LOCUS       NM_019498               2727 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus olfactomedin 1 (Olfm1), transcript variant 1, mRNA.
ACCESSION   NM_019498 XM_915901 XM_923977 XM_923981 XM_923986 XM_923990
            XM_923993 XM_923996 XM_924001
VERSION     NM_019498.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2727)
  AUTHORS   Liu,B., Hua,D., Shen,L., Li,T., Tao,Z., Fu,C., Tang,Z., Yang,J.,
            Zhang,L., Nie,A., Jiang,Y., Wang,J., Li,Y., Gu,Y. and Ning,G.
  TITLE     NPC1 is required for postnatal islet beta cell differentiation by
            maintaining mitochondria turnover
  JOURNAL   Theranostics 14 (5), 2058-2074 (2024)
   PUBMED   38505613
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2727)
  AUTHORS   Boudkkazi,S., Schwenk,J., Nakaya,N., Brechet,A., Kollewe,A.,
            Harada,H., Bildl,W., Kulik,A., Dong,L., Sultana,A., Zolles,G.,
            Schulte,U., Tomarev,S. and Fakler,B.
  TITLE     A Noelin-organized extracellular network of proteins required for
            constitutive and context-dependent anchoring of AMPA-receptors
  JOURNAL   Neuron 111 (16), 2544-2556 (2023)
   PUBMED   37591201
REFERENCE   3  (bases 1 to 2727)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2727)
  AUTHORS   Shimoide,T., Kawao,N., Morita,H., Ishida,M., Takafuji,Y. and
            Kaji,H.
  TITLE     Roles of Olfactomedin 1 in Muscle and Bone Alterations Induced by
            Gravity Change in Mice
  JOURNAL   Calcif Tissue Int 107 (2), 180-190 (2020)
   PUBMED   32462291
  REMARK    GeneRIF: Roles of Olfactomedin 1 in Muscle and Bone Alterations
            Induced by Gravity Change in Mice.
REFERENCE   5  (bases 1 to 2727)
  AUTHORS   Estrada,S.M., Thagard,A.S., Dehart,M.J., Damicis,J.R.,
            Dornisch,E.M., Ippolito,D.L., Burd,I., Napolitano,P.G. and
            Ieronimakis,N.
  TITLE     The orphan nuclear receptor Nr4a1 mediates perinatal
            neuroinflammation in a murine model of preterm labor
  JOURNAL   Cell Death Dis 11 (1), 11 (2020)
   PUBMED   31907354
  REMARK    Erratum:[Cell Death Dis. 2020 Jun 30;11(6):495. doi:
            10.1038/s41419-020-2682-y.. PMID: 32606386]
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2727)
  AUTHORS   Moreno,T.A. and Bronner-Fraser,M.
  TITLE     Neural expression of mouse Noelin-1/2 and comparison with other
            vertebrates
  JOURNAL   Mech Dev 119 (1), 121-125 (2002)
   PUBMED   12385760
  REMARK    GeneRIF: study of noelin expression during mouse development
REFERENCE   7  (bases 1 to 2727)
  AUTHORS   Kulkarni,N.H., Karavanich,C.A., Atchley,W.R. and Anholt,R.R.
  TITLE     Characterization and differential expression of a human gene family
            of olfactomedin-related proteins
  JOURNAL   Genet Res 76 (1), 41-50 (2000)
   PUBMED   11006633
REFERENCE   8  (bases 1 to 2727)
  AUTHORS   Nagano,T., Nakamura,A., Konno,D., Kurata,M., Yagi,H. and Sato,M.
  TITLE     A2-Pancortins (Pancortin-3 and -4) are the dominant pancortins
            during neocortical development
  JOURNAL   J Neurochem 75 (1), 1-8 (2000)
   PUBMED   10854240
REFERENCE   9  (bases 1 to 2727)
  AUTHORS   Karavanich,C.A. and Anholt,R.R.
  TITLE     Molecular evolution of olfactomedin
  JOURNAL   Mol Biol Evol 15 (6), 718-726 (1998)
   PUBMED   9615453
REFERENCE   10 (bases 1 to 2727)
  AUTHORS   Nagano,T., Nakamura,A., Mori,Y., Maeda,M., Takami,T., Shiosaka,S.,
            Takagi,H. and Sato,M.
  TITLE     Differentially expressed olfactomedin-related glycoproteins
            (Pancortins) in the brain
  JOURNAL   Brain Res Mol Brain Res 53 (1-2), 13-23 (1998)
   PUBMED   9473566
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU512660.1, CT010369.1 and AL731778.12.
            
            On Jan 5, 2006 this sequence version replaced NM_019498.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660819.122210.1, D78262.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-717               BU512660.1         6-722
            718-1079            CT010369.1         457-818
            1080-2727           AL731778.12        198428-200075
FEATURES             Location/Qualifiers
     source          1..2727
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 19.38 cM"
     gene            1..2727
                     /gene="Olfm1"
                     /gene_synonym="AMY; Noe1; OlfA; Pancortin; Pancortin3"
                     /note="olfactomedin 1"
                     /db_xref="GeneID:56177"
                     /db_xref="MGI:MGI:1860437"
     exon            1..411
                     /gene="Olfm1"
                     /gene_synonym="AMY; Noe1; OlfA; Pancortin; Pancortin3"
                     /inference="alignment:Splign:2.1.0"
     CDS             262..1719
                     /gene="Olfm1"
                     /gene_synonym="AMY; Noe1; OlfA; Pancortin; Pancortin3"
                     /note="isoform a precursor is encoded by transcript
                     variant 1; olfactomedin related ER localized protein;
                     neuronal olfactomedin-related ER localized protein; Noelin
                     1; Noelin 2; Pancortin 1-4"
                     /codon_start=1
                     /product="noelin isoform a precursor"
                     /protein_id="NP_062371.2"
                     /db_xref="CCDS:CCDS15834.1"
                     /db_xref="GeneID:56177"
                     /db_xref="MGI:MGI:1860437"
                     /translation="MSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTRLSAASGGT
                     LDRSTGVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQ
                     NMSQSIEVLDRRTQRDLQYVEKMENQMKGLETKFKQVEESHKQHLARQFKAIKAKMDE
                     LRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDELQSRVSNLEERL
                     RACMQKLACGKLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVRE
                     YKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTR
                     SLDYAGYNNMYHYAWGGHSDIDLMVDENGLWAVYATNQNAGNIVISKLDPVSLQILQT
                     WNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHIS
                     MLDYNPKDRALYAWNNGHQTLYNVTLFHVIRSDEL"
     exon            412..561
                     /gene="Olfm1"
                     /gene_synonym="AMY; Noe1; OlfA; Pancortin; Pancortin3"
                     /inference="alignment:Splign:2.1.0"
     exon            562..717
                     /gene="Olfm1"
                     /gene_synonym="AMY; Noe1; OlfA; Pancortin; Pancortin3"
                     /inference="alignment:Splign:2.1.0"
     exon            718..937
                     /gene="Olfm1"
                     /gene_synonym="AMY; Noe1; OlfA; Pancortin; Pancortin3"
                     /inference="alignment:Splign:2.1.0"
     exon            938..1044
                     /gene="Olfm1"
                     /gene_synonym="AMY; Noe1; OlfA; Pancortin; Pancortin3"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..2727
                     /gene="Olfm1"
                     /gene_synonym="AMY; Noe1; OlfA; Pancortin; Pancortin3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2707..2712
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Olfm1"
                     /gene_synonym="AMY; Noe1; OlfA; Pancortin; Pancortin3"
                     /note="hexamer: AATAAA"
     polyA_site      2727
                     /gene="Olfm1"
                     /gene_synonym="AMY; Noe1; OlfA; Pancortin; Pancortin3"
                     /note="major polyA site"
ORIGIN      
        1 cgcggggacg ctgcagcggc gggcagcgcg ggcaggcagc gcgcgccggg cagggccgcc
       61 tggtcacctc ccggcgccgg ggcggcgcgg cgatggccag tgcgcacagg gaggcagaga
      121 ccggcgggcg gcggcgggca gagggggcgc ggggacgcgg ccgggcgccc ctgcccgccg
      181 tggtgcccgc cgcctgaggc tgcccggggc gcgggagccg gcgccggcgc ggcgcgggcg
      241 caggaggcca ctcgaggcgc gatgtcggtg ccgctgctga agatcggggt cgtgctaagc
      301 accatggcca tgatcaccaa ctggatgtcc cagacgctgc cctcgctggt gggcctcaat
      361 accacccggc tttcggccgc cagcggcggg acgctggacc gcagcaccgg cgtgttgccc
      421 accaaccccg aggagagctg gcaggtgtac agctctgccc aggacagtga gggcaggtgt
      481 atctgcacag tggtcgcccc ccagcagacc atgtgttcgc gggatgcccg cacaaaacag
      541 ctgaggcagc tactggagaa ggtgcaaaac atgtctcaat ccatagaagt cttggacagg
      601 cgaactcaga gagacctgca gtacgtggag aagatggaga accagatgaa aggcctggag
      661 accaagttca agcaggtgga ggagagccat aagcagcatc tagccaggca gttcaaggca
      721 ataaaagcga aaatggatga acttaggcct ttgattcctg tgttggaaga gtacaaggcc
      781 gatgccaaat tggtattgca gtttaaggag gaggtccaga atctgacgtc agtgcttaac
      841 gaactgcaag aggagattgg cgcctatgac tacgatgaac ttcagagcag agtgtccaat
      901 cttgaagaaa ggctccgtgc atgcatgcaa aaactagcct gcgggaagct gacaggcata
      961 agtgacccag tgactgtcaa gacctctggc tcaaggttcg ggtcctggat gacagacccg
     1021 ctggccccag aaggcgataa ccgggtctgg tacatggatg gttatcacaa caaccgcttc
     1081 gtccgtgagt acaagtccat ggtggacttc atgaacacgg acaactttac ctctcaccgt
     1141 ctcccacacc cctggtcagg tacgggccag gtggtctaca atggctccat ctatttcaac
     1201 aaattccaga gtcacattat cattaggttt gacctgaaga cagagacgat tctgaagacg
     1261 cgcagcctgg actatgctgg ctacaacaat atgtatcact atgcctgggg cggccactca
     1321 gacatcgacc tcatggtgga cgagaatggg ctctgggctg tctatgccac aaaccagaac
     1381 gcaggcaaca ttgtcatcag caagctggat cctgtctcac tgcagatcct ccagacctgg
     1441 aacaccagct accccaagcg cagtgccggt gaggccttca tcatctgcgg caccctctat
     1501 gtcaccaacg gttactcggg gggcaccaag gtccactatg cctaccaaac caacgcctcg
     1561 acctacgagt acattgacat ccccttccag aacaaatact ctcacatctc catgctggac
     1621 tacaacccta aagaccgcgc gctgtacgcc tggaacaatg gccatcagac cctctataat
     1681 gtcaccctct tccatgtcat ccgctccgat gagttgtagc tcccactttt ccagaagcca
     1741 agggtccaag tcctcacccc gaggacattt ccatgaaaca gctgccaaat gattccaaga
     1801 atactaacag tcctgatttt gagaaatcag cgcaattttg acgccgagag atggtgtcct
     1861 ctctgtgttc ctcctactcc tgcaggtggg ccgcagattt cagaagaaac cgccatgtat
     1921 gtggatggaa ctgcagccca aggctccttg gctgtcccca tcccacccca tccctctctg
     1981 gtccaataac tcaaagaagc aaggcgatga ctgttggccc ctctcaccca agaacaaccc
     2041 actgttagga ttgcatggac atttccttag gttgtgccca gcgagatgat gtgatggcca
     2101 ttctccccaa ccagctcccc cagcccccga ggcactcgct cagtgtaggc tgcttcagcc
     2161 cacacatatc gcagctgcct ttttcttgac cgtgttgttg tctcttagat taactgtgct
     2221 gagactcccg gtagctcatg gacctgtgtc tagtactttc ccgaagcgat ggtgggtgtg
     2281 cgtaggtgaa gttgctgtac ccacgttgtt gaacttgcgt accctgtagc tagatcgtga
     2341 ggtgtccgtc tgttatcccc caaggtggta actccgtgtg ttcaatttat gcaatgaatg
     2401 ttgtcatgca atgctgtagt ttggattgat aagtggatgg tttctgtttc taaaaagaaa
     2461 aaaaaaatca gtgttcgccc ttataggaga catagtcaag ttcatgttga taataaccca
     2521 gtggaactct tatcttgtca aggtatctga attgtgtaac catggatggg aaggacgcat
     2581 cgtgggaaac ttccgtttcc tacaggaagg aactccccaa gggcagccat gtgtggaaag
     2641 atcatttttt aaagaaataa ataagtcaaa gagggcaact ttgtactgtt cagttatcta
     2701 aggaacaata aagatattag gagataa
//
