LOCUS       NM_153157               4436 bp    mRNA    linear   ROD 04-OCT-2024
DEFINITION  Mus musculus olfactomedin 3 (Olfm3), transcript variant 2, mRNA.
ACCESSION   NM_153157
VERSION     NM_153157.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4436)
  AUTHORS   Boudkkazi,S., Schwenk,J., Nakaya,N., Brechet,A., Kollewe,A.,
            Harada,H., Bildl,W., Kulik,A., Dong,L., Sultana,A., Zolles,G.,
            Schulte,U., Tomarev,S. and Fakler,B.
  TITLE     A Noelin-organized extracellular network of proteins required for
            constitutive and context-dependent anchoring of AMPA-receptors
  JOURNAL   Neuron 111 (16), 2544-2556 (2023)
   PUBMED   37591201
REFERENCE   2  (bases 1 to 4436)
  AUTHORS   Schwenk,J., Harmel,N., Brechet,A., Zolles,G., Berkefeld,H.,
            Muller,C.S., Bildl,W., Baehrens,D., Huber,B., Kulik,A., Klocker,N.,
            Schulte,U. and Fakler,B.
  TITLE     High-resolution proteomics unravel architecture and molecular
            diversity of native AMPA receptor complexes
  JOURNAL   Neuron 74 (4), 621-633 (2012)
   PUBMED   22632720
REFERENCE   3  (bases 1 to 4436)
  AUTHORS   Sultana,A., Nakaya,N., Senatorov,V.V. and Tomarev,S.I.
  TITLE     Olfactomedin 2: expression in the eye and interaction with other
            olfactomedin domain-containing proteins
  JOURNAL   Invest Ophthalmol Vis Sci 52 (5), 2584-2592 (2011)
   PUBMED   21228389
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4436)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   5  (bases 1 to 4436)
  AUTHORS   Grinchuk,O., Kozmik,Z., Wu,X. and Tomarev,S.
  TITLE     The Optimedin gene is a downstream target of Pax6
  JOURNAL   J Biol Chem 280 (42), 35228-35237 (2005)
   PUBMED   16115881
  REMARK    GeneRIF: Pax6 regulation of Optimedin in the eye and brain may
            directly affect multiple developmental processes, including cell
            migration and axon growth
REFERENCE   6  (bases 1 to 4436)
  AUTHORS   Torrado,M., Trivedi,R., Zinovieva,R., Karavanova,I. and
            Tomarev,S.I.
  TITLE     Optimedin: a novel olfactomedin-related protein that interacts with
            myocilin
  JOURNAL   Hum Mol Genet 11 (11), 1291-1301 (2002)
   PUBMED   12019210
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161527.18.
            
            On Nov 15, 2013 this sequence version replaced NM_153157.2.
            
            Transcript Variant: This variant (2) uses an alternate 5' terminal
            exon, lacks a portion of the 5' coding region and initiates
            translation at an alternate start codon compared to variant 1. The
            encoded protein (isoform B) has a distinct N-terminus and is longer
            than isoform A.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF442824.1, SRR17784643.155083.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-221               AC161527.18        125130-125350
            222-368             AC161527.18        134246-134392
            369-524             AC161527.18        141041-141196
            525-744             AC161527.18        145969-146188
            745-851             AC161527.18        165059-165165
            852-4436            AC161527.18        166345-169929
FEATURES             Location/Qualifiers
     source          1..4436
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 49.43 cM"
     gene            1..4436
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /note="olfactomedin 3"
                     /db_xref="GeneID:229759"
                     /db_xref="MGI:MGI:2387329"
     exon            1..221
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            222..368
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            369..524
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            525..744
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            745..851
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            852..4436
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3690..3695
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /note="hexamer: AATAAA"
     regulatory      3718..3723
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3723
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /note="major polyA site"
     polyA_site      3734
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /note="major polyA site"
     regulatory      3762..3767
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3785
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
     regulatory      3898..3903
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3923
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
     regulatory      4063..4068
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4086
                     /gene="Olfm3"
                     /gene_synonym="B230206G02Rik"
ORIGIN      
        1 gtagatgtgg cttgctgcag tcacgcctcc cgctgccagc cgggctccgg gatcctaatc
       61 agtcactatg aaaactcatt agctccacag caatgagtgc tccactgctg aaactgggcg
      121 ctgtgctcag taccatggca atgatctcaa actggatgtc ccaaactctc ccatccctgg
      181 taggactgaa caccacaagg ctgtcggcgc cagataccct aactcagatt agccccaaag
      241 aagggtggca agtgtacagc tcagcacagg accctgatgg gcgatgcatt tgtactgtgg
      301 ttgctccaga acaaaacctg tgttccagag atgccaaaag caggcagctt cgccagctac
      361 tggaaaaggt acagaatatg tcacagtcta tagaagtctt aaacttgaga actcagagag
      421 attttcagta tgtcttaaaa atggaaaccc aaatgaaagg gctgaaggcc aagtttcggc
      481 agattgaaga tgatcggaag acgctaatga ccaagcattt tcaagagttg aaagagaaaa
      541 tggatgagct actgcccctg atcccagtgt tggagcagta caaaaccgat gcaaagctca
      601 tcacacagtt caaggaagaa attcggaacc tgtcttcagt cctcactggg attcaggagg
      661 aaattggtgc ctatgactat gaagaacttc atcaacgggt cctcagctta gagaccaggc
      721 ttcgtgactg catgaaaaag ctaacatgtg gcaaattgat gaaaatcaca ggccccatca
      781 cagtcaagac atctggaact cgatttggtg cttggatgac ggatccttta gcatctgaaa
      841 agaataacag agtctggtat atggacagtt ataccaacaa taaaatagtt cgtgaataca
      901 agtccattgc agactttgtg agtggagctg aatcaaggac atacaacctc cctttcaagt
      961 gggcaggaac taaccatgtt gtctacaatg gctctctcta ttttaacaaa tatcagagta
     1021 atatcatcat caagtacagc tttgacttag ggagagtgct agcccaaaga agcctggagt
     1081 acgctggttt tcacaatgtg tacccctata catggggtgg attctctgac attgacctaa
     1141 tggctgatga aattggtctg tgggctgtat atgcaactaa ccagaatgca ggcaatattg
     1201 tcatcagcca gcttaatcaa gataccttgg aggtgatgaa aagctggagc actggctatc
     1261 ccaagagaag tgcaggggaa tccttcatga tctgtgggac tctgtacgtc accaattccc
     1321 acttaacagg agccaaagtg tattattcct attccacaaa aacttccaca tatgagtaca
     1381 cggacatccc cttccataac caatactttc acatatctat gcttgactac aatgcaagag
     1441 atagagctct ttatgcctgg aacaatggcc accaggtcct gttcaatgtt accctgttcc
     1501 acatcattaa gactgaagat gacacatagg caaatgtcat gttttcatct ctctactctg
     1561 tcatttatga taaactttat aggaccctgt gtttatcttt ttttctcctt gattggcttg
     1621 tcatcatttc tccaaagcaa aggattttat tgtatatttg gagtttcaaa aagtgtttgt
     1681 ctaagttagt gtgttggaaa tacatcttaa atcccaaatt tacagggcct atcatgccct
     1741 tctcatgaaa agcactaaaa agagtttaag tggccagaat catagttttg caaaagatta
     1801 atgatctgcc ttgtattaga atcagattaa cggtggctta aatgcatgaa tgtcttctct
     1861 ttttaactgt cattattttt actgtctctt ggtctacatc aagaaatatt ttcatagaaa
     1921 ttaaggtaaa agaaaagcac tttcccccca tttatttcta caagaagatt taaagatttt
     1981 atttatatgg gaaacactat caatcatgtt actcttacca tattctctga tgcggtgctg
     2041 tgcagtcatt tctaaatctc ttgctcacat tttcctggca atacatattt ctaccagtgt
     2101 aaccaccatc atatattgta ttccttcact tctgtgaaag tcatattttt tataaagtgc
     2161 actaaaattt aatctcagta attactcaag tcagttctca agtctggttg agaaagatca
     2221 tcttggcttg ccccttctca taagcactac aaaaattttt taaaaaagta ttagataata
     2281 tatatacaac ctttgtttta tccagcactc taccattggc tctggatttg aacaccaatt
     2341 caatgtagtg ataccctgtt tcttaaaaga attcatataa ttctttgtaa aatgtgtcac
     2401 tgtgttatac tcaatatgat tctattcact tatcattatt agtattagta gcatacatat
     2461 atattaatat tttaacatat cttacataca actttcaaaa atgtcatttc ttatacaata
     2521 tgaagcacat gaagattatt aaaaagagga aatttattca atgctttcta tattaaaatt
     2581 ataaaccctg gagagttatt ggaaagcttg tataaaagaa aactatgaaa agaattggga
     2641 gttatttttg tttcaagtgt ataaataacc aattcagaaa attaaatgag aattcaatcc
     2701 cctgagaact tgtctcactg tgtgcgcaaa attaaagaaa ctgaaagtaa aaactttgat
     2761 aacatttgtg ttactaattc cacagaaatt ataatcaaca acttatgaac atgtcaatga
     2821 ggttagaagt aatttcccta tgttaaaaag aattccacta aggcaccttt atggaaacta
     2881 aatttttaaa aatatattct aaaatgaatg acataactta aattgcaatt tttgtctcat
     2941 atgcatacaa aataccacaa ttttaaaata agcagatgat aatgcagaca cagcactcta
     3001 taaaaagaca ctgatattta gagtatttca ttttaagttc tacaagtgaa gggtcattct
     3061 caactaccat cctatcaaac tggagaatct agttactata atcttgaaat tcaagaatga
     3121 atgagcaggt attttgtttt ttgggttttg ttgttgttga tcttattttg ttttgttttg
     3181 tttttttgtc aacaaaagtt aagcatgatc taatgggaac actgcatctt tttataatga
     3241 tgttttcttc tcttaccaaa agttcatgta agctctaggc tacaagtgag agttagaaaa
     3301 tttagaagat tcatttgtca tactacacat atcacaaaag caagcagttc atacttcgta
     3361 taacaatttg tataaggtta aaaaatcatg tcagttttag aaatgaatca atctttaggt
     3421 aggcaaactc taataggaac acttcttgtt tttaagacat gctatgtggt atcacataca
     3481 ttcaaaatat ggatgatcat ggcttttttg tgaggtgtgc gccttgtaca gagccctgtt
     3541 gttttatatg tatggtttca ttgccctatc tatttatagt gtatgtgctg ctagagaagc
     3601 taagatttta ttgtcactag aagtggggta acatgagctt taaaaatatg acttgcatta
     3661 aacactaaca gtttatgagc attttcctta ataaattatg ttcagttttg tgcctgaaat
     3721 aaataagaat ttaatcactg tttccttttt aatttccagc aaataaagta attttatgag
     3781 gaaaataatg agtatcttaa aatcatccat agaatctaag gagtgcagaa gtctattctc
     3841 agaaaaccac catcctaagt aaactatgta actggtattt tctagattaa tcagatcatt
     3901 aaaatacttc catgtcattc aaatagtatg cttgcggttg ggttgtgttg gtgtgtaatt
     3961 catttttgtg gaacttaagt cacaagactt attacttgta tctaaactta aatctacagg
     4021 ttcagaaaat ggcaatcttc cagtgcatta acattttgta gaaataaaag agaaagaaag
     4081 aacaaacact gtgtatgcac agagagtgag tgattagtca tgcattatca taaatctaga
     4141 cgcccagatt gctaccttca ttgcagtttc atttctttat aattgacagc actctcagtg
     4201 atgaaaactt cagaaatata ttaacttctt attgatgttt attacaatta gaaaaacaca
     4261 gccatctctt catgtttgaa agtcactgcc aaatttctga gtagaacttt tacaatcaga
     4321 gtgattgcta ctgaaatata accatataac attaaaaatg tattaccatg aaaataaagt
     4381 tttattataa aaagtaatat ttttattata aaaatactcc tttgtaaatg aatttt
//
