LOCUS       NM_001170918            1605 bp    mRNA    linear   ROD 06-NOV-2024
DEFINITION  Mus musculus olfactory receptor family 4 subfamily E member 5
            (Or4e5), transcript variant 1, mRNA.
ACCESSION   NM_001170918
VERSION     NM_001170918.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1605)
  AUTHORS   Raja,R., Dumontier,E., Phen,A. and Cloutier,J.F.
  TITLE     Insertion of a neomycin selection cassette in the Amigo1 locus
            alters gene expression in the olfactory epithelium leading to
            region-specific defects in olfactory receptor neuron development
  JOURNAL   Genesis 62 (2), e23594 (2024)
   PUBMED   38590146
REFERENCE   2  (bases 1 to 1605)
  AUTHORS   Pourmorady,A.D., Bashkirova,E.V., Chiariello,A.M., Belagzhal,H.,
            Kodra,A., Duffie,R., Kahiapo,J., Monahan,K., Pulupa,J.,
            Schieren,I., Osterhoudt,A., Dekker,J., Nicodemi,M. and Lomvardas,S.
  TITLE     RNA-mediated symmetry breaking enables singular olfactory receptor
            choice
  JOURNAL   Nature 625 (7993), 181-188 (2024)
   PUBMED   38123679
REFERENCE   3  (bases 1 to 1605)
  AUTHORS   Martinez,A.P., Chung,A.C., Huang,S., Bisogni,A.J., Lin,Y., Cao,Y.,
            Williams,E.O., Kim,J.Y., Yang,J.Y.H. and Lin,D.M.
  TITLE     Pcdh19 mediates olfactory sensory neuron coalescence during
            postnatal stages and regeneration
  JOURNAL   iScience 26 (11), 108220 (2023)
   PUBMED   37965156
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1605)
  AUTHORS   Causeret,F., Fayon,M., Moreau,M.X., Ne,E., Oleari,R., Parras,C.,
            Cariboni,A. and Pierani,A.
  TITLE     Diversity within olfactory sensory derivatives revealed by the
            contribution of Dbx1 lineages
  JOURNAL   J Comp Neurol 531 (12), 1229-1243 (2023)
   PUBMED   37125418
REFERENCE   5  (bases 1 to 1605)
  AUTHORS   Shayya,H.J., Kahiapo,J.K., Duffie,R., Lehmann,K.S., Bashkirova,L.,
            Monahan,K., Dalton,R.P., Gao,J., Jiao,S., Schieren,I., Belluscio,L.
            and Lomvardas,S.
  TITLE     ER stress transforms random olfactory receptor choice into axon
            targeting precision
  JOURNAL   Cell 185 (21), 3896-3912 (2022)
   PUBMED   36167070
REFERENCE   6  (bases 1 to 1605)
  AUTHORS   Zhang,X. and Firestein,S.
  TITLE     The olfactory receptor gene superfamily of the mouse
  JOURNAL   Nat Neurosci 5 (2), 124-133 (2002)
   PUBMED   11802173
REFERENCE   7  (bases 1 to 1605)
  AUTHORS   Ishii,T., Serizawa,S., Kohda,A., Nakatani,H., Shiroishi,T.,
            Okumura,K., Iwakura,Y., Nagawa,F., Tsuboi,A. and Sakano,H.
  TITLE     Monoallelic expression of the odourant receptor gene and axonal
            projection of olfactory sensory neurones
  JOURNAL   Genes Cells 6 (1), 71-78 (2001)
   PUBMED   11277098
  REMARK    Erratum:[Genes Cells 2001 Jun;6(6):573]
REFERENCE   8  (bases 1 to 1605)
  AUTHORS   Serizawa,S., Ishii,T., Nakatani,H., Tsuboi,A., Nagawa,F., Asano,M.,
            Sudo,K., Sakagami,J., Sakano,H., Ijiri,T., Matsuda,Y., Suzuki,M.,
            Yamamori,T., Iwakura,Y. and Sakano,H.
  TITLE     Mutually exclusive expression of odorant receptor transgenes
  JOURNAL   Nat Neurosci 3 (7), 687-693 (2000)
   PUBMED   10862701
REFERENCE   9  (bases 1 to 1605)
  AUTHORS   Tsuboi,A., Yoshihara,S., Yamazaki,N., Kasai,H., Asai-Tsuboi,H.,
            Komatsu,M., Serizawa,S., Ishii,T., Matsuda,Y., Nagawa,F. and
            Sakano,H.
  TITLE     Olfactory neurons expressing closely linked and homologous odorant
            receptor genes tend to project their axons to neighboring glomeruli
            on the olfactory bulb
  JOURNAL   J Neurosci 19 (19), 8409-8418 (1999)
   PUBMED   10493742
REFERENCE   10 (bases 1 to 1605)
  AUTHORS   Sullivan,S.L., Adamson,M.C., Ressler,K.J., Kozak,C.A. and Buck,L.B.
  TITLE     The chromosomal distribution of mouse odorant receptor genes
  JOURNAL   Proc Natl Acad Sci U S A 93 (2), 884-888 (1996)
   PUBMED   8570653
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB173597.1, CB174012.1 and BC119165.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB174276.1, CB173276.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 CB173597.1         1-4
            5-578               CB174012.1         1-574
            579-1605            BC119165.1         86-1112
FEATURES             Location/Qualifiers
     source          1..1605
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 26.97 cM"
     gene            1..1605
                     /gene="Or4e5"
                     /gene_synonym="MOR244-1; Mor28; Olfr1507; Or28"
                     /note="olfactory receptor family 4 subfamily E member 5"
                     /db_xref="GeneID:57269"
                     /db_xref="MGI:MGI:3031341"
     exon            1..567
                     /gene="Or4e5"
                     /gene_synonym="MOR244-1; Mor28; Olfr1507; Or28"
                     /inference="alignment:Splign:2.1.0"
     exon            568..1605
                     /gene="Or4e5"
                     /gene_synonym="MOR244-1; Mor28; Olfr1507; Or28"
                     /inference="alignment:Splign:2.1.0"
     CDS             578..1519
                     /gene="Or4e5"
                     /gene_synonym="MOR244-1; Mor28; Olfr1507; Or28"
                     /note="gene for odorant receptor MOR28; olfactory receptor
                     MOR244-1; GA_x6K02T2RJGY-491851-492792"
                     /codon_start=1
                     /product="olfactory receptor 1507"
                     /protein_id="NP_001164389.1"
                     /db_xref="CCDS:CCDS27062.1"
                     /db_xref="GeneID:57269"
                     /db_xref="MGI:MGI:3031341"
                     /translation="MEKAVLINQTSVMSFRLTGLSTNPKVQMAIFFIFLIFYVLTLVG
                     NILIVITIIHDHRLHTPMYFFLSNLSFIDVCHSTVTVPKMLSDTFSEEKLISFDDCVV
                     QIFFLHLFACTEIFLLTVMAYDRYVAICKPLRYMTIMNWKVCMVLGGAMWTAGTIHSI
                     SFTSLTIKLPYCGPNELDSFFCDVPQVIELACTDTRITEILVVSNSGMISMVCFVIIV
                     VSYAVILVSLRQQISDGKRKALSTCAAHLTVVTLFLGHCIFIYSRPAISLPEDKIVSA
                     FFTAITPLLNPIIYTFRNEDMKSALKKLIRRKEGKEK"
ORIGIN      
        1 cagccacagc tgtttgcttg ctttatgatt ccccttcaga gtttaagaga tgaatgtcgc
       61 atctggaact aatgatagaa cttgcaccta aagtgtgcaa caagaccctt cagccacact
      121 ggggttctga gtaagtcggt gaccagacaa ttttgttttt aaattgtcct gacaaactgg
      181 tacagctctg aaactggttg ctcacagcgt ggaatccctc ctcatcgctg ggtctgaaaa
      241 gacacagaag atacactgtc cttgtcgcac aacttcagtc tgctgaacac catcctagaa
      301 attcttgctg cagagttatt tgcatagtga gacaagggca aaaagtatag atgcaaaggg
      361 ttggtttgct caggaatctg gaatagtgcc tctctgccct gacacgacaa gcaggctctc
      421 caggactaca gtaacacgag atgttctgac tacccaactt gaagaaagtt gtttctttta
      481 ctggaagata attttcgttg tattcaaact accagacaga atacccaagt atctttgaag
      541 ggactgagag aatcagaaag aattcagaac taaaagaatg gaaaaggctg tcctcatcaa
      601 ccaaacttca gtgatgtcat ttcggctcac aggtttatct acaaatccga aagtacagat
      661 ggctattttt ttcatattcc tcattttcta tgtcctgaca ctggttggta acatcctcat
      721 tgtcataaca atcatacacg accaccgact ccatactccc atgtatttct tcctcagcaa
      781 tctgtccttt attgatgtct gccattccac tgtcactgtc ccaaagatgc taagtgacac
      841 cttctcagaa gaaaagctca tttcctttga tgactgtgtg gtccagatat ttttcctgca
      901 tctctttgcc tgcacagaga tcttccttct tactgtcatg gcctatgatc gctatgtggc
      961 catttgtaaa cctttgaggt atatgacaat aatgaactgg aaggtgtgta tggtgctagg
     1021 aggggccatg tggacagcag ggaccataca ctccatatct ttcacctcac tcaccatcaa
     1081 gctgccctac tgtggtccta atgagcttga cagcttcttc tgtgatgtac ctcaggtgat
     1141 cgaactggcc tgcactgaca cccgtatcac tgagattctc gttgtctcca acagtgggat
     1201 gatctctatg gtatgttttg tgattattgt agtgtcctat gcagtcatcc ttgtgagtct
     1261 gaggcaacag atctctgacg gcaagaggaa agccttgtcc acctgtgcag cccatctcac
     1321 cgtagtcact ctgtttctgg gacactgtat cttcatctac tcacgcccag ccatcagcct
     1381 tccagaggac aagattgtat ctgcattttt cacggccata acccctctgc tgaaccccat
     1441 aatctacacc tttaggaatg aggacatgaa gagtgccttg aagaagttaa tcaggagaaa
     1501 agaggggaaa gaaaagtgaa aatgataagt gcttaggatt cttggtaatc taaatcaaag
     1561 aagcaactat atattgtatt taacagatga catgacaaca tttca
//
