LOCUS       NM_025942               2189 bp    mRNA    linear   ROD 31-MAY-2024
DEFINITION  Mus musculus Obg-like ATPase 1 (Ola1), transcript variant 1, mRNA.
ACCESSION   NM_025942
VERSION     NM_025942.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2189)
  AUTHORS   Yoshino,Y., Ogoh,H., Iichi,Y., Sasaki,T., Yoshida,T., Ichimura,S.,
            Nakayama,M., Xi,W., Fujita,H., Kikuchi,M., Fang,Z., Li,X., Abe,T.,
            Futakuchi,M., Nakamura,Y., Watanabe,T. and Chiba,N.
  TITLE     Knockout of Brca1-interacting factor Ola1 in female mice induces
            tumors with estrogen suppressible centrosome amplification
  JOURNAL   Biochim Biophys Acta Mol Basis Dis 1870 (5), 167138 (2024)
   PUBMED   38537683
  REMARK    GeneRIF: Knockout of Brca1-interacting factor Ola1 in female mice
            induces tumors with estrogen suppressible centrosome amplification.
REFERENCE   2  (bases 1 to 2189)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2189)
  AUTHORS   Zhou,J., Wang,R., Zhang,J., Zhu,L., Liu,W., Lu,S., Chen,P., Li,H.,
            Yin,B., Yuan,J., Qiang,B., Shu,P. and Peng,X.
  TITLE     Conserved expression of ultra-conserved noncoding RNA in mammalian
            nervous system
  JOURNAL   Biochim Biophys Acta Gene Regul Mech 1860 (12), 1159-1168 (2017)
   PUBMED   29055695
REFERENCE   4  (bases 1 to 2189)
  AUTHORS   Ding,Z., Liu,Y., Rubio,V., He,J., Minze,L.J. and Shi,Z.Z.
  TITLE     OLA1, a Translational Regulator of p21, Maintains Optimal Cell
            Proliferation Necessary for Developmental Progression
  JOURNAL   Mol Cell Biol 36 (20), 2568-2582 (2016)
   PUBMED   27481995
  REMARK    GeneRIF: Data demonstrate that OLA1 is required for normal
            progression of mammalian development. OLA1 plays an important role
            in promoting cell proliferation at least in part through
            suppression of p21 and organogenesis via factors yet to be
            discovered.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2189)
  AUTHORS   Martinez-Baeza,E., Rojas,E. and Valverde,M.
  TITLE     Metal mixture (As-Cd-Pb)-induced cell transformation is modulated
            by OLA1
  JOURNAL   Mutagenesis 31 (4), 463-473 (2016)
   PUBMED   26984302
  REMARK    GeneRIF: cell transformation induced by the metal mixture NaAsO2,
            CdCl2, and Pb(C2H3O2)2.3H2O through ROS generation was rescued by
            OLA1 knockdown during the initiation stage of morphological
            transformation.
REFERENCE   6  (bases 1 to 2189)
  AUTHORS   Mao,R.F., Rubio,V., Chen,H., Bai,L., Mansour,O.C. and Shi,Z.Z.
  TITLE     OLA1 protects cells in heat shock by stabilizing HSP70
  JOURNAL   Cell Death Dis 4 (2), e491 (2013)
   PUBMED   23412384
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 2189)
  AUTHORS   Bailey,P.J., Klos,J.M., Andersson,E., Karlen,M., Kallstrom,M.,
            Ponjavic,J., Muhr,J., Lenhard,B., Sandelin,A. and Ericson,J.
  TITLE     A global genomic transcriptional code associated with CNS-expressed
            genes
  JOURNAL   Exp Cell Res 312 (16), 3108-3119 (2006)
   PUBMED   16919269
REFERENCE   8  (bases 1 to 2189)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK013055.1, AK010817.1 and BX521012.1.
            
            On Oct 1, 2005 this sequence version replaced NM_025942.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK013055.1, AK010817.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-566               AK013055.1         2-567
            567-890             AK010817.1         483-806
            891-2173            AK013055.1         892-2174
            2174-2189           BX521012.1         388-403
FEATURES             Location/Qualifiers
     source          1..2189
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 43.35 cM"
     gene            1..2189
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /note="Obg-like ATPase 1"
                     /db_xref="GeneID:67059"
                     /db_xref="MGI:MGI:1914309"
     exon            1..162
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /inference="alignment:Splign:2.1.0"
     exon            163..263
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /inference="alignment:Splign:2.1.0"
     exon            264..407
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /inference="alignment:Splign:2.1.0"
     exon            408..535
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /inference="alignment:Splign:2.1.0"
     exon            536..711
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /inference="alignment:Splign:2.1.0"
     exon            712..792
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /inference="alignment:Splign:2.1.0"
     exon            793..890
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /inference="alignment:Splign:2.1.0"
     exon            891..1031
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..1128
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /inference="alignment:Splign:2.1.0"
     exon            1129..1251
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..2175
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1756..1761
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /note="hexamer: AATAAA"
     polyA_site      1777
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /note="major polyA site"
     regulatory      2157..2162
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
                     /note="hexamer: ATTAAA"
     polyA_site      2175
                     /gene="Ola1"
                     /gene_synonym="2510025G09Rik; 2810405J23Rik;
                     2810409H07Rik; Gtpbp9; PTD004"
ORIGIN      
        1 aggtgccgcc ccggcccgcc cgttccgtcg cctctgccgt cgtgcgtgcg gctcggcgga
       61 gggccgggct tgcgctctct ccgccttctt ccccacctcc ggctgccggc gacaccggtc
      121 tttgcagtcc gggaccccgt gcgatcgtta gcccggtgca cgatgccccc gaaaaaggga
      181 ggagatggaa ttaaaccgcc tccaattatt ggaagatttg gaacctcact gaaaattggt
      241 atcgttggat tgccaaatgt tgggaagtct accttcttca atgtattaac caatagtcag
      301 gcttcagcag aaaacttccc attctgcact attgatccta atgagagcag agtgcctgtg
      361 ccagatgaga ggttcgactt tctttgccag taccataaac cagcaagcaa gattcctgct
      421 ttcctaaatg tagtggatat tgctggcctt gtaaaaggag ctcacaatgg gcagggcttg
      481 gggaatgcct ttttatctca tattagtgcc tgtgatggga tttttcatct aacacgtgct
      541 tttgaagacg atgatatcac gcatgttgaa ggaagtgtag atcccatccg agacatagag
      601 ataattcacg aggagctcca gctgaaggac gaggagatga ttgggcccat tctagacaaa
      661 ctagagaagg tggccgtgag gggaggcgac aagaaactga agcccgagta tgacataatg
      721 tgcaaagtca agtcttgggt tatagatcaa aagaaacctg ttcgcttcta tcatgactgg
      781 aatgacaaag agattgaagt gttgaataaa cacttatttt tgacttcaaa accaatggtc
      841 tacttggtga atctttctga aaaagactat ataagaaaga aaaacaaatg gttgataaaa
      901 attaaagagt gggtggacaa gtatgaccca ggcgccttgg tcattccttt tagtggggcc
      961 ttggaactca agttgcaaga attgagtgct gaggagagac agaagtatct ggaagcgaac
     1021 atgacacaaa gtgctttgcc aaagatcatt aaggctggat ttgcagcact ccaactagaa
     1081 tactttttca ctgcaggccc agatgaagtg cgtgcgtgga ccatcaggaa aggaacgaag
     1141 gctcctcagg ctgcaggaaa gattcacaca gatttcgaaa agggattcat tatggctgaa
     1201 gtaatgaagt atgaagactt taaagacgag ggttctgaaa acgcagtcaa ggctgctgga
     1261 aaatacagac aacaaggcag gaattatatt gttgaagatg gagatattat cttcttcaaa
     1321 tttaatacac ctcagcaacc aaaaaagaaa taaattcagt tattgctaag atcgacgtac
     1381 aacttctaaa atgcatatat tggggcttgg ggggatgggt gttttttaaa ttaaagtttc
     1441 tgaaatctaa agagacaaag ttaggaatgg gaatcttcta caaacaaatt atttttattt
     1501 gttttaaaat tgtaaaatac tatgtacctt caatgaaatg caagttacta agcgtgaaga
     1561 gctttgcttt ctcacgtgat taagacccta ctgcacactg tagaggcttt tcaagccata
     1621 ttactctcct gatgcttcat taatctccat catgtatgcc aggcctgaca cgtttgacag
     1681 tgaagacaat gtggcttgct cctttttgaa tctaaagata atgcatgttt tacagtactc
     1741 cagatgtcta cactcaataa aacatttgac aaaaccagcc ttggtgtgtt tggggatgtc
     1801 tgtattgact gactgtggtg tgttgaatgc gatatggcac ctgctggctg ctgattacag
     1861 aattttaagg cgtgtgtgac gcaggacctg gcagtgtggg gcagctgcag ttgtatctta
     1921 gaagtgagtc tttcatggga attagaagaa gaatatgcct gggattgtct cagaaaagtt
     1981 aattaatttg tagatggaca tttattgaaa gatgacagca atgatactgc agaggttgaa
     2041 gaacagatga ctctggtcag aaaaaaaacc attttgtctc caatgccagt gaattctgat
     2101 tgttgttagt tctctaacca agtggaagcc attttttctc acttttcttt aaaattatta
     2161 aattgtaaaa actgaaaaaa aaaaaaaaa
//
