LOCUS       NM_001172686            1210 bp    mRNA    linear   ROD 26-OCT-2024
DEFINITION  Mus musculus olfactory receptor family 1 subfamily E member 1C
            (Or1e1c), transcript variant 1, mRNA.
ACCESSION   NM_001172686
VERSION     NM_001172686.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1210)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1210)
  AUTHORS   Olender,T., Jones,T.E.M., Bruford,E. and Lancet,D.
  TITLE     A unified nomenclature for vertebrate olfactory receptors
  JOURNAL   BMC Evol Biol 20 (1), 42 (2020)
   PUBMED   32295537
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1210)
  AUTHORS   Fleischer,J., Schwarzenbacher,K., Besser,S., Hass,N. and Breer,H.
  TITLE     Olfactory receptors and signalling elements in the Grueneberg
            ganglion
  JOURNAL   J Neurochem 98 (2), 543-554 (2006)
   PUBMED   16805845
REFERENCE   4  (bases 1 to 1210)
  AUTHORS   Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
            Walker,M., Williams,E.M. and Trask,B.J.
  TITLE     Odorant receptor expressed sequence tags demonstrate olfactory
            expression of over 400 genes, extensive alternate splicing and
            unequal expression levels
  JOURNAL   Genome Biol 4 (11), R71 (2003)
   PUBMED   14611657
REFERENCE   5  (bases 1 to 1210)
  AUTHORS   Young,J.M., Friedman,C., Williams,E.M., Ross,J.A., Tonnes-Priddy,L.
            and Trask,B.J.
  TITLE     Different evolutionary processes shaped the mouse and human
            olfactory receptor gene families
  JOURNAL   Hum Mol Genet 11 (5), 535-546 (2002)
   PUBMED   11875048
  REMARK    Erratum:[Hum Mol Genet. 2002 Jul 1;11(14):1683.]
REFERENCE   6  (bases 1 to 1210)
  AUTHORS   Zhang,X. and Firestein,S.
  TITLE     The olfactory receptor gene superfamily of the mouse
  JOURNAL   Nat Neurosci 5 (2), 124-133 (2002)
   PUBMED   11802173
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645739.9.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and it encodes the longer isoform (1). The coding region
            contains an intron, which is atypical for olfactory receptor genes,
            so translation initiation may actually occur at a downstream
            in-frame start codon.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DR065550.1, DR065641.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-125               AL645739.9         104335-104459
            126-256             AL645739.9         105022-105152
            257-1210            AL645739.9         107840-108793
FEATURES             Location/Qualifiers
     source          1..1210
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 45.32 cM"
     gene            1..1210
                     /gene="Or1e1c"
                     /gene_synonym="MOR135-12; Olfr376"
                     /note="olfactory receptor family 1 subfamily E member 1C"
                     /db_xref="GeneID:258924"
                     /db_xref="MGI:MGI:3030210"
     exon            1..125
                     /gene="Or1e1c"
                     /gene_synonym="MOR135-12; Olfr376"
                     /inference="alignment:Splign:2.1.0"
     exon            126..256
                     /gene="Or1e1c"
                     /gene_synonym="MOR135-12; Olfr376"
                     /inference="alignment:Splign:2.1.0"
     CDS             248..1210
                     /gene="Or1e1c"
                     /gene_synonym="MOR135-12; Olfr376"
                     /note="isoform 1 is encoded by transcript variant 1;
                     olfactory receptor MOR135-12;
                     GA_x6K02T2P1NL-3535075-3536028; olfactory receptor 376"
                     /codon_start=1
                     /product="olfactory receptor 376 isoform 1"
                     /protein_id="NP_001166157.1"
                     /db_xref="CCDS:CCDS48844.1"
                     /db_xref="GeneID:258924"
                     /db_xref="MGI:MGI:3030210"
                     /translation="MSQMQGTTERNQTAISQFLLLGLPIPTEHQHLFYALFLAMYLTT
                     VLGNLIIIILIHLDSHLHTPMYSFLSNLSFSDLCFSSVTMPKLLQNMQSQDPSIPYAG
                     CLAQMYFFLFFADLESFLLVAMAYDRYVAICFPLHYMSIMSPRLCVSLVLLSWVLTTF
                     HAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLSCSDTYVNELVIFVMGSLILVIPFV
                     LILVSYARIVSSILKVPSARGIRKAFSTCGSHLSVVSLFYGTVIGLYLCPSADNSTVK
                     ETVMAMMYTVVTPMLNPFIYSLRNRDMKGALISVLCKKKILFCL"
     exon            257..1210
                     /gene="Or1e1c"
                     /gene_synonym="MOR135-12; Olfr376"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aatgtgagca ggtgtggtac atacacagat gatggctgtt gagaccatct tttctatgct
       61 tatgatgcat aaatgggagc aggattttag accagggtcc tggagttacc ctgagatatt
      121 tctggtgctg gggactaaac tgaatgtctt gggaatgcta gacaagcatt ctaccaccgg
      181 gctgtacctc cagcttgaag ctctgcagtt tatgactctc atgtgtagcc ttgactgaga
      241 actgcatatg agccagatgc agggcaccac agaaaggaat caaactgcca tctcccagtt
      301 cctcctcctg ggcctgccca tccccacaga gcatcaacac ctgttctatg ccctgttcct
      361 ggccatgtac ctcaccaccg tcctggggaa cctcatcatc atcatcctta ttcatctgga
      421 ctcccatctc cacacaccca tgtattcttt cctcagcaat ttgtccttct ctgatctctg
      481 cttttcatct gtcacaatgc ccaaattgct gcagaacatg cagagccagg atccatcaat
      541 tccctatgca ggctgcctgg cacaaatgta ctttttcctg ttttttgcag accttgaaag
      601 cttcctcctt gtggccatgg cctatgaccg ctatgtggct atctgcttcc cccttcatta
      661 catgagcatc atgagcccca ggctctgtgt gagtctggtg ctgctgtcct gggtgctgac
      721 caccttccat gccatgctgc ataccctgct catggccaga ttgtcattct gtgaggacaa
      781 tgtgatcccc cactttttct gtgacatgtc tgctctgctg aagctgtcct gctctgacac
      841 ctatgttaat gaattggtga tatttgtcat gggaagcctg atccttgtca ttccatttgt
      901 gctcatcctt gtgtcctatg cacgaattgt gtcctccatt ctcaaggtcc cgtctgctcg
      961 aggcatccgt aaagccttct ccacctgtgg gtcccacctg tctgtggtgt cactgttcta
     1021 tggaacagtc attggtctgt acttatgtcc atcagctgat aactctactg tgaaggaaac
     1081 tgtcatggcc atgatgtaca cagtggtgac tcccatgctg aaccccttca tctacagcct
     1141 gaggaacaga gacatgaagg gggccctaat tagtgttctt tgcaagaaga aaattctttt
     1201 ctgtctatga
//
