LOCUS       NM_001404301            3099 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus olfactomedin-like 2B (Olfml2b), transcript variant 1,
            mRNA.
ACCESSION   NM_001404301 XM_006496901
VERSION     NM_001404301.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3099)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3099)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3099)
  AUTHORS   Abonnenc,M., Nabeebaccus,A.A., Mayr,U., Barallobre-Barreiro,J.,
            Dong,X., Cuello,F., Sur,S., Drozdov,I., Langley,S.R., Lu,R.,
            Stathopoulou,K., Didangelos,A., Yin,X., Zimmermann,W.H., Shah,A.M.,
            Zampetaki,A. and Mayr,M.
  TITLE     Extracellular matrix secretion by cardiac fibroblasts: role of
            microRNA-29b and microRNA-30c
  JOURNAL   Circ Res 113 (10), 1138-1147 (2013)
   PUBMED   24006456
REFERENCE   4  (bases 1 to 3099)
  AUTHORS   Manabe,R., Tsutsui,K., Yamada,T., Kimura,M., Nakano,I., Shimono,C.,
            Sanzen,N., Furutani,Y., Fukuda,T., Oguri,Y., Shimamoto,K.,
            Kiyozumi,D., Sato,Y., Sado,Y., Senoo,H., Yamashina,S., Fukuda,S.,
            Kawai,J., Sugiura,N., Kimata,K., Hayashizaki,Y. and Sekiguchi,K.
  TITLE     Transcriptome-based systematic identification of extracellular
            matrix proteins
  JOURNAL   Proc Natl Acad Sci U S A 105 (35), 12849-12854 (2008)
   PUBMED   18757743
REFERENCE   5  (bases 1 to 3099)
  AUTHORS   Furutani,Y., Manabe,R., Tsutsui,K., Yamada,T., Sugimoto,N.,
            Fukuda,S., Kawai,J., Sugiura,N., Kimata,K., Hayashizaki,Y. and
            Sekiguchi,K.
  TITLE     Identification and characterization of photomedins: novel
            olfactomedin-domain-containing proteins with chondroitin
            sulphate-E-binding activity
  JOURNAL   Biochem J 389 (Pt 3), 675-684 (2005)
   PUBMED   15836428
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125021.12.
            
            On Apr 9, 2022 this sequence version replaced XM_006496901.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17253012.5142523.1,
                                           SRR17253014.4545940.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-564               AC125021.12        95670-96233
            565-828             AC125021.12        98820-99083
            829-936             AC125021.12        100874-100981
            937-1113            AC125021.12        113497-113673
            1114-1345           AC125021.12        117704-117935
            1346-1858           AC125021.12        119889-120401
            1859-2035           AC125021.12        132175-132351
            2036-3099           AC125021.12        132862-133925
FEATURES             Location/Qualifiers
     source          1..3099
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 76.95 cM"
     gene            1..3099
                     /gene="Olfml2b"
                     /gene_synonym="1110018N05Rik; 4832415H08Rik"
                     /note="olfactomedin-like 2B"
                     /db_xref="GeneID:320078"
                     /db_xref="MGI:MGI:2443310"
     exon            1..564
                     /gene="Olfml2b"
                     /gene_synonym="1110018N05Rik; 4832415H08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             391..2637
                     /gene="Olfml2b"
                     /gene_synonym="1110018N05Rik; 4832415H08Rik"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; photomedin-2; olfactomedin-like protein 2B"
                     /codon_start=1
                     /product="olfactomedin-like protein 2B isoform 1
                     precursor"
                     /protein_id="NP_001391230.1"
                     /db_xref="GeneID:320078"
                     /db_xref="MGI:MGI:2443310"
                     /translation="MAYPLPLVLCFALVVAQVWGSTTPPTGTSEPPDVQTVEPTEDDI
                     LQNEADNQENVLSQLLGDYDKVKAVSEGSDCQCKCVVRPLGRDACQRINQGASRKEDF
                     YTVETITSGSSCKCACVAPPSAVNPCEGDFRLQKLREADSRDLKLSTIIDLLEGAFYG
                     LDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDVEEIRTELNKRGKENCSDNT
                     LESMPDIRSALQRDAAAAYAHPEEQYEERFLQEETVSQQINSIELLRTQPLVPPAAMK
                     PQRPLQRQVHLRGRLASKPTVIRGITYYKAKVSEEENDIEEQHDELFSGDSGVDLLIE
                     DQLLRQEDLLTSATRRPATTRHTAAVTTDASIQAAASSSEPAQASASASSFVEPAPQA
                     SDRELLATPQTTTVFPEPTEVMPSTQVSPTTVAHTAVQPLPAMVPGDIFVEALPLVPL
                     LPDTVGTDMPEEEGTAGQEATSAGPILSPEEEDDIRNVIGRCKDTLSTITGPTTQNTY
                     GRNEGAWMKDPLAKDDRIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPYSWIGTGH
                     VVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEEATPWRWQGHSDVDFAVDE
                     NGLWLIYPALDDEGFNQEVIVLSKLNAVDLSTQKETTWRTGLRRNFYGNCFVICGVLY
                     AVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQV
                     TYHVIFAY"
     exon            565..828
                     /gene="Olfml2b"
                     /gene_synonym="1110018N05Rik; 4832415H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            829..936
                     /gene="Olfml2b"
                     /gene_synonym="1110018N05Rik; 4832415H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1113
                     /gene="Olfml2b"
                     /gene_synonym="1110018N05Rik; 4832415H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1345
                     /gene="Olfml2b"
                     /gene_synonym="1110018N05Rik; 4832415H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1346..1858
                     /gene="Olfml2b"
                     /gene_synonym="1110018N05Rik; 4832415H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1859..2035
                     /gene="Olfml2b"
                     /gene_synonym="1110018N05Rik; 4832415H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2036..3099
                     /gene="Olfml2b"
                     /gene_synonym="1110018N05Rik; 4832415H08Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      3074
                     /gene="Olfml2b"
                     /gene_synonym="1110018N05Rik; 4832415H08Rik"
     regulatory      3076..3081
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Olfml2b"
                     /gene_synonym="1110018N05Rik; 4832415H08Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3099
                     /gene="Olfml2b"
                     /gene_synonym="1110018N05Rik; 4832415H08Rik"
                     /note="major polyA site"
ORIGIN      
        1 agccctccct tgcctcctgc gctgtggcca ctgtccatct tgcgcccagt ctccgggtgt
       61 cccgagtttc ccggcgctag ccttccacct gagctcacgc tgctgcggct tgccctcgtc
      121 gagccggcgc cctcctctgc tccctcagtc acctctttct tgtgtcctct ctgcacagtc
      181 taagctgctg gggtctggga ggagatgttc agggtctctg gggagcacag tcctgctcca
      241 ctcagccaca cccagcttta gacgttagac ggttctctga acatctactc ttccggactc
      301 cagtgaagcc gccttccagc ctgtctttgc tgagacctcc gacccaaggt ggtctctgta
      361 gggactaaag tccctactgt cgcatctctc atggcctatc ccctgccatt ggttctctgc
      421 tttgctctgg tggtggcaca ggtctggggg tccactacac ctcccacagg gacaagcgag
      481 ccccctgatg tgcaaacagt ggagcccacg gaagatgaca ttctgcaaaa cgaggcggac
      541 aaccaggaga acgttttatc tcagctgctg ggagactatg acaaggtcaa ggctgtgtct
      601 gagggctctg actgtcagtg caagtgtgtg gtgagaccgc tgggccgaga tgcctgccag
      661 aggatcaacc agggggcttc caggaaggaa gacttctaca ctgtggaaac catcacctcg
      721 ggctcatcct gtaaatgtgc ttgtgttgct cctccgtctg ccgtcaatcc ctgtgaggga
      781 gacttcaggc tccagaagct tcgggaggct gacagccgag atttgaagct gtctacaatt
      841 atagacctgt tggaaggtgc tttctacggc ctggacctcc taaagctgca ttcggttacc
      901 actaaactcg tggggcgagt ggataaactg gaggaggaag tctctaagaa cctcaccaag
      961 gagaatgagc aaatcaaaga ggatgtggaa gaaatccgaa cggagctgaa caagcgaggc
     1021 aaggagaact gctctgacaa caccctagag agcatgccag acatccgctc agccctgcag
     1081 agggatgcgg ctgcagccta tgcccaccca gaggagcagt atgaagaacg gtttctgcag
     1141 gaggaaactg tgtcacagca gatcaactcc atcgaactcc tgaggacgca gccactggtc
     1201 cctcctgcag cgatgaagcc gcagcggccc ctgcagagac aggtgcacct gagaggtcgg
     1261 ctggcctcca agcccaccgt catcagggga atcacctact ataaagccaa ggtctctgag
     1321 gaggaaaatg acatagaaga gcagcacgat gagcttttca gtggcgacag tggagtggac
     1381 ttgctgatag aagatcagct tctaagacag gaagacctac tgacaagtgc cacccggagg
     1441 ccagcaacca ctcgtcacac tgctgctgtc acgactgatg cgagcattca ggccgcagcc
     1501 tcatcctcag agcctgcaca ggcctctgcc tcagcatcca gctttgttga gcctgctcct
     1561 caggcctccg atagagagct cttggcaacc ccacagacta ccacagtgtt tccagagccc
     1621 acggaggtga tgccttctac ccaagtctca cccaccaccg tggcccacac agctgtccag
     1681 ccacttccag caatggttcc tggggacata tttgtggaag ctctaccctt ggtccctctg
     1741 ttacctgaca cagttgggac agacatgcca gaggaagagg ggactgcagg gcaggaagca
     1801 acctctgctg gtcccatcct gagccctgaa gaagaagatg acattcggaa tgtgatagga
     1861 aggtgcaagg acaccctctc tacaatcaca ggaccgacca cccagaacac atatggacgg
     1921 aatgaagggg cctggatgaa ggacccccta gccaaggacg accgcattta cgtaaccaac
     1981 tattactatg gcaacacact ggttgagttc cgaaacctgg agaacttcaa acaaggtcgc
     2041 tggagcaatt cctacaagct tccatacagc tggattggca cgggtcacgt ggtctacaac
     2101 ggcgccttct actataaccg ggccttcacc cgaaacatca tcaagtatga cctgaagcag
     2161 cgttatgtgg ctgcctgggc catgctgcac gatgtggcct atgaggaggc cactccttgg
     2221 cggtggcagg gtcactcgga tgtggacttt gctgtggatg agaatggcct gtggcttatc
     2281 tacccagctc tggatgatga aggtttcaac caggaggtca ttgtcctgag caagctcaat
     2341 gccgtggacc tgagcacgca gaaggagacc acgtggcgca ctgggctccg gaggaatttc
     2401 tatggcaact gctttgtcat ctgtggggta ctatatgctg tggacagcta taaccagagg
     2461 aatgccaaca tctcctatgc ctttgacaca cacaccaaca cacagattgt ccctaggctg
     2521 ctgtttgaga atgaatattc gtacaccacc cagatagact acaaccccaa ggaccgcctc
     2581 ctctatgcct gggacaatgg ccaccaggtc acctaccatg tcatctttgc ctactgacac
     2641 acttgaccct gcaaaaagaa gcacagtggg gccactagca ccttgtgtgt gtctgtgtgc
     2701 gtgtctgtct gtgagattgt gcaggtgggt gtgtgttgtt ttaaaatata ttattttgta
     2761 taatattaca agtgtaaaat gacagtttgg gtctatattt tttatatgga ttgtagatca
     2821 atccatatgt gtatgtgctg gtctcatcct tcacaattta tatttttgtg caaatgaact
     2881 tctccttctg accagtaact accttctttc gtgctctgaa cctctgactc ctgaggtcaa
     2941 gggctggagg gtttcttcct ccaggtcttg cagccaggag caggagtgtg gggctcagga
     3001 aaaagtgcta agtggcggca aagtttttat gtattagaga agttcttaaa actcagaaaa
     3061 aaaatacttt tttttaataa aggagatatt ttaagatcc
//
