LOCUS       NM_001171512           24175 bp    mRNA    linear   ROD 06-AUG-2023
DEFINITION  Mus musculus obscurin, cytoskeletal calmodulin and
            titin-interacting RhoGEF (Obscn), transcript variant 1, mRNA.
ACCESSION   NM_001171512 NM_001003914 XM_003689264 XM_126461
VERSION     NM_001171512.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 24175)
  AUTHORS   Pierantozzi E, Szentesi P, Paolini C, Dienes B, Fodor J, Olah T,
            Colombini B, Rassier DE, Rubino EM, Lange S, Rossi D, Csernoch L,
            Bagni MA, Reggiani C and Sorrentino V.
  TITLE     Impaired Intracellular Ca2+ Dynamics, M-Band and Sarcomere
            Fragility in Skeletal Muscles of Obscurin KO Mice
  JOURNAL   Int J Mol Sci 23 (3), 1319 (2022)
   PUBMED   35163243
  REMARK    GeneRIF: Impaired Intracellular Ca(2+) Dynamics, M-Band and
            Sarcomere Fragility in Skeletal Muscles of Obscurin KO Mice.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24175)
  AUTHORS   Grogan A, Coleman A, Joca H, Granzier H, Russel MW, Ward CW and
            Kontrogianni-Konstantopoulos A.
  TITLE     Deletion of obscurin immunoglobulin domains Ig58/59 leads to
            age-dependent cardiac remodeling and arrhythmia
  JOURNAL   Basic Res Cardiol 115 (6), 60 (2020)
   PUBMED   32910221
  REMARK    GeneRIF: Deletion of obscurin immunoglobulin domains Ig58/59 leads
            to age-dependent cardiac remodeling and arrhythmia.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 24175)
  AUTHORS   Hu LR and Kontrogianni-Konstantopoulos A.
  TITLE     Proteomic Analysis of Myocardia Containing the Obscurin R4344Q
            Mutation Linked to Hypertrophic Cardiomyopathy
  JOURNAL   Front Physiol 11, 478 (2020)
   PUBMED   32528308
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 24175)
  AUTHORS   Ford-Speelman DL, Roche JA, Bowman AL and Bloch RJ.
  TITLE     The rho-guanine nucleotide exchange factor domain of obscurin
            activates rhoA signaling in skeletal muscle
  JOURNAL   Mol Biol Cell 20 (17), 3905-3917 (2009)
   PUBMED   19605563
REFERENCE   5  (bases 1 to 24175)
  AUTHORS   Lange S, Ouyang K, Meyer G, Cui L, Cheng H, Lieber RL and Chen J.
  TITLE     Obscurin determines the architecture of the longitudinal
            sarcoplasmic reticulum
  JOURNAL   J Cell Sci 122 (Pt 15), 2640-2650 (2009)
   PUBMED   19584095
REFERENCE   6  (bases 1 to 24175)
  AUTHORS   Bowman AL, Catino DH, Strong JC, Randall WR,
            Kontrogianni-Konstantopoulos A and Bloch RJ.
  TITLE     The rho-guanine nucleotide exchange factor domain of obscurin
            regulates assembly of titin at the Z-disk through interactions with
            Ran binding protein 9
  JOURNAL   Mol Biol Cell 19 (9), 3782-3792 (2008)
   PUBMED   18579686
  REMARK    GeneRIF: the Rho-GEF domain of obscurin interacts with RanBP9 and
            that both can interact with the N-terminal region of titin to
            influence the formation of the Z-disk and A/I junction
REFERENCE   7  (bases 1 to 24175)
  AUTHORS   Borisov AB, Raeker MO and Russell MW.
  TITLE     Developmental expression and differential cellular localization of
            obscurin and obscurin-associated kinase in cardiac muscle cells
  JOURNAL   J Cell Biochem 103 (5), 1621-1635 (2008)
   PUBMED   18041765
  REMARK    Erratum:[J Cell Biochem. 2008 May 1;104(1):357-8]
REFERENCE   8  (bases 1 to 24175)
  AUTHORS   Armani A, Galli S, Giacomello E, Bagnato P, Barone V, Rossi D and
            Sorrentino V.
  TITLE     Molecular interactions with obscurin are involved in the
            localization of muscle-specific small ankyrin1 isoforms to
            subcompartments of the sarcoplasmic reticulum
  JOURNAL   Exp Cell Res 312 (18), 3546-3558 (2006)
   PUBMED   16962094
  REMARK    GeneRIF: Results support a role of obscurin in mediating the
            subcellular localization of small ankyrin1 isoforms in striated
            muscle cells.
REFERENCE   9  (bases 1 to 24175)
  AUTHORS   Sutter SB, Raeker MO, Borisov AB and Russell MW.
  TITLE     Orthologous relationship of obscurin and Unc-89: phylogeny of a
            novel family of tandem myosin light chain kinases
  JOURNAL   Dev Genes Evol 214 (7), 352-359 (2004)
   PUBMED   15185077
REFERENCE   10 (bases 1 to 24175)
  AUTHORS   Bang ML, Centner T, Fornoff F, Geach AJ, Gotthardt M, McNabb M,
            Witt CC, Labeit D, Gregorio CC, Granzier H and Labeit S.
  TITLE     The complete gene sequence of titin, expression of an unusual
            approximately 700-kDa titin isoform, and its interaction with
            obscurin identify a novel Z-line to I-band linking system
  JOURNAL   Circ Res 89 (11), 1065-1072 (2001)
   PUBMED   11717165
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645854.10 and AL662809.14.
            
            [WARNING] On Mar 11, 2024 this sequence was replaced by
            NM_001171512.3.
            
            On or before Jul 6, 2018 this sequence version replaced
            NM_001003914.1, XM_003689264.1, NM_001171512.1.
            
            Summary: The obscurin gene spans more than 150 kb, contains over 80
            exons and encodes a protein of approximately 800 kDa. The encoded
            protein contains 68 Ig domains, 2 fibronectin domains, 1
            calcium/calmodulin-binding domain, 1 RhoGEF domain with an
            associated PH domain, and 2 serine-threonine kinase domains. This
            protein is one of three giant sacromeric signaling proteins that
            includes titin and nebulin. It may have a role in the organization
            of myofibrils during assembly and also may mediate interactions
            between the sarcoplasmic reticulum and myofibrils. Alternatively
            spliced transcript variants encoding different isoforms have been
            described although the full-length nature is not known for all
            splicing variants. [provided by RefSeq, Jan 2010].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer protein (isoform 1). The RefSeq
            Project created this record to better support genomic annotation of
            the full gene length but the combination of exons and splice sites
            still needs to be experimentally confirmed.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence because no single transcript was available for the
            full length of the gene. The genomic coordinates used for the
            transcript record were based on genomic predictions and alignments
            of transcripts from different species.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN00849390 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-982               AL645854.10        118737-119718       c
            983-1252            AL645854.10        117894-118163       c
            1253-1513           AL645854.10        117043-117303       c
            1514-1822           AL645854.10        116364-116672       c
            1823-2089           AL645854.10        115804-116070       c
            2090-2371           AL645854.10        114890-115171       c
            2372-2572           AL645854.10        113784-113984       c
            2573-2848           AL645854.10        111406-111681       c
            2849-3124           AL645854.10        107864-108139       c
            3125-3400           AL645854.10        105963-106238       c
            3401-3676           AL645854.10        99002-99277         c
            3677-3952           AL645854.10        95862-96137         c
            3953-4228           AL645854.10        91085-91360         c
            4229-4504           AL645854.10        89638-89913         c
            4505-4780           AL645854.10        86618-86893         c
            4781-5056           AL645854.10        83033-83308         c
            5057-5332           AL645854.10        76639-76914         c
            5333-5608           AL645854.10        70008-70283         c
            5609-5887           AL645854.10        65960-66238         c
            5888-6154           AL645854.10        65535-65801         c
            6155-6424           AL645854.10        65138-65407         c
            6425-6691           AL645854.10        64040-64306         c
            6692-6958           AL645854.10        63444-63710         c
            6959-7068           AL645854.10        63153-63262         c
            7069-7222           AL645854.10        62900-63053         c
            7223-7327           AL645854.10        62145-62249         c
            7328-7594           AL645854.10        61522-61788         c
            7595-7864           AL645854.10        61024-61293         c
            7865-8131           AL645854.10        60189-60455         c
            8132-8398           AL645854.10        59827-60093         c
            8399-8665           AL645854.10        59477-59743         c
            8666-8938           AL645854.10        58234-58506         c
            8939-9205           AL645854.10        56853-57119         c
            9206-9472           AL645854.10        56450-56716         c
            9473-9745           AL645854.10        53082-53354         c
            9746-10012          AL645854.10        52371-52637         c
            10013-10279         AL645854.10        51287-51553         c
            10280-10543         AL645854.10        50926-51189         c
            10544-10807         AL645854.10        50409-50672         c
            10808-11071         AL645854.10        47530-47793         c
            11072-11290         AL645854.10        46808-47026         c
            11291-11554         AL645854.10        45990-46253         c
            11555-11818         AL645854.10        44767-45030         c
            11819-12082         AL645854.10        44187-44450         c
            12083-12346         AL645854.10        39304-39567         c
            12347-12610         AL645854.10        38117-38380         c
            12611-12877         AL645854.10        35788-36054         c
            12878-13144         AL645854.10        34871-35137         c
            13145-13417         AL645854.10        34474-34746         c
            13418-13693         AL645854.10        33644-33919         c
            13694-13890         AL645854.10        33020-33216         c
            13891-13966         AL645854.10        32768-32843         c
            13967-14239         AL645854.10        27224-27496         c
            14240-14527         AL645854.10        25365-25652         c
            14528-14815         AL645854.10        24908-25195         c
            14816-15189         AL645854.10        23554-23927         c
            15190-16066         AL645854.10        21665-22541         c
            16067-16345         AL645854.10        20878-21156         c
            16346-16424         AL645854.10        20081-20159         c
            16425-16543         AL645854.10        19693-19811         c
            16544-16741         AL645854.10        19290-19487         c
            16742-16774         AL645854.10        18722-18754         c
            16775-16873         AL645854.10        18376-18474         c
            16874-17092         AL645854.10        18038-18256         c
            17093-17153         AL645854.10        17480-17540         c
            17154-17224         AL645854.10        17055-17125         c
            17225-17347         AL645854.10        16237-16359         c
            17348-17487         AL645854.10        15969-16108         c
            17488-17688         AL645854.10        15164-15364         c
            17689-17771         AL645854.10        14925-15007         c
            17772-17945         AL645854.10        14367-14540         c
            17946-18102         AL645854.10        13362-13518         c
            18103-18219         AL645854.10        12813-12929         c
            18220-18384         AL645854.10        12544-12708         c
            18385-18543         AL645854.10        12210-12368         c
            18544-18721         AL645854.10        11840-12017         c
            18722-18835         AL645854.10        10753-10866         c
            18836-19003         AL645854.10        5571-5738           c
            19004-19106         AL645854.10        5208-5310           c
            19107-19236         AL645854.10        4763-4892           c
            19237-19348         AL645854.10        3800-3911           c
            19349-19461         AL662809.14        92981-93093         c
            19462-19630         AL662809.14        92513-92681         c
            19631-19709         AL662809.14        92295-92373         c
            19710-19910         AL662809.14        91996-92196         c
            19911-19971         AL662809.14        91229-91289         c
            19972-20049         AL662809.14        88101-88178         c
            20050-20222         AL662809.14        87679-87851         c
            20223-20249         AL662809.14        87463-87489         c
            20250-20402         AL662809.14        86489-86641         c
            20403-20448         AL662809.14        86351-86396         c
            20449-20526         AL662809.14        85926-86003         c
            20527-22510         AL662809.14        83667-85650         c
            22511-22591         AL662809.14        82953-83033         c
            22592-22684         AL662809.14        82733-82825         c
            22685-22852         AL662809.14        82447-82614         c
            22853-22975         AL662809.14        81635-81757         c
            22976-23146         AL662809.14        81318-81488         c
            23147-23231         AL662809.14        80699-80783         c
            23232-23471         AL662809.14        80260-80499         c
            23472-23695         AL662809.14        79810-80033         c
            23696-23771         AL662809.14        79500-79575         c
            23772-23921         AL662809.14        79157-79306         c
            23922-24175         AL662809.14        78728-78981         c
FEATURES             Location/Qualifiers
     source          1..24175
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 36.4 cM"
     gene            1..24175
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /note="obscurin, cytoskeletal calmodulin and
                     titin-interacting RhoGEF"
                     /db_xref="GeneID:380698"
                     /db_xref="MGI:MGI:2681862"
     CDS             1..24099
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /EC_number="2.7.11.1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     obscurin-MLCK; obscurin-RhoGEF; obscurin-myosin light
                     chain kinase"
                     /codon_start=1
                     /product="obscurin isoform 1"
                     /protein_id="NP_001164983.2"
                     /db_xref="CCDS:CCDS56775.1"
                     /db_xref="GeneID:380698"
                     /db_xref="MGI:MGI:2681862"
                     /translation="MDHSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEK
                     DRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEG
                     TCAEQAPHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVE
                     EHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLL
                     AHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLV
                     TEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPTVPFK
                     KRLQDLEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGTERRLTVRNV
                     SADDDAVYICETTEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELAVPEGPVR
                     WLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQFCVSAPRR
                     PPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGW
                     LATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAVE
                     GGEVTFSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKF
                     VANGIETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKD
                     GRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQDITDGYRD
                     WGPAGPQKHMCKCAGAKIARYLGSSCYRFLQYDKGVWHWLEAALDTRQGKGTSSCSLH
                     EKPKLVFAKGQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEAS
                     GCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGAS
                     ATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAG
                     GQKLSFRLDVTEPKLVFAKEQQARSEVKAEVGNSATLSCEVAQAQTEVTWFKDGKKLS
                     SSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQAR
                     SEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKA
                     DAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEV
                     TWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAEGQKLSFRLDVAEPK
                     LVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSR
                     RLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQANSEVKAEAGASATLS
                     CEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKL
                     SFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSK
                     VRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVK
                     AEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGE
                     YSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFK
                     DGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLFFRLDVAEPKLVFA
                     KEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVV
                     QQVGKADAGEYSCEARGQKLSFRLDVAEAESQIPERPSRREPLVVKEHETIILTATIA
                     APSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCRVGKEGQDFP
                     VQVEEVAAKFSKPLEPVEGELGGTVMLVCELSPEQAEVVWRCGNTQLRPGKRFQMTSE
                     GPRRTLTVSGLREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEAT
                     FQCVVSPSDAGVTWYKDGMQLQPSEKFVMVESGASRSLTILGLTLEDAGQVTVEAEGA
                     SSSAALRVREAPVLFKKKLEPQTVEERTSVTLEVELTRPWPEVKWTRNAAVLTPSENV
                     EIRAEGARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMRQVRLVRGLQEVEAKEQ
                     GTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGLVAFR
                     AEGVHTSARLIVTELPVSFTRVLQDVVATQKEKVTLECELSRPVDVRWLKDGVELRAG
                     KAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQGRTYTLIFRRVLAED
                     AGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFK
                     GGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSITIV
                     RGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQDGTVHRLTLHK
                     TCSTMTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAPKA
                     VQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAR
                     EVTVIQPLQDAEAMEEGRVCFSCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTL
                     VLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGTLTLQCEVSD
                     PEARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVS
                     VHDLHVGITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQ
                     GRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPLEDQRTTLGEDVML
                     SCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETEASK
                     STAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPASVVTWRKGLLELRASGKHV
                     PSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQKVRVIEDLEDTAVQEGS
                     SAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGTVYF
                     EAGDQRTSAALRVTEKPSIFSRPLTDVTVTEGEDLTLVCETTTVDSSVRWTKDGKTLR
                     PSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHALPVRFRESLKDV
                     EVPEGKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLELVIRDLQPQDSG
                     QYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTTVTLRCELTKEAPVEWKKGTE
                     TLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTSATLTVKALLVHFVRRL
                     RSKEATEGDTTTLQCELSKAAPVEWRKGTETLRDGDRYSLKQDGAVCELQIRSLTIAD
                     AGEYLCTCGQEKTSATLTVRALPAKFKDSLKNEEATEGTTATLSCELSKAAPVTWKKG
                     PKTLQSGDKYVLRQDGAVCGLQIHGLTMADAGEYSCVCGQEKTSATLTVRGLPAKFIE
                     DLRSQEATEGATAILRCELSKAAPVEWRKGSETLKDGDRYTLRQDGAVCELQIRGLAV
                     VDTGTYSSLPTKFTEGLRNEEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLR
                     QDGAMCELQIRGLTIEDSGEYTCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMA
                     TLRCQMSKAAPVEWRKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQE
                     KTSATLNVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGGRYS
                     LRQDGAVCELQIHDLDVEDAGQYSCVCGQEKTSAVLTVDALPPKFTEGLKKEEATEGT
                     MVTLRCQMSKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCG
                     QEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSKTLRDGDR
                     YSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKAPQVVFQQPLQNLQAEE
                     GSMASLRCELSVPNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSC
                     TCGSQTTSATLMVTAAPVRFLRELQAQDVDEGATARLRCELSREAVSVEWRKGSLQLF
                     PCAKYQMVQEGTTAELLVHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDLQST
                     EQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKD
                     TGEYACLVGGQKTLASLRVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWH
                     LQGLPLQSNEVTEVAVLADGCTHVLQLKGVTLEDAGTVSFHVGGLSSSAQLTVRVPEV
                     TVLEPLKDVQLSEGQDAHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQGTLYLL
                     TLHKVTLEDAGTITLQVGSCSSEAQLKVTAKNTVLRGLENVDALEGGEALFECQLSQP
                     EVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAF
                     LTVRALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHD
                     LVPGPECVVDDLVPGKTYRFRVAAVGPAGAGEPVHLPQMVKIAPAPAPAPAPAPAPAP
                     ETRQAVVGEDICLELEVAADGGEVVWHKGTERIQPGGHFEVLSRGQRQMLVIKGFRTE
                     DQGEYRCGPIQGLPSSGAATFNVVMTSGSGDEVPAQPSLPPEAAQEGDLHLLWEALAR
                     KRRMSREPTLDSISELPEEDSRVQHLRQEAEETAPDLSEGYSTADELARTGEADLSHT
                     SSDDESRAGTPSLVTYLKKAGGPGISPLASKHEAQVTTSVKPQKQQEPVVPTCPPPGD
                     LSAADLMDPSLDKAAVKIQAAFKGYKVRKEMKQQEGPVFSRTFGDTEAQVGDVLRLEC
                     VLATKTDMRACWLKDGIELTDGRHYHIDQLKDGTCSLLVTGLAPTDSGRYTCQVSTKS
                     GRVSHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKSPAELSEEELFLSA
                     DEGPGEPEEPADWQTYREDENFVCIRFESLAEARQAVTCFRNMFATMGIGVEISLGEQ
                     GPRGVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVV
                     TGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGV
                     SSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELK
                     DLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTR
                     EDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVK
                     RGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGR
                     QHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALISSFLQGTSQAVSAQMS
                     ESAGFADLVGQSKGESLVAEEAHSHLSLAEVGTEEFLQKLTSQITEMVSAKISQAKLQ
                     VPGGDSDEETKTPSASPRHGRSRPSSSVQESSSESEDGDSRGEIFDIYVVTADYLPLG
                     AEQDAIILREGQYVEVLDSAHPLRWLVRTKPTKSSPSRQGWVSPAYLDKRLKLSPEWG
                     PTEAPEFPGEAVSEDEYRTRLSSVIQELLSSEQAFVGELQFLESHHMKHLERSPRVPA
                     AVASQKTVIFRNVQDISHFHSSFLKELQGCGTDDDVAMCFIKNQEAFEKYLEFLVGRV
                     QAESVVVSTPVQEFYKKYAEETLSAKDPTQPPPPPLQHYLEQPVERVQKYQALLKELI
                     RNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQGHFIVW
                     EGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVE
                     GDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELA
                     DCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTG
                     IDSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRATPFVEGEDAQITCTVEGAPYP
                     QIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGG
                     ELYMQSPALRARDQHHREQIVAAVEGAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPI
                     VTWYKGSTQLTSSARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAELL
                     VHGGDKLDAENQVYRRKLHSFYDVQEEIGRGVFGFVKRVQHKGNKMFCAAKFIPLRSK
                     TRAQAYQERDILATLGHPLVTGLLDQFETRKTLILILELCSSEELLDRLFKKGVVTEA
                     EVKVYIQQLVEGLHYLHSHGILHLDIKPPNILMVHPAREDIKICDFGFAQKITPSEPQ
                     YSKYGSPEFVSPEIIEQNPVSEGSDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEG
                     RVSWSSPTAAHLSEDAKDFIKATLQRTPRARPSTSQCLAHPWFLKSMPAEEAHFINTK
                     QLKFLLARSRWQRSLMSYKSILVMRSIPELLQGPPDSPSLGVARHLRGEASGASSSSS
                     SSDNELAPFARAKSLPPSPVTHSPLLHPRGFLRPSASLPEETEASMPTADAAVPASPQ
                     SAGPPASPGCVPRHSVISSLFYQQAGEGAERGNKTSGAKRHPARRRHLLKGGYIARAL
                     PGLREPLMEYSLLEEEAAREEQASLMTKTPSFETALRLPSSSVREVPGRSHSLDNPPV
                     TTGPSPEACKEQLLFPPSTGLTHETTAKDRGHKEGFLQESVPFPPMSGDSRPGKQEGS
                     SQDSCRGKPASSCHSELGSGSQEGCGPPSSQSLGSLPPQSLKKELSTSCGPLFSEQPQ
                     AAPFPTQVSPLLGSEKEPQDGSLSEGPVPVPSSSPGSASQVDASLDTEGLSEAGDTCD
                     FTPPPQRPQEQATTRKFSLESRGGYAGVAGYGTFAFGGDAGGMLGQGPLWARMAWAVS
                     QSSEEQDEAATESPQPLESLGPIAEASGVPLRTSPSLTPWEEVEQVSLVQIRDLSGDA
                     EAADTISLDISEVDPAYLNLSDLYDIKYLPFEFMIFRRVPKPIEQPESPGSETEAGQG
                     LADFLEEAAWPWPGELGLRAGLEITEEPEEPGDLEALLGEAAVGRKRKWSPSRGLFQF
                     PGRCLSGEEPVELGLRQRVKASMAHISRILKGRPEGPEREGPPRKKAGLASFRLSGLK
                     GRDQELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQLL
                     TILVVKEEDLGTYTCCVSNPLGTAVTTGVLRKAERPSSSPRPEVGELYKDAVLLVWKP
                     VESCGPVTYIVQCCIEGGSWTTLASDISDCCYLTGKLSRGGMYIFRTACVSKAGMGPY
                     SSPSEQVLLGGPNHLASEEESSRGRPAQLLPSTKTFAFQMQIRRGRFSVVRQCREKAS
                     GRALAAKIVPYQPEDKTAVLREYEALKRLHHPHLAQLHAAYLSPRHLVLILELCSGPE
                     LLPSLAERESYSESDVKDYLWQMLSATQYLHAQHILHLDLRSENMMVTEYNLLKVIDL
                     GNAQSLDQEKVPAPENFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSGEYPES
                     SEGTRDLQKGLRKGLIRLSRCYAGLSGGAVAFLQSSLCAQPWGRPCASTCLQCGWLTE
                     EGPTGSRPTPVTFPTVRLRAFVREREKRRALLYKKHNLAQVR"
     exon            1..982
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1252
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1513
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1822
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            1823..2089
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            2090..2371
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            2372..2572
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            2573..2848
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            2849..3124
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            3125..3400
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            3401..3676
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            3677..3952
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            3953..4228
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            4229..4504
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            4505..4780
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            4781..5056
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            5057..5332
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            5333..5608
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            5609..5887
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            5888..6154
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            6155..6424
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            6425..6691
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            6692..6958
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            6959..7068
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            7069..7222
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            7223..7327
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            7328..7594
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            7595..7864
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            7865..8131
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            8132..8398
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            8399..8665
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            8666..8938
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            8939..9205
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            9206..9472
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            9473..9745
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            9746..10012
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            10013..10279
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            10280..10543
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            10544..10807
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            10808..11071
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            11072..11290
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            11291..11554
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            11555..11818
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            11819..12082
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            12083..12346
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            12347..12610
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            12611..12877
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            12878..13144
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            13145..13417
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            13418..13693
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            13694..13890
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            13891..13966
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            13967..14239
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            14240..14527
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            14528..14815
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            14816..15189
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            15190..16066
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            16067..16345
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            16346..16424
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            16425..16543
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            16544..16741
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            16742..16774
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            16775..16873
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            16874..17092
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            17093..17153
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            17154..17224
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            17225..17347
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            17348..17487
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            17488..17688
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            17689..17771
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            17772..17945
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            17946..18102
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            18103..18219
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            18220..18384
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            18385..18543
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            18544..18721
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            18722..18835
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            18836..19003
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19004..19106
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19107..19236
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19237..19348
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19349..19461
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19462..19630
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19631..19709
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19710..19910
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19911..19971
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            19972..20049
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            20050..20222
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            20223..20249
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            20250..20402
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            20403..20448
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            20449..20526
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            20527..22510
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22511..22591
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22592..22684
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22685..22852
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22853..22975
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            22976..23146
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            23147..23231
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            23232..23471
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            23472..23695
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            23696..23771
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            23772..23921
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
     exon            23922..24175
                     /gene="Obscn"
                     /gene_synonym="Gm878; UNC89"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggaccact ccttcagcgg agcaccccgc ttcctgacgc ggccaaaggc ctttgtggta
       61 tctgttggca aggatgccac gctgagctgc cagatcgtgg gcaaccccac gccacacgtg
      121 agctgggaga aggaccggca gccagtagag gcaggagcgc gcttccgcct ggcccaggac
      181 ggggatgtgt accgcctcac aattctcgat ctggcgctag gtgacagcgg gcagtatgtg
      241 tgtcgcgcga ggaacgccat aggggaggcc ttcgccgccg tcggcctgcg agtggactcg
      301 gagggcacgt gtgccgagca ggcgccccac tttctgctgc ggcccacatc cattcgcgtg
      361 cgcgagggcg cagacgccac cttccgatgt cgcgttggag gctcaccaca acctgctgtg
      421 agctggtcca aagatgggcg gcgcctgggc ccacccgatg ccccccatgt gcgtgtggaa
      481 gaacacgggg agtcgagcgc gcttcgcatc cgttcggcaa ggcctcgcga tggtggcacc
      541 tacgaagtcc gagcagaaaa tccgctgggc tctgccagcg ctgccgccgc tctggtggtg
      601 gactcggacg ccgaggttgc cggaccaccc ggcacctcca ccgccacgct cctggcgcac
      661 ctgcagcagc ggcgggaggc catgcgcgca gagggcatac ccccttctcc acccggcgct
      721 ggcacgcgca cctgcacggt gaccgaaggc aaacacgcgc gcctcagctg ttttgtgacc
      781 ggcgagccca agcccgagac agtgtggaag aaggacgggc agctggtgac cgagggccgg
      841 cgacacgtag tgtatgagga cgagcaagag aacttcgtcc ttaagattct tttctgcaag
      901 cagtccgacc gcggcctcta cacctgcaca gcgtccaacc tcgtgggcca gacctacagc
      961 tcggtgctgg tggtcgtgag agagccgacg gtgcccttca agaagcggct gcaggacctg
     1021 gaggtacgag agaaagagtc tgctacattc cagtgcgagg tggctcagcc agctaccgag
     1081 gcggcgtggt tcaaggagga gacccggcta tgggccagcg ccaagtacga catcgaggag
     1141 gagggcaccg agcgccggct gaccgtgcgc aacgtctcgg cagacgacga cgctgtgtac
     1201 atctgcgaga ccacagaggg cagccgcacg gtggcagagc tctctgttca aggaaacttg
     1261 accagaaagc tgcctcggaa gacagcagtg cgcactggag acacagccat cttttgggtg
     1321 gagctggctg tccccgaagg ccctgtccgg tggctacgga accaggagga gatggtggca
     1381 gggggtcggg ttgccatcac tgcagaaggc acgtgccaca cactgaccat cttccagtgc
     1441 accttggagg acatgggtga ggtggccttt gtgtctggtg gctgccggac gaccacccag
     1501 ttctgtgtat cagcgcccag gaggccaccc ctgtaccctc ctgctgaccc tgttgtaaag
     1561 gccaagacag agagttctgt gaccctcagc tggtccgcac caccccatgg ggaccgccct
     1621 gtcactattg atggctatgt gttggagaag aggaagctgg gtgcctatgc ctggagcagg
     1681 tgtcacgaag ctggatggct ggccacaact gagtttacca tcactggtgt ggctgaggag
     1741 ggggatttcc agttccgagt gtcagccatc aatcactttg gccagggtcc ttaccttgaa
     1801 tttccaggga ccatgcactt ggtccccatg ctggctgtaa agacacctct gaaggcggtg
     1861 gaggcagtgg agggtggtga ggtcactttc tccgtggacc tcacggtggc ctcttcgggc
     1921 gaatggttcc tggatgggga ggccttgaaa gcgagcagta tatacgtgat ccgttgtgac
     1981 cgcacccggc atatgctcac catcagagag gtgcccgcca gattgcatgg ggcacagctg
     2041 aagtttgtgg ctaatggcat tgaaactagc atccaaatgg tggtccgagc ggctctgggg
     2101 ctgcccagca gtaagcttcc tgctgcggct gcccgggagg tgctggccca gttgcacgag
     2161 gaggcacagc tgctggctga gctgtcggac caggctgctg ctgtgacttg gctgaaggat
     2221 ggtcgtgagc tgtccctagg gcccaagtat gagatgcagg tgtcagctgg gaggcgagca
     2281 ctgctggtgc gggacgtggc acaggatgac gctggcctct atgagtgtgt cagtcgtggg
     2341 agccgcactg cctaccagct gttggtgcaa gacataacag atggctaccg tgactggggc
     2401 ccagcaggac ctcagaagca catgtgcaag tgtgctgggg caaagatagc gagatacttg
     2461 ggttcctctt gctaccgctt cttgcagtat gacaaggggg tatggcattg gctggaggca
     2521 gctttggaca ccaggcaggg caagggtacc tcctcctgct ccctgcatga aaaacccaag
     2581 ctggtatttg ccaaggggca gcaggcacac agtgaggtga aggcagaggc gggggccagc
     2641 gccacactga gctgcgaggt ggcccaggcc cagactgagg tgacatggtt caaggacggg
     2701 aagaagctga gctccagctc gaaggtgcgc atggaggcct cgggctgctc caggaggctg
     2761 gtggtgcagc aggcgggcaa ggcggatgct ggggagtaca gctgcgaggc cgggggacag
     2821 aagctctcct tccgcctgga cgtggcagag cccaagatgg tgtttgccaa ggagcagcag
     2881 gcacgcagcg aggtgaaggc cgaggcgggg gccagcgcca cactgagctg cgaggtggcc
     2941 caggctcaga ctgaggtgac atggttcaag gacgggaaga agctgagctc cagctcgaag
     3001 gtgcgcatgg aggcctcggg ctgctccagg aggctggtgg tgcagcaggc gggcaaggca
     3061 gatgctgggg agtacagctg cgaggccggg ggacagaagc tctccttccg cctggacgtc
     3121 acagagccca agctggtgtt tgccaaggag cagcaggcac gcagtgaggt gaaggcagag
     3181 gtggggaaca gtgccacact gagctgcgag gtggcccagg cccagactga ggtgacatgg
     3241 ttcaaggacg ggaagaagct gagctccagc tcgaaggtgc gcatggaggc ctcgggctgc
     3301 tccaggaggc tggtggtgca gcaggcgggc aaggcggatg ctggggagta cagctgcgag
     3361 gccggggggc agaaactctc cttccgcctg gacgtggcag aacccaagct ggtgtttgcc
     3421 aaggagcagc aggcacgaag tgaggtgaag gcagaggcag ggaacagtgc cacactgagc
     3481 tgtgaggtgg cccaggcaca gactgaggtg acatggttca aggacgggaa gaagctgagc
     3541 tccagctcaa aggtgcgcat ggaggcctcg ggctgctcca ggaggctggt ggtgcagcag
     3601 gcgggcaagg cggatgctgg ggagtacagc tgcgaggccg ggggacagaa gctctcattc
     3661 catctggacg tcacagaacc caagctggtg tttgccaagg agcagcaggc acacagtgag
     3721 gtgaaggcag aggcgggggc cagtgccacc ctgagctgcg aggtggccca ggcccagact
     3781 gaggtgacat ggttcaagga cggaaagaag ctgagctcca gctcaaaggt gcgcatggag
     3841 gcctcgggct gctccaggag gctggtggtg cagcaggcgg gcaaggcgga tgctggggag
     3901 tacagctgcg aggccgaggg acagaagctc tccttccgcc tggacgtggc agagcccaag
     3961 ctggtgtttg ccaaggagca gcaggcacgc agcgaggtga aggcagaggc tggggccagt
     4021 gccacactga gctgtgaggt ggcccaggcc cagactgagg tgacatggtt caaggacggg
     4081 aagaagctga gctccagctc gaaggtgcga gtggaggcct cgggctgctc caggaggctg
     4141 gtggtgcagc aggcgggcaa ggcggatgct ggggagtaca gctgcgaggc cgggggccag
     4201 aagctctcct tccgcctgga cgtcgcagag cccaagctgg tgtttgccaa ggaacagcag
     4261 gcaaacagcg aggtgaaggc cgaggcgggg gccagcgcca cactgagctg cgaggtggcc
     4321 caggcccaga ctgaggtgac atggttcaag gacgggaaga agctgagctc cagctcgaag
     4381 gtgcgcgtgg aggcctcggg ctgctccagg aggctggtgg tgcagcaggc gggcaaggcg
     4441 gatgctgggg agtacagctg cgaggccggg gggcagaagc tttccttccg cctggacgtg
     4501 gcagagccca agctggcgtt tgccaaggag cagcaggcac acagcgaagt gaaggcagag
     4561 gcgggggcca gcgccacact gagctgcgag gtggcccagg cccagactga ggtgacatgg
     4621 ttcaaggatg ggaagaagct gagctccagc tcgaaggtgc gcgtggaggc ctcgggctgc
     4681 tccaggaggc tggtggtgca gcaggcgggc aaggcggatg ctggggagta cagctgcgag
     4741 gccgggggac agaagctctc attccgcctg gacgtggcag agcccaagct ggcgtttgcc
     4801 aaggagcagc aggcacacag cgaggtgaag gcagaggcgg gggccagcgc cacactgagc
     4861 tgtgaggtgg cccaggccca gactgaggtg acatggttca aggacgggaa gaagctgagc
     4921 tccagctcga aggtgcgcgt ggaggcctcg ggctgctcca ggaggctggt ggtgcagcag
     4981 gcgggcaagg cggatgctgg ggagtacagc tgcgaggccg ggggtcagaa gctctccttc
     5041 cgcctggacg tggcagagcc taagctggcg tttgccaagg aacagcaggc acacagcgag
     5101 gtgaaggcag aggcgggggc cagtgccaca ctgagctgcg aggtggccca ggcccagact
     5161 gaggtgacat ggttcaagga cgggaagaag ctgagctcca gctcgaaggt gcgcgtggag
     5221 gcctcgggct gctccaggag gctggtggtg cagcaggcgg gcaaggcgga tgctggggag
     5281 tacagctgcg aggccggggg acagaagctc ttcttccgcc tggatgtggc agagcccaag
     5341 ctggtgtttg ccaaggagca gcaggcacac agtgaggtga aggccgaggc gggggccagc
     5401 gccaccctga gctgcgaggt ggcccaggcc cagactgagg tgacatggtt caaggacggg
     5461 aagaagctga gctccagctc gaaggtgcgc gtggaggcct cgggctgctc caggaggctg
     5521 gtggtgcagc aggtgggcaa ggcggatgct ggggagtaca gctgcgaggc caggggacag
     5581 aagctctcct tccgcctgga cgtggcagag gccgaatccc agattccgga gagacccagc
     5641 cgcagggaac ctctggttgt caaggaacat gagaccatta tcctgactgc cacaatagct
     5701 gcaccctctg tggctgctgt gacctggctc aaagatggag tggagatccg ccgcagtaag
     5761 cggcatgagg ccaccagtct gggtgatacc cataccctga ccgtgagagg cgcacaggtc
     5821 ctggacagtg ccatctacag ctgccgtgtt ggcaaggaag gtcaggactt cccggtgcag
     5881 gtagaagagg tggccgccaa gttctccaaa cccctggagc ccgtcgaagg ggagctgggt
     5941 ggcaccgtga tgctggtttg tgagctgagc ccggagcagg ctgaggttgt gtggcgctgt
     6001 gggaacacac agctgcggcc aggcaagcgc ttccagatga catcagaggg gcctaggcgc
     6061 acgctgaccg tgtctggcct tcgagaggat gacgcagagg agtatgtgtg tgagagccgg
     6121 gatgaccgca ccagcgcacg gctcactgtt aaagttcccc gagtggtcaa gtttacgtct
     6181 ggattgagtg ccatggtcgc agaggagggc caagaggcca cctttcagtg tgtcgtgtcc
     6241 cccagcgatg caggggtcac atggtacaag gacgggatgc agctgcagcc tagcgagaag
     6301 tttgttatgg tagagagtgg ggccagccgc agcttgacta tcttgggcct gaccctggag
     6361 gatgccggtc aagtcacagt ggaggctgag ggggcttcat cttctgctgc cctccgggtc
     6421 cgagaggcac cggtcctctt caaaaagaag ctggagccac agacagtgga ggagaggacc
     6481 tctgtgacat tggaggtgga gctgacgcgg ccctggcccg aggtgaagtg gacacggaat
     6541 gctgccgtcc tgacacccag cgagaacgtg gagatccgcg ctgagggtgc tcggcactgt
     6601 ctggtgctgc gcagcgtggg ctttgctgac cgcggcttct ttggctgtga gacaccagat
     6661 gataagactc aggccaagct caatgtagaa atgcggcagg tccggctggt tcgcggtctg
     6721 caggaggtgg aggctaagga acagggcacg gcctcgatgg atgtggagct gtcccatgcc
     6781 gaggtggagg gcagctggac ccgagatggc ctgcgacttc agcctggacc caaatgccac
     6841 ctggccgtac aaggccctgt ccacatcctc acactctcgg cgctgcagcc acaggacagt
     6901 gggctggtgg ccttcagggc cgagggcgtg cacacgtctg cgaggctcat agtcactgag
     6961 ttgcccgtga gcttcaccag agtactacag gatgtggtgg ccacgcagaa ggagaaggtc
     7021 accctggagt gtgagctgtc gaggcctgtg gatgtgcgct ggctgaagga tggtgtggag
     7081 ctgcgggcag gcaaggccat aggcatagtg gcccagggaa cctgcaggag tctcgttatc
     7141 taccgctgtg agactgggga ccagggtgtc tatgtatgtg atgctcttga tgctcagacc
     7201 tctgcctctc tgagggtgca agggaggaca tacacgctta tcttccggag ggtactggca
     7261 gaggatgcag gggaggtcaa gtttgtagct gagaacgcag aatcaagagc tcacctccga
     7321 gtgaaagaac tgcccgtgac cctcctgcgc ccactgaggg acaagattgc catggaaaaa
     7381 caccgtggag tgctggagtg ccaggtgtcc cgggctagtg cccaggtgcg gtggttcaag
     7441 ggcggagtcg agctgcagtc tgggcccaag tacgaggtgg tcagtgacgg cctttaccgc
     7501 aagctggtca ttaatgacgt gcagcctgag gatgaagata cgtacacctg tgacgctggc
     7561 aacgtcaaga ccagtgccca gttctttgtg gaagagcaat ccatcactat tgtgcgggga
     7621 ctgaaggaca tgacagtgat ggagcctgcc cctgcctggt ttgaatgtga gacatccatc
     7681 ccttccgtga ggccacccaa gtggctcctt ggtaagactg tgctccaggc aggggggaac
     7741 gtgggactgg agcaagacgg caccgtgcac cggctgacac tgcacaagac ctgctctacc
     7801 atgaccgggc ctgtgcactt cactatcggc aagtcccgct cctctgccca gctggttgtc
     7861 tcagacattc ctgtggtact gacacggcct ctggagccca aagcagggcg tgaactgcag
     7921 tcagtagtcc tgtcctgtga cttcaggcca gcccccaagg ctgtgcagtg gtacaaggat
     7981 gacacacccc tgtccccgtc agaaaagttc aagatggcgc tggagggcca gatggcagag
     8041 ctgcgcatac tccggctcac gccagctgat gctggggtct accggtgcca ggcgggtagc
     8101 gcccagagca gtgctgaggt tactgtggaa gctcgggagg tgacagtgat tcagccactg
     8161 caggatgcag aagccatgga ggaaggccgg gtctgcttct cctgcgagct gtcccataag
     8221 gatgaagata tcgaatggtc actcaatggt acacccctgt acaatgacag cttccatgag
     8281 atcagccatg agggctgtct ccacaccctg gtgctgaaga gtgtccggca ggctgacaca
     8341 ggcaccgtgt gcgccacctc ccccaaggtg tccgtttccg cccggctggt ggttaaaggc
     8401 aagccagtgg tgttcctgaa agcactggat gacgtatctg cagaagagcg tggcacgctg
     8461 accctgcaat gcgaggtctc cgaccccgag gcacgcgtgg tttggcgcaa agatggtgtg
     8521 gagcttggtc ccagcgacaa gtatgatttc ctacataagg caggtgcccg gggccttacg
     8581 gtccatgacc tgagccatga ggatgctgga ctgtacacct gccaggtggg cagtaaggag
     8641 acccagtcca aggtcagcgt acatgatctt cacgtgggca tcaccaagag gttaaagaca
     8701 gtggaggtgc tggagggaga gagctgcagc tttgagtgtg tcctttccca cgagagtccc
     8761 agtgacccag cagtgtggac ggtcggtggg aagacagtgg gtggttctgg ccactttcac
     8821 gccgttcggc agggccgcaa atacaccctg acagtcaaag atgctgcact cagtgatgca
     8881 ggagaggtgg tcttctcggt gctgggcctc acttccaagg cctcgctcat catcagagag
     8941 aggccagtgg acatcaccaa gcccctggag gaccagcgga cgacgcttgg ggaagatgta
     9001 atgctaagct gtgagctgtc cagggcaggc acctctgtgc gctggctgaa agacgggaag
     9061 gccatcagga agagccagaa gtatgacctg ctcagtgaag gcacgcgggc tgtgttggtt
     9121 gtccgcaagg cctcactcaa ggattcaggg gaatacacct gcgagacaga agcttcgaaa
     9181 agcactgcca agctctgtgt ggaagaaaag gcaaaccggt tcacggagga gctggctgac
     9241 ctgcaggtgg aagagaaggg cagagctgtg ttcacatgca agacagagca cccagcatct
     9301 gtcgtgacct ggcgcaaagg cctcctggag ctgcgcgcct cagggaagca tgtccccagt
     9361 caggaaggct tgaccctgaa gctcaccatc aacgccctgg agaggacaga cagtgacact
     9421 tacacctgtg acatcggcca agcccggacc caggcacggc tcctcgtcca cggccagaaa
     9481 gtgcgcgtta ttgaggacct agaggacact gctgtccagg agggctcctc tgctaagttt
     9541 tgctgccgca tcgctcctgc tgactacggc cccgtgcact ggttcctgga taagaccccc
     9601 ttgcacagca atgagctgaa tgagatcact gtccagcctg gaggctatca cgtgctcacc
     9661 ctgcggcagc tggcactcaa ggactcaggc actgtctact ttgaggcggg tgaccagcga
     9721 acctcagctg ccctgcgggt gactgagaag ccgagcatct tctctcggcc actcacagac
     9781 gtcacagtca cagaaggcga ggacctgact ctggtctgtg aaaccaccac tgtggatagc
     9841 tctgtgcgct ggaccaaaga tgggaagaca ctgaggccgt ctgcacgatg ccagctgagc
     9901 catgaaggct gtcaggccca gctgctcatc actgccacca ccccacaaga tggtgggcgg
     9961 tacaaatgtg agattggtgg agcctccagc agctccattg tcagggtcca tgctctgcca
    10021 gtgcggttca gggagtccct gaaggacgtg gaggtaccag agggcaaggc cgccacactg
    10081 cgctgtgtgc tgtcatccgt ggctgcacct gtggagtggc gtcatggaga tgatgtcctg
    10141 aaatccagca acaagtatag cctgcgccaa gagggtgctg tgctggaatt ggtcatccga
    10201 gacctgcagc cccaggacag tgggcaatac tcatgctcct ttggggacca gacaacttca
    10261 gccacactca cagtgaaaac ctcttctgcc cagttcgtag ggaaactgag aaacaaggag
    10321 gccacagaag ggaccacggt cacacttcgg tgtgagctga ccaaagaggc ccccgtggag
    10381 tggaagaagg gaacagagac cctgagaaat ggggacaaat acagtctgaa gcaggatgga
    10441 gctgtgtgtg agctgcagat ctgtagtctg ctggtggcag atgcagggga gtactcgtgt
    10501 gtgtgtgggc aggagaagac ttcagccacg ctgactgtca aggctctgct tgtccacttt
    10561 gtcagaaggc tcaggagcaa ggaggccaca gaaggagaca cgaccacact gcagtgtgaa
    10621 ctgagcaagg ctgcccccgt ggagtggagg aagggaacag agaccctgag agatggggac
    10681 agatacagcc tgaagcagga tggggctgtg tgtgagctgc aaatccgcag cctgaccata
    10741 gcagatgctg gcgagtactt gtgcacgtgt ggacaggaaa agacctcagc cacgctgacc
    10801 gtcagggccc ttccagctaa gttcaaagac agtctgaaga atgaagaggc tacagaaggc
    10861 accacagcta cactgagctg tgaactgagc aaggcagctc cggtgacatg gaagaaagga
    10921 ccgaagacct tgcaaagtgg agacaaatat gtcctgaggc aggatggagc tgtgtgtgga
    10981 ctacagatcc atggcctgac catggctgat gctggggagt actcgtgtgt gtgtgggcag
    11041 gagaagacgt cagccacgct gactgtcagg ggcttgcctg ccaaatttat agaagatctg
    11101 agaagccaag aagccacaga aggggccaca gcaatcttaa gatgtgagct gagcaaggct
    11161 gctcctgtgg agtggaggaa agggtctgag accctgaaag atggggacag atacaccctg
    11221 aggcaggatg gggccgtatg tgagctgcag atccgtggcc tggctgtggt ggatactggg
    11281 acatactcgt ccctgcccac caagttcaca gagggtctga ggaatgaaga ggccacggaa
    11341 ggcaccatgg ccactctgag gtgccagatg agcaaggctg cccctgtgga gtggaggaag
    11401 gggtcagaga ccctgagaga tggggacaga tacagcctga ggcaggatgg ggccatgtgt
    11461 gagctgcaga tccgtggcct gaccatagaa gattctgggg agtacacatg tgtgtgtggg
    11521 caggagaaga cgtcagccac actgagtgtc aaggctctgc cccccagatt catagaagac
    11581 ttgagaagcc aagaggccac agaaggcacc atggccactc tgaggtgcca gatgagcaag
    11641 gcagcccctg tggagtggag gaaggggtct gaaaccctgg gagatggggg cagatacagc
    11701 ctgaggcaga atggtgctgt gtgtgagctg cagatccatg acctggctgt ggaagacact
    11761 ggggagtact catgtgtgtg tgggcaggag aagacctcag ccacactgaa tgtcaaggcc
    11821 ctgcccccca gattcataga agacttgaga agccaagagg ccacagaagg caccatggcc
    11881 actctgaggt gccagatgag caaggcagcc cctgtggagt ggaggaaggg gtctgagacc
    11941 ctgagagatg ggggcagata cagcctgagg caggatgggg ctgtgtgtga gctgcagatc
    12001 catgacctgg atgtggaaga tgctggccag tactcgtgcg tgtgtgggca ggagaagacc
    12061 tcagccgtgc tgactgtaga tgcactgccc cccaagttta cagagggtct gaagaaggaa
    12121 gaggccacag aagggaccat ggtaacactg aggtgccaga tgagcaaaga agccacggtg
    12181 gagtggagga agggagcaaa gaccctcagc gatgggggca gatacagcct gaggcaggat
    12241 ggggccatgt gtgagctgca gatctgtggc ctggctgtgg aagacgctgg ggaatactca
    12301 tgtgtgtgtg ggcaggagaa gacctcagcc acactgagtg tcaaggccct gccccccaga
    12361 ttcatagaag acttgagaag ccaagaggcc acagaaggca ccatggccac tctgaggtgc
    12421 cagatgagca aggctgcccc tgtggagtgg aggaagggat ccaagaccct gagagatggg
    12481 gacagataca gcctgaggca ggatggggcc atgtgtgagc tgcagatctg tgacctggct
    12541 gtggaagaca ctggggacta ctcatgtgtg tgtgggcagg agaagacctc agccacactg
    12601 agtgtcaagg ctccacaggt ggtattccag cagccactgc agaatctgca agcagaagaa
    12661 ggctccatgg ccagcctgcg gtgtgagttg tcagtcccca acgctgccat ggtctggagc
    12721 aagggtggtc tggagctgca gggtgacacg cgccgagagg cacggcagca ggggtgtgtg
    12781 gcagagctgt tgcttaggga cctgcgtcgc gaggatgcgg gcgagtacag ttgcacctgt
    12841 ggctctcaga ccacaagcgc cacgctcatg gtcacagctg ctcctgtgcg gttcctccgg
    12901 gaactgcagg cccaggacgt agatgagggg gccaccgcac gcctgcgctg tgagctgagc
    12961 cgggaggctg tgagcgtgga gtggcgcaag ggctccttgc aactttttcc ttgtgctaag
    13021 tatcagatgg tgcaggaggg cacaactgcg gagctgctgg tccatggggt ggagcaggag
    13081 gatgcaggcg aatacacctg cgatgcaggc cacacgcaga gcattgccag gctctctgtc
    13141 cgagccccca agcccaagtt caagaccgac ctgcaaagca cagagcagga agcaggtggc
    13201 acggcacggc tgtgttgtca actgagcgaa gctgagccag ggactccagt gcagtggctc
    13261 aaggaggggg tggagctgca cgtcggctcc aagtatgaga tgcggcgcca aggggctgtg
    13321 tgcgagctgc tgatccatgg gctggaggcc aaggacactg gagaatatgc ctgcctggtg
    13381 ggtggccaga agaccttggc ctccctcaga gtcaaagagc ctgaggtgac catcgtgcgg
    13441 ggactcgtgg acatggaggt gcaggccgat gaggatgtgg agttcacttg caaggtgtca
    13501 caggcaggag ccacagacgt gcagtggcac ctccaaggtc tgccactgca gagcaatgaa
    13561 gtgacagagg tggctgtcct tgcggacggc tgtacccatg tgctccagtt aaagggtgtg
    13621 acactggagg atgctggtac tgtctccttc cacgtgggcg gcctttcatc ttctgctcag
    13681 ctcacagtcc gagtccctga ggtgaccgtt ctggagcccc tgaaggatgt gcagctcagc
    13741 gagggccagg atgcccactt ccggtgccga ctgtccaggg cctcgggcca ggaggctcgc
    13801 tgggctttgg gaggggttcc cttgcagtgc aacgagatga acgacatcac tgtggagcag
    13861 ggcacactct acctgctcac tctgcacaag gtgaccctgg aggatgctgg gaccatcact
    13921 ctccaagtgg gctcatgctc ctcagaggcc cagctgaagg tcacagccaa gaacacggtg
    13981 ttgcgtggcc tggagaacgt ggatgcactg gagggcggtg aggctctgtt cgagtgccag
    14041 ctgtcccagc ctgaagtggc cgcccacacc tggctgctgg acgacgagcc tgtgcacacg
    14101 tcggagaagg tggaggtggt ctactttgag aacggactgc ggcacctgct tctactcaaa
    14161 aacctgaagc cacaggacag ctgccgagtg accttcctgg caggggatgt ggtcacgtcc
    14221 gcattcctca ctgtgagagc tcttcctgac ccccctgaag atgctgaagt ggtggggcgt
    14281 agtgaccatt ctgtgaccct atcctgggtg gctcccatga gtgatggagg tgggggtcta
    14341 tgtggttatc gtgtggagat gaaggaggca tccacaggcc agtggcagtt gtgccatgac
    14401 ttggtacctg gtccagagtg cgtggtggac gacctggtcc ccgggaagac ctaccgcttc
    14461 cgagtggcag ctgtgggtcc agcaggtgct ggggagcctg tacacttgcc ccagatggtc
    14521 aagatagccc cagccccggc cccggccccg gcccctgccc cagcccctgc cccagaaaca
    14581 cggcaggcag tagttggtga agacatctgt ctggagttgg aagtggcagc tgatggtggc
    14641 gaggtcgtct ggcacaaggg aacagagcgc atccagcccg gagggcactt tgaggtcctc
    14701 tctcggggtc agcggcagat gctggtgatc aagggcttta ggaccgaaga ccaaggggag
    14761 taccgctgtg gtcccattca gggtctgccc tcctcaggag ctgccacgtt caatgtggtc
    14821 atgacctcag gctctgggga tgaggtcccg gcacagccta gcctgcctcc cgaggcagcc
    14881 caggagggtg acctgcatct gctttgggag gcccttgccc ggaagcgccg catgagtcgg
    14941 gagcccacgc tggactccat cagtgagctg cctgaggaag acagccgtgt gcagcatctg
    15001 cggcaggagg cagaagagac agctcccgac ctctctgaag gctactctac agcggatgag
    15061 ctagcacgca caggagaggc cgacctctca cacaccagct ctgacgatga gtctcgggct
    15121 ggcacccctt ccctagttac ctacctcaag aaggccgggg gtcctgggat ctcacccttg
    15181 gccagcaagc atgaggccca ggtgaccacg tctgtgaagc cacaaaagca gcaggagcca
    15241 gtcgtgccca cgtgcccacc gccgggagac ttgagtgcag cagatttgat ggatccatcc
    15301 ctggacaagg ctgctgtgaa gattcaggct gcctttaagg gttacaaagt gcggaaggag
    15361 atgaaacagc aggaagggcc tgtgttctca cgaacatttg gggacacaga ggcacaggtt
    15421 ggggatgtgc tgcggctaga gtgtgtgctg gccaccaaga ctgatatgcg ggcctgctgg
    15481 ttgaaggatg gcatcgagtt aacagatggg cgccattacc acatagacca gctcaaggat
    15541 ggtacctgct ctctgctggt cactggcctg gcccccactg actctggccg ttacacctgt
    15601 caggtgagca ccaagtctgg ccgtgtgagc cacagtgcct gcgtggtggt cagtgggaca
    15661 gagagcgagg ccgagagctc ctctgggggc gagctggatg atgctttccg ccgggcagcg
    15721 agacgcctgc accgcctctt ccgcaccaag agcccagctg agctttcaga ggaggaactc
    15781 ttcctcagcg ctgatgaagg ccccggggag ccagaggagc ccgcagactg gcaaacatac
    15841 cgagaggatg agaactttgt gtgcatccgt tttgagtccc ttgcagaggc ccgccaggca
    15901 gtcacctgct tccgaaacat gtttgccact atgggcatcg gggtggagat cagcctaggg
    15961 gagcagggac cccggggagt ggagatgcgc atcggcaagg tggcccctac tgtcacccct
    16021 gcagtgccgc ttgcaaagac acctggcctg cagacttcag atgctgcccc agtgttcctg
    16081 accgagctgc agaaccaaga tgtgcaggat ggatacccca tgagcttcga ctgcgtggta
    16141 acgggccagc ctgtgcccag tgtgcgctgg ttcaaggatg ggaagctgct agaagaggat
    16201 gaccactata tgatcaatga ggaccaacag gggggtcacc agctcatcat cacagctgtg
    16261 gtgccggcag acatgggtgt ctaccgctgc ctggcggaga acagcatggg cgtctcctcc
    16321 accaaggctg agcttcgtgt ggaattgacc agcacagact atgatactgc tgcggatgct
    16381 actgagacct catcctactt cagcgcccag ggatacctgt ccagtcggga gcaagaggga
    16441 acggagtcag atgaggggca gcttccccag gtgctggagg aactgaaaga cctccaagtg
    16501 gcccccggga cacgcctggc caagttccag ctcaaggtga aaggctatcc agctcccaaa
    16561 ctgtattggt tcaaagatgg ccagcccctg accacgtctg accacatccg catgactgac
    16621 aagaagaccc tgcacaccct ggagattgtc tcggtcactc gggaggacag cggccagtat
    16681 gcagcctaca tcagcaatgc tgtgggtgct gcctattcgt cagcccggct tctggtccga
    16741 ggtcccagtg aaccagaaga gaagccagca tcagatgttc atgagaggct ggtgccaccc
    16801 cgaatcctgg agaagttcac ccccaagaaa gtgaagaggg gctccagcat caccttttca
    16861 gtgaaggtgg aaggacaccc ggcccccagt gtgcattggc tcaaggagga ggcagagaag
    16921 ggagtcctgt ggattggccc tgacaccccg ggctacacca tggccagctc ttccaagcag
    16981 catagcctgg tcctgctgga cgtaggccga cagcaccagg gcacctacac atgtattgct
    17041 accaaccctg ctggccaggc gctctgctct gccagcctgc acatctctgg cttggccaaa
    17101 gaagaagagc aggagagagt gaaggaggcc ctcatttcct ctttcctgca agggacaagc
    17161 caagctgtct cagcccagat gtcagaatcc gcaggttttg ctgatcttgt cgggcaaagc
    17221 aaaggcgagt ctctggtggc tgaggaggcc cacagtcacc tgtcccttgc tgaggtgggc
    17281 actgaagagt tcctgcagaa actcacctcg cagatcacgg agatggtatc ggccaagatc
    17341 tctcaggcca aactccaggt gcctggaggt gacagcgatg aagagaccaa gacaccatct
    17401 gcttctcctc ggcatggccg gtcacgtcct tcctccagtg ttcaagagtc ctcctcagag
    17461 tcagaggatg gggactcccg tggtgagatc tttgacatct atgtggtcac agctgactat
    17521 ctgccactgg gagctgagca ggatgccatc attctgagag aaggccagta tgtggaggtc
    17581 cttgactctg cccatcccct gcgctggctt gtccggacca agcccaccaa atccagtcct
    17641 tccaggcagg gctgggtgtc acctgcctac ctggataaga ggctcaagct gtctcctgag
    17701 tgggggccca ctgaggcccc cgagttccct ggcgaggctg tgtctgagga tgagtataga
    17761 acgaggctga gctctgtcat ccaggagttg ctgagttcag agcaggcttt tgtgggtgag
    17821 ctgcagttct tggagagcca ccacatgaag cacctggagc gatctccccg agtacccgca
    17881 gctgtggcca gccagaagac agtcatcttt cgtaatgtgc aggacatcag ccatttccac
    17941 agcagcttct tgaaggagct gcagggctgt ggcaccgacg atgatgtggc catgtgcttc
    18001 atcaagaacc aggaggcctt tgagaagtac ctcgagttcc tggtgggccg cgtgcaagct
    18061 gaatcagtgg ttgtcagcac cccagtccag gagttctaca agaaatatgc agaagagaca
    18121 ctgtcagcca aggaccccac acagccaccc ccacctcctc ttcagcacta cctggagcag
    18181 ccagtggaac gggtgcagaa ataccaggcc ttgctgaagg agctaatccg caacaaggcc
    18241 cgcaaccggc agaactgcgc gctgctggag caggcctatg ctgtggtgtc tgccctgcct
    18301 cagcgcgccg agaacaagct gcacgtttct ctcatggaga actacccagg aaccctggag
    18361 gccctgggag aacctatccg ccagggccac ttcatagtgt gggagggggc cccaggggcc
    18421 cggatgcctt ggaagggcca caaccggcac gtcttcctct tccgaaacta cctggtgatc
    18481 tgcaagcccc gaagagactc tcgaaccgac accttcagct atgtgttccg gaacatgatg
    18541 aagctgagta gcatcgacct gaatgaccaa gtagaggggg atgaccgcgc ctttgaggtg
    18601 tggcacgaac gggaagactc tgtgcgcaag tacctgctgc aggcacggac cgtcatcatc
    18661 aaaaactcct gggtgaagga gatctgtggc atccagcagc gcctggccca gcctgtgtgg
    18721 cgtccccctg agtttgaaga ggaactagcg gactgcacag ccgagctggg tgaaacggtc
    18781 aagctagcat gccgagtgac gggcacacct aagcctattg tcagctggta caaagatggg
    18841 aagccagtgg aggtggaccc acaccacatc ctcattgaag accctgacgg ctcctgcacc
    18901 ctcatcttgg acaaccttac tggcatagac tctggccagt acatgtgttt tgcggccagt
    18961 gctgctggca acgccagcac cttggggaag attctagtac aagtgccccc acggtttgtg
    19021 aacaaggtcc gggccacacc ctttgtggag ggagaggatg cacagatcac ctgcacagtg
    19081 gaaggagccc cgtaccctca gatcaggtgg tacaaggatg gtaccctgct agccccgggc
    19141 aacaggtacc ggatgttgaa tgaaccccgc agtggtgtgc tggtgctggt gatccaggcg
    19201 gccagcaagg aggacctggg acactatgaa tgtgagttgg tgaaccggtt gggctcaaca
    19261 cgtggtggtg gagaactata catgcagagc cctgcactgc gtgcccggga ccagcaccac
    19321 cgggaacaga ttgtggctgc cgtagaaggg gccccgtcca tgcaggtcac tattgaggat
    19381 gtacaagtac aagtagggga catggcacag tttgatgctg tcattgaagg ccacccacca
    19441 cccatagtaa cctggtacaa gggcagcacc cagctgacga gcagtgcccg gctgagccaa
    19501 cggcaagatg gaacgacata ctccttggtg ttgactgacg tggctccaca cgatgccggt
    19561 gtctacacat gtgttgccaa taatgcaggt ggacaggtgc tctgcaaggc agagctgctg
    19621 gtccatgggg gggacaagct agatgccgaa aatcaagtct atcggagaaa actgcattcc
    19681 ttctatgacg ttcaagaaga gattgggagg ggtgtgtttg ggtttgtgaa aagggttcag
    19741 cacaaaggaa acaagatgtt ctgtgccgcc aagttcatcc ccctacggag taaaactcgg
    19801 gcccaggcat accaggaacg agacatcttg gctacactcg gccacccact ggtcactggg
    19861 ctcctggatc aatttgagac ccggaagact ctcatcctta tcttggaact gtgctcgtct
    19921 gaggagctgc tggatcggct cttcaagaag ggtgtagtga ctgaagccga ggtcaaagtc
    19981 tatatccagc agctggtgga aggcctacac tatttgcaca gccatggtat cctccacctg
    20041 gacataaagc cccccaacat cctgatggtg cacccagctc gggaagacat caagatctgt
    20101 gactttggct ttgcccaaaa gatcacccct tcagagccac agtacagcaa gtatggctca
    20161 cccgaattcg tgtccccaga gatcattgag cagaatcctg tgagcgaggg ctcagacatc
    20221 tgggccatgg gcgtcatctc ctacctcagc ctcacctgct catccccatt tgctggagag
    20281 agtgaccgcg ccaccttgct caatgttttg gaggggcggg tctcctggag cagtcccacg
    20341 gctgctcatc tgagtgagga cgccaaggac ttcatcaagg ccacgctgca aaggaccccc
    20401 agggccaggc ctagtacttc ccagtgcctt gcccacccct ggttcctgaa atccatgcct
    20461 gctgaggagg cccacttcat caacaccaaa cagctcaagt tccttcttgc tcgaagtcgc
    20521 tggcagcgtt ccttgatgag ctacaagtct atcctggtga tgcgctccat ccctgagctg
    20581 cttcagggtc ccccagacag tccatctcta ggagtggccc ggcacctacg aggggaagcc
    20641 agtggcgcct ctagctcatc atcttcctca gacaacgagc ttgccccatt tgccagggct
    20701 aagtcgctgc caccttctcc tgtgactcac tcgccactgc tgcaccctcg gggctttctg
    20761 cggccttcgg ccagcctccc agaggagaca gaggccagca tgcccactgc tgatgcggcc
    20821 gtgccagcgt ccccacagag tgctgggcct ccggcaagcc caggttgtgt gccccggcac
    20881 agcgtcatca gcagcctgtt ctaccagcaa gctggcgagg gtgcagagcg tgggaacaaa
    20941 acatcgggtg ccaagaggca ccctgcgcgg aggcggcacc tgctaaaggg tgggtacatt
    21001 gcaagggcct tacccggtct gcgtgagccc ctcatggagt acagcttgtt ggaggaagag
    21061 gcggctaggg aagagcaggc ctctctgatg accaagacac cctcctttga gactgccctg
    21121 cgactaccta gttccagtgt cagagaggtc ccaggccgaa gccactccct ggacaaccca
    21181 ccagtcacga ctggcccctc tcctgaggca tgcaaggaac aactcctgtt cccaccctcc
    21241 acggggttga ctcatgaaac cactgccaag gacagggggc acaaagaggg gttcttgcag
    21301 gagtctgtcc cctttccacc tatgagtggt gactcgaggc ctgggaagca agagggatca
    21361 tcccaggaca gttgtagagg gaaaccagcc tcttcctgtc actctgagct gggttctggt
    21421 tcccaggagg gctgtggccc tccatcatct caatcgcttg gctccttacc tccacagtca
    21481 ttgaagaagg agctctcaac gtcctgtggc ccactctttt cagaacagcc tcaggcagcc
    21541 ccattcccaa ctcaagtaag cccccttctg ggttctgaga aggaacctca ggatggctct
    21601 ctatctgaag ggccagttcc agttccctcc agttctccag ggtcagcttc ccaagtagat
    21661 gcatccttgg atactgaagg cttgtctgaa gctggggaca catgtgactt cacgcctcct
    21721 ccacagcggc ctcaggagca ggccaccacc cggaagttct ctctggagtc ccgtgggggc
    21781 tatgcagggg tggcaggcta tggtactttt gcctttggcg gggatgcagg ggggatgcta
    21841 gggcagggtc ctctctgggc caggatggcc tgggctgtgt cccagtcctc agaagagcag
    21901 gatgaagctg cgactgagag ccctcaacct ctggagagct tggggcccat tgctgaggcc
    21961 agtggggttc ccctaaggac ctctccaagc ctcacccctt gggaggaagt tgagcaggtt
    22021 tccctggtgc agatccggga tctgtctggt gatgcggaag cagctgacac tatctccttg
    22081 gacatttctg aggtcgatcc tgcctacctc aacctctcgg atctatatga catcaaatat
    22141 ctcccatttg agttcatgat cttcagaagg gtccccaaac ctatagagca gccagagtca
    22201 cctggctcag aaaccgaagc tgggcaaggg ctggcagatt tcctggagga ggccgcgtgg
    22261 ccctggccag gcgagctggg actgcgtgct ggtctggaga ttacagagga gccggaggag
    22321 ccaggggacc tggaagcact gctgggcgag gctgctgtgg gcaggaagcg caagtggtcc
    22381 ccctcccggg gcctcttcca attccctggg aggtgcctgt caggggagga gcctgtggag
    22441 cttgggctgc gccagagggt gaaggcttcc atggctcaca tctccaggat cctcaagggc
    22501 aggccggaag gtcctgagag ggaagggcct cccagaaaga aggcaggcct agcttctttc
    22561 cggctgtcag gcctgaaggg cagggaccaa gaactctcag acgaggctgt ggtcctgggc
    22621 caatcagtga cactggcctg ccaggtgttg gcccagccaa ctgcccaggc tacctggagc
    22681 aaagatgggg tcctcctgga gagcagcggc cacctcctca tctcctccac cctgaagaac
    22741 ttccagctgc tgaccatcct ggtggtgaaa gaggaggatc tgggcacata tacctgctgt
    22801 gtgagcaacc cgctggggac agcagtcacc acaggtgtcc tccggaaagc agagcgccct
    22861 tcatcttctc cacgccctga ggtgggggaa ctatacaagg atgcggtgct gctggtctgg
    22921 aagcctgtgg aatcctgtgg cccggtgacc tacattgtgc agtgctgtat agaaggaggc
    22981 agctggacaa ccctggcttc agacatctct gactgctgct acctcactgg caagctatcg
    23041 aggggtggca tgtatatctt ccggacagca tgtgtcagca aagcaggaat gggcccctac
    23101 agcagcccct cagaacaggt cctcctcgga ggacccaacc acctggcctc tgaggaggaa
    23161 agcagccggg ggaggccagc ccagcttctc cccagcacaa agacctttgc cttccagatg
    23221 cagatccgga ggggccgctt cagtgtggtg cggcagtgca gggagaaggc aagtgggcgg
    23281 gccctagctg ctaagatcgt tccctaccaa cctgaggaca agacagctgt actaagagaa
    23341 tacgaggcac ttaagagact gcaccaccca catctggccc aactccatgc cgcctacctc
    23401 agtccccggc acctggtgct catcctggag ctgtgctctg gccctgagct gctaccctct
    23461 ttggcagaga gggaatccta ctcagagtct gatgtgaagg actacctgtg gcagatgctg
    23521 agtgccaccc agtacctgca tgcccaacac atcctgcacc tggacctgag gtccgagaac
    23581 atgatggtca ctgagtacaa cctgcttaag gttatagacc tgggaaatgc ccagagtctc
    23641 gaccaagaga aggtcccagc ccctgagaac ttcaaagact acctggagac catggctcca
    23701 gaactcctgg aaggtcaagg ggctgttcca cagacagaca tttgggctat tggtgtaaca
    23761 gccttcatta tgctgagtgg cgagtaccca gagagcagcg aggggactcg cgacctgcag
    23821 aaaggcttgc gcaagggact cattcggttg agtcgctgct atgcaggatt atcaggagga
    23881 gccgtagcct tcctgcagag ttcattatgt gctcaaccct ggggccgccc gtgcgcttcc
    23941 acctgcttgc aatgcggatg gctgacagag gagggcccca ccggctcccg gcccacgccc
    24001 gtaaccttcc ccaccgtgcg gttgcgcgcc tttgtgcgcg agcgcgagaa gcggcgtgcg
    24061 ctcctctaca agaagcataa cctggcccag gtgcgctgag gtccagctct acagagcaag
    24121 atgtgccatg ccacatgcgg ggacacccgc taataaaaga tgcaaaacgg ccaaa
//
