LOCUS       NM_016968               2171 bp    mRNA    linear   ROD 17-SEP-2024
DEFINITION  Mus musculus oligodendrocyte transcription factor 1 (Olig1), mRNA.
ACCESSION   NM_016968
VERSION     NM_016968.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2171)
  AUTHORS   Fu,X.Q., Zhan,W.R., Tian,W.Y., Zeng,P.M. and Luo,Z.G.
  TITLE     Comparative transcriptomic profiling reveals a role for Olig1 in
            promoting axon regeneration
  JOURNAL   Cell Rep 43 (7), 114514 (2024)
   PUBMED   39002126
REFERENCE   2  (bases 1 to 2171)
  AUTHORS   Schmidt,A.L., Kremp,M., Aratake,T., Cui,S., Lin,Y., Zhong,X.,
            Lu,Q.R., Zhang,C., Qiu,M., Aberle,T. and Wegner,M.
  TITLE     The myelination-associated G protein-coupled receptor 37 is
            regulated by Zfp488, Nkx2.2, and Sox10 during oligodendrocyte
            differentiation
  JOURNAL   Glia 72 (7), 1304-1318 (2024)
   PUBMED   38546197
REFERENCE   3  (bases 1 to 2171)
  AUTHORS   Liang,X.G., Hoang,K., Meyerink,B.L., Kc,P., Paraiso,K., Wang,L.,
            Jones,I.R., Zhang,Y., Katzman,S., Finn,T.S., Tsyporin,J., Qu,F.,
            Chen,Z., Visel,A., Kriegstein,A., Shen,Y., Pilaz,L.J. and Chen,B.
  TITLE     A conserved molecular logic for neurogenesis to gliogenesis switch
            in the cerebral cortex
  JOURNAL   Proc Natl Acad Sci U S A 121 (20), e2321711121 (2024)
   PUBMED   38713624
REFERENCE   4  (bases 1 to 2171)
  AUTHORS   Zhang,M., Zhi,N., Feng,J., Liu,Y., Zhang,M., Liu,D., Yuan,J.,
            Dong,Y., Jiang,S., Ge,J., Wu,S. and Zhao,X.
  TITLE     ITPR2 Mediated Calcium Homeostasis in Oligodendrocytes is Essential
            for Myelination and Involved in Depressive-Like Behavior in
            Adolescent Mice
  JOURNAL   Adv Sci (Weinh) 11 (20), e2306498 (2024)
   PUBMED   38476116
REFERENCE   5  (bases 1 to 2171)
  AUTHORS   Zhang,Y., Song,Z., Wu,R., Kong,X., Zhang,H., Li,S., Gong,X.,
            Gong,S., Cheng,J., Yuan,F., Wu,H., Wang,S. and Yuan,Z.
  TITLE     PRRC2B modulates oligodendrocyte progenitor cell development and
            myelination by stabilizing Sox2 mRNA
  JOURNAL   Cell Rep 43 (3), 113930 (2024)
   PUBMED   38507412
REFERENCE   6  (bases 1 to 2171)
  AUTHORS   Martin-Caballero,J., Flores,J.M., Garcia-Palencia,P. and Serrano,M.
  TITLE     Tumor susceptibility of p21(Waf1/Cip1)-deficient mice
  JOURNAL   Cancer Res 61 (16), 6234-6238 (2001)
   PUBMED   11507077
REFERENCE   7  (bases 1 to 2171)
  AUTHORS   Tekki-Kessaris,N., Woodruff,R., Hall,A.C., Gaffield,W., Kimura,S.,
            Stiles,C.D., Rowitch,D.H. and Richardson,W.D.
  TITLE     Hedgehog-dependent oligodendrocyte lineage specification in the
            telencephalon
  JOURNAL   Development 128 (13), 2545-2554 (2001)
   PUBMED   11493571
REFERENCE   8  (bases 1 to 2171)
  AUTHORS   Takebayashi,H., Yoshida,S., Sugimori,M., Kosako,H., Kominami,R.,
            Nakafuku,M. and Nabeshima,Y.
  TITLE     Dynamic expression of basic helix-loop-helix Olig family members:
            implication of Olig2 in neuron and oligodendrocyte differentiation
            and identification of a new member, Olig3
  JOURNAL   Mech Dev 99 (1-2), 143-148 (2000)
   PUBMED   11091082
REFERENCE   9  (bases 1 to 2171)
  AUTHORS   Zhou,Q., Wang,S. and Anderson,D.J.
  TITLE     Identification of a novel family of oligodendrocyte
            lineage-specific basic helix-loop-helix transcription factors
  JOURNAL   Neuron 25 (2), 331-343 (2000)
   PUBMED   10719889
REFERENCE   10 (bases 1 to 2171)
  AUTHORS   Lu,Q.R., Yuk,D., Alberta,J.A., Zhu,Z., Pawlitzky,I., Chan,J.,
            McMahon,A.P., Stiles,C.D. and Rowitch,D.H.
  TITLE     Sonic hedgehog--regulated oligodendrocyte lineage genes encoding
            bHLH proteins in the mammalian central nervous system
  JOURNAL   Neuron 25 (2), 317-329 (2000)
   PUBMED   10719888
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB867931.1, BC046316.1, BQ713413.1 and BU531317.1.
            
            On Feb 17, 2005 this sequence version replaced NM_016968.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK144435.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                BB867931.1         2-42
            42-1185             BC046316.1         1-1144
            1186-1187           BQ713413.1         521-522
            1188-2165           BC046316.1         1148-2125
            2166-2171           BU531317.1         479-484
FEATURES             Location/Qualifiers
     source          1..2171
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 52.67 cM"
     gene            1..2171
                     /gene="Olig1"
                     /gene_synonym="Bhlhb6; bHLHe21; Olg-1; Oligo1"
                     /note="oligodendrocyte transcription factor 1"
                     /db_xref="GeneID:50914"
                     /db_xref="MGI:MGI:1355334"
     exon            1..2171
                     /gene="Olig1"
                     /gene_synonym="Bhlhb6; bHLHe21; Olg-1; Oligo1"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..891
                     /gene="Olig1"
                     /gene_synonym="Bhlhb6; bHLHe21; Olg-1; Oligo1"
                     /note="oligodendrocyte-specific bHLH transcription factor
                     1"
                     /codon_start=1
                     /product="oligodendrocyte transcription factor 1"
                     /protein_id="NP_058664.2"
                     /db_xref="CCDS:CCDS28324.1"
                     /db_xref="GeneID:50914"
                     /db_xref="MGI:MGI:1355334"
                     /translation="MYYAISQARVNAAPATMLRPQRPGDVQLGASLYELVGYRQPPIS
                     SSSSSSSSTASLLPKPAREKAEAPLAEPRGPAPESGGARADAKEEQQQQQLRRKINSR
                     ERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQEL
                     RRALGDGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPETLRPTKYLSLALDEPPC
                     GQFSLPAGGAGSPGLCSCAVCKFPHLVPAGLGLAAVQAQFSK"
     regulatory      2145..2150
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Olig1"
                     /gene_synonym="Bhlhb6; bHLHe21; Olg-1; Oligo1"
                     /note="hexamer: AATAAA"
     polyA_site      2165
                     /gene="Olig1"
                     /gene_synonym="Bhlhb6; bHLHe21; Olg-1; Oligo1"
                     /note="major polyA site"
ORIGIN      
        1 actgtcatcc gccggcacgc aggtccgcgg ggagggcgat ctgccgaccg gcccacccct
       61 gggcgttagt gaagggcgcc ccgggtcgcc ccacagcccc cgccccagat gtactatgcg
      121 atttcccagg cgcgtgtgaa cgcggctccc gcgaccatgt tgcggccaca gcggcctgga
      181 gacgtgcagc tcggggcctc gctgtatgag ctggtgggtt acaggcagcc acctatctcc
      241 tcatcctcat cctcatcctc ttccaccgca tcccttctcc ccaagcctgc gcgcgagaag
      301 gccgaagctc cgctcgctga acctcgggga cctgcgccag agtccggggg cgcccgggcc
      361 gacgccaaag aggaacagca gcagcagcag ctgcggcgca agatcaacag ccgcgagcgg
      421 aagcgcatgc aggacctgaa cttggccatg gacgcgctgc gcgaagttat cctaccctac
      481 tcggcagcgc actgccaggg cgcgccgggc cgcaagctct ccaagattgc cacgctgctg
      541 ctcgcccgca actacatcct gctgctgggt agctcgctgc aggagctgcg ccgcgcgctc
      601 ggcgacggtg cgggacccgc cgccccgcgc ctgctcctcg ctggcctgcc tcttctggct
      661 gccgcgccgg gctctgtgct gctggcaccc ggtgccgtgg gaccccccga aacgctgcgc
      721 cccaccaagt acctgtctct agcgctcgac gagccaccgt gcggccagtt ctctctccca
      781 gctggtggcg cgggtagccc tggcctctgc tcctgtgcgg tgtgcaagtt cccgcatctg
      841 gtccccgccg gcctgggctt ggcagcggtg caggcccagt tctccaagtg agggctggct
      901 gggcccgggg cggagcgcga cctcagccaa tcttcccgcg cccccgcgtc ctggatctag
      961 gcagagctgg ccccagaaag gaggacattt ccagacttct ctcccagacg acagactgta
     1021 gggcgccttc ttccccgccc ccactccctg gcaattaaaa taacccaagc gggtgttcca
     1081 aggagcgatg tagttgcttg ggattctaga tgaatcccac ctgtttagag ccagaagtct
     1141 tcgcatcccc accacaactc acccactggc aggggtgaca acccccacca ccgcgggcta
     1201 ttctcgtatc cgtgagcatc gcggagtcgg ggaggacggt agccggccgg tgcggtataa
     1261 gggggttgcc ctgggtgcag cgaaaggctg cccccagctt ggtttcctgg catgcttccg
     1321 ctccctggcc taagagctgc tccccaacag tgtctaccca gaggggcgtc ctttccttgt
     1381 ccagggcctg agcgcacagg ctcccttgct ctctccagcc aaaccatgcg gatctaggag
     1441 gtctagaaag cccaggccac cggtacaaac atcaagggtg ttacggatgg gccgctctgg
     1501 aaagcccagg gtttccgagc tggatgttac gcgggtgcgc tcggttaccg cgctcggtgg
     1561 ttggggatgc gaagtggaga ggttcctctc cactcccagt tctgtttttc aggctcgccc
     1621 aggtgttttg ttgcagttta tgctccttaa aacctaaaac ccttacttag tctccacttc
     1681 cctaaaggta gcttaaccaa cgtttgagct tgcttgaaaa caaaattcca accacgttcc
     1741 atgccatcgg tgttcggact tactaaaata ggtagcaagg cacgtcgtag cgcaggctta
     1801 taaaattcgg tcattaacgt tctcattaaa gtaagcggag ttgggcgagg atcccaaacc
     1861 gcctacccgc cgcgctgcag gcgggaaggc gctggcactt cacaggctgg tccttaacca
     1921 cagcagtgcg gctgaagaac tccgtggacg cgtgcgcgcg tgggtgccgc gtcttggctt
     1981 gtgactagcg ttaggaaatt acccaagatt attgcataat cttcaccagc ttgctttgat
     2041 tcttttttat gttggaagtt ttgggttgtt gacagtagcc gaatttaact ggcattttat
     2101 ttgacctcta actctgtccc tcctgaactg tacagaaatc acaaaataaa acgtcaacag
     2161 ttgaattttt a
//
