LOCUS       NM_146744                985 bp    mRNA    linear   ROD 26-OCT-2024
DEFINITION  Mus musculus olfactory receptor family 2 subfamily W member 4
            (Or2w4), mRNA.
ACCESSION   NM_146744
VERSION     NM_146744.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 985)
  AUTHORS   Olender,T., Jones,T.E.M., Bruford,E. and Lancet,D.
  TITLE     A unified nomenclature for vertebrate olfactory receptors
  JOURNAL   BMC Evol Biol 20 (1), 42 (2020)
   PUBMED   32295537
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 985)
  AUTHORS   Yu,Y., de March,C.A., Ni,M.J., Adipietro,K.A., Golebiowski,J.,
            Matsunami,H. and Ma,M.
  TITLE     Responsiveness of G protein-coupled odorant receptors is partially
            attributed to the activation mechanism
  JOURNAL   Proc Natl Acad Sci U S A 112 (48), 14966-14971 (2015)
   PUBMED   26627247
  REMARK    GeneRIF: a single mutation in MOR256-8 was sufficient to confer
            both high basal activity and broad responsiveness to this receptor.
REFERENCE   3  (bases 1 to 985)
  AUTHORS   Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
            Walker,M., Williams,E.M. and Trask,B.J.
  TITLE     Odorant receptor expressed sequence tags demonstrate olfactory
            expression of over 400 genes, extensive alternate splicing and
            unequal expression levels
  JOURNAL   Genome Biol 4 (11), R71 (2003)
   PUBMED   14611657
REFERENCE   4  (bases 1 to 985)
  AUTHORS   Young,J.M., Friedman,C., Williams,E.M., Ross,J.A., Tonnes-Priddy,L.
            and Trask,B.J.
  TITLE     Different evolutionary processes shaped the mouse and human
            olfactory receptor gene families
  JOURNAL   Hum Mol Genet 11 (5), 535-546 (2002)
   PUBMED   11875048
  REMARK    Erratum:[Hum Mol Genet. 2002 Jul 1;11(14):1683.]
REFERENCE   5  (bases 1 to 985)
  AUTHORS   Zhang,X. and Firestein,S.
  TITLE     The olfactory receptor gene superfamily of the mouse
  JOURNAL   Nat Neurosci 5 (2), 124-133 (2002)
   PUBMED   11802173
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC119336.1 and AL589651.8.
            
            On Oct 30, 2011 this sequence version replaced NM_146744.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC119338.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-330               BC119336.1         1-330
            331-949             AL589651.8         32046-32664         c
            950-985             BC119336.1         950-985
FEATURES             Location/Qualifiers
     source          1..985
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 7.88 cM"
     gene            1..985
                     /gene="Or2w4"
                     /gene_synonym="MOR256-8; Olfr1362; Olfr1363-ps1"
                     /note="olfactory receptor family 2 subfamily W member 4"
                     /db_xref="GeneID:258739"
                     /db_xref="MGI:MGI:3031196"
     exon            1..985
                     /gene="Or2w4"
                     /gene_synonym="MOR256-8; Olfr1362; Olfr1363-ps1"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..964
                     /gene="Or2w4"
                     /gene_synonym="MOR256-8; Olfr1362; Olfr1363-ps1"
                     /note="olfactory receptor MOR256-8;
                     GA_x6K02T2QHY8-11617756-11618682; olfactory receptor 1363,
                     pseudogene 1; GA_x6K02T2QHY8-11628399-11628868"
                     /codon_start=1
                     /product="olfactory receptor 1362"
                     /protein_id="NP_666955.2"
                     /db_xref="CCDS:CCDS26282.1"
                     /db_xref="GeneID:258739"
                     /db_xref="MGI:MGI:3031196"
                     /translation="MEKSNDSSEYGFILEGFSDRPRLEMVLFIVNFTLYSVAVLGNIT
                     IILVCILDPRLHTPMYFFLANLSFLDLCFSTSCIPQMLVNLWGPDKTISYAGCVVQLF
                     SFLSIGSVECILLAVMAYDRYAAVCKPLHYMVIMHPQLCVRLMAVAWGVGLANAIIMS
                     PLAMTLPRCGRRRINHFLCELPALIKMACVDARPVEMLSFTLAILIVLLPLTLILVSY
                     GYIAAAVLRIKSAAGRWKAFNTCSSHLTVVSLFYGSIIYMYMQPGNSSSQDQGKFLTL
                     FYNLVTPMLNPLIYTLRNKEMKGALKKVCGRH"
ORIGIN      
        1 cccagctgca cagagctgat gatgtgaaag aaagtcaatg gagaagtcca acgacagctc
       61 tgagtatggt ttcatcttag aaggcttctc tgatcgccct cgcctggaga tggtactctt
      121 catagtaaat tttactctgt attcggtggc tgtgctggga aatataacca ttatcctggt
      181 gtgtatattg gaccctcggc ttcacactcc aatgtacttc tttctggcaa atctttcatt
      241 tctggatctc tgcttcagta ccagctgcat cccacagatg ctggtaaacc tctggggccc
      301 agacaagacc atcagctatg ctggctgtgt ggtccaactt ttctccttcc tgtcgattgg
      361 cagtgtagag tgcatccttc tggctgtcat ggcttatgac cgctatgctg ccgtctgcaa
      421 acctttgcac tatatggtca ttatgcaccc acagctgtgt gtgaggctga tggctgtggc
      481 ctggggggtt ggactcgcca atgccatcat catgtcacca ctagcaatga ccctgcccag
      541 atgtggccgc cggagaatta atcatttcct ttgtgaactg ccagctctga tcaagatggc
      601 ctgtgtggat gctcgcccgg tggaaatgtt gtccttcact ttggccatcc ttattgtcct
      661 gctacccctc actctgatcc ttgtctccta tggttacatt gctgcagctg tgctgaggat
      721 caagtcggct gctgggagat ggaaagcctt caacacctgc agctcccacc tcactgtggt
      781 ctccctgttc tatggaagta tcatttatat gtatatgcag cctggaaaca gctcttccca
      841 ggaccaaggg aaatttctca ctctcttcta taacttggtg actcccatgc tgaatccact
      901 catctatact ttacggaaca aggaaatgaa aggggcactg aaaaaggttt gtgggaggca
      961 ctgagggaca gaagcaaaca atggg
//
