LOCUS       NM_053008               2066 bp    mRNA    linear   ROD 11-MAR-2025
DEFINITION  Mus musculus oligodendrocyte transcription factor 3 (Olig3), mRNA.
ACCESSION   NM_053008
VERSION     NM_053008.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2066)
  AUTHORS   Vargas-Ortiz,J., Lin,L., Martinez,V.K., Liu,R.J., Babij,R.,
            Duan,Z.R.S., Wacks,S., Sun,L., Wang,A., Khan,S., Soto-Vargas,J.L.,
            De Marco Garcia,N.V. and Che,A.
  TITLE     Translaminar synchronous neuronal activity is required for columnar
            synaptic strengthening in the mouse neocortex
  JOURNAL   Nat Commun 16 (1), 1296 (2025)
   PUBMED   39900899
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2066)
  AUTHORS   Deska-Gauthier,D., Borowska-Fielding,J., Jones,C., Zhang,H.,
            MacKay,C.S., Michail,R., Bennett,L.A., Bikoff,J.B. and Zhang,Y.
  TITLE     Embryonic temporal-spatial delineation of excitatory spinal V3
            interneuron diversity
  JOURNAL   Cell Rep 43 (1), 113635 (2024)
   PUBMED   38160393
REFERENCE   3  (bases 1 to 2066)
  AUTHORS   Hall,E.T., Dillard,M.E., Cleverdon,E.R., Zhang,Y., Daly,C.A.,
            Ansari,S.S., Wakefield,R., Stewart,D.P., Pruett-Miller,S.M.,
            Lavado,A., Carisey,A.F., Johnson,A., Wang,Y.D., Selner,E.,
            Tanes,M., Ryu,Y.S., Robinson,C.G., Steinberg,J. and Ogden,S.K.
  TITLE     Cytoneme signaling provides essential contributions to mammalian
            tissue patterning
  JOURNAL   Cell 187 (2), 276-293 (2024)
   PUBMED   38171360
REFERENCE   4  (bases 1 to 2066)
  AUTHORS   Sun,X.L., Chen,Z.H., Guo,X., Wang,J., Ge,M., Wong,S.Z.H., Wang,T.,
            Li,S., Yao,M., Johnston,L.A. and Wu,Q.F.
  TITLE     Stem cell competition driven by the Axin2-p53 axis controls brain
            size during murine development
  JOURNAL   Dev Cell 58 (9), 744-759 (2023)
   PUBMED   37054704
REFERENCE   5  (bases 1 to 2066)
  AUTHORS   Balcioglu,A., Gillani,R., Doron,M., Burnell,K., Ku,T., Erisir,A.,
            Chung,K., Segev,I. and Nedivi,E.
  TITLE     Mapping thalamic innervation to individual L2/3 pyramidal neurons
            and modeling their 'readout' of visual input
  JOURNAL   Nat Neurosci 26 (3), 470-480 (2023)
   PUBMED   36732641
REFERENCE   6  (bases 1 to 2066)
  AUTHORS   Muller,T., Anlag,K., Wildner,H., Britsch,S., Treier,M. and
            Birchmeier,C.
  TITLE     The bHLH factor Olig3 coordinates the specification of dorsal
            neurons in the spinal cord
  JOURNAL   Genes Dev 19 (6), 733-743 (2005)
   PUBMED   15769945
  REMARK    GeneRIF: Olig3 expression distinguishes the two major classes of
            progenitors in the dorsal spinal cord and determines the distinct
            specification program of class A neurons.
REFERENCE   7  (bases 1 to 2066)
  AUTHORS   Robinson,K.O., Petersen,A.M., Morrison,S.N., Elso,C.M. and
            Stubbs,L.
  TITLE     Two reciprocal translocations provide new clues to the high
            mutability of the Grid2 locus
  JOURNAL   Mamm Genome 16 (1), 32-40 (2005)
   PUBMED   15674731
REFERENCE   8  (bases 1 to 2066)
  AUTHORS   Takebayashi,H., Ohtsuki,T., Uchida,T., Kawamoto,S., Okubo,K.,
            Ikenaka,K., Takeichi,M., Chisaka,O. and Nabeshima,Y.
  TITLE     Non-overlapping expression of Olig3 and Olig2 in the embryonic
            neural tube
  JOURNAL   Mech Dev 113 (2), 169-174 (2002)
   PUBMED   11960707
  REMARK    GeneRIF: Olig3 is specifically and transiently expressed in
            different types of progenitors of embryonic central nervous system
            and then disappears in the course of development
REFERENCE   9  (bases 1 to 2066)
  AUTHORS   Martin-Caballero,J., Flores,J.M., Garcia-Palencia,P. and Serrano,M.
  TITLE     Tumor susceptibility of p21(Waf1/Cip1)-deficient mice
  JOURNAL   Cancer Res 61 (16), 6234-6238 (2001)
   PUBMED   11507077
REFERENCE   10 (bases 1 to 2066)
  AUTHORS   Takebayashi,H., Yoshida,S., Sugimori,M., Kosako,H., Kominami,R.,
            Nakafuku,M. and Nabeshima,Y.
  TITLE     Dynamic expression of basic helix-loop-helix Olig family members:
            implication of Olig2 in neuron and oligodendrocyte differentiation
            and identification of a new member, Olig3
  JOURNAL   Mech Dev 99 (1-2), 143-148 (2000)
   PUBMED   11091082
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159708.13.
            
            On Sep 13, 2016 this sequence version replaced NM_053008.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB038698.1, SRR7345562.2542177.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2066              AC159708.13        159822-161887
FEATURES             Location/Qualifiers
     source          1..2066
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 8.33 cM"
     gene            1..2066
                     /gene="Olig3"
                     /gene_synonym="Bhlhb7; bHLHe20; oligo3"
                     /note="oligodendrocyte transcription factor 3"
                     /db_xref="GeneID:94222"
                     /db_xref="MGI:MGI:2149955"
     exon            1..2066
                     /gene="Olig3"
                     /gene_synonym="Bhlhb7; bHLHe20; oligo3"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..912
                     /gene="Olig3"
                     /gene_synonym="Bhlhb7; bHLHe20; oligo3"
                     /note="basic helix-loop-helix domain-containing class B
                     protein 7; oligodendrocyte-specific bHLH transcription
                     factor 3"
                     /codon_start=1
                     /product="oligodendrocyte transcription factor 3"
                     /protein_id="NP_443734.2"
                     /db_xref="CCDS:CCDS35855.1"
                     /db_xref="GeneID:94222"
                     /db_xref="MGI:MGI:2149955"
                     /translation="MNSDSSSVSSRASSPDMDEMYLRDHHHRHHHHHQESRLNSVSST
                     QGDMVQKMPGESLSRAGAKAAGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNL
                     AMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGHHSAF
                     HCGTVGHSAGHPAHAANAVHPVHPILGGALSSGNASSPLSATSLPTIGTIRPPHSLLK
                     APSTPPALQLGSGFQHWAGLPCPCTICQMPPPPHLSALSTANMARLSAESKDLLK"
     regulatory      2042..2047
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Olig3"
                     /gene_synonym="Bhlhb7; bHLHe20; oligo3"
                     /note="hexamer: AATAAA"
     polyA_site      2066
                     /gene="Olig3"
                     /gene_synonym="Bhlhb7; bHLHe20; oligo3"
                     /note="major polyA site"
ORIGIN      
        1 tttttttttt tttttttttt taattcaaga ttctctttaa tttcctgcct aaaggctcct
       61 caaccataag gccgcatctc ttgtaataaa atgaattctg attcgagctc tgtctccagc
      121 agagcgtcat ctccggacat ggatgagatg tacctaagag accaccacca ccgccaccac
      181 caccaccatc aggagagtcg tctgaactcg gtctcctcca cacagggcga tatggtccag
      241 aagatgccag gggaaagcct ctcgagggca ggcgccaagg ctgcaggaga aagcagcaag
      301 tacaaaatca agaagcagct gtcggagcag gatcttcagc agttgcggct gaagatcaac
      361 ggacgcgaac gcaagaggat gcacgacctg aacctcgcca tggatggtct gcgcgaggtc
      421 atgccctacg ctcacgggcc ctcggtgcgc aagctctcca agatcgccac tctgcttctg
      481 gccagaaact acatcctcat gctcaccagc tccctggagg agatgaagag gttggttgga
      541 gagatctacg ggggacacca ctcggccttc cactgtggga ctgtggggca ttcggccggc
      601 cacccggcac acgcagccaa cgctgtgcac ccggtgcacc ctatcctggg cggcgcgctc
      661 tcctctggca atgcctcgtc ccctctgtcc gcgacctccc tgccgaccat tggcaccatc
      721 cgtcctcccc actcactgct caaggcgccc tccacgccgc ccgcgctaca attgggcagc
      781 ggcttccagc actgggcggg gctgccctgt ccctgcacca tctgccagat gccaccaccg
      841 ccgcacctgt ccgctctctc caccgccaac atggcccggc tttcggctga atccaaggac
      901 ttgctcaagt gagccacggg ctggcccggc cgggaggagg aagggagagc tgaggcaggg
      961 gtcgcagtgc cgggccagga gggaaaggga gactgctcgg cctgcgggag ggtgggcgcg
     1021 cggccccagg cctcgccagc gccctacaga tccagattcc agttgaccca ccccagcggg
     1081 gcgtgccaaa accaaactgg aatacctagg tgttagcgaa ggggactgga acccgaagtc
     1141 ctgttttgca tgcatgcttc tttccctcat gccacgccag tatttctcac tgtggtatgc
     1201 tcttgtcaaa actgcatttg ttgtttaacg atgggatcag tggagtttaa aacttgcaaa
     1261 ggaactttgg agttggctct ttctggctgt gttcttatct tggaggaaag atggctatcc
     1321 cttttgtgca aagcaaatgt aaatatttca tcgagctaga tacacttatg attgtctctg
     1381 cccttataga tttttcagag acaatggaga gagagagaga gagagagaga gagagagaga
     1441 gagagagctt gtttcagaat ccaagttttg attctcagcc cagggcatga acctcttatg
     1501 tgggttttcc tttccacgca aacataggtc aagaaaatgc atgcacgctt ctaaatgaat
     1561 cttgtctaaa catgttgtgc gggctatagc gccattttcc ttgtaacaag gatttattag
     1621 tgagctctcc aaagtactcc atatatctgt ctgtggttgt ataaaatgaa aagggggcca
     1681 gagcacagag attcacactc aatgaacatg tgattcttcc cccaagccca tgtctgtctc
     1741 tgtccctcaa atctcattcc aacgttaggg ctgttccaag gggcccacta caaaaccggg
     1801 cctcctctag aagttcatcc tacccccttg ccaaattata ctgcatgcgg ggttgggtcg
     1861 gttacccctc agctttgaaa acacactggg tttttgggga gggggctgcc acttttattt
     1921 tcctgaacat ttgcttgaat attttgttag ggcctcaaag acaatacctg tctttatttt
     1981 ttatatattc ttgataagta tgatatattt attaatacca gtgtttctgg atgagatttc
     2041 aaataaaaga gaacctttaa atccgg
//
