LOCUS       NM_133859               1736 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus olfactomedin-like 3 (Olfml3), mRNA.
ACCESSION   NM_133859
VERSION     NM_133859.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1736)
  AUTHORS   Queen,R., Crosier,M., Eley,L., Kerwin,J., Turner,J.E., Yu,J.,
            Alqahtani,A., Dhanaseelan,T., Overman,L., Soetjoadi,H., Baldock,R.,
            Coxhead,J., Boczonadi,V., Laude,A., Cockell,S.J., Kane,M.A.,
            Lisgo,S. and Henderson,D.J.
  TITLE     Spatial transcriptomics reveals novel genes during the remodelling
            of the embryonic human arterial valves
  JOURNAL   PLoS Genet 19 (11), e1010777 (2023)
   PUBMED   38011284
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1736)
  AUTHORS   Toedebusch,R.G., Lucchesi,C.A., Debebe,E.T., Wittenburg,L.A.,
            Chen,X. and Toedebusch,C.M.
  TITLE     Microglia-Derived Olfactomedin-like 3 Promotes Pro-Tumorigenic
            Microglial Function and Malignant Features of Glioma Cells
  JOURNAL   Int J Mol Sci 22 (23), 13052 (2021)
   PUBMED   34884869
  REMARK    GeneRIF: Microglia-Derived Olfactomedin-like 3 Promotes
            Pro-Tumorigenic Microglial Function and Malignant Features of
            Glioma Cells.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1736)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1736)
  AUTHORS   Imhof,B.A., Ballet,R., Hammel,P., Jemelin,S., Garrido-Urbani,S.,
            Ikeya,M., Matthes,T. and Miljkovic-Licina,M.
  TITLE     Olfactomedin-like 3 promotes PDGF-dependent pericyte proliferation
            and migration during embryonic blood vessel formation
  JOURNAL   FASEB J 34 (11), 15559-15576 (2020)
   PUBMED   32997357
  REMARK    GeneRIF: Olfactomedin-like 3 promotes PDGF-dependent pericyte
            proliferation and migration during embryonic blood vessel
            formation.
REFERENCE   5  (bases 1 to 1736)
  AUTHORS   Naiman,N., Fujioka,K., Fujino,M., Valerius,M.T., Potter,S.S.,
            McMahon,A.P. and Kobayashi,A.
  TITLE     Repression of Interstitial Identity in Nephron Progenitor Cells by
            Pax2 Establishes the Nephron-Interstitium Boundary during Kidney
            Development
  JOURNAL   Dev Cell 41 (4), 349-365 (2017)
   PUBMED   28535371
REFERENCE   6  (bases 1 to 1736)
  AUTHORS   Adams,A.C., Astapova,I., Fisher,F.M., Badman,M.K., Kurgansky,K.E.,
            Flier,J.S., Hollenberg,A.N. and Maratos-Flier,E.
  TITLE     Thyroid hormone regulates hepatic expression of fibroblast growth
            factor 21 in a PPARalpha-dependent manner
  JOURNAL   J Biol Chem 285 (19), 14078-14082 (2010)
   PUBMED   20236931
REFERENCE   7  (bases 1 to 1736)
  AUTHORS   Combes,A.N., Lesieur,E., Harley,V.R., Sinclair,A.H., Little,M.H.,
            Wilhelm,D. and Koopman,P.
  TITLE     Three-dimensional visualization of testis cord morphogenesis, a
            novel tubulogenic mechanism in development
  JOURNAL   Dev Dyn 238 (5), 1033-1041 (2009)
   PUBMED   19334288
REFERENCE   8  (bases 1 to 1736)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   9  (bases 1 to 1736)
  AUTHORS   Ikeya,M., Kawada,M., Nakazawa,Y., Sakuragi,M., Sasai,N., Ueno,M.,
            Kiyonari,H., Nakao,K. and Sasai,Y.
  TITLE     Gene disruption/knock-in analysis of mONT3: vector construction by
            employing both in vivo and in vitro recombinations
  JOURNAL   Int J Dev Biol 49 (7), 807-823 (2005)
   PUBMED   16172977
REFERENCE   10 (bases 1 to 1736)
  AUTHORS   Pfisterer,P., Ehlermann,J., Hegen,M. and Schorle,H.
  TITLE     A subtractive gene expression screen suggests a role of
            transcription factor AP-2 alpha in control of proliferation and
            differentiation
  JOURNAL   J Biol Chem 277 (8), 6637-6644 (2002)
   PUBMED   11741941
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY059553.1 and AK131879.1.
            
            On Feb 3, 2006 this sequence version replaced NM_133859.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK131879.1, AK076084.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                BY059553.1         2-38
            38-1736             AK131879.1         2-1700
FEATURES             Location/Qualifiers
     source          1..1736
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 45.52 cM"
     gene            1..1736
                     /gene="Olfml3"
                     /gene_synonym="2810002E22Rik; HNOEL-iso; mONT3; ONT3"
                     /note="olfactomedin-like 3"
                     /db_xref="GeneID:99543"
                     /db_xref="MGI:MGI:1914877"
     exon            1..180
                     /gene="Olfml3"
                     /gene_synonym="2810002E22Rik; HNOEL-iso; mONT3; ONT3"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..1287
                     /gene="Olfml3"
                     /gene_synonym="2810002E22Rik; HNOEL-iso; mONT3; ONT3"
                     /note="olfactomedin-like protein 3"
                     /codon_start=1
                     /product="olfactomedin-like protein 3 precursor"
                     /protein_id="NP_598620.2"
                     /db_xref="CCDS:CCDS17693.1"
                     /db_xref="GeneID:99543"
                     /db_xref="MGI:MGI:1914877"
                     /translation="MGPSAPLLLLFFLSWTGPLQGQQHHLVEYMERRLAALEERLAQC
                     QDQSSRHAAELRDFKNKMLPLLEVAEKERETLRTEADSISGRVDRLEREVDYLETQNP
                     ALPCVELDEKVTGGPGAKGKGRRNEKYDMVTDCSYTVAQVRSMKILKRFGGSVGLWTK
                     DPLGPAEKIYVLDGTQNDTAFVFPRLRDFTLAMAARKASRIRVPFPWVGTGQLVYGGF
                     LYYARRPPGGPGGGGELENTLQLIKFHLANRTVVDSSVFPAESLIPPYGLTADTYIDL
                     AADEEGLWAVYATRDDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVV
                     YNTRPASRARIQCSFDASGTLAPERAALSYFPRRYGAHASLRYNPRERQLYAWDDGYQ
                     IVYKLEMKKKEEEV"
     exon            181..466
                     /gene="Olfml3"
                     /gene_synonym="2810002E22Rik; HNOEL-iso; mONT3; ONT3"
                     /inference="alignment:Splign:2.1.0"
     exon            467..1736
                     /gene="Olfml3"
                     /gene_synonym="2810002E22Rik; HNOEL-iso; mONT3; ONT3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1714..1719
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Olfml3"
                     /gene_synonym="2810002E22Rik; HNOEL-iso; mONT3; ONT3"
                     /note="hexamer: ATTAAA"
     polyA_site      1733
                     /gene="Olfml3"
                     /gene_synonym="2810002E22Rik; HNOEL-iso; mONT3; ONT3"
                     /note="major polyA site"
ORIGIN      
        1 agagctaacg ggctggaggg aaagaggccg aatgcacaca ctcctctggc cccacttaag
       61 gctgccatgg ggcccagtgc tcctctgctg ctcctcttct ttttgtcatg gacgggaccc
      121 cttcagggac agcagcacca ccttgtggag tacatggaac gccgactagc tgccttagag
      181 gaacggctgg cccaatgcca ggatcagagt agtcggcatg ctgccgagct tcgggacttc
      241 aaaaacaaga tgttgcctct cctggaggtg gcagagaagg agcgggagac cctcagaact
      301 gaagcagact ccatctcagg aagagtggac cgtcttgaaa gggaggtaga ctatctggag
      361 acacagaacc cagctttgcc ctgtgtagag ctggatgaga aggtgactgg aggtcctgga
      421 gccaaaggca agggccgaag aaatgagaaa tacgatatgg tgacggactg tagctacaca
      481 gtcgctcagg tgaggtcaat gaagatcctg aagcggtttg gtggttcagt tggcctatgg
      541 accaaggatc cgctggggcc agcagagaag atctacgtgt tagacggcac ccagaacgac
      601 acggcttttg tcttcccaag gctgcgtgac ttcacccttg ccatggctgc ccggaaagct
      661 tcccgaattc gggtgccctt cccctgggta ggcacggggc agctggtgta cggtggcttc
      721 ctttattatg ctcgaaggcc tcctggagga cctggagggg gtggtgaatt ggagaacact
      781 ctgcagctga tcaaatttca cttggcaaac cgaacagtgg tggatagctc agtgttccct
      841 gcagagagcc tgataccccc ctacggcctg acagcagata catatatcga cctggcagct
      901 gatgaggagg gcctgtgggc tgtctatgcc actcgagatg atgacaggca tttgtgtcta
      961 gccaagttag acccacagac acttgacaca gagcagcagt gggacacacc atgtcccaga
     1021 gagaacgcag aggctgcgtt tgtcatctgt gggaccctgt acgttgtcta taacacccgc
     1081 cctgccagta gggctcgtat tcagtgttcc ttcgatgcca gtggtactct cgcccctgaa
     1141 agggcagcac tctcctattt tccacgccga tatggtgccc atgccagcct tcgctataac
     1201 ccccgtgagc gccagctgta tgcctgggat gatggctacc agattgtcta caaattggag
     1261 atgaagaaga aggaggagga agtttaagca gctagccttg tgctcttgat tcttatgccc
     1321 agacatttat attcctgtga gctctcctgc agttcatcct tcaaaacgaa ggccagtggt
     1381 ggtagctcat ataccctaat ttctaaagga caaccaaatt ctcaagcccc tctgttttat
     1441 gcagaactcc agatcctggg tagcatttta gaactgaaca gcaaacaaac accctaaatc
     1501 ttcactcctg ccttatgtcc acaaagttta gttccaaact cagagccctg tcctttggag
     1561 agggtcaacc ccagacagca ggcgacagca ttcttgccct cagtatgacc gaagggagag
     1621 aactcagaga caaagctgcc ctccctccct tccccctcca gtgtagggga gaatggggct
     1681 ttccccacat cactttgtat ggtaacagtt tgcattaaaa ggaaaaccca ccattc
//
