg
     2581 aatttcttgt acatggccgg cacagagacc cacttgcata ttcaacttct tggactatac
     2641 tccagaatat aagaactgtg tgtatgataa aattgactag gccaaggtga gggtggccaa
     2701 aggaaatagt atgaaatgta ctcaatgcaa gattgggtca ctttgaactg aggagaggag
     2761 ggtggatagt cattcattgc ccaggagtgc tctgacatcg cagttgagag aaagacatgc
     2821 tcttatttgc aaagtgaaat gtgatcactg taatcaaaaa tcacagatat tctgaaaatg
     2881 taaaagaagt taaaacataa taaagatctt tattctgtta atc
//
