LOCUS       NM_001374180            3768 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus outer dense fiber of sperm tails 2 (Odf2), transcript
            variant 11, mRNA.
ACCESSION   NM_001374180 XM_030248311
VERSION     NM_001374180.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3768)
  AUTHORS   Ma,Y., Wu,B., Chen,Y., Ma,S., Wang,L., Han,T., Lin,X., Yang,F.,
            Liu,C., Zhao,J. and Li,W.
  TITLE     CCDC146 is required for sperm flagellum biogenesis and male
            fertility in mice
  JOURNAL   Cell Mol Life Sci 81 (1), 1 (2023)
   PUBMED   38038747
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3768)
  AUTHORS   Xu,X., Jiang,X., Song,K., Zhang,J., Tian,Y., Chen,Y., Weng,J.,
            Liang,Y. and Ma,W.
  TITLE     Stable expression and multi-site location of Odf2 in mouse oocytes,
            sperm and early embryos
  JOURNAL   Ann Anat 250, 152126 (2023)
   PUBMED   37364712
  REMARK    GeneRIF: Stable expression and multi-site location of Odf2 in mouse
            oocytes, sperm and early embryos.
REFERENCE   3  (bases 1 to 3768)
  AUTHORS   Xie,Z., Ma,X.H., Bai,Q.F., Tang,J., Sun,J.H., Jiang,F., Guo,W.,
            Wang,C.M., Yang,R., Wen,Y.C., Wang,F.Y., Chen,Y.X., Zhang,H.,
            He,D.Z., Kelley,M.W., Yang,S. and Zhang,W.J.
  TITLE     ZBTB20 is essential for cochlear maturation and hearing in mice
  JOURNAL   Proc Natl Acad Sci U S A 120 (24), e2220867120 (2023)
   PUBMED   37279265
REFERENCE   4  (bases 1 to 3768)
  AUTHORS   Cao,H., Xu,H., Zhou,Y., Xu,W., Lu,Q., Jiang,L., Rong,Y., Zhang,Q.
            and Yu,C.
  TITLE     BBOF1 is required for sperm motility and male fertility by
            stabilizing the flagellar axoneme in mice
  JOURNAL   Cell Mol Life Sci 80 (6), 152 (2023)
   PUBMED   37198331
  REMARK    GeneRIF: BBOF1 is required for sperm motility and male fertility by
            stabilizing the flagellar axoneme in mice.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3768)
  AUTHORS   Lu,Z.L., Shan,X.D., DU,J., Zhu,S.M., Zhuang,J., Liang,X. and
            Zhao,Q.M.
  TITLE     [Impacts of ODF2 gene knockdown on the sperm motility and fertility
            of male mice]
  JOURNAL   Zhonghua Nan Ke Xue 28 (10), 867-872 (2022)
   PUBMED   37838951
  REMARK    GeneRIF: [Impacts of ODF2 gene knockdown on the sperm motility and
            fertility of male mice].
REFERENCE   6  (bases 1 to 3768)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 3768)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   8  (bases 1 to 3768)
  AUTHORS   Hoyer-Fender,S., Petersen,C., Brohmann,H., Rhee,K. and
            Wolgemuth,D.J.
  TITLE     Mouse Odf2 cDNAs consist of evolutionary conserved as well as
            highly variable sequences and encode outer dense fiber proteins of
            the sperm tail
  JOURNAL   Mol Reprod Dev 51 (2), 167-175 (1998)
   PUBMED   9740324
REFERENCE   9  (bases 1 to 3768)
  AUTHORS   Shao,X., Murthy,S., Demetrick,D.J. and van der Hoorn,F.A.
  TITLE     Human outer dense fiber gene, ODF2, localizes to chromosome 9q34
  JOURNAL   Cytogenet Cell Genet 83 (3-4), 221-223 (1998)
   PUBMED   10072582
REFERENCE   10 (bases 1 to 3768)
  AUTHORS   Nakayama,H., Liu,Y., Stifani,S. and Cross,J.C.
  TITLE     Developmental restriction of Mash-2 expression in trophoblast
            correlates with potential activation of the notch-2 pathway
  JOURNAL   Dev Genet 21 (1), 21-30 (1997)
   PUBMED   9291577
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928926.9.
            
            On Sep 12, 2019 this sequence version replaced XM_030248311.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17253012.3687593.1,
                                           SRR17784650.903346.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-105               AL928926.9         68286-68390
            106-196             AL928926.9         70655-70745
            197-313             AL928926.9         71507-71623
            314-439             AL928926.9         71913-72038
            440-610             AL928926.9         79546-79716
            611-771             AL928926.9         80650-80810
            772-901             AL928926.9         81790-81919
            902-1033            AL928926.9         82445-82576
            1034-1105           AL928926.9         91038-91109
            1106-1177           AL928926.9         92700-92771
            1178-1294           AL928926.9         92863-92979
            1295-1480           AL928926.9         93203-93388
            1481-1590           AL928926.9         93677-93786
            1591-1726           AL928926.9         96079-96214
            1727-1837           AL928926.9         99244-99354
            1838-1942           AL928926.9         99473-99577
            1943-2101           AL928926.9         100682-100840
            2102-2202           AL928926.9         102008-102108
            2203-2365           AL928926.9         104409-104571
            2366-2491           AL928926.9         105173-105298
            2492-3768           AL928926.9         108939-110215
FEATURES             Location/Qualifiers
     source          1..3768
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 20.79 cM"
     gene            1..3768
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /note="outer dense fiber of sperm tails 2"
                     /db_xref="GeneID:18286"
                     /db_xref="MGI:MGI:1098824"
     exon            1..105
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            106..196
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            197..313
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     CDS             206..2683
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /note="isoform a is encoded by transcript variant 11;
                     outer dense fiber protein 2; cenexin; 84 kDa outer dense
                     fiber protein; outer dense fiber of sperm tails protein 2"
                     /codon_start=1
                     /product="outer dense fiber protein 2 isoform a"
                     /protein_id="NP_001361109.1"
                     /db_xref="CCDS:CCDS50556.1"
                     /db_xref="GeneID:18286"
                     /db_xref="MGI:MGI:1098824"
                     /translation="MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAASSQKSHKRGMK
                     GDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSD
                     LSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEV
                     AHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAK
                     QVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKE
                     DSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELS
                     KSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDR
                     DKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDK
                     GDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKA
                     SFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKEN
                     KMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTA
                     IISDLRSRIEHQGDKLEMAREKHQASQKENKQLSQKVDELERKLEATSAQNVEFLQVI
                     AKREEAIHQAQLRLEEKTRECGSLARQLESAIEDARRQVEQTKEQALSKERAAQSKIL
                     DLETQLSRTKTELGQLRRTRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKAS
                     YANVFGDAPYTSSYLTSSPIRSRSPPA"
     exon            314..439
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            440..610
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            611..771
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            772..901
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            902..1033
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1105
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1177
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1178..1294
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1480
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1590
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1591..1726
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1727..1837
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1838..1942
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1943..2101
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            2102..2202
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            2203..2365
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            2366..2491
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            2492..3768
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3750..3755
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /note="hexamer: AATAAA"
     polyA_site      3768
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /note="major polyA site"
ORIGIN      
        1 gggagccgga ctgcatccgc cgcggcgtct ccatggcacg accctggcct ccgacttcaa
       61 cgacttcata aggagacggt tctgggcgca gccgtgccgc tcttggtttc catcgtgtgg
      121 gaagaacgga gtaacgagtc tcacacagaa aaaagtcttg agaacacctt gtggcgcacc
      181 cagtgtaact gttacgaagt gaaccatgaa ggaccgatct tcaactcccc ccttacatgt
      241 tcacgtggat gagaacactc ctgtccacgt ccacataaaa aaactcccga aaccgtcagc
      301 agccagcagc cagaaatctc ataagcgcgg aatgaaaggg gacaccgtga atgtacggcg
      361 gagtgtccgg gtgaaaacca aggtaccttg gatgccccct ggaaaatcat ctgcccggca
      421 tgtgggatgc aagtgggaga atccacctca ttgcctggag atcacaccac catcttcaga
      481 aaagctggtc tcggtgatgc gattaagtga cctttctaca gaagacgacg attcaggtca
      541 ctgtaaaatg aaccgttacg ataagaagat tgacagtcta atgaacgcgg tcggttgtct
      601 caaatctgag gtcaagatgc agaaaggtga acgccaaatg gccaaaaggt tcctggagga
      661 gaggaaggaa gagctggagg aggtggcaca cgagcttgca gagacggagc atgagaacac
      721 ggtgctcaga cacaacatcg agcgtatcaa ggaggagaag gacttcacca tgcttcaaaa
      781 gaaacacctc cagcaggaga aggaatgcct catgtccaaa ctagtggagg ctgaaatgga
      841 tggagcagct gctgccaagc aggtcatggc cttgaaggat accatcggga agctgaaaac
      901 cgagaaacag atgacttgca ccgacatcaa caccttaaca aggcagaagg aacttctcct
      961 gcagaagctg agtacctttg aggagaccaa tcgcaccctc cgagatctgt tgagggaaca
     1021 gcactgcaaa gaggattccg agagactaat ggagcaacaa ggtacattac tgaagcgtct
     1081 ggcagaggca gactcagaga aagcgcgcct gctgttacta ctgcaagaca aggacaagga
     1141 ggtggaagaa ctcctccagg agatacaatg tgaaaaggct caagcaaaga cagcgtctga
     1201 gctttccaag tccatggagt ccatgcgggg gcatttgcag gcacagcttc gctgcaaaga
     1261 ggctgagaac agtcgcctgt gcatgcagat caagaactta gagcgcagtg ggaaccagca
     1321 taaggcggaa gtagaggcca tcatggagca gctaaaggaa ctgaagcaga agggagaccg
     1381 agacaaagag accctaaaga aggccatccg agcccagaaa gagcgagccg agaagagtga
     1441 ggagtatgcc gagcagctgc atgtgcaact ggccgacaag gacctttatg ttgctgaagc
     1501 tttatctact ctggagtctt ggaggagccg ttacaaccag gttgtgaagg acaaaggaga
     1561 tcttgagttg gagattatcg tcctaaatga ccgggtgaca gatcttgtaa accaacaaca
     1621 aagcttggag gagaagatgc gggaagaccg ggacagcttg gtagagaggc tgcaccggca
     1681 gacggctgag tactctgcat tcaagctaga gaacgagagg ctcaaggcta gctttgcccc
     1741 tatggaggac aagctcaacc aggctcactt ggaggttcag cagctgaagg cgtcagtgaa
     1801 gaactacgag gggatgatag acaactacaa gagccaggtg atgaaaacaa gattggaggc
     1861 tgatgaagtg gctgcacagc tagagcgctg cgacaaagag aacaagatgc ttaaagacga
     1921 gatgaacaaa gagatcgagg cggcccgtcg gcagttccag tcacagctgg ctgacctaca
     1981 acagctgcct gacatcctca agatcacgga ggccaagctg gctgagtgcc aagaccagct
     2041 gcagggctac gagaggaaga acatcgacct cacagccatc atttcagacc tgcgcagccg
     2101 gatcgaacat cagggggaca agctggagat ggcgagagag aaacatcagg cttcccagaa
     2161 ggaaaataaa cagctgagtc agaaggtgga tgaacttgag aggaaactgg aggctaccag
     2221 cgcccagaat gtcgagttcc tacaggtgat tgccaagagg gaggaggcaa tccaccaggc
     2281 tcagctgcgg ttggaggaga aaacgaggga gtgtgggtca ttggcgaggc agttggagag
     2341 tgccattgaa gatgccaggc gacaggtgga gcaaaccaag gaacaggcac tctccaagga
     2401 acgagcagcc cagagcaaaa tcctggacct tgagactcag ctgagcagga ccaagacaga
     2461 acttggccag ctgcggcgga ctcgtgatga tgcggatcgc agataccaga gccgcctgca
     2521 ggatctgaaa gatcgcctgg agcagtctga gagtaccaac cgcagcatgc agaattatgt
     2581 ccaattcctc aaggcctctt atgcaaatgt gtttggggat gctccctata catcctccta
     2641 cctgacgagc tcacccatcc gctcccgatc gccccctgcc tgaggccacc tgtccagggt
     2701 gtgatgcccg tgcctgacgc cagacaactg tggagttagc aaaccatagc tggcaagccc
     2761 actcgttttc aaatgtgctc agggtctgtt cctccactaa tgccaggaag gctcctagag
     2821 cagccaggga tgagtcagga acaatctggt tatctttcct gacctgggaa cctggtggaa
     2881 ttctctaatc ctcacagccg tgcatttgcc acattaggta ccagattttg aaatccctgg
     2941 aactttacat acagagtctg cttcctttcc tcagggaatg tttggacgga ctgttccatg
     3001 cagactcctt ccagccctcc tctttccagg catctctctc ttggggtttt ttgagctaaa
     3061 gttgcaggaa tccttctcca ctgaatgcct acattgcctt ttctttcctt tttatttatt
     3121 tattttttat tttatttttt taataaaaat agaactttat ttgtatcaag aaatagtgaa
     3181 aacaggtaaa ttagtatctg aggtaaatta gtcagggctc atggagatga gatgttcacg
     3241 gctcccttgc tcctgtggaa tctgtagcta cgaatgtcat gaaaataaat acattgtttg
     3301 cgtccctcat tacatagcaa ctggcatagt cccagctaca gcaggtgtgt tcacaatgaa
     3361 ctgtttggac acagacctaa cagtggcaag tgtgcttgta accatgtggt ctggtttcac
     3421 agttctggga actgcaactc ccagcctctt actccaggaa caatacccaa cggtgtcatc
     3481 cttgcgcagg ggccatggtg atctgtattg ttccagctgt agtggatgct ctgctgaagg
     3541 ggagtcagct tttctcctcc tggtgggtcc tgcaggaagc agtgttctcc ttggtgcccg
     3601 gggaaacctc ccatgtctgt ttcctatagg ccacttgttc ctcacgacca tccggcctga
     3661 caatcagaat tcctatctca ttgcttgtca gttctctttg tatctctggg attcctttat
     3721 ttttgaaatt tttgtgtggt tttacaggaa ataaagtttg tatcacta
//
