LOCUS       NM_001369060            3921 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus outer dense fiber of sperm tails 2 (Odf2), transcript
            variant 9, mRNA.
ACCESSION   NM_001369060 XM_017316289
VERSION     NM_001369060.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3921)
  AUTHORS   Ma,Y., Wu,B., Chen,Y., Ma,S., Wang,L., Han,T., Lin,X., Yang,F.,
            Liu,C., Zhao,J. and Li,W.
  TITLE     CCDC146 is required for sperm flagellum biogenesis and male
            fertility in mice
  JOURNAL   Cell Mol Life Sci 81 (1), 1 (2023)
   PUBMED   38038747
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3921)
  AUTHORS   Xu,X., Jiang,X., Song,K., Zhang,J., Tian,Y., Chen,Y., Weng,J.,
            Liang,Y. and Ma,W.
  TITLE     Stable expression and multi-site location of Odf2 in mouse oocytes,
            sperm and early embryos
  JOURNAL   Ann Anat 250, 152126 (2023)
   PUBMED   37364712
  REMARK    GeneRIF: Stable expression and multi-site location of Odf2 in mouse
            oocytes, sperm and early embryos.
REFERENCE   3  (bases 1 to 3921)
  AUTHORS   Xie,Z., Ma,X.H., Bai,Q.F., Tang,J., Sun,J.H., Jiang,F., Guo,W.,
            Wang,C.M., Yang,R., Wen,Y.C., Wang,F.Y., Chen,Y.X., Zhang,H.,
            He,D.Z., Kelley,M.W., Yang,S. and Zhang,W.J.
  TITLE     ZBTB20 is essential for cochlear maturation and hearing in mice
  JOURNAL   Proc Natl Acad Sci U S A 120 (24), e2220867120 (2023)
   PUBMED   37279265
REFERENCE   4  (bases 1 to 3921)
  AUTHORS   Cao,H., Xu,H., Zhou,Y., Xu,W., Lu,Q., Jiang,L., Rong,Y., Zhang,Q.
            and Yu,C.
  TITLE     BBOF1 is required for sperm motility and male fertility by
            stabilizing the flagellar axoneme in mice
  JOURNAL   Cell Mol Life Sci 80 (6), 152 (2023)
   PUBMED   37198331
  REMARK    GeneRIF: BBOF1 is required for sperm motility and male fertility by
            stabilizing the flagellar axoneme in mice.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3921)
  AUTHORS   Lu,Z.L., Shan,X.D., DU,J., Zhu,S.M., Zhuang,J., Liang,X. and
            Zhao,Q.M.
  TITLE     [Impacts of ODF2 gene knockdown on the sperm motility and fertility
            of male mice]
  JOURNAL   Zhonghua Nan Ke Xue 28 (10), 867-872 (2022)
   PUBMED   37838951
  REMARK    GeneRIF: [Impacts of ODF2 gene knockdown on the sperm motility and
            fertility of male mice].
REFERENCE   6  (bases 1 to 3921)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 3921)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   8  (bases 1 to 3921)
  AUTHORS   Hoyer-Fender,S., Petersen,C., Brohmann,H., Rhee,K. and
            Wolgemuth,D.J.
  TITLE     Mouse Odf2 cDNAs consist of evolutionary conserved as well as
            highly variable sequences and encode outer dense fiber proteins of
            the sperm tail
  JOURNAL   Mol Reprod Dev 51 (2), 167-175 (1998)
   PUBMED   9740324
REFERENCE   9  (bases 1 to 3921)
  AUTHORS   Shao,X., Murthy,S., Demetrick,D.J. and van der Hoorn,F.A.
  TITLE     Human outer dense fiber gene, ODF2, localizes to chromosome 9q34
  JOURNAL   Cytogenet Cell Genet 83 (3-4), 221-223 (1998)
   PUBMED   10072582
REFERENCE   10 (bases 1 to 3921)
  AUTHORS   Nakayama,H., Liu,Y., Stifani,S. and Cross,J.C.
  TITLE     Developmental restriction of Mash-2 expression in trophoblast
            correlates with potential activation of the notch-2 pathway
  JOURNAL   Dev Genet 21 (1), 21-30 (1997)
   PUBMED   9291577
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928926.9.
            
            On Jan 4, 2022 this sequence version replaced NM_001369060.1.
            
            Transcript Variant: This variant (9), encodes the longest isoform
            (g).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849381,
                              SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-138               AL928926.9         68543-68680
            139-375             AL928926.9         69235-69471
            376-466             AL928926.9         70655-70745
            467-592             AL928926.9         71913-72038
            593-763             AL928926.9         79546-79716
            764-924             AL928926.9         80650-80810
            925-1054            AL928926.9         81790-81919
            1055-1186           AL928926.9         82445-82576
            1187-1258           AL928926.9         91038-91109
            1259-1330           AL928926.9         92700-92771
            1331-1447           AL928926.9         92863-92979
            1448-1633           AL928926.9         93203-93388
            1634-1743           AL928926.9         93677-93786
            1744-1879           AL928926.9         96079-96214
            1880-1990           AL928926.9         99244-99354
            1991-2095           AL928926.9         99473-99577
            2096-2254           AL928926.9         100682-100840
            2255-2355           AL928926.9         102008-102108
            2356-2518           AL928926.9         104409-104571
            2519-2644           AL928926.9         105173-105298
            2645-3921           AL928926.9         108939-110215
FEATURES             Location/Qualifiers
     source          1..3921
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 20.79 cM"
     gene            1..3921
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /note="outer dense fiber of sperm tails 2"
                     /db_xref="GeneID:18286"
                     /db_xref="MGI:MGI:1098824"
     exon            1..138
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            139..375
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     CDS             344..2836
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /note="isoform g is encoded by transcript variant 9; outer
                     dense fiber protein 2; cenexin; 84 kDa outer dense fiber
                     protein; outer dense fiber of sperm tails protein 2"
                     /codon_start=1
                     /product="outer dense fiber protein 2 isoform g"
                     /protein_id="NP_001355989.1"
                     /db_xref="CCDS:CCDS89461.1"
                     /db_xref="GeneID:18286"
                     /db_xref="MGI:MGI:1098824"
                     /translation="MSASSSGGSPRFPSCGKNGVTSLTQKKVLRTPCGAPSVTVTKSH
                     KRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSV
                     MRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKE
                     ELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDG
                     AAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLRE
                     QHCKEDSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKT
                     ASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELK
                     QKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQ
                     VVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLEN
                     ERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLER
                     CDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKN
                     IDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSQKVDELERKLEATSAQNVE
                     FLQVIAKREEAIHQAQLRLEEKTRECGSLARQLESAIEDARRQVEQTKEQALSKERAA
                     QSKILDLETQLSRTKTELGQLRRTRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQ
                     FLKASYANVFGDAPYTSSYLTSSPIRSRSPPA"
     exon            376..466
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            467..592
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            593..763
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            764..924
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1054
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1186
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..1258
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1330
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1447
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1448..1633
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1634..1743
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1744..1879
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1880..1990
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            1991..2095
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            2096..2254
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            2255..2355
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            2356..2518
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            2519..2644
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     exon            2645..3921
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3903..3908
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /note="hexamer: AATAAA"
     polyA_site      3921
                     /gene="Odf2"
                     /gene_synonym="MMTEST29"
                     /note="major polyA site"
ORIGIN      
        1 ccttcctcct cccgctaacg ggcgggccgg ccgcctccgt cctctccggg ccatcggcag
       61 cgctctttcc ctcctctgct gtcctcgggc agggctgcgc ccttctatgg gcagaacccc
      121 gtcccctctt gcccgctgga cagttgctgt gcgacttgga cagtagagga gcgcctccca
      181 agttttcatc caactgccac ccccaaagct tccaccctcc tcccctcaga gagaggacgt
      241 ttgatgcccg gcccctgaga ttctcattgg ccagcccctc tgggtccccc tgagcagagc
      301 ctgccgaccc aattgcccat ctttgcggct ttgatgctta accatgtctg cctcatcctc
      361 aggcggctcc cccaggtttc catcgtgtgg gaagaacgga gtaacgagtc tcacacagaa
      421 aaaagtcttg agaacacctt gtggcgcacc cagtgtaact gttacgaaat ctcataagcg
      481 cggaatgaaa ggggacaccg tgaatgtacg gcggagtgtc cgggtgaaaa ccaaggtacc
      541 ttggatgccc cctggaaaat catctgcccg gcatgtggga tgcaagtggg agaatccacc
      601 tcattgcctg gagatcacac caccatcttc agaaaagctg gtctcggtga tgcgattaag
      661 tgacctttct acagaagacg acgattcagg tcactgtaaa atgaaccgtt acgataagaa
      721 gattgacagt ctaatgaacg cggtcggttg tctcaaatct gaggtcaaga tgcagaaagg
      781 tgaacgccaa atggccaaaa ggttcctgga ggagaggaag gaagagctgg aggaggtggc
      841 acacgagctt gcagagacgg agcatgagaa cacggtgctc agacacaaca tcgagcgtat
      901 caaggaggag aaggacttca ccatgcttca aaagaaacac ctccagcagg agaaggaatg
      961 cctcatgtcc aaactagtgg aggctgaaat ggatggagca gctgctgcca agcaggtcat
     1021 ggccttgaag gataccatcg ggaagctgaa aaccgagaaa cagatgactt gcaccgacat
     1081 caacacctta acaaggcaga aggaacttct cctgcagaag ctgagtacct ttgaggagac
     1141 caatcgcacc ctccgagatc tgttgaggga acagcactgc aaagaggatt ccgagagact
     1201 aatggagcaa caaggtacat tactgaagcg tctggcagag gcagactcag agaaagcgcg
     1261 cctgctgtta ctactgcaag acaaggacaa ggaggtggaa gaactcctcc aggagataca
     1321 atgtgaaaag gctcaagcaa agacagcgtc tgagctttcc aagtccatgg agtccatgcg
     1381 ggggcatttg caggcacagc ttcgctgcaa agaggctgag aacagtcgcc tgtgcatgca
     1441 gatcaagaac ttagagcgca gtgggaacca gcataaggcg gaagtagagg ccatcatgga
     1501 gcagctaaag gaactgaagc agaagggaga ccgagacaaa gagaccctaa agaaggccat
     1561 ccgagcccag aaagagcgag ccgagaagag tgaggagtat gccgagcagc tgcatgtgca
     1621 actggccgac aaggaccttt atgttgctga agctttatct actctggagt cttggaggag
     1681 ccgttacaac caggttgtga aggacaaagg agatcttgag ttggagatta tcgtcctaaa
     1741 tgaccgggtg acagatcttg taaaccaaca acaaagcttg gaggagaaga tgcgggaaga
     1801 ccgggacagc ttggtagaga ggctgcaccg gcagacggct gagtactctg cattcaagct
     1861 agagaacgag aggctcaagg ctagctttgc ccctatggag gacaagctca accaggctca
     1921 cttggaggtt cagcagctga aggcgtcagt gaagaactac gaggggatga tagacaacta
     1981 caagagccag gtgatgaaaa caagattgga ggctgatgaa gtggctgcac agctagagcg
     2041 ctgcgacaaa gagaacaaga tgcttaaaga cgagatgaac aaagagatcg aggcggcccg
     2101 tcggcagttc cagtcacagc tggctgacct acaacagctg cctgacatcc tcaagatcac
     2161 ggaggccaag ctggctgagt gccaagacca gctgcagggc tacgagagga agaacatcga
     2221 cctcacagcc atcatttcag acctgcgcag ccggatcgaa catcaggggg acaagctgga
     2281 gatggcgaga gagaaacatc aggcttccca gaaggaaaat aaacagctga gtcagaaggt
     2341 ggatgaactt gagaggaaac tggaggctac cagcgcccag aatgtcgagt tcctacaggt
     2401 gattgccaag agggaggagg caatccacca ggctcagctg cggttggagg agaaaacgag
     2461 ggagtgtggg tcattggcga ggcagttgga gagtgccatt gaagatgcca ggcgacaggt
     2521 ggagcaaacc aaggaacagg cactctccaa ggaacgagca gcccagagca aaatcctgga
     2581 ccttgagact cagctgagca ggaccaagac agaacttggc cagctgcggc ggactcgtga
     2641 tgatgcggat cgcagatacc agagccgcct gcaggatctg aaagatcgcc tggagcagtc
     2701 tgagagtacc aaccgcagca tgcagaatta tgtccaattc ctcaaggcct cttatgcaaa
     2761 tgtgtttggg gatgctccct atacatcctc ctacctgacg agctcaccca tccgctcccg
     2821 atcgccccct gcctgaggcc acctgtccag ggtgtgatgc ccgtgcctga cgccagacaa
     2881 ctgtggagtt agcaaaccat agctggcaag cccactcgtt ttcaaatgtg ctcagggtct
     2941 gttcctccac taatgccagg aaggctccta gagcagccag ggatgagtca ggaacaatct
     3001 ggttatcttt cctgacctgg gaacctggtg gaattctcta atcctcacag ccgtgcattt
     3061 gccacattag gtaccagatt ttgaaatccc tggaacttta catacagagt ctgcttcctt
     3121 tcctcaggga atgtttggac ggactgttcc atgcagactc cttccagccc tcctctttcc
     3181 aggcatctct ctcttggggt tttttgagct aaagttgcag gaatccttct ccactgaatg
     3241 cctacattgc cttttctttc ctttttattt atttattttt tattttattt ttttaataaa
     3301 aatagaactt tatttgtatc aagaaatagt gaaaacaggt aaattagtat ctgaggtaaa
     3361 ttagtcaggg ctcatggaga tgagatgttc acggctccct tgctcctgtg gaatctgtag
     3421 ctacgaatgt catgaaaata aatacattgt ttgcgtccct cattacatag caactggcat
     3481 agtcccagct acagcaggtg tgttcacaat gaactgtttg gacacagacc taacagtggc
     3541 aagtgtgctt gtaaccatgt ggtctggttt cacagttctg ggaactgcaa ctcccagcct
     3601 cttactccag gaacaatacc caacggtgtc atccttgcgc aggggccatg gtgatctgta
     3661 ttgttccagc tgtagtggat gctctgctga aggggagtca gcttttctcc tcctggtggg
     3721 tcctgcagga agcagtgttc tccttggtgc ccggggaaac ctcccatgtc tgtttcctat
     3781 aggccacttg ttcctcacga ccatccggcc tgacaatcag aattcctatc tcattgcttg
     3841 tcagttctct ttgtatctct gggattcctt tatttttgaa atttttgtgt ggttttacag
     3901 gaaataaagt ttgtatcact a
//
