LOCUS       NM_001374182            3711 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus outer dense fiber of sperm tails 2 (Odf2), transcript
            variant 13, mRNA.
ACCESSION   NM_001374182 XM_030248327
VERSION     NM_001374182.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3711)
  AUTHORS   Ma,Y., Wu,B., Chen,Y., Ma,S., Wang,L., Han,T., Lin,X., Yang,F.,
            Liu,C., Zhao,J. and Li,W.
  TITLE     CCDC146 is required for sperm flagellum biogenesis and male
            fertility in mice
  JOURNAL   Cell Mol Life Sci 81 (1), 1 (2023)
   PUBMED   38038747
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3711)
  AUTHORS   Xu,X., Jiang,X., Song,K., Zhang,J., Tian,Y., Chen,Y., Weng,J.,
            Liang,Y. and Ma,W.
  TITLE     Stable expression and multi-site location of Odf2 in mouse oocytes,
            sperm and early embryos
  JOURNAL   Ann Anat 250, 152126 (2023)
   PUBMED   37364712
  REMARK    GeneRIF: Stable expression and multi-site location of Odf2 in mouse
            oocytes, sperm and early embryos.
REFERENCE   3  (bases 1 to 3711)
  AUTHORS   Xie,Z., Ma,X.H., Bai,Q.F., Tang,J., Sun,J.H., Jiang,F., Guo,W.,
            Wang,C.M., Yang,R., Wen,Y.C., Wang,F.Y., Chen,Y.X., Zhang,H.,
            He,D.Z., Kelley,M.W., Yang,S. and Zhang,W.J.
  TITLE     ZBTB20 is essential for cochlear maturation and hearing in mice
  JOURNAL   Proc Natl Acad Sci U S A 120 (24), e2220867120 (2023)
   PUBMED   37279265
REFERENCE   4  (bases 1 to 3711)
  AUTHORS   Cao,H., Xu,H., Zhou,Y., Xu,W., Lu,Q., Jiang,L., Rong,Y., Zhang,Q.
            and Yu,C.
  TITLE     BBOF1 is required for sperm motility and male fertility by
            stabilizing the flagellar axoneme in mice
  JOURNAL   Cell Mol Life Sci 80 (6), 152 (2023)
   PUBMED   37198331
  REMARK    GeneRIF: BBOF1 is required for sperm motility and male fertility by
            stabilizing the flagellar axoneme in mice.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3711)
  AUTHORS   Lu,Z.L., Shan,X.D., DU,J., Zhu,S.M., Zhuang,J., Liang,X. and
            Zhao,Q.M.
  TITLE     [Impacts of ODF2 gene knockdown on the sperm motility and fertility
            of male mice]
  JOURNAL   Zhonghua Nan Ke Xue 28 (10), 867-872 (2022)
   PUBMED   37838951
  REMARK    GeneRIF: [Impacts of ODF2 gene knockdown on the sperm motility and
            fertility of male mice].
REFERENCE   6  (bases 1 to 3711)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 3711)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   8  (bases 1 to 3711)
  AUTHORS   Hoyer-Fender,S., Petersen,C., Brohmann,H., Rhee,K. and
            Wolgemuth,D.J.
  TITLE     Mouse Odf2 cDNAs consist of evolutionary conserved as well as
            highly variable sequences and encode outer dense fiber proteins of
            the sperm tail
  JOURNAL   Mol Reprod Dev 51 (2), 167-175 (1998)
   PUBMED   9740324
REFERENCE   9  (bases 1 to 3711)
  AUTHORS   Shao,X., Murthy,S., Demetrick,D.J. and van der Hoorn,F.A.
  TITLE     Human outer dense fiber gene, ODF2, localizes to chromosome 9q34
  JOURNAL   Cytogenet Cell Genet 83 (3-4), 221-223 (1998)
   PUBMED   10072582
REFERENCE   10 (bases 1 to 3711)
  AUTHORS   Nakayama,H., Liu,Y., Stifani,S. and Cross,J.C.
  TITLE     Developmental restriction of Mash-2 expression in trophoblast
            correlates with potential activation of the notch-2 pathway
  JOURNAL   Dev Genet 21 (1), 21-30 (1997)
   PUBMED   9291577
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928926.9.
            
            On Sep 12, 2019 this sequence version replaced XM_030248327.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.1450057.1,
                                           SRR13422586.23566.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-105               AL928926.9         68286-68390
            106-196             AL928926.9         70655-70745
            197-313             AL928926.9         71507-71623
            314-382             AL928926.9         71913-71981
            383-553             AL928926.9         79546-79716
            554-714             AL928926.9         80650-80810
            715-844             AL928926.9         81790-81919
            845-976             AL928926.9         82445-82576
            977-1048            AL928926.9         91038-91109
            1049-1120           AL928926.9         92700-92771
            1121-1237           AL928926.9         92863-92979
            1238-1423           AL928926.9         93203-93388
            1424-1533           AL928926.9         93677-93786
            1534-1669           AL928926.9         96079-96214
            1670-1780           AL928926.9         99244-99354
            1781-1885           AL928926.9         99473-99577
            1886-2044           AL928926.9         100682-100840
            2045-2145           AL928926.9         102008-102108
            2146-2308           AL928926.9         104409-104571
            2309-2434           AL928926.9         105173-105298
            2435-3711           AL928926.9         108939-110215
FEATURES             Location/Qualifiers
     source          1..3711
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 20.79 cM"
     gene            1..3711
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /note="outer dense fiber of sperm tails 2"
                     /db_xref="GeneID:18286"
                     /db_xref="MGI:MGI:1098824"
     exon            1..105
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            106..196
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            197..313
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     CDS             206..2626
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /note="isoform i is encoded by transcript variant 13;
                     outer dense fiber protein 2; cenexin; 84 kDa outer dense
                     fiber protein; outer dense fiber of sperm tails protein 2"
                     /codon_start=1
                     /product="outer dense fiber protein 2 isoform i"
                     /protein_id="NP_001361111.1"
                     /db_xref="CCDS:CCDS89462.1"
                     /db_xref="GeneID:18286"
                     /db_xref="MGI:MGI:1098824"
                     /translation="MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAASSQKSHKRGMK
                     GDTVNVRRSVRVKTKNPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKK
                     IDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIE
                     RIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMT
                     CTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGTLLKRLAEA
                     DSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEA
                     ENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKS
                     EEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVN
                     QQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQL
                     KASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQ
                     SQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMA
                     REKHQASQKENKQLSQKVDELERKLEATSAQNVEFLQVIAKREEAIHQAQLRLEEKTR
                     ECGSLARQLESAIEDARRQVEQTKEQALSKERAAQSKILDLETQLSRTKTELGQLRRT
                     RDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKASYANVFGDAPYTSSYLTSSP
                     IRSRSPPA"
     exon            314..382
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            383..553
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            554..714
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            715..844
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            845..976
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1048
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1120
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1121..1237
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1423
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1533
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1534..1669
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1670..1780
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1781..1885
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..2044
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            2045..2145
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            2146..2308
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            2309..2434
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            2435..3711
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3693..3698
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /note="hexamer: AATAAA"
     polyA_site      3711
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /note="major polyA site"
ORIGIN      
        1 gggagccgga ctgcatccgc cgcggcgtct ccatggcacg accctggcct ccgacttcaa
       61 cgacttcata aggagacggt tctgggcgca gccgtgccgc tcttggtttc catcgtgtgg
      121 gaagaacgga gtaacgagtc tcacacagaa aaaagtcttg agaacacctt gtggcgcacc
      181 cagtgtaact gttacgaagt gaaccatgaa ggaccgatct tcaactcccc ccttacatgt
      241 tcacgtggat gagaacactc ctgtccacgt ccacataaaa aaactcccga aaccgtcagc
      301 agccagcagc cagaaatctc ataagcgcgg aatgaaaggg gacaccgtga atgtacggcg
      361 gagtgtccgg gtgaaaacca agaatccacc tcattgcctg gagatcacac caccatcttc
      421 agaaaagctg gtctcggtga tgcgattaag tgacctttct acagaagacg acgattcagg
      481 tcactgtaaa atgaaccgtt acgataagaa gattgacagt ctaatgaacg cggtcggttg
      541 tctcaaatct gaggtcaaga tgcagaaagg tgaacgccaa atggccaaaa ggttcctgga
      601 ggagaggaag gaagagctgg aggaggtggc acacgagctt gcagagacgg agcatgagaa
      661 cacggtgctc agacacaaca tcgagcgtat caaggaggag aaggacttca ccatgcttca
      721 aaagaaacac ctccagcagg agaaggaatg cctcatgtcc aaactagtgg aggctgaaat
      781 ggatggagca gctgctgcca agcaggtcat ggccttgaag gataccatcg ggaagctgaa
      841 aaccgagaaa cagatgactt gcaccgacat caacacctta acaaggcaga aggaacttct
      901 cctgcagaag ctgagtacct ttgaggagac caatcgcacc ctccgagatc tgttgaggga
      961 acagcactgc aaagaggatt ccgagagact aatggagcaa caaggtacat tactgaagcg
     1021 tctggcagag gcagactcag agaaagcgcg cctgctgtta ctactgcaag acaaggacaa
     1081 ggaggtggaa gaactcctcc aggagataca atgtgaaaag gctcaagcaa agacagcgtc
     1141 tgagctttcc aagtccatgg agtccatgcg ggggcatttg caggcacagc ttcgctgcaa
     1201 agaggctgag aacagtcgcc tgtgcatgca gatcaagaac ttagagcgca gtgggaacca
     1261 gcataaggcg gaagtagagg ccatcatgga gcagctaaag gaactgaagc agaagggaga
     1321 ccgagacaaa gagaccctaa agaaggccat ccgagcccag aaagagcgag ccgagaagag
     1381 tgaggagtat gccgagcagc tgcatgtgca actggccgac aaggaccttt atgttgctga
     1441 agctttatct actctggagt cttggaggag ccgttacaac caggttgtga aggacaaagg
     1501 agatcttgag ttggagatta tcgtcctaaa tgaccgggtg acagatcttg taaaccaaca
     1561 acaaagcttg gaggagaaga tgcgggaaga ccgggacagc ttggtagaga ggctgcaccg
     1621 gcagacggct gagtactctg cattcaagct agagaacgag aggctcaagg ctagctttgc
     1681 ccctatggag gacaagctca accaggctca cttggaggtt cagcagctga aggcgtcagt
     1741 gaagaactac gaggggatga tagacaacta caagagccag gtgatgaaaa caagattgga
     1801 ggctgatgaa gtggctgcac agctagagcg ctgcgacaaa gagaacaaga tgcttaaaga
     1861 cgagatgaac aaagagatcg aggcggcccg tcggcagttc cagtcacagc tggctgacct
     1921 acaacagctg cctgacatcc tcaagatcac ggaggccaag ctggctgagt gccaagacca
     1981 gctgcagggc tacgagagga agaacatcga cctcacagcc atcatttcag acctgcgcag
     2041 ccggatcgaa catcaggggg acaagctgga gatggcgaga gagaaacatc aggcttccca
     2101 gaaggaaaat aaacagctga gtcagaaggt ggatgaactt gagaggaaac tggaggctac
     2161 cagcgcccag aatgtcgagt tcctacaggt gattgccaag agggaggagg caatccacca
     2221 ggctcagctg cggttggagg agaaaacgag ggagtgtggg tcattggcga ggcagttgga
     2281 gagtgccatt gaagatgcca ggcgacaggt ggagcaaacc aaggaacagg cactctccaa
     2341 ggaacgagca gcccagagca aaatcctgga ccttgagact cagctgagca ggaccaagac
     2401 agaacttggc cagctgcggc ggactcgtga tgatgcggat cgcagatacc agagccgcct
     2461 gcaggatctg aaagatcgcc tggagcagtc tgagagtacc aaccgcagca tgcagaatta
     2521 tgtccaattc ctcaaggcct cttatgcaaa tgtgtttggg gatgctccct atacatcctc
     2581 ctacctgacg agctcaccca tccgctcccg atcgccccct gcctgaggcc acctgtccag
     2641 ggtgtgatgc ccgtgcctga cgccagacaa ctgtggagtt agcaaaccat agctggcaag
     2701 cccactcgtt ttcaaatgtg ctcagggtct gttcctccac taatgccagg aaggctccta
     2761 gagcagccag ggatgagtca ggaacaatct ggttatcttt cctgacctgg gaacctggtg
     2821 gaattctcta atcctcacag ccgtgcattt gccacattag gtaccagatt ttgaaatccc
     2881 tggaacttta catacagagt ctgcttcctt tcctcaggga atgtttggac ggactgttcc
     2941 atgcagactc cttccagccc tcctctttcc aggcatctct ctcttggggt tttttgagct
     3001 aaagttgcag gaatccttct ccactgaatg cctacattgc cttttctttc ctttttattt
     3061 atttattttt tattttattt ttttaataaa aatagaactt tatttgtatc aagaaatagt
     3121 gaaaacaggt aaattagtat ctgaggtaaa ttagtcaggg ctcatggaga tgagatgttc
     3181 acggctccct tgctcctgtg gaatctgtag ctacgaatgt catgaaaata aatacattgt
     3241 ttgcgtccct cattacatag caactggcat agtcccagct acagcaggtg tgttcacaat
     3301 gaactgtttg gacacagacc taacagtggc aagtgtgctt gtaaccatgt ggtctggttt
     3361 cacagttctg ggaactgcaa ctcccagcct cttactccag gaacaatacc caacggtgtc
     3421 atccttgcgc aggggccatg gtgatctgta ttgttccagc tgtagtggat gctctgctga
     3481 aggggagtca gcttttctcc tcctggtggg tcctgcagga agcagtgttc tccttggtgc
     3541 ccggggaaac ctcccatgtc tgtttcctat aggccacttg ttcctcacga ccatccggcc
     3601 tgacaatcag aattcctatc tcattgcttg tcagttctct ttgtatctct gggattcctt
     3661 tatttttgaa atttttgtgt ggttttacag gaaataaagt ttgtatcact a
//
