LOCUS       NP_001011754             354 aa            linear   ROD 26-OCT-2024
DEFINITION  olfactory receptor 735 [Mus musculus].
ACCESSION   NP_001011754
VERSION     NP_001011754.1
DBSOURCE    REFSEQ: accession NM_001011754.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 354)
  AUTHORS   Olender,T., Jones,T.E.M., Bruford,E. and Lancet,D.
  TITLE     A unified nomenclature for vertebrate olfactory receptors
  JOURNAL   BMC Evol Biol 20 (1), 42 (2020)
   PUBMED   32295537
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 354)
  AUTHORS   Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
            Walker,M., Williams,E.M. and Trask,B.J.
  TITLE     Odorant receptor expressed sequence tags demonstrate olfactory
            expression of over 400 genes, extensive alternate splicing and
            unequal expression levels
  JOURNAL   Genome Biol 4 (11), R71 (2003)
   PUBMED   14611657
REFERENCE   3  (residues 1 to 354)
  AUTHORS   Young,J.M., Friedman,C., Williams,E.M., Ross,J.A., Tonnes-Priddy,L.
            and Trask,B.J.
  TITLE     Different evolutionary processes shaped the mouse and human
            olfactory receptor gene families
  JOURNAL   Hum Mol Genet 11 (5), 535-546 (2002)
   PUBMED   11875048
  REMARK    Erratum:[Hum Mol Genet. 2002 Jul 1;11(14):1683.]
REFERENCE   4  (residues 1 to 354)
  AUTHORS   Zhang,X. and Firestein,S.
  TITLE     The olfactory receptor gene superfamily of the mouse
  JOURNAL   Nat Neurosci 5 (2), 124-133 (2002)
   PUBMED   11802173
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC135188.2.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 26.06 cM"
     Protein         1..354
                     /product="olfactory receptor 735"
                     /note="olfactory receptor MOR243-1;
                     GA_x6K02T2PMLR-6042130-6041183"
                     /calculated_mol_wt=40090
     Region          76..331
                     /region_name="7tmA_OR4-like"
                     /note="olfactory receptor family 4 and related proteins,
                     member of the class A family of seven-transmembrane G
                     protein-coupled receptors; cd15226"
                     /db_xref="CDD:320354"
     Region          99..125
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:320354"
     Site            order(121,124..125,137..142,144..145,148,193,195..199,235,
                     238..240,242..244,246..247,291,294..295,297..298,301,
                     305..306,308..310,313,316..317)
                     /site_type="other"
                     /note="putative ligand binding pocket [chemical binding]"
                     /db_xref="CDD:320354"
     Region          137..167
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:320354"
     Region          180..201
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:320354"
     Region          235..265
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:320354"
     Region          271..301
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:320354"
     Region          306..331
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:320354"
     CDS             1..354
                     /gene="Or4q3"
                     /gene_synonym="MOR243-1; Olfr735"
                     /coded_by="NM_001011754.2:1..1065"
                     /db_xref="CCDS:CCDS27011.1"
                     /db_xref="GeneID:257909"
                     /db_xref="MGI:MGI:3030569"
ORIGIN      
        1 mvhadkqevl shnfsflfnl tylvqfnfss trsldtlgle knknssdvsr fvllglsssw
       61 elqlflfftf lliylvivlg nllivmvvqa dahlfqspmy yflshlsfid lclscvavpk
      121 mlgdflqkek tisfsgclaq vfflhflgas emflltvmay dryvaicnpl hyltvmnnhl
      181 rlrlvfgcwc ggfihsitqv miviqlpfcg pneldnfycd vpqvvklacm dtylvevlmv
      241 snsgilslvc flvllfsyal ilitlrthlh rgqskalstc ashltvvsli fvpcvfiylr
      301 pfctfsvdkv vsvfytvitp mlnpliytlr nadmkqaiek lrkkqvashc fakg
//
