LOCUS       NM_001177577             759 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus odontogenesis associated phosphoprotein (Odaph), mRNA.
ACCESSION   NM_001177577 XM_355614 XM_905615
VERSION     NM_001177577.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 759)
  AUTHORS   Mu,H., Dong,Z., Wang,Y., Chu,Q., Gao,Y., Wang,A., Wang,Y., Liu,X.
            and Gao,Y.
  TITLE     Odontogenesis-Associated Phosphoprotein (ODAPH) Overexpression in
            Ameloblasts Disrupts Enamel Formation via Inducing Abnormal
            Mineralization of Enamel in Secretory Stage
  JOURNAL   Calcif Tissue Int 111 (6), 611-621 (2022)
   PUBMED   36163390
  REMARK    GeneRIF: Odontogenesis-Associated Phosphoprotein (ODAPH)
            Overexpression in Ameloblasts Disrupts Enamel Formation via
            Inducing Abnormal Mineralization of Enamel in Secretory Stage.
REFERENCE   3  (bases 1 to 759)
  AUTHORS   Ji,Y., Li,C., Tian,Y., Gao,Y., Dong,Z., Xiang,L., Xu,Z., Gao,Y. and
            Zhang,L.
  TITLE     Maturation stage enamel defects in Odontogenesis-associated
            phosphoprotein (Odaph) deficient mice
  JOURNAL   Dev Dyn 250 (10), 1505-1517 (2021)
   PUBMED   33772937
  REMARK    GeneRIF: Maturation stage enamel defects in
            Odontogenesis-associated phosphoprotein (Odaph) deficient mice.
REFERENCE   4  (bases 1 to 759)
  AUTHORS   Liang,T., Hu,Y., Kawasaki,K., Zhang,H., Zhang,C., Saunders,T.L.,
            Simmer,J.P. and Hu,J.C.
  TITLE     Odontogenesis-associated phosphoprotein truncation blocks
            ameloblast transition into maturation in OdaphC41*/C41* mice
  JOURNAL   Sci Rep 11 (1), 1132 (2021)
   PUBMED   33441959
  REMARK    GeneRIF: Odontogenesis-associated phosphoprotein truncation blocks
            ameloblast transition into maturation in Odaph(C41*/C41*) mice.
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC165433.5.
            
            On or before Apr 18, 2010 this sequence version replaced
            XM_905615.2, XM_355614.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB233033.1, SRR14995047.1197895.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                AC165433.5         116892-116977
            87-759              AC165433.5         124064-124736
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 45.68 cM"
     gene            1..759
                     /gene="Odaph"
                     /gene_synonym="Gm1045; Gm1045-a; Gm1045-b"
                     /note="odontogenesis associated phosphoprotein"
                     /db_xref="GeneID:381651"
                     /db_xref="MGI:MGI:2685891"
     exon            1..86
                     /gene="Odaph"
                     /gene_synonym="Gm1045; Gm1045-a; Gm1045-b"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..403
                     /gene="Odaph"
                     /gene_synonym="Gm1045; Gm1045-a; Gm1045-b"
                     /codon_start=1
                     /product="odontogenesis associated phosphoprotein
                     precursor"
                     /protein_id="NP_001171048.1"
                     /db_xref="CCDS:CCDS57356.1"
                     /db_xref="GeneID:381651"
                     /db_xref="MGI:MGI:2685891"
                     /translation="MAPAFHVSWLLVSWLVVTTAEGQDVVTPPGGSQNNAKPTDCQIF
                     TLTPPPTTRNLVTRAQPIPRTPTFSFPPRGPGFSPRFPFFLPNNRRFQFWPFYRPRGR
                     LIPWRLILRRQQQSGSSSEESREN"
     exon            87..759
                     /gene="Odaph"
                     /gene_synonym="Gm1045; Gm1045-a; Gm1045-b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      642..647
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Odaph"
                     /gene_synonym="Gm1045; Gm1045-a; Gm1045-b"
                     /note="hexamer: AATAAA"
     polyA_site      672
                     /gene="Odaph"
                     /gene_synonym="Gm1045; Gm1045-a; Gm1045-b"
                     /note="major polyA site"
ORIGIN      
        1 gtgagtgctc agggcagaag ccatggctcc agctttccat gtctcctggt tactggtcag
       61 ctggttggtg gtaactacag cagaaggaca agatgtagtc acccctcctg gcggctcaca
      121 aaataacgca aagcctacag actgccagat cttcacactc actcctccgc ccaccacaag
      181 gaatctggta acaagggccc agcccatccc aaggacaccc acgttttctt ttccaccaag
      241 ggggccgggc ttctccccga ggttcccttt cttccttcca aacaaccgcc gcttccagtt
      301 ctggccattc tacaggccgc gaggtagact gatcccttgg cgactcatcc ttagaagaca
      361 gcagcagagc ggaagctcat ctgaggagag cagggagaac tgagaagcgc agacttgttg
      421 aagcaaaaga atcggcgcct ctggaaaggg tgatgaaact gtttcgctct ccaatctaaa
      481 atccctgcgt tggaagatta agtaccctca atgacagtga cgagattttt tttctctttc
      541 tttctttttt ttaatcaaca acaaggagtt tggattacac atttttgctt acaaaatctg
      601 gccgtaacgg caccagtctt attccacagg atattagtgc aaataaagtc ttttagtggg
      661 cggttctaat aattttttat ccgtacttgg acaccagcag tattaattaa cctccacttc
      721 caaattagag tgaaggacat tttaatgaga ccgttatga
//
