LOCUS       NM_001081079            4844 bp    mRNA    linear   ROD 11-MAR-2025
DEFINITION  Mus musculus opioid growth factor receptor-like 1 (Ogfrl1),
            transcript variant 2, mRNA.
ACCESSION   NM_001081079 XM_129809
VERSION     NM_001081079.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4844)
  AUTHORS   Kittaka,M., Mizuno,N., Morino,H., Yoshimoto,T., Zhu,T., Liu,S.,
            Wang,Z., Mayahara,K., Iio,K., Kondo,K., Kondo,T., Hayashi,T.,
            Coghlan,S., Teno,Y., Doan,A.A.P., Levitan,M., Choi,R.B.,
            Matsuda,S., Ouhara,K., Wan,J., Cassidy,A.M., Pelletier,S.,
            Nampoothiri,S., Urtizberea,A.J., Robling,A.G., Ono,M., Kawakami,H.,
            Reichenberger,E.J. and Ueki,Y.
  TITLE     Loss-of-function OGFRL1 variants identified in autosomal recessive
            cherubism families
  JOURNAL   JBMR Plus 8 (6), ziae050 (2024)
   PUBMED   38699440
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4844)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4844)
  AUTHORS   Oeschger,F.M., Wang,W.Z., Lee,S., Garcia-Moreno,F., Goffinet,A.M.,
            Arbones,M.L., Rakic,S. and Molnar,Z.
  TITLE     Gene expression analysis of the embryonic subplate
  JOURNAL   Cereb Cortex 22 (6), 1343-1359 (2012)
   PUBMED   21862448
REFERENCE   4  (bases 1 to 4844)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC165368.5.
            
            On Feb 6, 2007 this sequence version replaced XM_129809.9.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660813.338590.1,
                                           SRR1660821.314923.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-361               AC165368.5         14692-15052
            362-448             AC165368.5         18809-18895
            449-527             AC165368.5         19063-19141
            528-606             AC165368.5         21618-21696
            607-673             AC165368.5         21813-21879
            674-819             AC165368.5         21992-22137
            820-4844            AC165368.5         27419-31443
FEATURES             Location/Qualifiers
     source          1..4844
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 9.57 cM"
     gene            1..4844
                     /gene="Ogfrl1"
                     /gene_synonym="2210417C17Rik"
                     /note="opioid growth factor receptor-like 1"
                     /db_xref="GeneID:70155"
                     /db_xref="MGI:MGI:1917405"
     exon            1..361
                     /gene="Ogfrl1"
                     /gene_synonym="2210417C17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             125..1519
                     /gene="Ogfrl1"
                     /gene_synonym="2210417C17Rik"
                     /note="isoform 2 is encoded by transcript variant 2;
                     opioid growth factor receptor-like protein 1"
                     /codon_start=1
                     /product="opioid growth factor receptor-like protein 1
                     isoform 2"
                     /protein_id="NP_001074548.1"
                     /db_xref="CCDS:CCDS35526.1"
                     /db_xref="GeneID:70155"
                     /db_xref="MGI:MGI:1917405"
                     /translation="MGNLLGGVSFREPTTVEDCDSTWQTDSEPEPEQPGPAGGGEGQQ
                     HDEPEQPKQPPERAGGRPRASPVPEDHAEAAGAEQGGESTEGNAKPKRSFYAARDLYK
                     YRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQ
                     WLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLIDKTGNVA
                     RAGNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNI
                     KQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPKKELPERSKAQKTPTLPA
                     SGSNGQTSTHKKSKDSKISPGASHVNSKSVEEKKGASREPGEEADKPSPEPGSGDPKP
                     RNTEKDSAADQSDSPPEKTVPDTAGKGECPTSSEKDGEGEDQSKDSENPENAGCHAEV
                     VAQQNATNPQTSSG"
     exon            362..448
                     /gene="Ogfrl1"
                     /gene_synonym="2210417C17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            449..527
                     /gene="Ogfrl1"
                     /gene_synonym="2210417C17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            528..606
                     /gene="Ogfrl1"
                     /gene_synonym="2210417C17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            607..673
                     /gene="Ogfrl1"
                     /gene_synonym="2210417C17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            674..819
                     /gene="Ogfrl1"
                     /gene_synonym="2210417C17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            820..4844
                     /gene="Ogfrl1"
                     /gene_synonym="2210417C17Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2670..2675
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ogfrl1"
                     /gene_synonym="2210417C17Rik"
                     /note="hexamer: AGTAAA"
     polyA_site      2693
                     /gene="Ogfrl1"
                     /gene_synonym="2210417C17Rik"
     regulatory      4812..4817
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ogfrl1"
                     /gene_synonym="2210417C17Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4832
                     /gene="Ogfrl1"
                     /gene_synonym="2210417C17Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcggccgcgc tgagctgtgc ggcgcgggcc gggcgagcag ccgcctgcgc cccgagcgag
       61 cggagcgcgg ccatgcccgg gccctagcgc gctaccgcag cccgcgcccg ccgccgcctc
      121 ttcaatgggc aacctgctcg gcggggtcag cttccgcgag cccaccaccg tggaggactg
      181 cgactccacc tggcagaccg attcggagcc cgagcccgag cagccggggc cggcaggcgg
      241 tggcgagggc cagcagcacg acgagccgga gcagcccaag caacctcccg agagagccgg
      301 agggcggccc cgcgccagcc ccgtgcccga ggaccacgcc gaggcggcgg gcgcggagca
      361 gggcggcgag tccacggaag gaaatgccaa accaaagaga agcttctatg ccgcgaggga
      421 tctgtacaag taccgacatc agtacccaaa cttcaaagat atccgatatc aaaatgactt
      481 gagcaacctt cgcttttata agaacaaaat tccatttaag ccggatggtg tttacattga
      541 agaggttcta aataagtgga aaggggacta cgagaagctg gagcacaacc acacgtacat
      601 ccaatggctt ttccccctga gagaacaagg cttgaacttt tatgctaaag aattaaccac
      661 atatgaaatc gaggaattca aaaaaacaaa ggaagcaatc agaagattcc tcttggctta
      721 taaaatgatg ctagagtttt ttggaataaa gctgattgat aagactggaa atgttgctcg
      781 ggccggaaac tggcaagaaa gatttcaaca tcttaatgag tctcagcaca actatttaag
      841 aattacgcga attcttaaaa gccttggcga gcttggatac gagagtttta aatctcctct
      901 ggtaaaattc attcttcacg aggctctagt ggagaatact attcccaata ttaagcagag
      961 tgctctggag tactttgttt atacaattag agacaggaga gagaggagaa agctcctgcg
     1021 atttgcccag aaacattaca caccatcaga gaatttcatc tgggggccac ctaagaaaga
     1081 actgccagag cgaagcaaag cccagaaaac cccgactctg cccgcgtcgg gctccaatgg
     1141 tcaaacttct acacacaaga aatccaagga ctccaaaatt tccccaggag ctagtcacgt
     1201 aaatagcaaa tcagtggaag aaaaaaaggg ggcatcaaga gagcctgggg aggaggcgga
     1261 caagccgagc ccagagcctg gcagtggaga tcccaagcca agaaacacag agaaagacag
     1321 tgctgctgac caatctgatt ctccacccga gaaaacagtt cctgataccg caggaaaagg
     1381 ggaatgtcca acttcttctg aaaaagatgg agaaggggaa gaccagagca aagactctga
     1441 aaatcctgaa aatgccggtt gtcatgctga ggtagtggca cagcaaaatg ccacaaaccc
     1501 acaaaccagt tctggttaaa gaagtaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1561 aaaaaaaact gctttctaat gtgtcctgaa gaacagaaat gaggtcacat ttaaaatgtt
     1621 ggccacctgt gacttttgct gtaagccttt ttattttgga tcacaatgaa ttggacatta
     1681 aataagaagt tttaagacca gatccaataa aagaatacat ttaggatgtg ttttcaaatt
     1741 ctgtatataa cagtcacttt aaaaatagtt tcaagttatc tagatgcagt tccatagcat
     1801 ttggtattca acacgttctc gtgagagatt cctgcagaca tcaagacctc tggtgatgcg
     1861 gcagcacctg gtttttagac tagtgaagga tgctgcgtga ggtgtgccca aatgtttcca
     1921 gaaactagtc tggattccct gattacagcg cctctgtgct cttagctttg gtggctgctc
     1981 tggctggtcc ttccttccca ttggtctgct gtcctcgtct tccccactct gcttgcctgg
     2041 gcatcaccat ctctctcagc ctccacacga gtgttctagt acatgttagg atcctctcct
     2101 gtaccagtgt ccaggtgtaa cagacaggat ttttactagt ctgatttcgg gatttttttt
     2161 atgttcataa taataaaaat attctcagta ttgtttagaa aggatttttt tgtgtgtatg
     2221 tgaaaaaagg aacaaaaata gacttgtttt ttggtggctg ttctatacaa aattgatagt
     2281 tgatcatgga tgcacatcac tgaggaatat tataaaaatc acaaaaaatt agtcattttg
     2341 aaaagatgac tctttatatt gtcaacaagc aaattgtcct ttgacccatt agtgtagtga
     2401 tgccctgagg cctatgctga tgtcaccagt ccacggtgtc tatacatgtc tatgcatctt
     2461 catgtatcat gtgtatgttc atctcatctt catgcactgt gtctatgttc atcttccagt
     2521 attgtgtgtg tatgtttatc ttcatgtatt atatgtgtat atttatcttc atgtattgtg
     2581 tgtatatgtt tatcttcaag tattgtacat tcatcttcca tttgccattt gaaattgaga
     2641 acagtttgaa gttatatata ccgactttaa gtaaatatta gatttgcata gcattggttg
     2701 aaagttttat tttctacagt gttattgtta attattagta caaatcagaa gacaatcaga
     2761 aacactgtga tagcaacttc agaacattca tacagacaaa atgatgaaca gaaaatattt
     2821 ttactttttt ttttaactga gcaaagaact gacttaaaaa atctctcttc agcttttcag
     2881 aaaagcccca tatgttttcc cccaccccac ccgcacaccc cagggaacgt ttcctatttc
     2941 cttttcgtag tacatataat cgtcttcttg gcttcttcag cccacaactt tcagtggtga
     3001 ttcctacaaa acactcccac tattcttagg ttaggttttt agaaataaga ttttattgtt
     3061 tattgttcga tatacacagc ccagttattt atccctactt tatttgtgca ccatagtggc
     3121 acaaatatga tacatactta tttgtgaatc atatccctgt aagtaagaca agaaacactt
     3181 cctcattcta ggtacataat acaccagctt tagcttgtac cgatttgtga ggtgttaaga
     3241 ttttgaggta gtaatcttgg tttaaattcg gtttaatgca aggagttcat gggctctctt
     3301 atgtggtatt tgtagcaaca gtctaaagat cttagtagac atttatacag ggttcaggaa
     3361 tgagagagga ttgccaactc aggatgagtt gtagggatat gagcaattaa ataatatatt
     3421 acttttgaac acacaatgaa acattcagac catgttaaag gtatttagta taaaaacatg
     3481 ggactaggag actagagaga tgactcggtg ataaagagct cttgttgctc ttccagagga
     3541 ccagggttca actctctgtg cctatatgga gagatcacaa tagcctctac taccaggaga
     3601 tctggctccc tgctctggct tctgggggca gtgggacctg catgcatgtg gtgcacatac
     3661 atacacactc aagcgcatac atacacagaa ataacttttt aaaatagaca tggagtcaga
     3721 tactaaaaat attttttctt aaaaaccaag ctaccagata ctaaagttaa tacaatacaa
     3781 attacttaga agttacagta tgccagaacc cttagaaata aaaacactta acaatttaga
     3841 ttctagagta ttattcctta ttagtggtgt tgttaggtta tgctatttaa tttgagaata
     3901 cttagtctct agaggagtac accctggctt tcatccaaaa tagtggcctt tttcttgcag
     3961 cagttattta aactgcgtcc tcgtaacatg acaacgtttc ctacatttaa tctgtaaata
     4021 gcagagaaaa tagtgaagaa caagttgaag taagtcattc ctcatgctga taaaaattga
     4081 gcatctcgaa ttttttctat taagagcact ttgtacattt aatagttttt taacatcaga
     4141 tctatagacg atgtgtttat gtgtgtgttc gctatcaagc agtggtccaa atttgactta
     4201 gctgttttgt gtttctccaa ccatcatatg cttacagtaa ttgactgaga agctgttcca
     4261 ggagatgctg tgcagcatgg ccaagtagtt agatgcattg ctgagcatcc acaggtgttt
     4321 tcatgtggtc tttgttgtac ccaaagcggc aaggatacaa agtatcaact gtcgataaaa
     4381 ttgcatttca caacaaatag atgctatatt gcttgattag cttggtgcag ttctaatatt
     4441 ttttttttgc tttcatattt cagaggagaa aatatatgtg aagatatttt gaaatactat
     4501 aaagtgataa atagttctat atttctgtat ggtggagatg tttctgacat taagattatt
     4561 gtattgttct gtgttttcca gatcattctc ataggaaatt ttaaatgatc atgacttgaa
     4621 aaaaataata tctgctttct ctaaatcgag gcttattgtc agttctaaaa ttaaattgta
     4681 gagttttatt ttgtttaggt tttgaaatta taatttttag ttttaaggaa tgaagaccta
     4741 caactcagga gttactaaga aagttttaag acttgttttt tgatgttaca tatataaata
     4801 aatgaatgtg taataaaaac ctgtcatagc catggtgcat tgta
//
