LOCUS       NM_007538               2420 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus opsin 1 (cone pigments), short-wave-sensitive (color
            blindness, tritan) (Opn1sw), mRNA.
ACCESSION   NM_007538
VERSION     NM_007538.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2420)
  AUTHORS   Nord,C., Jones,I., Garcia-Maestre,M., Hagglund,A.C. and Carlsson,L.
  TITLE     Reduced mTORC1-signaling in progenitor cells leads to retinal
            lamination deficits
  JOURNAL   Dev Dyn 253 (10), 922-939 (2024)
   PUBMED   38546215
REFERENCE   2  (bases 1 to 2420)
  AUTHORS   Liu,Y., Ng,L., Liu,H., Heuer,H. and Forrest,D.
  TITLE     Cone photoreceptor differentiation regulated by thyroid hormone
            transporter MCT8 in the retinal pigment epithelium
  JOURNAL   Proc Natl Acad Sci U S A 121 (30), e2402560121 (2024)
   PUBMED   39018199
REFERENCE   3  (bases 1 to 2420)
  AUTHORS   Sechrest,E.R., Ma,X., Cahill,M.E., Barbera,R.J., Wang,Y. and
            Deng,W.T.
  TITLE     Structural and functional rescue of cones carrying the most common
            cone opsin C203R missense mutation
  JOURNAL   JCI Insight 9 (2), e172834 (2024)
   PUBMED   38060327
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2420)
  AUTHORS   Li,Y., Xiao,D., Chen,H., Zheng,X.F.S. and Xiang,M.
  TITLE     Maf1 controls retinal neuron number by both RNA Pol III- and Pol
            II-dependent mechanisms
  JOURNAL   iScience 26 (12), 108544 (2023)
   PUBMED   38089586
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2420)
  AUTHORS   Kuzelova,A., Dupacova,N., Antosova,B., Sunny,S.S., Kozmik,Z. Jr.,
            Paces,J., Skoultchi,A.I., Stopka,T. and Kozmik,Z.
  TITLE     Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell
            Proliferation and Photoreceptor Maintenance
  JOURNAL   Cells 12 (7), 1035 (2023)
   PUBMED   37048108
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2420)
  AUTHORS   Hong,D.H., Pawlyk,B.S., Shang,J., Sandberg,M.A., Berson,E.L. and
            Li,T.
  TITLE     A retinitis pigmentosa GTPase regulator (RPGR)-deficient mouse
            model for X-linked retinitis pigmentosa (RP3)
  JOURNAL   Proc Natl Acad Sci U S A 97 (7), 3649-3654 (2000)
   PUBMED   10725384
REFERENCE   7  (bases 1 to 2420)
  AUTHORS   Hunt,D.M., Cowing,J.A., Patel,R., Appukuttan,B., Bowmaker,J.K. and
            Mollon,J.D.
  TITLE     Sequence and evolution of the blue cone pigment gene in Old and New
            World primates
  JOURNAL   Genomics 27 (3), 535-538 (1995)
   PUBMED   7558038
REFERENCE   8  (bases 1 to 2420)
  AUTHORS   Chiu,M.I. and Nathans,J.
  TITLE     A sequence upstream of the mouse blue visual pigment gene directs
            blue cone-specific transgene expression in mouse retinas
  JOURNAL   Vis Neurosci 11 (4), 773-780 (1994)
   PUBMED   7918227
REFERENCE   9  (bases 1 to 2420)
  AUTHORS   Chiu,M.I., Zack,D.J., Wang,Y. and Nathans,J.
  TITLE     Murine and bovine blue cone pigment genes: cloning and
            characterization of two new members of the S family of visual
            pigments
  JOURNAL   Genomics 21 (2), 440-443 (1994)
   PUBMED   8088841
REFERENCE   10 (bases 1 to 2420)
  AUTHORS   Weitz,C.J., Went,L.N. and Nathans,J.
  TITLE     Human tritanopia associated with a third amino acid substitution in
            the blue-sensitive visual pigment
  JOURNAL   Am J Hum Genet 51 (2), 444-446 (1992)
   PUBMED   1386496
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK620498.1 and BC026021.1.
            
            On Aug 12, 2009 this sequence version replaced NM_007538.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC026021.1, AF190670.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164132, SAMN01164133
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                CK620498.1         1-33
            34-2420             BC026021.1         1-2387
FEATURES             Location/Qualifiers
     source          1..2420
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 12.36 cM"
     gene            1..2420
                     /gene="Opn1sw"
                     /gene_synonym="Bcp"
                     /note="opsin 1 (cone pigments), short-wave-sensitive
                     (color blindness, tritan)"
                     /db_xref="GeneID:12057"
                     /db_xref="MGI:MGI:99438"
     exon            1..444
                     /gene="Opn1sw"
                     /gene_synonym="Bcp"
                     /inference="alignment:Splign:2.1.0"
     exon            445..613
                     /gene="Opn1sw"
                     /gene_synonym="Bcp"
                     /inference="alignment:Splign:2.1.0"
     exon            614..779
                     /gene="Opn1sw"
                     /gene_synonym="Bcp"
                     /inference="alignment:Splign:2.1.0"
     exon            780..1019
                     /gene="Opn1sw"
                     /gene_synonym="Bcp"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..2410
                     /gene="Opn1sw"
                     /gene_synonym="Bcp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1679..1684
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Opn1sw"
                     /gene_synonym="Bcp"
                     /note="hexamer: ATTAAA"
     polyA_site      1697
                     /gene="Opn1sw"
                     /gene_synonym="Bcp"
                     /note="major polyA site"
ORIGIN      
        1 ctgtatcttt aaaggagggt gctgtaggga agggtgatag cagaagaatc gtctataaga
       61 gggaccggag gtggtagtga gggcatccca agcgggagat gtcaggagag gatgactttt
      121 acctgtttca gaatatctct tcggtggggc cctgggatgg gcctcagtac caccttgctc
      181 ctgtctgggc cttccgcctc caggcagcct tcatgggatt tgtcttcttt gtggggaccc
      241 cactcaatgc catagtgctg gtggccacac tgcattacaa aaagttgcga cagcccctca
      301 actatattct ggtcaatgta tccctcgggg gcttcctctt ctgcatcttc tctgtcttca
      361 cagtcttcat cgccagctgt cacggatact tcctctttgg tcgccatgtt tgtgctctgg
      421 aggccttctt gggctctgta gcaggtctag tgacaggatg gtcattggct ttcctggctt
      481 ttgaacgcta cgttgtcatc tgtaaaccct tcggcagcat ccgcttcaac tccaagcatg
      541 cactgatggt ggtcctggct acttggatta ttggtatcgg ggtgtccatc ccaccctttt
      601 ttggctggag caggttcatc cctgagggcc tgcagtgctc ctgtggccca gactggtaca
      661 ctgtgggcac caagtatcga agcgagtact acacctggtt cctcttcatc ttctgtttca
      721 tcattcctct ttccctcatc tgcttctcct actcccagtt gctgaggact ctcagagctg
      781 tggcagctca gcagcaagag tctgctacga cacaaaaggc tgaacgggag gtgagtcata
      841 tggtggtggt gatggtggga tccttctgtc tctgctacgt gccctatgct gccctggcca
      901 tgtacatggt caacaatcgg aaccacgggc tggacttacg gcttgtcacc atccccgcct
      961 tcttttccaa gagctcctgt gtctacaacc ccatcatcta ctgcttcatg aataagcagt
     1021 tccgggcttg cattctggag atggtgtgca ggaagcccat ggcagacgaa tctgacgtgt
     1081 ctggctctca gaaaacagaa gtttctactg tctcttctag caaagttggc cctcactgag
     1141 gcccctcagc tggcctgcta gcagcaaaca caacgccaca tttaagtatc tacatctcca
     1201 ctagaatcct aaccattaac aggggaaaga tggggagtgg tggcactctg gtgagtcacc
     1261 ttcattttcc tgttactctc tgcctgtagc agggccacat ggaccatttt aacagtcaca
     1321 gtttctaagt ggcactctca cctctggaga actgtgagag aagggctgcg tttctggtgt
     1381 atgggtaaca cttccttttt tgctcttttt tttttttttt ctcctccctg ctggggatct
     1441 gagatgatat atccagtatt agaataagct tggcatgggg cagtgccaag aaaaggcagc
     1501 agacaccggg cacctgcagt gaatcgaaga gcttccttat gtggcctctc ccagttgctg
     1561 cagtctgggc tatggctgcc aggatcagaa tggcctcacc tcatttatct gacacagagt
     1621 tattctaggt gttctcccct tcatttggct aaatgtatcc atttaaagct atgcgttgat
     1681 taaagttagt gtcttaatct cttgatgtcc tcaaaatgaa tttgcatgtt tcagtggcat
     1741 ttataaatca agcccaagtg ctaaaaacat cttactttat accctcctta cacctgctgc
     1801 tcctggaaaa ggagcccctc gaaacgaaga agtgcgtgtt gagttatacg caaggagtgc
     1861 tgggtactga tatcaggcac tgaaggtagg aaagccgtag ctgtgagaag gagccagaaa
     1921 tctcaggaat agcaaaggac taagtgtgag ggagaaatgg aagtgataaa agatcacaga
     1981 gatgtatatt tatcttagta acctgagggt taaaggctgg aatacagtaa ttcttaaaga
     2041 ggcccattga taggtaaatg gagttgggaa aattcctttt ctgacatttt atcatagtac
     2101 cctaaaccca tgtctttctt ccttggttct ttctttttac tgatttattt catgtgcatc
     2161 agcgttctgc cagtgtgtgt gactatgtga gtgttggatc ccctgacact ggagttacag
     2221 acagttgtaa gctgctatgt gggtgctgga aattgaaccc aggtcctgag gaagagcaaa
     2281 cagtgctctt aaatgctgag ccatctcttc agcctcttct tggtttcttg agacagagtc
     2341 tctctatgca gccttggctg acctggaata taatcacatt tccaagagaa taaaagacac
     2401 ataagccctt aaaaaaaaaa
//
