LOCUS       NM_146711               1092 bp    mRNA    linear   ROD 24-OCT-2024
DEFINITION  Mus musculus olfactory receptor family 1 subfamily A member 1B
            (Or1a1b), mRNA.
ACCESSION   NM_146711
VERSION     NM_146711.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1092)
  AUTHORS   Olender,T., Jones,T.E.M., Bruford,E. and Lancet,D.
  TITLE     A unified nomenclature for vertebrate olfactory receptors
  JOURNAL   BMC Evol Biol 20 (1), 42 (2020)
   PUBMED   32295537
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1092)
  AUTHORS   Wu,C., Thach,T.T., Kim,Y.J. and Lee,S.J.
  TITLE     Olfactory receptor 43 reduces hepatic lipid accumulation and
            adiposity in mice
  JOURNAL   Biochim Biophys Acta Mol Cell Biol Lipids 1864 (4), 489-499 (2019)
   PUBMED   30639733
  REMARK    GeneRIF: Results show that Olfr43 activates the PKA-CREB pathway in
            mouse hepatocytes. It plays a key role in the regulation of hepatic
            steatosis in high fat diet-fed mice.
REFERENCE   3  (bases 1 to 1092)
  AUTHORS   Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
            Walker,M., Williams,E.M. and Trask,B.J.
  TITLE     Odorant receptor expressed sequence tags demonstrate olfactory
            expression of over 400 genes, extensive alternate splicing and
            unequal expression levels
  JOURNAL   Genome Biol 4 (11), R71 (2003)
   PUBMED   14611657
REFERENCE   4  (bases 1 to 1092)
  AUTHORS   Young,J.M., Friedman,C., Williams,E.M., Ross,J.A., Tonnes-Priddy,L.
            and Trask,B.J.
  TITLE     Different evolutionary processes shaped the mouse and human
            olfactory receptor gene families
  JOURNAL   Hum Mol Genet 11 (5), 535-546 (2002)
   PUBMED   11875048
  REMARK    Erratum:[Hum Mol Genet. 2002 Jul 1;11(14):1683.]
REFERENCE   5  (bases 1 to 1092)
  AUTHORS   Zhang,X. and Firestein,S.
  TITLE     The olfactory receptor gene superfamily of the mouse
  JOURNAL   Nat Neurosci 5 (2), 124-133 (2002)
   PUBMED   11802173
REFERENCE   6  (bases 1 to 1092)
  AUTHORS   Lapidot,M., Pilpel,Y., Gilad,Y., Falcovitz,A., Sharon,D., Haaf,T.
            and Lancet,D.
  TITLE     Mouse-human orthology relationships in an olfactory receptor gene
            cluster
  JOURNAL   Genomics 71 (3), 296-306 (2001)
   PUBMED   11170746
REFERENCE   7  (bases 1 to 1092)
  AUTHORS   Krautwurst,D., Yau,K.W. and Reed,R.R.
  TITLE     Identification of ligands for olfactory receptors by functional
            expression of a receptor library
  JOURNAL   Cell 95 (7), 917-926 (1998)
   PUBMED   9875846
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC125464.1 and AL604065.7.
            
            On May 12, 2009 this sequence version replaced NM_146711.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC125468.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-725               BC125464.1         1-725
            726-726             AL604065.7         56932-56932         c
            727-1025            BC125464.1         727-1025
            1026-1026           AL604065.7         56632-56632         c
            1027-1092           BC125464.1         1027-1092
FEATURES             Location/Qualifiers
     source          1..1092
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 45.76 cM"
     gene            1..1092
                     /gene="Or1a1b"
                     /gene_synonym="IA7; MOR125-1; MOR125-5_p; Olfr403; Olfr43"
                     /note="olfactory receptor family 1 subfamily A member 1B"
                     /db_xref="GeneID:258706"
                     /db_xref="MGI:MGI:1333770"
     exon            1..1092
                     /gene="Or1a1b"
                     /gene_synonym="IA7; MOR125-1; MOR125-5_p; Olfr403; Olfr43"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..1017
                     /gene="Or1a1b"
                     /gene_synonym="IA7; MOR125-1; MOR125-5_p; Olfr403; Olfr43"
                     /note="olfactory receptor MOR125-1; olfactory receptor
                     403; GA_x6K02T2P1NL-4359899-4358958"
                     /codon_start=1
                     /product="olfactory receptor 43"
                     /protein_id="NP_666922.2"
                     /db_xref="CCDS:CCDS25028.1"
                     /db_xref="GeneID:258706"
                     /db_xref="MGI:MGI:1333770"
                     /translation="MREENESSTTDFTLLGVTRQREQEYFFFILFLFIYPITVFGNML
                     IILAIHSDTRLHNPMYFFLANLSLVDIFFSSVTIPKMLANHLLGSKAISFGGCMAQMY
                     FMIGLANTDSYILAAMAYDRAVAISRPLHYATIMSPQLCVLLVAGSWVIANANALPHT
                     LLTARLSFCGNKDVANFYCDITPLLQLSCSDIRFNVKMMYLGVGVFSVPLLCIIISYV
                     RVFSTVLRVPSTKGFLKALSTCGSHLTVVSLYYGTVMGMYFRPLTSYSLKHALITVMY
                     TAVTPMLNPFIYSLRNRDMKAALKKLFHCPSSSSSLM"
ORIGIN      
        1 gggggactgg cagcctatag ataataatca cactaatggt tctgggttca tgtctgattt
       61 catgttgaag gagccatgag agaagaaaac gagtcttcta ccacagattt cactctcctg
      121 ggagttacaa ggcagcggga gcaggaatat ttcttcttca tcctcttcct gttcatttac
      181 cccatcacag tgtttgggaa catgctcatc atcctagcca ttcactctga cactcgcctc
      241 cataacccta tgtacttttt cctggccaac ctctcccttg ttgacatctt cttctcctct
      301 gtaactattc ccaagatgct ggccaaccat ctcctaggta gcaaggccat ctcctttggg
      361 ggatgtatgg cacagatgta cttcatgata ggcttggcaa atacagacag ttatatacta
      421 gctgcaatgg catatgaccg agctgtggct atcagtcgcc cacttcatta tgcaacaatt
      481 atgagtccac aactttgtgt cctgctggtt gctgggtcct gggtgattgc aaatgctaat
      541 gcactgcccc acaccctact cacagctaga ctgtccttct gtggcaataa ggatgtggcc
      601 aacttctact gtgacattac acctttgctc cagctgtcct gttctgacat ccgcttcaat
      661 gtgaagatga tgtaccttgg ggtgggggtc ttctctgtgc cactgctgtg catcatcatc
      721 tcctacgtcc gggtcttttc cacagtcttg cgggttccat ctaccaaggg cttcctgaag
      781 gccttgtcca cctgtggctc tcacctgaca gtggtgtcct tgtattatgg gacagtcatg
      841 ggcatgtatt tccggcccct gaccagttac agtctgaagc atgcattgat aactgtgatg
      901 tacacggcag tgaccccaat gctgaaccct ttcatctaca gcctgaggaa ccgggacatg
      961 aaggctgctc tgaagaaact cttccactgc ccctcttcct cttcctccct catgtgagac
     1021 catgcccagc tgatactgtg gtcccaagtc agaagcacta ggaaactcag cttcaatgtc
     1081 acccctgcaa gg
//
